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  3. Etolac-400 Sr Tablet 10's

Etolac-400 Sr Tablet 10's, Pack of 10 TabletS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Etolac-400 Sr Tablet is used to treat mild to moderate pain in osteoarthritis and rheumatoid arthritis. It contains Etodolac, which works by reducing the production of a chemical known as prostaglandin, responsible for inducing pain and inflammation in the body. In some cases, you may experience certain common side effects such as stomach pain, diarrhoea, indigestion, headache, loss of appetite, nausea and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

ETODOLAC-400MG

Manufacturer/Marketer :

Systemic Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Etolac-400 Sr Tablet

Etolac-400 Sr Tablet is used to treat mild to moderate pain in osteoarthritis and rheumatoid arthritis. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering (cartilage). Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage.

 

Etolac-400 Sr Tablet works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

 

Take Etolac-400 Sr Tablet with or after food. You are advised to take Etolac-400 Sr Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as stomach pain, diarrhoea, indigestion, headache, loss of appetite, nausea and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you should talk to your doctor if you experience these side effects persistently.

 

Consult your doctor before taking Etolac-400 Sr Tablet if you are pregnant or breastfeeding; your doctor will prescribe Etolac-400 Sr Tablet only if the benefits outweigh the risks. Etolac-400 Sr Tablet may cause drowsiness and dizziness, so drive with caution. Etolac-400 Sr Tablet is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with Etolac-400 Sr Tablet as it could lead to increased drowsiness and dizziness. It could also increase the risk of stomach bleeding.

Uses of Etolac-400 Sr Tablet

Etolac-400 Sr Tablet is used to provide pain relief in conditions like osteoarthritis and rheumatoid arthritis. The detailed uses of Etolac-400 Sr Tablet are as follows:<br/>• Pain Relief: Etolac-400 Sr Tablet is a NSAID used to relieve pain in conditions such as osteoarthritis and rheumatoid arthritis.<br/>• Anti-inflammatory: Etolac-400 Sr Tablet reduces inflammation and swelling in joints and soft tissues and provides relief from tenderness, stiffness, and discomfort in osteoarthritis and rheumatoid arthritis.<br/>

Directions for Use

• Etolac-400 Sr Tablet can be taken with meals to avoid stomach upset.• It is usually taken once daily or as prescribed by your doctor.• Swallow Etolac-400 Sr Tablet as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Etolac-400 Sr Tablet works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Thus, Etolac-400 Sr Tablet helps treat pain associated with osteoarthritis and rheumatoid arthritis.

How Etolac-400 Sr Tablet Works

Etolac-400 Sr Tablet works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Storage

Keep Etolac-400 Sr Tablet out of reach and sight of children.
Side effects of Etolac-400 Sr Tablet
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Etolac-400 Sr Tablet

Do not take more than the prescribed dose of Etolac-400 Sr Tablet as it may cause overdose. The symptoms of overdose include stomach pain, nausea, vomiting, lack of energy, drowsiness, blood/black/tarry stools, vomit that is bloody or looks like coffee grounds or coma. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Etolac-400 Sr Tablet can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart bypass surgery, do not use Etolac-400 Sr Tablet . Do not take Etolac-400 Sr Tablet if you are allergic to Etodolac, have severe heart failure or peptic ulcer, have suffered bleeding problems such as bleeding from stomach or bowels while taking any pain killers or you have liver or kidney problems. Inform your doctor before taking Etolac-400 Sr Tablet if you are taking medicines for high blood pressure and fluid retention. Consult your doctor before taking Etolac-400 Sr Tablet if you are pregnant or breast-feeding, your doctor will prescribe you Etolac-400 Sr Tablet only if the benefits outweigh the risks. Etolac-400 Sr Tablet causes drowsiness and dizziness, so drive only if you are alert. Etolac-400 Sr Tablet should not be given to children as the safety has not been established. Avoid consuming alcohol along with Etolac-400 Sr Tablet as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Inform your doctor before taking Etolac-400 Sr Tablet if you suffer from fluid retention (swelling), high blood pressure, heart problems, asthma or breathing difficulties. Use of Etolac-400 Sr Tablet can make your skin very sensitive to sunlight which can even cause sunburn. So, whenever you step out of home try to apply sunscreen on your skin.

Drug-Drug Interactions

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EtodolacKetorolac
Critical
EtodolacMeloxicam
Critical

Drug-Drug Interactions

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EtodolacKetorolac
Critical
How does the drug interact with Etolac-400 Sr Tablet:
Using ketorolac together with Etolac-400 Sr Tablet may increase the risk of side effects in the gastrointestinal tract (inflammation, bleeding and ulceration).

How to manage the interaction:
Taking Etolac-400 Sr Tablet with Ketorolac is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
EtodolacMeloxicam
Critical
How does the drug interact with Etolac-400 Sr Tablet:
Co-administration of Etolac-400 Sr Tablet with Meloxicam can raise the adverse consequences in the digestive system, including inflammation, bleeding, ulceration, and, in rare cases, perforation(rupture).

How to manage the interaction:
Taking Meloxicam with Etolac-400 Sr Tablet is not recommended can result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness consult a doctor. Do not discontinue any medications without consulting a doctor.
EtodolacOmacetaxine mepesuccinate
Severe
How does the drug interact with Etolac-400 Sr Tablet:
Use of Omacetaxine mepesuccinate with Etolac-400 Sr Tablet may increase the risk of bleeding and severe haemorrhage.

How to manage the interaction:
There may be a possibility of interaction between Etolac-400 Sr Tablet and Omacetaxine mepesuccinate, but it can be taken if prescribed by a doctor. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, and/or weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
EtodolacTolmetin
Severe
How does the drug interact with Etolac-400 Sr Tablet:
When tolmetin is used with Etolac-400 Sr Tablet, there is an increased risk of significant gastrointestinal toxicity (inflammation, bleeding, ulceration, and perforation).

How to manage the interaction:
Taking Etolac-400 Sr Tablet with Tolmetin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
EtodolacDalteparin
Severe
How does the drug interact with Etolac-400 Sr Tablet:
Taking Etolac-400 Sr Tablet with Dalteparin can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although there is a possible interaction between Etolac-400 Sr Tablet and Dalteparin, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
EtodolacOxaprozin
Severe
How does the drug interact with Etolac-400 Sr Tablet:
Taking Oxaprozin with Etolac-400 Sr Tablet may raise the risk of gastrointestinal adverse effects (inflammation, bleeding, ulceration, and, in rare cases, perforation).

How to manage the interaction:
Taking Etolac-400 Sr Tablet with Oxaprozin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, and/or weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
EtodolacFenoprofen
Severe
How does the drug interact with Etolac-400 Sr Tablet:
Taking fenoprofen with Etolac-400 Sr Tablet may raise the risk of gastrointestinal adverse effects (inflammation, bleeding, ulceration, and, in rare cases, perforation).

How to manage the interaction:
Although taking Etolac-400 Sr Tablet and Fenoprofen together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, and/or weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
EtodolacAminolevulinic acid
Severe
How does the drug interact with Etolac-400 Sr Tablet:
Taking Etolac-400 Sr Tablet with aminolaevulinic acid increases may risk of the toxicity of the other.

How to manage the interaction:
Although there is a possible interaction between Aminolaevulinic acid and Etolac-400 Sr Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
EtodolacIopamidol
Severe
How does the drug interact with Etolac-400 Sr Tablet:
Taking Iopamidol and Etolac-400 Sr Tablet can increase the risk of kidney damage.

How to manage the interaction:
Although taking Etolac-400 Sr Tablet and Iopamidol together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor immediately. Drink lots of fluid after the procedure to stay hydrated and to flush the contrast agent out of your kidneys. Do not stop using any medications without talking to a doctor.
EtodolacPhenylbutazone
Severe
How does the drug interact with Etolac-400 Sr Tablet:
Taking phenylbutazone with Etolac-400 Sr Tablet may raise the risk of gastrointestinal adverse effects (inflammation, bleeding, ulceration, and, in rare cases, perforation).

How to manage the interaction:
Although taking Etolac-400 Sr Tablet and Phenylbutazone together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, and/or weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.

Habit Forming

No

Therapeutic Class

ANALGESICS
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Etolac-400 Sr Tablet . Alcohol intake along Etolac-400 Sr Tablet may cause increased drowsiness and drowsiness. It may also increase the risk of stomach bleeding. Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Caution

Please consult your doctor before taking Etolac-400 Sr Tablet if you are pregnant, your doctor will prescribe you Etolac-400 Sr Tablet if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known whether Etolac-400 Sr Tablet passes into the mother’s milk. Please consult your doctor before taking Etolac-400 Sr Tablet if you are breast-feeding, your doctor will prescribe you Etolac-400 Sr Tablet if the benefits outweigh the risks.

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Driving

Caution

Etolac-400 Sr Tablet may cause drowsiness, dizziness or abnormal vision. Do not drive or operate heavy machinery if you feel dizzy or drowsy.

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Liver

Caution

Dose adjustment may be needed in patients with severe liver impairment. Please consult your doctor if you have liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with severe kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Etolac-400 Sr Tablet should not be used by children as the efficacy and safety has not been established.

Have a query?

FAQs

Etolac-400 Sr Tablet is used to treat mild to moderate pain in osteoarthritis and rheumatoid arthritis.

Etolac-400 Sr Tablet works by blocking the effect of chemical messengers (prostaglandin), thereby helping in reducing joint pain, stiffness, swelling and inflammation.

Diarrhoea might be a side-effect of Etolac-400 Sr Tablet . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience excess diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

Etolac-400 Sr Tablet might cause stomach-upset, abdominal pain and indigestion. To prevent this take Etolac-400 Sr Tablet with or after food.

Do not take Etolac-400 Sr Tablet for longer durations or high doses as it may cause heart attack or stroke. Do not exceed the dose and duration prescribed by your doctor.

Do not overdose on Etolac-400 Sr Tablet or any medicine as it could lead to unpleasant side-effects. Take Etolac-400 Sr Tablet only as prescribed by your doctor. Rush to your nearest doctor as early as possible if you have overdosed on Etolac-400 Sr Tablet . Symptoms of overdose include nausea, vomiting, stomach pain, headache, blood in stools/faeces.

Yes, Etolac-400 Sr Tablet might affect certain test results like blood or urine tests. Inform your doctor that you are taking Etolac-400 Sr Tablet before undergoing any tests.

Yes, the use of Etolac-400 Sr Tablet can make the skin very sensitive to sunlight which can even cause sunburn. So, whenever you step out of home try to apply sunscreen on your skin.

Etolac-400 Sr Tablet can increase your risk of a fatal heart attack or stroke. If you have any recent heart bypass surgery, do not use Etolac-400 Sr Tablet .

Etolac-400 Sr Tablet may cause side effects such as diarrhoea, stomach pain, indigestion, loss of appetite, headache, nausea and vomiting. If these side effects persist or worsen, please consult your doctor.

Yes, Etolac-400 Sr Tablet is a pain-relieving medicine.

Etolac-400 Sr Tablet contains Etodolac. It belongs to the class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs).

No, Etolac-400 Sr Tablet is not a narcotic. It belongs to the class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs).

No, Etolac-400 Sr Tablet does not get you high. It does not lead to physical or psychological dependence and does not have the potential to be abused (drug-seeking behaviour). However, consult your doctor if you are not feeling well.

Patients who are allergic to Etolac-400 Sr Tablet or any of its ingredients, should avoid using Etolac-400 Sr Tablet . However, if you are using Etolac-400 Sr Tablet for the first time or if you are not aware of any allergy, please consult your doctor.

Prolonged use and high doses of Etolac-400 Sr Tablet may cause kidney problems, such as blood or protein in urine and pain during urination. Patients with impaired kidney function, heart failure, and hypertension (high blood pressure) are at risk of kidney problems. Patients taking medicines that cause excess urination (diuretics), or medicines which have significant impact on kidney function are also at higher risk of developing kidney problems. Additionally, Etolac-400 Sr Tablet can affect kidneys of patients who are over 65 years of age or who remain dehydrated. Thus, monitoring of kidney function is recommended for such patients.

Etolac-400 Sr Tablet may cause drowsiness and also dizziness and visual disturbances. However, not everyone taking Etolac-400 Sr Tablet will have these effects. If you experience these symptoms, avoid driving or operating heavy machinery.

Etolac-400 Sr Tablet is effective if used in the dose and duration prescribed by your doctor. Even if you see improvement in your condition, do not stop using Etolac-400 Sr Tablet too early as the symptoms may return or worsen.

Country of origin

INDIA

Manufacturer/Marketer address

2nd Floor, Block A, Suryalok Complex, King Koti Rd, Hyderabad, Telangana 500001
Other Info - ETO0273

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:33 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.3857.pdf
  2. https://www.medindia.net/doctors/drug_information/etodolac.htm
  3. https://www.drugs.com/tips/etodolac-patient-tips

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