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compositionComposition:AFLIBERCEPT-40MG
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Prescription Medicine
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₹49540 with coupons & bank offers*

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Eylea 40mg/ml Injection is an anti-angiogenic ophthalmic agent used to treat wet age-related macular degeneration, macular oedema, diabetic macular oedema, diabetic retinopathy, and retinopathy of prematurity. It contains Aflibercept, a vascular endothelial growth factor-A (VEGF-A) and placental growth factor (PlGF) antagonist. It works by stopping abnormal blood vessel growth and leakage in the eyes that may cause vision loss in people with eye conditions. It helps stabilise and improve vision loss.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
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More about the Product

Composition :

AFLIBERCEPT-40MG

Manufacturer/Marketer :

Bayer Zydus Pharma Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Eylea 40mg/ml Injection

Eylea 40mg/ml Injection is a specialised prescription medication injected into the eye to treat retinal conditions that cause vision loss. It is primarily used to manage diseases like wet age-related macular degeneration, diabetic macular edema, and retinal swelling. By targeting the source of fluid leakage in the eye, this medicine helps prevent further decline in visual clarity.

Because this medication is injected directly into the eye by a specialist, it does not have any direct interactions with food or drink. It is given at regular intervals, and keeping your appointments consistent is essential for protecting your sight. Incorporating specific lifestyle changes, such as eating a nutrient-dense diet and protecting your eyes from sun exposure, can further support your treatment outcomes.

While the treatment is generally well-tolerated, some patients may experience mild side effects like temporary eye discomfort or small red spots on the white of the eye. However, you must contact your eye doctor immediately if you experience sudden vision changes, severe eye pain, or signs of an eye infection. Monitoring your symptoms closely after each session is a key part of staying safe.

Before starting treatment with Eylea 40mg/ml Injection, tell your eye specialist about your full medical history. Do not receive Eylea 40mg/ml Injection if you have an active infection in or around the eye (ocular or periocular infection), severe eye inflammation, or if you are allergic to Eylea 40mg/ml Injection or any of the ingredients in this medicine. Your doctor will assess whether your eyes are healthy enough to receive the injection safely.

This medicine does not typically interact with oral drugs, but it is important to discuss all other eye drops you are using with your doctor. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your specialist to understand the risks and benefits of this treatment.

Uses of Eylea 40mg/ml Injection

Your doctor may prescribe Eylea 40mg/ml Injection to treat the following conditions to help reduce retinal swelling, prevent vision loss, and preserve eyesight:

  • Wet Age-Related Macular Degeneration (AMD): Eylea 40mg/ml Injection helps slow down the growth of fragile, abnormal blood vessels in the retina, reducing fluid leakage and helping to preserve central vision.
  • Diabetic Macular Edema (DME): This medicine reduces swelling in the center of the retina caused by leaky blood vessels in people with diabetes, which helps improve visual sharpness.
  • Diabetic Retinopathy: Eylea 40mg/ml Injection helps manage diabetic eye damage by preventing the growth of abnormal blood vessels that can bleed and cause severe vision loss.
  • Macular Edema Following Retinal Vein Occlusion (RVO): It targets and relieves swelling in the retina caused by blocked blood vessels, restoring lost clarity of vision.

Key Benefits

Using Eylea 40mg/ml Injection as prescribed helps protect your vision, reduce retinal swelling, and slow the progression of retinal disease. Here are the key benefits you can expect:

  • Helps preserve and improve vision: Slows the progression of retinal disease and, in many cases, helps stabilise or improve vision, reducing the risk of permanent vision loss.
  • Reduces retinal swelling: Helps decrease fluid buildup and swelling in the retina, improving visual clarity and reducing blurred vision.
  • Supports everyday independence: By improving and preserving vision, it helps many people continue daily activities such as reading, recognising faces, and driving more safely, where appropriate.
Side effects of Eylea 40mg/ml Injection
  • To the affected part, apply warm compresses to get a temporary relief.
  • Rinse your eye carefully with clean water and try to blow any dust particle that could have entered.
  • Take over the counter medication to lubricate your eye or if there is pain due to allergy to soothe the eye.
  • If there is persistent pain in your eye, consult your doctor and follow the medication immediately.
  • Eating foods high in vitamins C (like oranges, peppers, and tomatoes) and E (like peanuts, spinach, and broccoli) may help protect your eyes from cataracts or slow them down.
  • Quit smoking and cut back on alcohol.
  • Wear sunglasses when you are outside to protect your eyes from the sun.
  • Keep your blood sugar under control, because high blood sugar can cause changes in the eye lens that lead to cataracts.
  • Have regular eye checkups to catch any problems early.
  • Maintain a balanced diet with leafy greens, carrots, and citrus fruits.
  • Ensure you drink enough water throughout the day to stay hydrated.
  • Protect your eyes by wearing sunglasses and protective eyewear when necessary.
  • Rest your eyes by blinking often and taking regular breaks from screens to reduce strain.
  • Quit smoking to minimize eye damage and improve overall eye health significantly.
  • Consult an eye doctor if you notice a sudden increase or worsening of floaters.
  • Eat a balanced diet rich in omega-3 fatty acids, vitamins A and C, and antioxidants to support eye health.
  • Include foods high in antioxidants, such as leafy greens, berries, and nuts.
  • Wear protective eyewear during activities that may pose a risk to your eyes.
  • Refrain from touching or rubbing your eyes to minimize potential irritation and prevent exacerbating the condition.
  • Maintain good hygiene and clean your contact lenses properly (if applicable).
  • Get regular eye exams to monitor the condition and adjust treatment as needed.
  • Manage underlying conditions, such as glaucoma or diabetes, to reduce the risk of corneal edema.
  • Eat a healthy, low-fat diet rich in whole grains, fruits, and vegetables.
  • Drink plenty of water to stay hydrated.
  • Get adequate sleep and avoid direct sunlight.
  • Follow a low-salt diet to minimize fluid retention.
  • Apply a cold compress to reduce inflammation and soothe affected areas.
  • Place a clean gauze pad immediately at the bleeding site and apply direct, firm pressure for several minutes.
  • Raise the affected area above the heart level if possible to decrease blood flow.
  • If the bleeding at the injection site is excessive, does not stop with pressure or is accompanied by other symptoms like pain, redness or swelling, contact your doctor immediately.
  • Apply a cold compress to the affected area after bleeding has stopped to reduce swelling.
  • Rotate the injection site for medicines that require frequent injections to reduce tissue damage and bleeding.

Directions for Use

  • Eylea 40mg/ml Injection will be administered by a healthcare professional.
  • Do not self-administer it.

How Eylea 40mg/ml Injection Works

Eylea 40mg/ml Injection contains aflibercept, an anti-VEGF medicine that blocks vascular endothelial growth factor (VEGF), a protein responsible for the growth of abnormal blood vessels in the retina. In certain retinal diseases, excess VEGF causes fragile blood vessels to grow and leak fluid or blood, leading to retinal swelling and vision loss. When injected into the eye, Eylea 40mg/ml Injection binds to VEGF and prevents it from activating its receptors. This blocks the growth of abnormal blood vessels, reduces fluid leakage, and helps decrease retinal swelling. As a result, it helps preserve vision, improve visual clarity, and slow the progression of retinal disease.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Eylea 40mg/ml Injection. Please consult the doctor.

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Pregnancy

Caution

Aflibercept belongs to pregnancy category C. Eylea 40mg/ml Injection should be used during pregnancy only if the benefits outweigh the risks. Women of reproductive potential must use effective birth control pills to avoid pregnancy.

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Breast Feeding

Caution

Small amounts of the medicine may pass into breast milk. Your doctor will decide whether to discontinue nursing or the medicine, taking into account the importance of the medicine to the mother.

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Driving

Unsafe

Eylea 40mg/ml Injection may cause temporary vision disturbances. Avoid driving or operating heavy machinery if you experience this.

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Liver

Consult your doctor

If you have a history of liver problems, inform the doctor before receiving Eylea 40mg/ml Injection.

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Kidney

Consult your doctor

If you have a history of kidney problems, inform the doctor before receiving Eylea 40mg/ml Injection.

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Children

Caution

The safety and effectiveness of Eylea 40mg/ml Injection in children have not been established except for retinopathy of prematurity. However, please consult the paediatrician if you have any concerns.

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Heart

Safe if prescribed

Eylea 40mg/ml Injection is generally safe for heart patients when used only under medical supervision. However, it is important to consult your doctor if you have any concerns or underlying conditions.

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Geriatrics

Safe if prescribed

Eylea 40mg/ml Injection is generally considered safe for use in geriatric patients; however, significant precautions should be taken due to age-related sensitivities.

What if I have taken an overdose of Eylea 40mg/ml Injection

Because this medication is administered by a trained eye specialist in a controlled clinical setting, receiving an accidental overdose is highly unlikely. If you experience severe eye pressure or pain after an injection, contact your ophthalmologist right away.

Diet & Lifestyle Advise

  • Eat antioxidant-rich foods: Include foods rich in lutein and zeaxanthin, such as spinach, kale, and other leafy green vegetables, to help support retinal health.
  • Include omega-3 fatty acids: Eat foods such as salmon, walnuts, and flaxseeds to support the health of the blood vessels in your eyes.
  • Avoid smoking: Quit smoking, as it can accelerate retinal damage and increase the progression of macular degeneration.
  • Maintain overall health: Keep your blood pressure, cholesterol, and blood sugar levels under control, as they can affect the health of your retinal blood vessels.
  • Protect your eyes: Wear sunglasses that block 100% of UVA and UVB rays when outdoors to help protect your eyes from harmful sunlight.

Health Queries

I am suffering from Type 1 diabetes and have developed diabetic retinopathy and diabetic neuropathy. What medications or pharmaceutical treatment options are available to manage these complications?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Managing these complications starts with keeping your blood sugar stable using insulin. For diabetic retinopathy, treatments include eye injections of anti-VEGF medications (such as aflibercept or ranibizumab) or corticosteroids to reduce swelling and protect your vision. For diabetic neuropathy, nerve pain can be effectively managed with medications like gabapentinoids (pregabalin or gabapentin), SNRIs (duloxetine), or tricyclic antidepressants (amitriptyline). Additionally, managing your blood pressure and cholesterol is vital for protecting both your eyes and nerves. Please consult your specialist to find the safest and most effective treatment plan tailored specifically for you.

Is surgery necessary in the early stages of age-related macular degeneration, or can it be managed with medicines alone?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

In the early stages of age-related macular degeneration, surgery is usually not needed. Most people with early disease have only mild retinal changes and may not notice much vision loss, so the condition is managed with simple measures rather than surgery. Doctors often recommend lifestyle changes such as eating a healthy diet rich in green leafy vegetables, fruits, and fish, and stopping smoking if applicable. Special vitamin supplements containing antioxidants and zinc may also help slow down progression in some patients. Regular eye check-ups are important to monitor any changes over time. Injectable eye medicines, such as ranibizumab or aflibercept, are mainly used in the later stage of wet macular degeneration, in which abnormal blood vessels grow and affect vision. Surgical treatment has a limited role and is rarely used for this condition. Overall, early detection, healthy habits, and regular follow-up with an eye doctor are the most effective ways to manage the condition in its early stages.

I have age-related macular degeneration in my left eye and received a Lucentis injection five years ago. Currently, I do not have any major problems. As this condition is age-related, I am concerned that it may worsen in the future. What treatments and precautions should I follow to prevent it from progressing?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

Age-related macular degeneration is a long-term eye condition that can progress slowly over time. It is a good sign that you have remained stable since your Lucentis injection (Ranibizumab), but regular follow-up with an eye doctor is very important to detect early changes. Treatment depends on the type and stage of the condition. If it becomes active again, ranibizumab or other similar medicines, such as aflibercept, may be needed to control abnormal blood vessel growth and protect vision. For early or dry stages, specific eye vitamins containing antioxidants and zinc may help slow progression in some patients, if advised by your doctor. You can take simple precautions to protect your eyesight, such as avoiding smoking, eating a healthy diet rich in green leafy vegetables, fruits, and fish, and wearing sunglasses to protect against strong sunlight. Keep your blood pressure, blood sugar, and cholesterol under good control, and monitor your vision at home. If you notice any distortion or blurred patches, please see your eye doctor promptly.
health query

Have a query?

How Soon It Starts Working

The time required for Eylea 40mg/ml Injection to start to work: The time required for Eylea 40mg/ml Injection to show its action is not clinically established. The time for which the effects of Eylea 40mg/ml Injection last: The duration of action for Eylea 40mg/ml Injection is not clinically established.

What if you forget to take Eylea 40mg/ml Injection

If you miss an appointment for your injection, contact your eye clinic immediately to reschedule. Keeping your appointments on track is vital to prevent your eye condition from worsening.

Storage

• Eylea 40mg/ml Injection is usually stored and handled by healthcare professionals.• Keep it refrigerated at 2°C to 8°C (36°F to 46°F) in its original carton.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Avoid touching your eye: Do not rub or touch the treated eye for at least a few days after the injection to reduce the risk of injury or infection.
  • Use caution after treatment: Avoid driving or operating machinery immediately after your appointment, as your vision may be temporarily blurred due to the injection or dilating eye drops.
  • Monitor your eye: Check the treated eye daily for severe redness, swelling, pain, discharge, or worsening vision, and contact your doctor immediately if these occur.
  • Use other eye drops correctly: If you use other eye drops, wait at least 5–10 minutes between applications or follow your doctor's instructions.
  • Inform your doctor about procedures: Tell your ophthalmologist if you have any upcoming surgeries or dental procedures scheduled.

Drug-Drug Interactions

verifiedApollotooltip
  • Other ophthalmic medications: Using other eye drops or eye treatments at the same time may interfere with Eylea 40mg/ml Injection. Talk to your doctor before combining treatments.
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Eylea 40mg/ml Injection when used as directed. 
 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[OPHTHALMOLOGIC AGENTS]

FAQs

Eylea 40mg/ml Injection is used to treat Wet age-related macular degeneration, Macular oedema after retinal vein occlusion, Diabetic macular oedema, Diabetic retinopathy, and Retinopathy of prematurity.
Eylea 40mg/ml Injection works by stopping abnormal blood vessel growth and leakage in the eyes that may cause vision loss in people with eye conditions.
In some patients, Eylea 40mg/ml Injection may cause intraocular pressure (an increase in eye pressure) after administering Eylea 40mg/ml Injection. Hence, your doctor will monitor this condition after each administration.
Limited data is available regarding the safety of Eylea 40mg/ml Injection in patients who have had a stroke, mini-stroke, or heart attack. Inform your doctor if you have had a stroke or heart attack. Your doctor will administer Eylea 40mg/ml Injection with caution.
Your eye will be numbed with special drops before the procedure, so most patients feel only a slight pressure or a brief pinch. Talk to your doctor if you are anxious about the injection.
No, you should arrange for someone to drive you home because your pupils may be dilated and your vision will be temporarily blurry. Talk to your doctor about when it is safe to drive again.
A small, harmless red spot from a broken blood vessel is common, but severe or worsening redness can be a sign of infection. Talk to your doctor immediately if the redness is accompanied by pain.
This medicine is designed to manage chronic retinal conditions and prevent vision loss, but it is not a permanent cure. Talk to your doctor about what results you can realistically expect.
There is limited research on the effects of this medicine during pregnancy, so it is generally not recommended unless absolutely necessary. Talk to your doctor to weigh the risks and benefits.
You should avoid swimming, heavy lifting, and rubbing your eye for a few days to prevent infection and strain. Talk to your doctor for a complete list of post-treatment precautions.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

Bayer House, Central Avenue, Hiranandani Estate, Thane (west) Thane 400607 India
Other Info - EYL0002
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