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compositionComposition:ESTRADIOL VALERATE-2MG
prescription
Prescription Medicine
info
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Estravian Tablet is an hormone medicine used in the treatment of post-menopausal symptoms, osteoporosis, hypoestrogenism and advanced androgen-dependent carcinoma of the prostate. This medicine contains estradiol, which works by enhancing the lowered levels of the sex hormone oestrogen in the peri or post-menopausal female body, thus helps reduce symptoms of menopause such as vaginal dryness, hot flashes (hot face, neck and chest) and weak bones.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ESTRADIOL VALERATE-2MG

Manufacturer/Marketer :

Nivian Pharma Llp

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Estravian Tablet

Estravian Tablet is an oral prescription medication primarily used to relieve moderate to severe menopause symptoms, such as hot flashes, night sweats, and vaginal dryness. It is also used to help prevent osteoporosis (bone thinning) in postmenopausal individuals and to replace estrogen in people whose bodies do not produce enough of this hormone.

To get the best results, take Estravian Tablet at the same time every day, with or without food. If it upsets your stomach, taking it with food may help. Eating foods rich in calcium and vitamin D and doing regular weight-bearing exercise can further support your bone health.

While taking Estravian Tablet , you may experience mild side effects such as headache, breast tenderness, or nausea. However, long-term estrogen therapy may increase the risk of breast cancer and, in people who have a uterus and are not taking a progestin, endometrial (uterine) cancer. Your doctor will carefully assess your individual risks and monitor you regularly during treatment.

If you develop sudden chest pain, severe headache, difficulty breathing, sudden vision changes, severe leg swelling, or weakness on one side of the body, call emergency medical services (dial 112) or go to the nearest emergency department immediately. Also contact your doctor promptly if you notice unusual vaginal bleeding.

Talk to your doctor before starting this medicine if you have high blood pressure, diabetes, gallbladder disease, high cholesterol, or other medical conditions. Do not take this medicine if you have unexplained vaginal bleeding, active liver disease, a history of blood clots, certain estrogen-dependent cancers, or if you are pregnant.

Some medicines, as well as smoking, can increase the risk of serious side effects such as blood clots while taking Estravian Tablet . Avoid smoking during treatment. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor, as this medicine is generally not recommended.

Uses of Estravian Tablet

Estravian Tablet is used in the treatment of Post-menopausal symptoms, Osteoporosis, Hypoestrogenism, and Advanced androgen-dependent carcinoma of the prostate. The detailed uses of Estravian Tablet are as follows:

  • Menopause symptoms: Estravian Tablet helps reduce the frequency and severity of hot flashes, night sweats, and vaginal dryness by replacing the estrogen your body no longer makes.
  • Osteoporosis prevention: It helps maintain bone density in postmenopausal individuals, lowering the risk of fractures and bone thinning.
  • Estrogen deficiency: It restores healthy hormone levels in individuals who suffer from low estrogen due to ovarian failure or other medical conditions.

Key Benefits

  • Relief from daily discomfort: By stabilizing hormone levels, Estravian Tablet helps control sudden hot flashes and night sweats, allowing you to sleep better and feel more comfortable throughout the day.
  • Improved vaginal health: It directly addresses dryness and discomfort during intimacy, restoring tissue health and moisture in the pelvic area.
  • Long-term bone protection: It works quietly to protect your skeleton, keeping your bones stronger and reducing the worry of fractures as you age.
Side effects of Estravian Tablet
  • Use hot or cold packs on your breasts to help alleviate discomfort.
  • Choose a supportive, well-fitting bra, preferably one that has been professionally fitted.
  • Practice relaxation techniques to manage stress and anxiety that may accompany severe breast pain.
  • Limit or avoid caffeine consumption.
  • Eat a low-fat diet and focus on foods rich in complex carbohydrates.
  • Rubbing evening primrose oil on your breasts may help balance fatty acids in the cells and reduce pain.
  • Keep track of when your breast pain occurs and any other symptoms to determine if the pain is regular or not.
  • Vitamin E supplements may help reduce pain for women who experience pain linked to their menstrual cycle.
  • Over-the-counter pain relievers like acetaminophen or ibuprofen can provide relief, but be sure to consult your doctor for the correct dosage, as prolonged use may cause side effects.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Directions for Use

  • Estravian Tablet can be taken with or without food or as advised by the doctor.
  • Follow your doctor's instructions regarding dosage and timing to ensure optimal effectiveness.
  • Swallow Estravian Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Estravian Tablet Works

Estravian Tablet contains an active hormone that is identical to the estrogen naturally produced by the human body. When you take the tablet, it is absorbed into your bloodstream, where it acts as a direct replacement for the falling estrogen levels associated with menopause or ovarian conditions. By binding to estrogen receptors throughout your body, it signals your tissues to behave as they did when your hormone levels were naturally higher. This process regulates your body’s internal thermostat in the brain to stop hot flashes, and it supports cells in the bones, blood vessels, and vaginal tissues to keep them functioning healthily.
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Alcohol

Caution

Caution should be exercised while consuming alcohol with Estravian Tablet as there may be an interaction.

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Pregnancy

Unsafe

Estravian Tablet is indicated for use only in menopausal conditions and is not recommended for use during pregnancy.

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Breast Feeding

Unsafe

Estravian Tablet is indicated for use only in menopausal conditions and is not recommended for use during breastfeeding.

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Driving

Safe if prescribed

Estravian Tablet does not normally affect your ability to drive.

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Liver

Caution

Take Estravian Tablet with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Estravian Tablet should be used with caution in patients suffering from kidney disease. Please consult your doctor in case of any concerns.

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Children

Unsafe

Estravian Tablet is not meant for use by children or adolescents.

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Heart

Caution

Estravian Tablet should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Estravian Tablet .

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Geriatrics

Caution

Limited information is available regarding the use of Estravian Tablet in elderly patients. If you have any concerns about the usage of Estravian Tablet in geriatrics, please consult your doctor.

What if I have taken an overdose of Estravian Tablet

If you take more than your prescribed dose, seek emergency medical care or call a poison control center immediately. Symptoms of an overdose may include severe nausea, vomiting, or unusual vaginal bleeding.

Diet & Lifestyle Advise

  • Prioritize bone-building nutrients: Focus on eating foods rich in calcium (such as dairy products, leafy greens, and fortified foods) and make sure you get enough vitamin D to support bone strength while taking Estravian Tablet .
  • Engage in weight-bearing exercise: Activities like walking, jogging, or resistance training help keep your bones dense and strong, working hand-in-hand with your treatment.
  • Manage hot flash triggers: Limit your intake of caffeine, spicy foods, and alcohol, as these are known to trigger or worsen sudden hot flashes.
  • Stay hydrated: Drink plenty of water throughout the day to help manage dry skin and support overall metabolic health.
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How Soon It Starts Working

The time required for Estravian Tablet to start to work: Estravian Tablet shows its action within 1 to 2 hours of administration. The time for which the effects of Estravian Tablet last: Estravian Tablet effect lasts for 24 hours.

What if you forget to take Estravian Tablet

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is less than 12 hours away, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store Estravian Tablet oral tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Schedule regular medical check-ups and breast screenings (such as mammograms) as recommended by your doctor.
  • Perform monthly breast self-examinations and report any new lumps, pain, nipple discharge, or skin changes promptly.
  • If you still have your uterus, your doctor may prescribe a progestin along with Estravian Tablet to reduce the risk of endometrial (uterine) cancer. Always take both medicines exactly as prescribed.
  • If you need major surgery or expect prolonged bed rest, tell your doctor. You may need to stop Estravian Tablet temporarily to reduce the risk of blood clots.
  • Do not smoke while taking this medicine, as smoking greatly increases the risk of blood clots, stroke, and heart attack during estrogen therapy.
  • If you wear contact lenses and notice vision changes or discomfort, consult your eye specialist, as hormone therapy can occasionally affect the eyes.

Drug-Drug Interactions

verifiedApollotooltip
  • Thyroid medications: Estravian Tablet can affect how your body processes thyroid hormones. Your doctor may need to adjust your thyroid dose.
  • Anticonvulsants (such as carbamazepine or phenytoin): These can make your liver break down Estravian Tablet faster, making it less effective.
  • Antibiotics or antifungals (like rifampin or ketoconazole): These can alter the levels of estrogen in your blood, either lowering the effectiveness or increasing side effects.
EstradiolBivalirudin
Critical
EstradiolPomalidomide
Severe

Drug-Drug Interactions

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EstradiolBivalirudin
Critical
How does the drug interact with Estravian Tablet:
When Etodolac is taken with Bivalirudin, the risk or severity of bleeding and haemorrhage increases.

How to manage the interaction:
Taking Bivalirudin with Estravian Tablet can cause an interaction, consult a doctor before taking it. Do not discontinue any medications without a doctor's advice.
EstradiolPomalidomide
Severe
How does the drug interact with Estravian Tablet:
Co-administration of Estravian Tablet and Pomalidomide can increase the risk of serious blood clots.

How to manage the interaction:
There may be a possibility of interaction between Estravian Tablet and Pomalidomide, but it can be taken if prescribed by a doctor. However, if you experience symptoms like chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EstradiolClindamycin
Severe
How does the drug interact with Estravian Tablet:
When taken in combination, clindamycin can lower the amount or action of Estravian Tablet.

How to manage the interaction:
Co-administration of Estravian Tablet with Clindamycin can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EstradiolCarfilzomib
Severe
How does the drug interact with Estravian Tablet:
Carfilzomib can cause serious blood clots and taking it alongside Estravian Tablet may enhance the risk.

How to manage the interaction:
Co-administration of Estravian Tablet with Carfilzomib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms like chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolThalidomide
Severe
How does the drug interact with Estravian Tablet:
Taking thalidomide together with Estravian Tablet may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking Estravian Tablet and thalidomide together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
EstradiolDantrolene
Severe
How does the drug interact with Estravian Tablet:
The usage of Estravian Tablet with dantrolene might have significant adverse effects on your liver.

How to manage the interaction:
Taking Estravian Tablet with Dantrolene together can result in an interaction, but it can be taken if a doctor has advised it. However, if you have a fever, chills, joint pain or swelling, severe fatigue or weakness, unusual bleeding or bruising, skin rash or itching, lack of appetite, nausea, vomiting, or yellowing of the skin or whites of your eyes, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolAnastrozole
Severe
How does the drug interact with Estravian Tablet:
Estravian Tablet may interfere with anastrozole's function and make it less effective in treating your condition.

How to manage the interaction:
Co-administration of Anastrozole with Estravian Tablet can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EstradiolExemestane
Severe
How does the drug interact with Estravian Tablet:
Using Estravian Tablet with Exemestane may interfere with Exemestane's activity and make it less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Exemestane and Estravian Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
EstradiolLenalidomide
Severe
How does the drug interact with Estravian Tablet:
Coadministration of Estravian Tablet and Lenalidomide can increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between lenalidomide and Estravian Tablet, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolLetrozole
Severe
How does the drug interact with Estravian Tablet:
Letrozole may have a negative effect when used with Estravian Tablet, making it less effective in treating your disease.

How to manage the interaction:
Although taking Letrozole and Estravian Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit juice: Consuming grapefruit or grapefruit juice can raise estrogen levels in your bloodstream, increasing your risk of side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[HORMONES]

FAQs

Estravian Tablet is a hormone replacement therapy used in the treatment of the symptoms of menopause, osteoporosis, hypoestrogenism due to hypogonadism, and advanced androgen-dependent carcinoma of the prostate.
Estravian Tablet works by enhancing the levels of the sex hormone oestrogen in the female body. Thereby, helps treat menopausal symptoms.
Yes, Estravian Tablet is very effective in combating hot flashes in menopausal women.
Estravian Tablet helps with various symptoms of menopause including osteoporosis and weakened bones. However, you may need Vitamin D supplements to address this issue. Discuss with your physician.
You may be advised to stop taking Estravian Tablet about 4 to 6 weeks before surgery to decrease the risk of a blood clot. Therefore, inform your doctor that you are taking Estravian Tablet before undergoing any surgery.
No, Estravian Tablet is not a contraceptive and does not prevent pregnancy. It is a hormone replacement therapy used to manage conditions related to low estrogen levels. If you are able to become pregnant, discuss appropriate contraceptive options with your healthcare provider.
Estravian Tablet comprises the active ingredient Estradiol valerate, which is used as a hormone therapy for menopausal symptoms and hypoestrogenism (low estrogen levels).
If you miss a dose of Estravian Tablet , take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and take your next dose at the usual time. Do not take two doses at once to make up for a missed dose. Always follow your doctor's instructions for dosing.
Estravian Tablet may cause common side effects such as nausea, vomiting, breast soreness, headache, and bloating. Most of these side effects do not require medical attention and will resolve on their own over time. However, please consult your doctor if these side effects persist or become bothersome.
For estrogen deficiency, treatments may include hormone replacement therapy (HRT), such as Estravian Tablet , which can be prescribed by your doctor. Other options include non-hormonal medications, lifestyle changes, and dietary adjustments. It is important to consult with your doctor to determine the most suitable treatment based on your specific health condition.
Estravian Tablet should not be taken by individuals who are allergic to any of its ingredients. It is also not recommended for people with a history of certain health conditions, such as breast cancer, abnormal genital bleeding, blood clots, stroke, myocardial infarction, or liver disease. Always consult your doctor before starting this medication to ensure it is safe for you. Estravian Tablet is intended for use in postmenopausal women and should not be taken if you are pregnant or breastfeeding.
Estravian Tablet should be taken exactly as directed by your doctor. It is usually taken orally, with or without food, at the same time each day. Swallow the medication as a whole with a glass of water. Do not crush, chew, or break it.
You should exercise caution. While many individuals with controlled high blood pressure can use it, estrogen can sometimes cause blood pressure to rise. Your doctor will monitor your blood pressure closely during treatment. Talk to your doctor to see if this is safe for you.
Some people experience mild fluid retention or bloating while taking this medication, which can feel like weight gain. However, significant weight gain is not a standard effect. If you notice rapid or unusual weight changes, talk to your doctor.
This medication is sometimes prescribed to younger individuals who suffer from low estrogen levels due to ovarian failure or other medical conditions. However, it is not a contraceptive and will not prevent pregnancy. Talk to your doctor about your specific needs.
Light breakthrough bleeding or spotting is common during the first few months of hormone therapy. However, any persistent, heavy, or unexpected bleeding should be evaluated immediately to rule out other conditions. Talk to your doctor if this occurs.
Alcohol can increase estrogen levels in your body, which might elevate the risk of side effects. Additionally, heavy alcohol use can put extra strain on your liver. It is best to limit alcohol intake while on this medication. Talk to your doctor for personalized advice.
Estravian Tablet should be used at the lowest effective dose for the shortest duration needed to control your symptoms. Long-term estrogen therapy may increase the risk of conditions such as breast cancer, endometrial (uterine) cancer in people with a uterus who are not taking a progestin, blood clots, and stroke. Your doctor will review your treatment regularly, usually at least once a year, to determine whether continuing therapy is appropriate. Talk to your doctor about the benefits and risks based on your individual health.

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Country of origin

India

Manufacturer/Marketer address

302, Lotus Plaza, Corner Of Gokhle Road And M.G. Road, Village, Naupada, Thane, Maharashtra 400062
Other Info - EST0187
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