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  3. ESZ 40 Capsule

ESZ 40 Capsule, Pack of 1 Capsule
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

ESZ 40 Capsule reduces the amount of acid your stomach makes. It treats gastroesophageal reflux disease (GERD), stomach ulcers and Zollinger-Ellison syndrome (overproduction of acid due to pancreatic tumour). It helps in reducing the stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn. In some cases, it may cause common side effects like headache, diarrhoea, nausea, abdominal pain, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ESOMEPRAZOLE-40MG

Manufacturer/Marketer :

TBG Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About ESZ 40 Capsule

ESZ 40 Capsule is used in the treatment of gastroesophageal reflux disease (GERD), stomach ulcers, Zollinger-Ellison syndrome (overproduction of acid due to a pancreatic tumour), and gastric ulcers. It mainly helps reduce the amount of acid your stomach makes. 

ESZ 40 Capsule contains esomeprazole, which helps reduce stomach acid by blocking the action of an enzyme (H+/K+ ATPase, also known as the gastric proton pump), thus prevents the release of stomach acid and relieving symptoms of heartburn.

Not everyone who is taking ESZ 40 Capsule will get these side effects. ESZ 40 Capsule may have common side effects, such as headache, diarrhoea, nausea, abdominal pain, vomiting, dizziness, and joint pain. These side effects are temporary and may resolve on their own over time. However, if these side effects persist, don't hesitate to contact your doctor.

Take ESZ 40 Capsule as advised. Your physician will decide the dosage based on your medical condition. You should take ESZ 40 Capsule 30 minutes before food. It is recommended not to exceed the recommended dose of ESZ 40 Capsule. Do not chew, crush, or break the medicine.

Inform your physician if you are allergic to ESZ 40 Capsule. Tell your doctor if you have stomach or intestinal cancer, liver problems, are allergic to ESZ 40 Capsule or will have an endoscopy in the future. Prolonged intake of ESZ 40 Capsule may cause a deficiency of Vitamin B12 and low levels of calcium, magnesium and Vitamin D, leading to osteoporosis. ESZ 40 Capsule is not recommended for children below 5 years of age. Consult the doctor if you are pregnant or breastfeeding.

Uses of ESZ 40 Capsule

ESZ 40 Capsule is used in the treatment of hyperacidity, heartburn, stomach ulcer and Zollinger-Ellison syndrome. The detailed uses of ESZ 40 Capsule are as follows:

  • Management of Gastroesophageal Reflux Disease (GERD): ESZ 40 Capsule effectively reduces symptoms of GERD, such as heartburn and acid regurgitation, by lowering stomach acid production.
  • Healing of Erosive Esophagitis: ESZ 40 Capsule is often prescribed to promote the healing of inflamed oesophagal tissue caused by prolonged exposure to stomach acid.
  • Treatment of Zollinger-Ellison Syndrome: ESZ 40 Capsule is used to manage Zollinger-Ellison syndrome, a condition that leads to excessive stomach acid production.
  • Eradication of Helicobacter pylori: ESZ 40 Capsule is sometimes included in combination therapy to eliminate Helicobacter pylori infections, which are associated with peptic ulcers.

Directions for Use

  • ESZ 40 Capsule should be taken on an empty stomach, at least 1 hour before a meal, to improve its effectiveness
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow ESZ 40 Capsule as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • ESZ 40 Capsule is effective in healing heartburn, hyperacidity conditions, duodenal ulcers, gastric ulcers, and Crohn’s disease-associated ulcers.
  • ESZ 40 Capsule can be prescribed to all age groups, including special populations like the elderly, pregnant, lactating mothers, and patients with kidney and liver disease.
  • ESZ 40 Capsule helps manage acidity-related conditions, promotes digestion, and provides relief from associated discomfort.

How ESZ 40 Capsule Works

ESZ 40 Capsule helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum. ESZ 40 Capsule prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of ESZ 40 Capsule

Do not take more than the prescribed dose of ESZ 40 Capsule as it may cause overdose. The symptoms of overdose include blurred vision, confusion, drowsiness, sweating, nausea, fast heartbeat, dry mouth, headache or flushing. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Avoid taking ESZ 40 Capsule if you are allergic to it or have any history of gastric cancer, liver disease, low magnesium levels, or low vitamin B1.
  • Prolonged intake of ESZ 40 Capsule may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), vitamin B12, and magnesium deficiency.
  • ESZ 40 Capsule may interact with blood thinners, antifungals, anti-HIV drugs, iron supplements, and anti-cancer medications. Please inform your doctor if you are taking any of these medications.
  • Although ESZ 40 Capsule is safe for use during pregnancy or breastfeeding, inform your doctor if you are pregnant or breastfeeding before starting treatment with ESZ 40 Capsule.
  • Intake of ESZ 40 Capsule may mask the symptoms of gastric cancer, so if you have any severe stomach pain or blood in stool, immediately consult the doctor.
  • ESZ 40 Capsule is not recommended for use in children below 5 years of age.
  • It is always important to check the expiry date of the medicine. Discard the medicine if it reaches the expiry date.

Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
  • Before going to sleep try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows, instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid taking alcohol and smoking cigarette. Alcohol can raise the level of production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter) which prevents backflow of the stomach acid back into the food pipe.
  • Include high fibre containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal. These foods are full of antioxidant, calcium and vitamin B 12 that can help cope with the long term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial in the peptic ulcer and H Pyroli infection.
  • Avoid regular sitting continuously, as it can increase stomach acid production. Try to take a break of 5 minutes in 1 hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS

ESZ 40 Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Drinking alcohol with ESZ 40 Capsule may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid, limit alcohol or contact doctor before intake of ESZ 40 Capsule.

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Pregnancy

Consult your doctor

ESZ 40 Capsule is safe for use in pregnant women. However, please consult your physician before taking the medicine. Your doctor will weigh the benefits and potential risks before prescribing it.

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Breast Feeding

Consult your doctor

ESZ 40 Capsule is safe for use in lactating mothers. However, please consult your physician before taking the medicine. Your doctor will weigh the benefits and potential risks before prescribing it.

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Driving

Caution

In some cases, ESZ 40 Capsule may cause dizziness, sleepy, or blur vision. If you observe these symptoms do not drive or operate heavy machinery until you feel better.

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Liver

Consult your doctor

ESZ 40 Capsule should be taken with precaution in patients with liver disease. Please consult your physician.

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Kidney

Consult your doctor

Patients with kidney disease should consult a doctor before taking ESZ 40 Capsule.

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Children

Caution

ESZ 40 Capsule should not be prescribed for children under 5 years of age. ESZ 40 Capsule is generally prescribed from 5-16 years of children for the treatment of acid-related damage of the food pipe (erosive esophagitis).

Have a query?

FAQs

ESZ 40 Capsule is used to treat Hyperacidity, Heartburn, Stomach ulcer, and Zollinger-Ellison syndrome.

ESZ 40 Capsule is a proton pump inhibitor (PPI), which is a type of medication. Proton pumps are enzymes found in the stomach lining that aid in the production of acid needed for digestion. Esomeprazole impairs the function of proton pumps. This decreases the quantity of acid produced by the stomach.

No. ESZ 40 Capsule prevents excess production of stomach acid causing acid reflux and heartburn. If blood is coming in your stool or mucous immediately contact the doctor.

Yes. ESZ 40 Capsule can alter certain medical tests like neuroendocrine tumours (secretin stimulation test), and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostics test contact your doctor.

It is very unlikely that taking one or two extra doses by accident will cause any problems. However, you should check with your doctor if you have taken too much and have are feeling sweaty, have a fast heartbeat, are feeling sleepy.

There's no firm evidence to suggest that taking ESZ 40 Capsule will reduce fertility in either men or women. However, speak to your doctor if you're trying to get pregnant and do as advised.

You can eat and drink normally while taking ESZ 40 Capsule. However, you should avoid foods that seem to make your indigestion worse, such as rich, spicy and fatty foods. You should also cut down on caffeinated drinks, such as tea, coffee and cola, as well as alcohol.

No. Gas and acidity are two different common discomforts. Acidity is caused when improper functioning of the valve (sphincter) is located at the junction of the stomach and food pipe. As a result stomach acid backflows and enters the upper part of the food pipe causing heartburn. On the other hand, gas is the result of the digestion of the food and drinks eliminating gases like carbon dioxide, hydrogen, nitrogen, methane, etc. from the body.

Prolonged intake of ESZ 40 Capsule may lead to atrophic gastritis (inflammation of stomach cells), Vitamin B12 deficiency and weakening of bones or osteoporosis (loss of calcium, magnesium and vitamin D). Your doctor may prescribe calcium, vitamin D or haemoglobin enhancing medications to cope with long term side effects.

ESZ 40 Capsule should be used in children only if prescribed by the doctor. Please consult the doctor before giving ESZ 40 Capsule to children.

ESZ 40 Capsule should be taken an hour before meals.

ESZ 40 Capsule is usually taken on an empty stomach, first thing in the morning. If you take ESZ 40 Capsule twice a day, take 1 dose in the morning and 1 dose in the evening.

Yes, ESZ 40 Capsule can be taken with domperidone if prescribed by the doctor.

Antacids can be taken along with ESZ 40 Capsule if prescribed by the doctor. However, it is advised to maintain a gap of 2 hours between ESZ 40 Capsule and antacid medicines.

It is advised to take ESZ 40 Capsule for the duration prescribed by the doctor. ESZ 40 Capsule is usually prescribed for a short term. However, it may be indicated for a long term use in cases like Zollinger-Ellison syndrome and ulcer disease.

Do not discontinue ESZ 40 Capsule without consulting your doctor. To treat your condition effectively, take ESZ 40 Capsule for the duration prescribed by the physician.

ESZ 40 Capsule may cause weight gain in rare cases. Maintain a proper weight by eating healthy food and exercising regularly.

Yes, ESZ 40 Capsule is safe to use if prescribed by the doctor.

ESZ 40 Capsule can be taken with ranitidine if prescribed by the doctor. No interactions were found between both the medicines.

Drinking alcohol with ESZ 40 Capsule may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So, try to avoid/limit alcohol consumption with ESZ 40 Capsule.

If you miss a dose of ESZ 40 Capsule take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

ESZ 40 Capsule might cause side effects like headache, diarrhoea, nausea, abdominal pain, and vomiting. Consult the doctor if the side effects persist or worsen.

Consult the doctor before taking other medicines while using ESZ 40 Capsule to prevent interactions. Let the doctor know if you are taking blood thinners, antifungal agents, anti-HIV drugs, anti-viral drugs, iron supplements, antibiotics, cardiac medicines and anti-cancer drugs.

Country of origin

India
Other Info - ES75369

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 6, 2025 | 12:41 PM IST

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Reference

  1. https://www.drugs.com/mtm/esomeprazole.html
  2. https://www.nhs.uk/medicines/esomeprazole/
  3. https://www.medicines.org.uk/emc/files/pil.3002.pdf
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/021153s056,021957s023,022101s020lbl.pdf
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