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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Fenovast 10mg/145mg Tablet is used in the treatment of high lipid levels (cholesterol and triglycerides levels) and prevention of heart diseases and blood vessel blockage. It contains Atorvastatin and Fenofibrate, which lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). In some cases, you may experience allergic reactions, hyperglycemia (excess of glucose in the bloodstream), headache, blurred vision, stomach pain, constipation, headaches, joint swelling (oedema), joint pain, muscle pain, back pain, slow heart rate, and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Psyco Remedies Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Fenovast 10mg/145mg Tablet

Fenovast 10mg/145mg Tablet is indicated in the treatment of hyperlipidemia (high lipid levels), mixed dyslipidemia (low good cholesterol and high bad cholesterol and triglycerides), hypercholesterolemia (high cholesterol) and hypertriglyceridemia (high levels of triglycerides).

Fenovast 10mg/145mg Tablet contains atorvastatin and fenofibrate. Atorvastatin reduces cholesterol production in the liver. Fenofibrate works by lowering the level of triglycerides in the blood and bad cholesterol. Together, Fenovast 10mg/145mg Tablet helps treat high cholesterol levels.

In some cases, you may experience side effects like headache, blurred vision, stomach pain, constipation, joint swelling (oedema), joint pain, muscle pain, back pain, and nausea. Most of these side effects of Fenovast 10mg/145mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Take Fenovast 10mg/145mg Tablet as prescribed. Your doctor will advise you on how often you take Fenovast 10mg/145mg Tablet based on your medical condition. Fenovast 10mg/145mg Tablet can be taken with or without food with a glass of water. Do not chew, crush or break the medicine.

Inform the doctor if you are allergic to any of the components in Fenovast 10mg/145mg Tablet. If you have hypothyroidism, drink more than 2 servings of alcohol per day, and have a muscle disorder (fibromyalgia), it is advised to inform your doctor before using Fenovast 10mg/145mg Tablet. Immediately contact your doctor if you experience yellowing of the skin (jaundice), allergic reaction, cramps, or muscle weakness. Consult your doctor if you are pregnant or breastfeeding.

Uses of Fenovast 10mg/145mg Tablet

Fenovast 10mg/145mg Tablet is used to manage high lipid levels and lower the risk of cardiovascular problems. The detailed uses of Fenovast 10mg/145mg Tablet are as follows:

  • High cholesterol: Fenovast 10mg/145mg Tablet reduces high levels of total cholesterol and LDL (bad cholesterol) in the blood.
  • High triglycerides: Fenovast 10mg/145mg Tablet lowers raised triglyceride levels to minimize the risk of pancreatitis and heart disease.
  • Dyslipidemia: Fenovast 10mg/145mg Tablet manages abnormal levels of cholesterol and triglycerides together.
  • Prevention of heart disease: Fenovast 10mg/145mg Tablet lowers the risk of heart attacks by managing lipid profiles.
  • Prevention of blood vessel blockage: Fenovast 10mg/145mg Tablet helps prevent atherosclerosis by reducing plaque buildup in arteries.

Directions for Use

  • It can be taken with or without food as advised by a doctor.
  • Adhere to your doctor's guidance regarding the dosage and timing of this medication for optimal effectiveness.
  • Swallow Fenovast 10mg/145mg Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • It helps lower bad cholesterol (LDL) and increases the level of good cholesterol (HDL) in dyslipidemia or hyperlipidemia. 
  • Fenovast 10mg/145mg Tablet also lowers the amount of fat or cholesterol deposition (plaque) in the arteries of the heart, thereby reducing the chance of having a heart attack or stroke in the future.
  • Balances abnormal lipid profiles by lowering triglycerides and LDL while increasing high-density lipoprotein (HDL or 'good cholesterol').
  • It increases the uptake and breakdown of LDL cholesterol in the liver. It suppresses the production of very low-density lipoprotein (VLDL), thereby reducing overall bad cholesterol levels in the blood.
  • Fenovast 10mg/145mg Tablet enhances the activity of lipoprotein lipase, an enzyme that breaks down fats in the bloodstream. It also helps reduce uric acid levels by promoting its excretion through urine.
  • It reduces the chances of complications such as heart attack, stroke, and angina (chest pain due to reduced blood flow to the heart) due to high cholesterol levels.

How Fenovast 10mg/145mg Tablet Works

Fenovast 10mg/145mg Tablet is composed of two medicines, namely: Atorvastatin and Fenofibrate. Atorvastatin is a lipid-lowering medication that blocks the enzyme HMG-CoA reductase required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Fenofibrate is another lipid-lowering agent that works by increasing the natural substance (lipoprotein lipase) that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, it decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases levels of HDL (good cholesterol).

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Fenovast 10mg/145mg Tablet

Do not take more than the prescribed dose of Fenovast 10mg/145mg Tablet as it may cause overdose. If you find symptoms like muscle pain, dark-colored urine, weakness, or yellowing of the skin, please consult a doctor immediately.

Drug Warnings

  • Do not take Fenovast 10mg/145mg Tablet if you are allergic to any of its components.
  • A patient should consult a doctor before taking Fenovast 10mg/145mg Tablet if a patient has had a previous stroke with bleeding into the brain or has small pockets of fluid in the brain from previous strokes.
  • Also, let your doctor know if you have kidney/liver problems, hypothyroidism, repeated muscle aches or pains, a family history of muscle problems, are older than 70 years, have diabetes, or have problems with certain proteins in your blood.
  • Fenovast 10mg/145mg Tablet may increase the risk of muscle problems. Talk to your doctor if you experience muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.
  • Consult your doctor before starting Fenovast 10mg/145mg Tablet if you are pregnant or breastfeeding.

Drug-Drug Interactions

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FenofibrateMipomersen
Severe

Drug-Drug Interactions

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How does the drug interact with Fenovast 10mg/145mg Tablet:
Taking Fenovast 10mg/145mg Tablet with Posaconazole can increase the blood levels of Fenovast 10mg/145mg Tablet. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Fenovast 10mg/145mg Tablet, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
FenofibrateMipomersen
Severe
How does the drug interact with Fenovast 10mg/145mg Tablet:
Mipomersen may cause liver problems and using it with Fenovast 10mg/145mg Tablet may increase that risk.

How to manage the interaction:
There may be a possibility of interaction between Fenovast 10mg/145mg Tablet and Mipomersen, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: liver damage, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, or bleeding. Do not stop using any medications without a doctor's advice.
How does the drug interact with Fenovast 10mg/145mg Tablet:
The combined use of Nicotine and Fenovast 10mg/145mg Tablet can increase the blood levels and effects of nicotine. This can increase the risk or severity of side effects.

How to manage the interaction:
Co-administration of Nicotine and Fenovast 10mg/145mg Tablet can lead to an interaction, it can be taken if advised by a doctor. If you experience any symptoms like irritation and burning sensation in the mouth and throat, increased salivation, nausea, abdominal pain, vomiting and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Fenovast 10mg/145mg Tablet:
The use of Fenovast 10mg/145mg Tablet and simvastatin can increase the risk of a rare condition called rhabdomyolysis (breakdown of skeletal muscle tissue), rhabdomyolysis can cause kidney damage. If you are elderly or have preexisting kidney disease, the risk may increase.

How to manage the interaction:
Co-administration of Fenovast 10mg/145mg Tablet and simvastatin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, fever, or dark-colored urine, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Fenovast 10mg/145mg Tablet:
Co- administration of Fenovast 10mg/145mg Tablet with Leflunomide can cause liver issues and taking it with other medications that might harm the liver, such as Fenovast 10mg/145mg Tablet, can enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Leflunomide and Fenovast 10mg/145mg Tablet, but it can be taken if prescribed by a doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Fenovast 10mg/145mg Tablet:
Co- administration of Fenovast 10mg/145mg Tablet with teriflunomide can cause liver issues and taking it with other medications that might harm the liver, such as Fenovast 10mg/145mg Tablet, can enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Teriflunomide and Fenovast 10mg/145mg Tablet, but it can be taken if prescribed by a doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Fenovast 10mg/145mg Tablet:
Taking Fenovast 10mg/145mg Tablet with Pitavastatin can increase the risk of muscle problems like liver damage and rhabdomyolysis (the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although there is a possible interaction between Pitavastatin and Fenovast 10mg/145mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience unexpected bruising or bleeding, skin rash, itching, exhaustion, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Fenovast 10mg/145mg Tablet:
Taking Warfarin together with Fenovast 10mg/145mg Tablet can increase the risk of bleeding.

How to manage the interaction:
Although taking Fenovast 10mg/145mg Tablet and Warfarin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding, bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness consult a doctor immediately. Do not stop using any medications without consulting a doctor.
FenofibrateDicoumarol
Severe
How does the drug interact with Fenovast 10mg/145mg Tablet:
co-administration of Fenovast 10mg/145mg Tablet with dicoumarol can enhance the effects of dicumarol, causing you to bleed more readily.

How to manage the interaction:
Taking Fenovast 10mg/145mg Tablet with Dicoumarol together can result in an interaction, but it can be taken if a doctor has advised it. If you notice unusual bleeding, bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these medications, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Fenovast 10mg/145mg Tablet:
Co-administration of Rosuvastatin and Fenovast 10mg/145mg Tablet can increase the blood levels of rosuvastatin and can increase the risk of liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Rosuvastatin and Fenovast 10mg/145mg Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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ATORVASTATIN-10MG+FENOFIBRATE-145MGFruit juices
Moderate

Drug-Food Interactions

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ATORVASTATIN-10MG+FENOFIBRATE-145MGFruit juices
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Blood levels of atorvastatin can rise after consuming grapefruit juice. Before quitting the drug, speak to a doctor even though there may be an interaction. Additionally, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, or yellowing of the skin or eyes, you should consult a doctor. Without first consulting your doctor, never stop taking the medication.

Diet & Lifestyle Advise

  • Eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking.
  • It is best to limit or avoid alcoholic drinks while you are taking this medicine.
  • Using this medicine with alcohol can lead to additive side effects such as increased drowsiness. Do not drive or operate machinery if you are drinking alcohol-containing beverages.
  • If you notice slurred speech, confusion, severe weakness or difficulty breathing, contact your health care provider immediately.
  • Try aromatherapy, yoga, and meditation to help relax your body and mind.
  • Try to do breathing exercises to get more oxygen.
  • Eat a healthy diet especially rich in soluble fibers like beans, legumes, whole grains, flax, apples, and citrus fruits.
  • Try to replace most of your saturated fats with unsaturated fats that can reduce total cholesterol and LDL cholesterol in a short period. Foods like avocados, olive oil, fatty fish, and nuts contain lots of heart-healthy unsaturated fats, so it’s beneficial to eat them regularly.
  • Try to adopt a Mediterranean-style diet rich in olive oil, fruits, vegetables, nuts, whole grains, and fish, and lower the consumption of red meat.
  • Try to give priority to more fruits and veggies in your daily meal as these contain antioxidants that help to lower LDL.

Habit Forming

No

Therapeutic Class

ANTILIPEMICS
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Alcohol

Unsafe

Avoid drinking alcohol with Fenovast 10mg/145mg Tablet. It can raise triglyceride levels and may increase your risk of liver damage.

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Pregnancy

Unsafe

Fenovast 10mg/145mg Tablet contains Atorvastatin, a pregnancy category X medicine that can harm both the pregnant mother and the unborn baby (fetus). So, please consult your doctor if you are pregnant.

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Breast Feeding

Consult your doctor

Fenovast 10mg/145mg Tablet is known to pass into the breast milk and can affect the baby's health. So, please consult your doctor if you are breastfeeding.

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Driving

Safe if prescribed

Fenovast 10mg/145mg Tablet does not usually affect your ability to drive.

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Liver

Caution

Fenovast 10mg/145mg Tablet to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Fenovast 10mg/145mg Tablet to be taken with caution, especially if you have a history of kidney disease or are currently on dialysis. The dose may have to be adjusted by your doctor.

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Children

Caution

Not recommended in children as the safety and efficiency of Fenovast 10mg/145mg Tablet has not been established in children.

Have a query?

FAQs

Fenovast 10mg/145mg Tablet is used to treat high lipid levels and reduce the risk of heart diseases. It helps in lowering the bad cholesterol (LDL) and increases the level of good cholesterol (HDL).

Strictly no, a patient is advised to take proper healthy diet free of oily and fatty products recommended by doctor for the best results of this medication.

As such, no harmful interaction has been reported, yet doctor consultation is advised.

This drug is primarily used to lower high levels of fatty acids in blood & to use it for weight loss is only done on a doctor's recommendation after he/she thoroughly checks the state of the patient.

Certain antibiotics like erythromycin and clarithromycin interact with Fenovast 10mg/145mg Tablet and hence should not be used simultaneously with Fenovast 10mg/145mg Tablet unless consulted & recommended by a doctor.

Fenovast 10mg/145mg Tablet may cause side effects like hyperglycemia (high blood sugar), headache, blurred vision, stomach pain, constipation, headaches, joint swelling (oedema), joint pain, muscle pain, back pain, slow heart rate, and nausea. If the side effects are persistent, reach out to your doctor.

Liver damage is a very rare side effect of Fenovast 10mg/145mg Tablet. Consult the doctor if you notice signs of liver problems like yellowing of skin and eyes, itchy skin, or dark urine.

Fenovast 10mg/145mg Tablet can cause muscle pain as a side effect. Consult the doctor if you have muscle pain, muscle spasms/cramps or muscle weakness.

Follow a healthy diet and exercise regularly. Avoid smoking and alcohol consumption. Manage stress by doing meditation.

Consult the doctor before taking Fenovast 10mg/145mg Tablet with other medicines like anticoagulants, anti-gout medicines, antibiotics, antifungals, anti-viral medicines, contraceptive pills, anti-arthritis pills and other fibrates.

Country of origin

India
Other Info - FE49329

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