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EXPAVON INFUSION belongs to the group of medications called plasma volume expanders. It is used to treat hypovolemia (low blood volume). It draws water into the bloodstream, increasing plasma volume and improving circulation. It helps replace lost blood volume, improving blood flow and pressure. It supports vital organ function and stability during operations or injury, reducing the risk of shock and fluid loss. The common side effects of EXPAVON INFUSION may include itching, reduced plasma proteins, decreased hematocrit, and increased serum amylase.

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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About EXPAVON INFUSION

EXPAVON INFUSION is a sterile liquid solution injected into a vein to treat and prevent low blood volume, a condition known as hypovolemia. This medicine is typically given in hospital settings when a person has lost a significant amount of blood due to surgery, trauma, or injury, and other standard fluids are not sufficient.

Because this medicine is given directly into a vein during acute medical situations, it does not have a regular daily schedule, and food intake does not affect how it works. While you are recovering, your healthcare team will monitor your fluid balance and may suggest specific dietary adjustments, like eating iron-rich foods, to help your body rebuild its blood supply.

While receiving this injection, some people may experience side effects such as itching, skin flushing, or mild allergic reactions. It is critical to tell your doctor or nurse immediately if you notice severe itching, breathing difficulties, or a sudden decrease in how much you urinate, as these can point to more serious issues.

Do not use this if you have been diagnosed with severe kidney damage, are critically ill (such as having a severe blood infection or sepsis), or have severe heart failure. Tell your doctor if you have a history of bleeding disorders or liver damage before this medicine is given to you.

This injection can interact with other intravenous fluids, blood-thinning medications, and drugs that affect your kidneys. If you are pregnant, breastfeeding, or are an older adult, discuss your health history thoroughly with your doctor, as this medicine is only used in these groups when the benefits clearly outweigh the risks.

Uses of EXPAVON INFUSION

EXPAVON INFUSION is an intravenous colloid solution that increases the volume of fluid within the bloodstream. Its use is limited to specific clinical situations and depends on the patient's condition and local treatment guidelines:

  • Hypovolaemia: May be used for short-term intravascular volume replacement in selected patients with hypovolaemia when appropriate alternatives are considered unsuitable.
  • Circulatory volume support: Helps temporarily increase the volume of fluid circulating within the blood vessels, which may support blood pressure and circulation when there is significant fluid loss.

Key Benefits

When clinically appropriate, EXPAVON INFUSION provides temporary intravascular volume expansion to support circulation during acute fluid loss:

  • Rapid volume expansion: Increases the volume of fluid within the blood vessels, providing short-term circulatory support.
  • Supports blood pressure: By increasing intravascular volume, it may help support blood pressure in selected patients with hypovolaemia.
  • Supports tissue perfusion: Improving circulating volume can help maintain blood flow to vital organs when reduced blood volume is contributing to impaired circulation.
  • Useful in selected acute-care settings: May be considered during certain emergency or peri-operative situations when volume replacement is required and the treating team determines that its benefits outweigh its risks.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • EXPAVON INFUSION should be administered by a nurse or doctor to ensure proper dosage, technique, and monitoring for any potential side effects or complications.
  • Do not self-administer.

How EXPAVON INFUSION Works

EXPAVON INFUSION contains hydroxyethyl starch, a colloid plasma volume expander that helps restore and maintain blood volume. EXPAVON INFUSION consists of large molecules that remain within the bloodstream after being injected. These molecules exert an osmotic effect that helps draw fluid into the blood vessels and retain it within the circulation. This increases the volume of blood circulating through the body, helping improve blood pressure and blood flow. By expanding the circulating blood volume, EXPAVON INFUSION helps restore adequate circulation when there has been significant fluid or blood volume loss. Together, these actions help increase circulating blood volume, improve blood pressure and support blood flow to vital organs and tissues.
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Alcohol

Consult your doctor

It is unknown whether alcohol interacts with EXPAVON INFUSION . However, avoid alcohol consumption while treatment with EXPAVON INFUSION as a precautionary measure to prevent unpleasant side effects.

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Pregnancy

Consult your doctor

There are no adequate and well-controlled studies in pregnant women. Please, inform your doctor before using this medication during pregnancy.

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Breast Feeding

Consult your doctor

It is unknown whether EXPAVON INFUSION passes into breastmilk. Please consult your doctor if you are breastfeeding to evaluate the potential risks and benefits.

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Driving

Consult your doctor

EXPAVON INFUSION is not known to cause dizziness. However, please consult your doctor if you experience dizziness for further evaluation and guidance.

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Liver

Caution

EXPAVON INFUSION is not recommended in patients with severe liver diseases. Please consult your doctor if you have any concerns.

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Kidney

Caution

EXPAVON INFUSION is not recommended in patients with renal impairment experiencing oliguria or anuria unless caused by hypovolemia. Please consult your doctor if you have any concerns.

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Children

Caution

There is limited information on its use in children, and it should only be administered under close medical supervision. Dosage will be individualized, especially for newborns and premature infants. Please consult the doctor for guidance.

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Heart

Caution

EXPAVON INFUSION may increase the risk of heart problems. Therefore, please inform your doctor if you have any pre-existing heart problems before prescribing EXPAVON INFUSION .

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Geriatrics

Consult your doctor

Please consult your doctor before giving EXPAVON INFUSION to elderly people.

What if I have taken an overdose of EXPAVON INFUSION

This medication is given under strict medical supervision where your heart rate, blood pressure, and fluid levels are constantly monitored. If an accidental overdose occurs, the medical staff is trained to recognise the signs immediately (such as fluid overload or kidney strain) and will take prompt corrective action. If you feel sudden shortness of breath or tightness in your chest, tell your healthcare provider right away.

Diet & Lifestyle Advise

Recovering from severe blood loss and fluid replacement requires careful lifestyle adjustments. Here are some practical tips to support your recovery:

  • Monitor your fluid intake: Your doctor will provide specific guidelines on how much water and other fluids you should drink. Follow these closely to prevent straining your kidneys or heart.
  • Eat iron-rich foods: If your treatment was due to blood loss, focus on iron-rich foods such as leafy green vegetables, lean meats, beans, and iron-fortified cereals to help your body rebuild red blood cells.
  • Rest and limit physical exertion: Allow your body time to recover. Avoid strenuous physical activity or heavy lifting until your doctor confirms your blood volume and pressure have fully stabilised.
  • Keep follow-up appointments: Attend all scheduled medical checkups so your doctor can perform blood and kidney tests to ensure your body is recovering well.
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How Soon It Starts Working

The time required for EXPAVON INFUSION to start to work: EXPAVON INFUSION starts to show its action within a few minutes of administration. The time for which the effects of EXPAVON INFUSION last: The effect of EXPAVON INFUSION usually lasts for 6-8 hours.

What if you forget to take EXPAVON INFUSION

Since this medicine is injected by healthcare professionals in a hospital or clinical setting, it is highly unlikely that you will miss a dose. If you have any concerns about your treatment schedule, talk to your doctor or nurse.

Storage

• However, if you need to store it, keep it at a controlled room temperature, ideally between 15°C and 25°C.

Drug Warnings

  • Check the solution: Before the injection is given, ensure the medical provider inspects the bag to verify the liquid is completely clear and the container is leak-free.
  • Monitor kidney function: Because EXPAVON INFUSION carries a risk of causing kidney damage, your doctor must monitor your kidney function through regular blood and urine tests during and after treatment.
  • Watch for bleeding signs: Inform your healthcare team immediately if you notice blood in your urine, nosebleeds, or bleeding gums, as this medicine can affect how your blood clots.
  • Report skin itching: Be aware that itching can sometimes develop weeks after receiving this medicine. Let your healthcare provider know if this becomes severe or uncomfortable.
  • Ensure sterile delivery: This medicine must only be given using sterile techniques to avoid introducing infections into your bloodstream.

verifiedApollotooltip

The following medicines may require additional caution because EXPAVON INFUSION can affect fluid balance, kidney function, and blood clotting:

  • Anticoagulants and other blood-thinning medicines: Using EXPAVON INFUSION with medicines that affect blood clotting may increase the risk of bleeding or interfere with normal clotting. Your doctor may monitor your blood clotting parameters when appropriate.
  • Medicines that can affect kidney function: Medicines such as certain antibiotics and NSAIDs may increase kidney-related risks when used in patients receiving EXPAVON INFUSION , particularly when kidney function is already reduced. Tell your doctor about all medicines you are taking.

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verifiedApollotooltip

No clinically significant food interactions are known with EXPAVON INFUSION when used as directed.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[BLOOD SUBSTITUTES AND PLASMA EXPANDERS]

FAQs

EXPAVON INFUSION belongs to the group of medications called plasma volume expanders used to treat hypovolemia (low blood volume).
EXPAVON INFUSION contains Hydroxyethyl starch. It works by drawing water into the bloodstream, increasing plasma volume and improving circulation. It helps maintain blood pressure and organ perfusion in cases of hypovolemia (low blood volume). Its effects are temporary and depend on dose, molecular weight, and infusion rate.
Contact your doctor if you experience allergic reactions such as headache, fever, abnormal heartbeat, or breathing issues. Seek medical attention for unusual bruising or bleeding, as these may indicate serious side effects. Additionally, report any other unexpected symptoms to your doctor.
The common side effects of EXPAVON INFUSION include itching, reduced plasma proteins, decreased haematocrit, and increased serum amylase. Most of these side effects gradually resolve on their own over time. However, please consult the doctor if these side effects persist or worsen.
Store EXPAVON INFUSION at 15°C–25°C and do not freeze. Keep it out of sight and reach of children.
Yes, in some cases, especially in critically ill patients, this medicine can cause kidney injury. Your medical team will monitor your kidney health closely with regular tests. Talk to your doctor if you have a history of kidney disease.
Unlike normal saline, EXPAVON INFUSION contains larger molecules that stay inside the blood vessels longer, helping to expand blood volume more effectively when simple fluids are not enough. Talk to your doctor about which fluid is best for your condition.
No, this medicine must only be given in a hospital or clinical setting by trained healthcare professionals who can monitor your vital signs and fluid levels. Talk to your doctor if you have questions about your treatment environment.
Yes, itching is a known side effect of EXPAVON INFUSION and can sometimes develop several weeks after your treatment has ended. Talk to your doctor or pharmacist for advice on how to manage this discomfort.
This medicine is only used during pregnancy if your doctor determines that the potential benefits outweigh the risks to the baby. Talk to your doctor if you are pregnant or planning to become pregnant.
This medicine works very rapidly, typically beginning to expand blood volume and stabilise your blood pressure immediately during the infusion. Talk to your doctor for more specific details about your recovery.

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Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - EXP0050
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