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compositionComposition:FLUTICASONE FUROATE-27.5MCG+OXYMETAZOLINE-50MCG
prescriptionPrescription Medicine
F2Nase-OX Nasal Spray 70 MDI

F2Nase-OX Nasal Spray 70 MDI is used to treat Perennial allergic rhinitis (year-round nasal allergy). It helps relieve symptoms such as sneezing, a runny nose, nasal blockage, itching, and watery eyes. It reduces nasal swelling and congestion, thereby facilitating breathing.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

FLUTICASONE FUROATE-27.5MCG+OXYMETAZOLINE-50MCG

Manufacturer/Marketer :

Neomedix Healthcare India Pvt Ltd

Consume Type :

Nasal

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About F2Nase-OX Nasal Spray 70 MDI

F2Nase-OX Nasal Spray 70 MDI is used to treat perennial allergic rhinitis (year-round nasal allergy). Perennial allergic rhinitis is an inflammatory condition that can last for hours or for several days throughout the year. Symptoms may include sneezing, runny nose, congestion, stuffy nose or watery eyes.

F2Nase-OX Nasal Spray 70 MDI contains fluticasone furoate and oxymetazoline, which work together to relieve nasal allergy symptoms. It helps reduce nasal swelling and congestion. This improves airflow and makes breathing more comfortable. Overall, it helps control symptoms of allergic rhinitis and supports daily comfort.

F2Nase-OX Nasal Spray 70 MDI should be used as advised by your doctor. This medicine may cause common side effects, such as headache, changes in taste, or nosebleeds. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Avoid using F2Nase-OX Nasal Spray 70 MDI if you are allergic to it or any other components in it. If you have diabetes, high blood pressure, hyperthyroidism, or heart disease, inform your doctor before using F2Nase-OX Nasal Spray 70 MDI. If you are pregnant or breastfeeding, inform your doctor before using F2Nase-OX Nasal Spray 70 MDI. This medication is not recommended for children under 6 years of age.

Uses of F2Nase-OX Nasal Spray 70 MDI

F2Nase-OX Nasal Spray 70 MDI is used in the treatment of perennial allergic rhinitis (year-round nasal allergy). The detailed uses of F2Nase-OX Nasal Spray 70 MDI are as follows:

  • Relieves nasal allergy symptoms: F2Nase-OX Nasal Spray 70 MDI helps reduce sneezing, runny nose, nasal congestion, and itching.

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Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Close one nostril and insert the tip of the bottle into the other nostril. Now spray the liquid towards the sides of the nostrils while keeping your head straight and breathing gently. Repeat the same process for another nostril if needed.
  • Wipe the nozzle of the spray bottle with a clean tissue or cloth.
  • Do not share your nasal spray with others to avoid infections.

Key Benefits

  • Helps relieve sneezing, runny nose, nasal itching, and congestion.
  • Reduces swelling and irritation in the nasal passages.
  • Improves airflow and makes breathing easier.
  • Helps reduce watery eyes and nasal discomfort.
  • Supports better sleep and daily comfort

How F2Nase-OX Nasal Spray 70 MDI Works

F2Nase-OX Nasal Spray 70 MDI is a combination of Fluticasone furoate (corticosteroid) and Oxymetazoline (decongestant). • Fluticasone furoate inhibits the release of certain chemicals in the body that cause inflammatory reactions. • Oxymetazoline contracts and narrows the blood vessels in the linings of the nasal passages. • Together, F2Nase-OX Nasal Spray 70 MDI provides relief from allergic rhinitis.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of F2Nase-OX Nasal Spray 70 MDI

Overdosing is unlikely to be harmful, although it is best not to exceed the prescribed amount. Seek emergency medical attention or call your doctor if you notice any unusual symptoms, or if anyone has accidentally swallowed the medication or if you suspect that you may have overdosed on F2Nase-OX Nasal Spray 70 MDI.

Drug Warnings

  • F2Nase-OX Nasal Spray 70 MDI should be avoided if you are allergic to any of the medicines.
  • If you have diabetes, high blood pressure, hyperthyroidism, or heart disease, inform your doctor before using F2Nase-OX Nasal Spray 70 MDI. If you are pregnant or breastfeeding, tell your doctor before using F2Nase-OX Nasal Spray 70 MDI.
  • Avoid taking F2Nase-OX Nasal Spray 70 MDI if you have narrow-angle glaucoma or if you have undergone recent trans-nasal surgery. You are recommended to remove nasal fluids before applying F2Nase-OX Nasal Spray 70 MDI by blowing the nose.
  • Avoid sharing F2Nase-OX Nasal Spray 70 MDI with other people to prevent the spread of infection.
  • F2Nase-OX Nasal Spray 70 MDI is not recommended for children below six years of age.
  • It is recommended to avoid smoking and alcohol consumption, as they may increase adverse effects.

Drug-Drug Interactions

verifiedApollotooltip
Fluticasone furoateMifepristone
Critical
Fluticasone furoateDesmopressin
Critical

Drug-Drug Interactions

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Fluticasone furoateMifepristone
Critical
How does the drug interact with F2Nase-OX Nasal Spray 70 MDI:
Using F2Nase-OX Nasal Spray 70 MDI with Mifepristone can reduce the effect of F2Nase-OX Nasal Spray 70 MDI.

How to manage the interaction:
Taking F2Nase-OX Nasal Spray 70 MDI with Mifepristone is not recommended, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
Fluticasone furoateDesmopressin
Critical
How does the drug interact with F2Nase-OX Nasal Spray 70 MDI:
Co-administration of desmopressin together with fluticasone may increase the risk of hyponatremia, a condition associated with low levels of salt in the blood.

How to manage the interaction:
If you have to use Desmopressin and Fluticasone together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact your doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
OxymetazolineDihydroergotamine
Critical
How does the drug interact with F2Nase-OX Nasal Spray 70 MDI:
Using dihydroergotamine together with F2Nase-OX Nasal Spray 70 MDI may significantly increase blood pressure.

How to manage the interaction:
Taking F2Nase-OX Nasal Spray 70 MDI with Dihydroergotamine can cause an interaction, consult a doctor before taking it. You should seek immediate medical attention if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discolouration of fingers or toes, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion, or slurred speech. Do not stop using any medications without consulting a doctor.
Fluticasone furoateCladribine
Severe
How does the drug interact with F2Nase-OX Nasal Spray 70 MDI:
Combining Cladribine with F2Nase-OX Nasal Spray 70 MDI can increase the risk of developing serious infections.

How to manage the interaction:
Although taking F2Nase-OX Nasal Spray 70 MDI and Cladribine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, or pain during urine consult a doctor right away. Do not stop using any medications without talking to a doctor.
Fluticasone furoateVoriconazole
Severe
How does the drug interact with F2Nase-OX Nasal Spray 70 MDI:
Taking F2Nase-OX Nasal Spray 70 MDI with Voriconazole may increase the absorption of F2Nase-OX Nasal Spray 70 MDI into the bloodstream and increase the risk of side effects.

How to manage the interaction:
Although F2Nase-OX Nasal Spray 70 MDI and Voriconazole can cause an interaction, but can be taken together if advised by a doctor. However, if you experience swelling, muscle weakness, excessive growth of facial or body hair contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Fluticasone furoateKetoconazole
Severe
How does the drug interact with F2Nase-OX Nasal Spray 70 MDI:
Using Ketoconazole and F2Nase-OX Nasal Spray 70 MDI may significantly increase the absorption of fluticasone into the blood stream.

How to manage the interaction:
Although taking Ketoconazole and F2Nase-OX Nasal Spray 70 MDI together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist consult a doctor. Without consulting a doctor, never stop taking any drugs.
Fluticasone furoateTroleandomycin
Severe
How does the drug interact with F2Nase-OX Nasal Spray 70 MDI:
Troleandomycin may significantly increase the absorption of fluticasone into the blood stream.

How to manage the interaction:
Although there is a possible interaction between F2Nase-OX Nasal Spray 70 MDI and Troleandomycin, but can be taken together if advised by a doctor. However, if you experience weight gain, high blood pressure, swelling, high blood sugar, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Fluticasone furoateTelaprevir
Severe
How does the drug interact with F2Nase-OX Nasal Spray 70 MDI:
When F2Nase-OX Nasal Spray 70 MDI is taken with telaprevir, the amount of F2Nase-OX Nasal Spray 70 MDI in the blood may increase.

How to manage the interaction:
There may be a possibility of interaction between F2Nase-OX Nasal Spray 70 MDI and Telaprevir, but can be taken together if advised by a doctor. However, if you experience weight gain, high blood pressure, swelling, high blood sugar, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Fluticasone furoateAtazanavir
Severe
How does the drug interact with F2Nase-OX Nasal Spray 70 MDI:
When F2Nase-OX Nasal Spray 70 MDI is taken with Atazanavir, the amount of F2Nase-OX Nasal Spray 70 MDI in the blood can increases

How to manage the interaction:
Co-administration of F2Nase-OX Nasal Spray 70 MDI with Atazanavir can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience swelling, weight gain, high blood sugar, weak muscles, acne, thin skin, easy bruising, irregular periods, too much facial or body hair, bruises, infections, or asthma attacks contact your your doctor right away. Do not discontinue any medications without consulting your doctor.
Fluticasone furoatePosaconazole
Severe
How does the drug interact with F2Nase-OX Nasal Spray 70 MDI:
Taking F2Nase-OX Nasal Spray 70 MDI with posaconazole can increase the levels of F2Nase-OX Nasal Spray 70 MDI in the blood.

How to manage the interaction:
Although there is an interaction between F2Nase-OX Nasal Spray 70 MDI and posaconazole, they can be taken together if prescribed by a doctor. However, if you experience muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Allergen Avoidance:

  • Avoid triggers such as dust, pollen, smoke, and strong odours.
  • Keep windows closed during high pollen seasons.

Fluids & Humidity:

  • Drink plenty of fluids to keep nasal passages moist.
  • Use a humidifier if the air is dry to reduce nasal dryness.

Habits:

  • Avoid smoking and second-hand smoke, as they irritate the nasal lining.
  • Do not use other nasal sprays unless advised by your doctor.

Hygiene:

  • Wash your hands regularly and maintain a clean environment to reduce the risk of infection.

Nasal Care:

  • Use the nasal spray exactly as prescribed and avoid overuse to prevent rebound congestion.
  • Gently blow your nose before using the spray for a better effect.

Habit Forming

No

Therapeutic Class

[DECONGESTANTS, ANTIALLERGIC]

All Substitutes & Brand Comparisons

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Alcohol

Unsafe

Avoid consumption of alcohol with F2Nase-OX Nasal Spray 70 MDI as it may increase adverse effects. Please consult a doctor before consuming alcohol with F2Nase-OX Nasal Spray 70 MDI.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before using F2Nase-OX Nasal Spray 70 MDI. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before starting treatment with F2Nase-OX Nasal Spray 70 MDI. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

F2Nase-OX Nasal Spray 70 MDI may cause drowsiness in some people. Therefore, drive only if you are alert after using F2Nase-OX Nasal Spray 70 MDI.

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Liver

Caution

F2Nase-OX Nasal Spray 70 MDI should be used with caution in patients with liver disease. Let your doctor know if you have any history of liver disease. Your doctor will weigh the benefits and potential risks before prescribing F2Nase-OX Nasal Spray 70 MDI.

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Kidney

Caution

F2Nase-OX Nasal Spray 70 MDI should be used with caution in patients with kidney disease. Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing F2Nase-OX Nasal Spray 70 MDI.

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Children

Caution

F2Nase-OX Nasal Spray 70 MDI is not recommended for children under 6 years, as its safety and effectiveness have not been established.

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Heart

Caution

F2Nase-OX Nasal Spray 70 MDI should be used cautiously in patients with heart problems. Oxymetazoline may constrict blood vessels and increase blood pressure; therefore, medical supervision is essential before use.

bannner image

Geriatrics

Caution

F2Nase-OX Nasal Spray 70 MDI may be used in geriatric patients, but only with medical guidance. Age-related sensitivity and potential for elevated blood pressure require cautious use and monitoring.

FAQs

F2Nase-OX Nasal Spray 70 MDI is used to treat perennial allergic rhinitis, a condition that occurs when the immune system reacts to a foreign substance.

F2Nase-OX Nasal Spray 70 MDI is a combination of Fluticasone furoate (corticosteroid) and Oxymetazoline (decongestant). Fluticasone furoate inhibits the release of inflammatory mediators that drive inflammatory reactions. On the other hand, oxymetazoline constricts and narrows the blood vessels in the linings of the nasal passages. Thus, it helps relieve allergic symptoms such as sneezing, runny nose, watery eyes, itching, swelling, and congestion or stiffness.

No, F2Nase-OX Nasal Spray 70 MDI is not recommended for use if you have had a recent nose operation or any nose infections, as it may cause nose bleeding and excessive nasal pain, further worsening your condition. Consult your physician and follow instructions for the best results.

People who are allergic to any of the ingredients in F2Nase-OX Nasal Spray 70 MDI should avoid using it. Additionally, individuals with narrow-angle glaucoma (a condition where the angle between the iris and cornea is too narrow) or those who have recently undergone trans-nasal surgery should avoid using it. Children under six years of age should not use this medication. Consult your doctor before using F2Nase-OX Nasal Spray 70 MDI, especially if you have any existing health conditions such as diabetes, high blood pressure, overactive thyroid, or heart disease.

F2Nase-OX Nasal Spray 70 MDI may cause side effects in some individuals, such as headaches, changes in taste, or nosebleeds. These side effects are typically mild and tend to improve or resolve without medical intervention. However, if the side effects worsen or do not resolve after a few days, please consult your physician for advice.

If you are pregnant or planning to become pregnant, inform your doctor before using F2Nase-OX Nasal Spray 70 MDI. While there is limited information on the safety of this medication during pregnancy, your doctor may prescribe it if the benefits outweigh the risks.

F2Nase-OX Nasal Spray 70 MDI is not recommended for children under six years old, as its safety and effectiveness have not been established for this age group.

If you accidentally take an overdose of F2Nase-OX Nasal Spray 70 MDI, there’s no need to panic, as it does not cause life-threatening effects. However, it is important to contact your doctor or seek medical advice as soon as possible if you experience any symptoms, such as increased nasal irritation, headache, dizziness, difficulty breathing, nose damage, or blurred or cloudy vision.

Country of origin

India

Manufacturer/Marketer address

Plot No. -13 , Sector -5, Industrial Area, Parwanoo, Distt. Solan (H.P) India
Other Info - F2N0003

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Feb 10, 2026 | 9:25 AM IST

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