In which cases Estrapolis Tablet 28's is not advised?

Do not use Estrapolis Tablet 28's if you are allergic to peanuts, have unusual vaginal bleeding, have/had any cancer (breast or uterus cancer), or undergoing any other estrogen treatment. Tell your doctor if you had a heart attack, stroke, blood clot, or liver problems, if you are pregnant, breastfeeding, or planning to get pregnant.

I need to undergo surgery, can I take Estrapolis Tablet 28's?

No, Estrapolis Tablet 28's should not be taken if you are undergoing surgery. You should inform your doctor, and he might ask you to stop hormone replacement therapy about 4 to 6 weeks before surgery to reduce the risk of blood clots.

Can Estrapolis Tablet 28's cause weight gain?

Estrapolis Tablet 28's may cause weight gain or loss, a common side effect. Regular exercise and a healthy diet can help prevent weight gain.

Can I stop taking Estrapolis Tablet 28's on my own?

Do not discontinue Estrapolis Tablet 28's without consulting your doctor as stopping the medicine can cause your symptoms to come back. Consult the doctor, he/she might reduce the dose gradually.

What if I miss a dose of Estrapolis Tablet 28's?

If you miss a dose of Estrapolis Tablet 28's take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

What can I take for estrogen deficiency?

Foods like flaxseeds, soy, peaches, garlic, sesame seeds, kale, broccoli, Brussels sprouts, peanuts, almonds, cashews, and pistachios can be included in your diet for oestrogen deficiency.

Who should not take Estrapolis Tablet 28's?

Do not take Estrapolis Tablet 28's if you are allergic to any of its components or if you had a heart attack, a stroke, a blood clot, or cancer of the breast, uterus/cervix, or vagina or have undiagnosed vaginal bleeding, liver disease, or a bleeding disorder.

How should Estrapolis Tablet 28's be taken?

Estrapolis Tablet 28's should be swallowed as a whole with water; do not crush or chew it. It can be taken with or without food; taking with food or after meals may help prevent stomach upset.

Estrapolis Tablet 28's

Prescription drug

MRP ₹449.12

(Inclusive of all Taxes)

₹67.4 Cashback (15%)

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Veda Maddala , M Pharmacy

Estrapolis Tablet 28's is used for hormonal replacement therapy for treating hypoestrogenism (estrogen deficiency), osteoporosis (thinning of bones) and symptoms associated with menopause (itching, dryness in the vagina, hot flashes). In addition to this, it also helps in preventing osteoporosis. It is prescribed when the body is not producing a sufficient amount of natural estrogen. It contains estradiol, which regulates the menstrual cycle and ovulation. It works by replacing the normal hormone estrogen functions in the body and treats symptoms associated with menopause. In some cases, it may cause side effects such as headache, bloating, hair loss, nausea, breast pain, weight gain, and irregular vaginal bleeding.

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About Estrapolis Tablet 28's

Estrapolis Tablet 28's is indicated for hormonal replacement therapy for treating hypoestrogenism (estrogen deficiency), osteoporosis (thinning of bones) and symptoms associated with menopause (itching, dryness in the vagina, hot flashes).

Estrapolis Tablet 28's contains estradiol, which works by replacing the normal hormone estrogen functions in the body and treats symptoms associated with menopause.

You may experience headaches, bloating, hair loss, nausea, breast pain, weight gain, and irregular vaginal bleeding in some cases. Most of these side effects of Estrapolis Tablet 28's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

You can take Estrapolis Tablet 28's with food or as advised by your doctor. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. It is advised to take Estrapolis Tablet 28's for as long as your doctor has prescribed it for you, depending upon your medical condition.

Inform your doctor if you have any history of vaginal bleeding, breast cancer, or blood clot in the legs or lungs. If you are pregnant or breastfeeding, please do not take Estrapolis Tablet 28's. While taking Estrapolis Tablet 28's, your doctor may advise regular tests to monitor its working. Grapefruit juice and St.John’s wort (a natural remedy for depression) should not be taken along with Estrapolis Tablet 28's.

Uses of Estrapolis Tablet 28's

Estrapolis Tablet 28's is used in the treatment of hormone replacement therapy, osteoporosis and hypoestrogenism. The detailed uses of Estrapolis Tablet 28's are as follows:

Hormone Replacement Therapy (HRT): Estrapolis Tablet 28's is widely used in hormone replacement therapy to alleviate menopause symptoms, such as hot flashes and vaginal dryness, by supplying estrogen to the body.
Regulation of Menstrual Cycle: Estrapolis Tablet 28's helps regulate menstrual cycles in women with hormonal imbalances, including conditions like polycystic ovary syndrome (PCOS).
Support for Fertility Treatments: Estrapolis Tablet 28's is often utilized in fertility protocols, aiding in the preparation of the uterine lining for implantation during assisted reproductive technologies like IVF.
Management of Menstrual Disorders: Estrapolis Tablet 28's is prescribed to manage various menstrual disorders, such as heavy menstrual bleeding (menorrhagia) and painful menstruation (dysmenorrhea).
Bone Health: By providing estrogen, Estrapolis Tablet 28's supports bone density maintenance and helps reduce the risk of osteoporosis in postmenopausal women, promoting better bone health.

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Directions for Use

Estrapolis Tablet 28's can be taken with or without food; however, taking it with food or after meals may help prevent stomach upset.
Adhere to your doctor's guidance regarding the dosage and timing of this medication for optimal effectiveness.
Swallow Estrapolis Tablet 28's as a whole with a glass of water.
Do not crush, chew, or break it.

Medicinal Benefits

Estrapolis Tablet 28's contains a synthetic female hormone that regulates ovulation and menstruation in women.
Estrapolis Tablet 28's is given as a hormone replacement therapy for estrogen.
It is also used in the treatment to relieve symptoms of menopause, such as mood swings, reduced sex drive, hot flashes, night sweats and vaginal dryness.
In addition to this, it also helps in preventing osteoporosis.
Estrapolis Tablet 28's is prescribed when the body is not producing a sufficient amount of natural estrogen.

How Estrapolis Tablet 28's Works

Estrapolis Tablet 28's contains estradiol, which regulates the menstrual cycle and ovulation. Estrapolis Tablet 28's works by replacing the normal hormone estrogen functions in the body and treats symptoms associated with menopause.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Side effects of Estrapolis Tablet

Breast Pain

Mild physical activity can increase blood flow and lessen pain from tense or irritated muscles.
Pain might be reduced with a supportive, properly fitting bra, particularly when exercising.
Limit or stay away from items that can cause breast pain, like spicy and caffeine-containing foods.
vitamin E medication which could ease breast pain and encourage rest.

Back Pain

Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:

Talk to your doctor about your back pain and potential medication substitutes or dose changes.
Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
To lessen the tension on your back, sit and stand upright and maintain proper posture.
To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
Back discomfort can worsen by bending, twisting, and heavy lifting.
Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Joint Pain

Here are the steps to manage Joint Pain caused by medication usage:

Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.

Pain

Apply a hot/cold pack to the affected area.
Doing gentle exercises can help cope with pain by stretching muscles.
Get enough sleep. It helps enhance mood and lower pain sensitivity.
Avoid alcohol, smoking and tobacco as they can increase pain.
Follow a well-balanced meal.
Meditation and massages may also help with pain.

Common Cold

Here are the steps to manage the medication-triggered Upper respiratory tract infection:

Inform your doctor about the symptoms you're experiencing due to medication.
Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

Itchy Vagina

Wash the vulva with warm water and a mild, unscented soap, avoiding harsh soaps or scrubbing.
Do not douche as it can disrupt the natural balance of bacteria in the vagina.
After bathing, pat the vulva completely dry with a soft towel.
Wear loose-fitting cotton underwear to allow air circulation.
Change wet or sweaty clothing regularly.
Avoid using scented products like feminine hygiene sprays, lotions, and toilet paper.
Wear loose-fitting pants and skirts.
Stress can increase itching, so practice relaxation techniques like meditation and yoga.

What if I have taken an overdose of Estrapolis Tablet 28's

Do not take more than the prescribed dose of Estrapolis Tablet 28's as it may cause overdose. The symptoms of overdose include vomiting, nausea and vaginal bleeding. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Estrapolis Tablet 28's if you are allergic to any of its ingredients.
Inform your doctor if you have breast cancer, vaginal bleeding, blood clot in the leg (deep venous thrombosis), lungs (pulmonary embolism), vein (thrombosis), cancer of the endometrium (womb lining), any blood clotting disorder, recently had a heart attack, liver or kidney disease, porphyria (a group of liver disease), high blood pressure.
Avoid smoking as it greatly increases the risk of blood clots, stroke, and heart attack while taking Estrapolis Tablet 28's.
Grapefruit juice and St. John’s wort (a natural remedy for depression) should not be taken along with Estrapolis Tablet 28's.
Estrapolis Tablet 28's is not recommended for use in pregnant and breastfeeding mothers.
It is advised to take the medicine around the same time daily for best results.

Drug-Drug Interactions

EstradiolBivalirudin

Critical

EstradiolClindamycin

Severe

Drug-Drug Interactions

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EstradiolBivalirudin

Critical

How does the drug interact with Estrapolis Tablet:
When Etodolac is taken with Bivalirudin, the risk or severity of bleeding and haemorrhage increases.

How to manage the interaction:
Taking Bivalirudin with Estrapolis Tablet can cause an interaction, consult a doctor before taking it. Do not discontinue any medications without a doctor's advice.

EstradiolClindamycin

Severe

How does the drug interact with Estrapolis Tablet:
When taken in combination, clindamycin can lower the amount or action of Estrapolis Tablet.

How to manage the interaction:
Co-administration of Estrapolis Tablet with Clindamycin can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.

EstradiolDantrolene

Severe

How does the drug interact with Estrapolis Tablet:
The usage of Estrapolis Tablet with dantrolene might have significant adverse effects on your liver.

How to manage the interaction:
Taking Estrapolis Tablet with Dantrolene together can result in an interaction, but it can be taken if a doctor has advised it. However, if you have a fever, chills, joint pain or swelling, severe fatigue or weakness, unusual bleeding or bruising, skin rash or itching, lack of appetite, nausea, vomiting, or yellowing of the skin or whites of your eyes, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

EstradiolLenalidomide

Severe

How does the drug interact with Estrapolis Tablet:
Coadministration of Estrapolis Tablet and Lenalidomide can increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between lenalidomide and Estrapolis Tablet, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

EstradiolLetrozole

Severe

How does the drug interact with Estrapolis Tablet:
Letrozole may have a negative effect when used with Estrapolis Tablet, making it less effective in treating your disease.

How to manage the interaction:
Although taking Letrozole and Estrapolis Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

EstradiolTranexamic acid

Severe

How does the drug interact with Estrapolis Tablet:
Co-administration of Estrapolis Tablet with Tranexamic acid can increase the risk of blood clots.

How to manage the interaction:
Taking Estrapolis Tablet with Tranexamic acid can lead to an interaction; however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

EstradiolAnastrozole

Severe

How does the drug interact with Estrapolis Tablet:
Estrapolis Tablet may interfere with anastrozole's function and make it less effective in treating your condition.

How to manage the interaction:
Co-administration of Anastrozole with Estrapolis Tablet can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.

EstradiolCarfilzomib

Severe

How does the drug interact with Estrapolis Tablet:
Carfilzomib can cause serious blood clots and taking it alongside Estrapolis Tablet may enhance the risk.

How to manage the interaction:
Co-administration of Estrapolis Tablet with Carfilzomib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms like chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

EstradiolThalidomide

Severe

How does the drug interact with Estrapolis Tablet:
Taking thalidomide together with Estrapolis Tablet may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking Estrapolis Tablet and thalidomide together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

EstradiolPomalidomide

Severe

How does the drug interact with Estrapolis Tablet:
Co-administration of Estrapolis Tablet and Pomalidomide can increase the risk of serious blood clots.

How to manage the interaction:
There may be a possibility of interaction between Estrapolis Tablet and Pomalidomide, but it can be taken if prescribed by a doctor. However, if you experience symptoms like chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

ESTRADIOL-2MGGrapefruit and Grapefruit Juice

Moderate

Drug-Food Interactions

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ESTRADIOL-2MGGrapefruit and Grapefruit Juice

Moderate

Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
The rate of absorption of oral estrogens may be increased by coadministration with grapefruit juice. Avoid or restrict the consumption of grapefruit juice while taking Estrapolis Tablet.

Diet & Lifestyle Advise

Regular exercise and physical activity can minimize hot flashes and improve sleep. Weight-bearing exercises can also help strengthen bones. Aerobics, yoga, and activities like tai chi may help relax the body and mind.
Wear loose clothes before going to bed and sleep in a cool, well-ventilated room. This can prevent symptoms of hot flashes and night sweats. Get a minimum of 8 hours of sleep.
Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
Try to be stress-free to improve your mood swings due to hormonal fluctuations.
Quitting smoking will help reduce hot flashes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Habit Forming

No

Therapeutic Class

HORMONES