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Evoxil-HP Kit is used in the treatment of peptic ulcer disease caused by infection with a common type of bacteria called Helicobacter pylori (H. pylori). It kills bacteria or prevents their growth. Also, it reduces the amount of acid produced in the stomach. It may cause common side effects, such as nausea, diarrhoea, vomiting, stomach pain, taste change, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMOXYCILLIN-750MG+CLARITHROMYCIN-500MG+PANTOPRAZOLE-40MG

Manufacturer/Marketer :

Leeford Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Evoxil-HP Kit

Evoxil-HP Kit is an oral combination medicine prescribed to treat Helicobacter pylori (H. pylori) bacterial infections in the stomach and digestive tract. By clearing this infection, it helps heal peptic ulcers and reduces the risk of ulcers returning. This combination works by lowering stomach acid and eliminating the bacteria responsible for ongoing stomach irritation and ulcer formation.

To get the best results, take Evoxil-HP Kit exactly as prescribed by your doctor, usually twice daily. It is generally taken before meals, commonly before breakfast and the evening meal, so the acid-reducing component can work effectively. Most treatment courses last about 7–14 days, depending on your doctor's recommendation and your individual condition.

Some people may experience mild side effects such as a temporary change in taste, mild diarrhea, nausea, or headache. These effects are often temporary and improve after treatment is completed. However, if you develop severe watery diarrhea, persistent stomach cramps, severe skin reactions, or yellowing of the skin or eyes, contact your doctor promptly.

Before starting Evoxil-HP Kit, tell your doctor if you have liver disease, kidney problems, heart rhythm disorders, or a history of allergies to penicillin antibiotics, macrolide antibiotics, or proton pump inhibitors. Your doctor will review your medical history to make sure this treatment is appropriate for you.

Avoid alcohol during treatment, as it may worsen stomach irritation and increase side effects such as nausea or dizziness. If you are pregnant, breastfeeding, elderly, or taking multiple medicines, consult your doctor before starting treatment. Because antibiotic resistance can affect treatment success, your doctor may select this therapy based on local resistance patterns and current treatment guidelines.

Uses of Evoxil-HP Kit

Evoxil-HP Kit is used in the treatment of Peptic ulcer disease. The detailed uses of Evoxil-HP Kit are as follows:

  • Helicobacter pylori (H. pylori) Infection: Evoxil-HP Kit eliminates the specific bacteria responsible for stomach irritation and ulcers, stopping the infection from spreading.
  • Peptic Ulcer Disease: By lowering stomach acid and clearing bacteria, Evoxil-HP Kit allows painful sores in the stomach lining or upper small intestine to heal completely.
  • Chronic Gastritis: It relieves severe inflammation of the stomach lining caused by bacterial overgrowth, reducing persistent stomach pain and bloating.

Key Benefits

Evoxil-HP Kit helps treat H. pylori infection and promote healing of stomach and duodenal ulcers by addressing the underlying cause of the condition. By reducing stomach acid and eliminating the infection, it helps relieve digestive discomfort and supports long-term recovery. Benefits may include:

  • Helps eliminate H. pylori bacteria from the digestive tract.
  • Supports healing of stomach and duodenal ulcers.
  • Reduces stomach acid and helps relieve burning pain and discomfort.
  • Improves symptoms such as indigestion, bloating, and stomach irritation.
  • Helps reduce the risk of ulcer recurrence when the full treatment course is completed.
  • Supports long-term digestive health and recovery.

Directions for Use

  • Take Evoxil-HP Kit 30-60 minutes before food as advised by your doctor.
  • It is advised to take Evoxil-HP Kit as directed by your doctor, at the same time each day for best results.
  • Swallow Evoxil-HP Kit as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Evoxil-HP Kit Works

Evoxil-HP Kit contains Pantoprazole, Amoxycillin, and Clarithromycin. • Pantoprazole: It helps reduce the amount of acid produced in the stomach. This relieves symptoms such as heartburn and stomach pain and helps the stomach lining heal. • Amoxycillin: It is an antibiotic that helps kill the bacteria responsible for the infection, helping clear it from the body. • Clarithromycin: It is an antibiotic that helps stop the growth and multiplication of bacteria, supporting the treatment of the infection.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Evoxil-HP Kit. Alcohol intake leads to increased production of stomach acid.

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Pregnancy

Consult your doctor

Consult your doctor before taking Evoxil-HP Kit if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor before taking Evoxil-HP Kit. Your doctor will decide whether Evoxil-HP Kit can be taken by breastfeeding mothers or not.

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Driving

Caution

Evoxil-HP Kit causes dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Evoxil-HP Kit if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Evoxil-HP Kit if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Evoxil-HP Kit should not be given to children as the safety and effectiveness were not established.

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Heart

Caution

Evoxil-HP Kit should be taken with caution in patients with heart problems. Please inform your doctor about any existing heart problems before using Evoxil-HP Kit.

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Geriatrics

Safe if prescribed

Evoxil-HP Kit is safe for use in elderly patients if prescribed by the physician.

What if I have taken an overdose of Evoxil-HP Kit

If you accidentally take more than your prescribed dose, seek medical attention immediately or contact your local poison control center. Symptoms of an overdose may include severe stomach upset, vomiting, or confusion.

Diet & Lifestyle Advise

  • Eat smaller, frequent meals: Choose smaller meals throughout the day to reduce strain on your stomach and help prevent excess acid production.
  • Avoid stomach-irritating foods and drinks: Limit spicy foods, citrus fruits, tomatoes, caffeine, and carbonated beverages, as they can irritate the stomach lining and worsen symptoms.
  • Limit fried and high-fat foods: Avoid greasy, fried, and high-fat meals, as they take longer to digest and may increase acid reflux and stomach discomfort.
  • Avoid smoking: Do not smoke, as nicotine can weaken the valve between the esophagus and stomach and slow the healing of ulcers.
  • Manage stress effectively: Practice stress-relieving activities such as deep breathing, meditation, or walking, as stress can increase stomach acid production and aggravate symptoms.
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Have a query?

How Soon It Starts Working

  • The time required for Evoxil-HP Kit to start to work: The time required for Evoxil-HP Kit to show its action is unknown.
  • The time for which the effects of Evoxil-HP Kit last: The duration of action for Evoxil-HP Kit is unknown.

What if you forget to take Evoxil-HP Kit

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Inspect the medicine before use: Check the blister pack before taking the medicine and do not use it if the packaging is damaged.
  • Complete the full course of treatment: Continue taking the medicine for the entire prescribed duration, even if your symptoms improve before finishing the pack. Completing the full course helps improve treatment success and reduces the risk of the infection returning.
  • Do not share your medication: Evoxil-HP Kit has been prescribed specifically for you and should not be given to anyone else.
  • Watch for severe diarrhoea: Contact your doctor if you develop severe watery diarrhoea during treatment or within several weeks after completing treatment. Avoid self treating with antidiarrheal medicines until you have received medical advice, as this may occasionally indicate a serious intestinal infection.
  • Inform healthcare providers before tests or procedures: Tell your doctor, dentist, or other healthcare professionals that you are taking Evoxil-HP Kit before undergoing medical tests or procedures.
  • Attend recommended follow-up testing: Your doctor may recommend a follow-up H. pylori test, usually at least 4 weeks after treatment, to confirm that the infection has been successfully cleared.

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Drug-Drug Interactions

  • Blood thinners (e.g., warfarin): Taking these medicines alongside Evoxil-HP Kit may increase the risk of bleeding and may require closer monitoring.
  • Heart medicines (e.g., digoxin): Evoxil-HP Kit may increase digoxin levels in the body, raising the risk of side effects and toxicity.
  • Certain HIV medicines (e.g., atazanavir): The pantoprazole component may reduce the absorption and effectiveness of these medicines.
  • Gout medicines (e.g., colchicine): Combining these with Evoxil-HP Kit may increase the risk of colchicine toxicity, particularly in older adults and those with kidney problems.

Drug-Food Interactions

  • Grapefruit and grapefruit juice: Consuming grapefruit products while taking Evoxil-HP Kit may increase the levels of certain components in the bloodstream and raise the risk of side effects.
  • Alcohol: Avoid consuming alcohol while taking Evoxil-HP Kit, as it may irritate the stomach lining and worsen side effects such as nausea, dizziness, and stomach discomfort.

Drug-Disease Interactions

  • Myasthenia gravis: Evoxil-HP Kit may worsen muscle weakness and breathing difficulties in patients with this condition.
  • Liver disease: Patients with liver impairment may require closer monitoring or dose adjustments, as the medicine may accumulate in the body.
  • Kidney disease: Reduced kidney function may affect the removal of some components of Evoxil-HP Kit and increase the risk of side effects.
  • Heart rhythm disorders (e.g., QT prolongation): Evoxil-HP Kit may increase the risk of irregular heartbeats in patients with existing heart rhythm abnormalities.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIULCERS, GASTROINTESTINAL AGENTS]

FAQs

Evoxil-HP Kit is used in the treatment of peptic ulcer disease caused by infection with a common type of bacteria called Helicobacter pylori (H. pylori). It works by inhibiting the action of the gastric proton pump and preventing the growth of microorganisms.
Speak to your doctor if you do not feel better even after taking Evoxil-HP Kit for 14 days. Do not take Evoxil-HP Kit for longer durations unless prescribed by the doctor.
Evoxil-HP Kit may cause dizziness. Drive only if you are alert, and do not operate machinery if you feel dizzy after taking Evoxil-HP Kit.
Avoid or limit the consumption of alcohol while on Evoxil-HP Kit as it may lead to increased dizziness. Alcohol intake may also lead to excess production of stomach acid, thereby increasing acidity and heartburn.
Diarrhoea might be a side-effect of Evoxil-HP Kit. Drink enough fluids and eat fibre-rich food if you experience diarrhoea after taking Evoxil-HP Kit. If you find blood in your stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Evoxil-HP Kit contains pantoprazole, which may increase the risk of bone fracture in the hip, spine, or wrist. Recent clinical studies indicated that pantoprazole may affect the absorption of certain nutrients and minerals required for maintaining good bone health, leading to fractures. This mainly occurs in people taking higher doses of Evoxil-HP Kit for longer durations. Inform your doctor before taking Evoxil-HP Kit if you have osteoporosis or if you are already taking corticosteroids.
Dry mouth could be a side effect of Evoxil-HP Kit. Limiting caffeine intake, avoiding smoking, drinking enough water, and chewing sugar-free gum or candy might help stimulate saliva production and thereby prevent dry mouth.
Inform your doctor if you don’t get better after finishing the full course of treatment. Also, let your doctor know if your symptoms are getting worse while using Evoxil-HP Kit. Your doctor may need to reassess your condition, possibly perform additional tests, and prescribe a different treatment if necessary.
A peptic ulcer is a sore that develops on the lining of your stomach, lower esophagus, or small intestine. It's usually caused by an infection with Helicobacter pylori (H. pylori) bacteria or prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs).
Do not use Evoxil-HP Kit if you have a known hypersensitivity to Evoxil-HP Kit. Use Evoxil-HP Kit with caution if you have liver disease, as the antibiotics in Evoxil-HP Kit can affect liver function. Inform your doctor if you have or ever had gastrointestinal bleeding, diabetes, myasthenia gravis (neuromuscular disease), bone fractures, or hypomagnesemia (low levels of magnesium). Also, let your doctor know if you are breastfeeding, pregnant or planning pregnancy.
Take Evoxil-HP Kit 30-60 minutes before food or as advised by your doctor. Swallow it as a whole with a glass of water. But try to take it at the same time each day for better efficacy. Do not crush or chew it.
No, do not stop using Evoxil-HP Kit even if you feel better, as stopping Evoxil-HP Kit early can leave the infection untreated, which could lead to side effects. Therefore, complete the full course of treatment as prescribed by your doctor.
Common side effects of Evoxil-HP Kit include nausea, diarrhoea, vomiting, stomach pain, altered taste, and headache. If any of these side effects persist or worsen, please consult your doctor.
Yes. Most people can continue consuming dairy products while taking Evoxil-HP Kit. Dairy products do not usually interfere significantly with the effectiveness of this treatment. Follow your doctor's instructions regarding meal timing.
Medicines such as ibuprofen or aspirin may irritate the stomach lining and slow ulcer healing. Speak with your doctor before taking additional pain relievers while being treated for an ulcer.
Evoxil-HP Kit is generally used during pregnancy only when your doctor believes the benefits outweigh the potential risks. If you are pregnant, planning a pregnancy, or breastfeeding, discuss your treatment options with your doctor before starting Evoxil-HP Kit.
Yes. Many doctors recommend a follow-up H. pylori test, such as a stool antigen test or urea breath test, usually at least 4 weeks after completing treatment. This helps confirm that the infection has been successfully cleared.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.484 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Pil.526 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Electronic Medicines Compendium (EMC). Pil.7072 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Drugs.com Clinical Review Team. Amoxicillin Clarithromycin And Omeprazole Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  5. National Center for Biotechnology Information (NCBI). Pmc2974811 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  6. Amoxicillin Amoxicillin. 1974. [Accessed on 01 Feb. 2019]Check here
  7. Pantoprazole sodium sesquihydrate. 2009. [Accessed on 12 Apr. 2019]Check here

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - EV35212
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