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compositionComposition:DIENOGEST-2MG+ETHINYL ESTRADIOL-30MCG
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Prescription Medicine
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Estradine Tablet is a contraceptive medicine used in the prevention of unwanted pregnancy and treatment of menorrhagia and acne. This medicine inhibits the release of potent eggs from the ovary, thus preventing pregnancy. Common side effects include nausea, breast soreness, headache and dizziness.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

DIENOGEST-2MG+ETHINYL ESTRADIOL-30MCG

Manufacturer/Marketer :

Akumentis Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Estradine Tablet

Estradine Tablet is an oral prescription tablet primarily used to prevent pregnancy. It is also prescribed to treat moderate acne in women who have chosen to use oral contraceptives as their method of birth control. Additionally, it helps manage painful, heavy, or irregular menstrual bleeding.

To ensure this medication works effectively, you must take one tablet every day at the same time without fail. You can take Estradine Tablet with or without food, though taking it with food or at bedtime can help reduce mild nausea. Incorporating regular physical activity and eating a balanced diet can further help manage weight and support cardiovascular health while on this medication.

While taking Estradine Tablet , you might experience mild side effects like headache, breast tenderness, or occasional spotting between periods. These symptoms often improve as your body adjusts, but you should contact your doctor immediately if you experience severe headaches, leg swelling, or sudden chest pain.

Do not take this if you are pregnant, have uncontrolled high blood pressure, migraine with aura (a type of migraine associated with visual or sensory symptoms), or a history of blood clots, heart disease, or severe liver disease. Talk to your doctor before starting Estradine Tablet if you have a history of migraines, diabetes, or high cholesterol, as these conditions require close monitoring.

Smoking while taking Estradine Tablet significantly increases your risk of serious heart problems and blood clots, especially if you are over 35 years old. Certain anti-seizure medicines and herbal supplements can make this pill less effective, which is why you must disclose all treatments to your healthcare provider. If you are breastfeeding, consult your doctor, as this tablet may reduce breast milk production. Managing reproductive health and menstrual concerns can sometimes feel overwhelming. Your healthcare provider can help you decide whether this tablet is the right choice for your individual needs and lifestyle.

Uses of Estradine Tablet

Estradine Tablet is used for contraception, treatment of menorrhagia (heavy or prolonged menstrual bleeding), and acne. The detailed uses of Estradine Tablet are as follows:

  • Contraception (Pregnancy Prevention): Estradine Tablet is an effective oral contraceptive that helps prevent pregnancy by suppressing ovulation and altering conditions within the reproductive tract.
  • Moderate Acne Treatment: Estradine Tablet helps improve moderate acne in women who also desire contraception by reducing the effects of hormones that increase oil production in the skin.
  • Heavy Menstrual Bleeding (Menorrhagia): Estradine Tablet helps reduce heavy, prolonged, or painful menstrual bleeding, resulting in lighter, more regular periods.
  • Menstrual Cycle Regulation: It helps regulate menstrual cycles and may improve symptoms associated with hormonal imbalance, such as irregular periods and menstrual discomfort.

Key Benefits

Estradine Tablet helps provide effective contraception while supporting menstrual and hormonal health. By regulating hormone levels, it helps prevent pregnancy and may improve several symptoms associated with the menstrual cycle.

Benefits may include:

• Provides reliable protection against unplanned pregnancy when taken as prescribed.
• Helps regulate menstrual cycles and promotes more predictable periods.
• May reduce heavy menstrual bleeding and relieve painful menstrual cramps.
• Helps improve hormonal acne by reducing excess oil (sebum) production.
• Supports improved skin appearance and texture with consistent use.
• Enhances overall quality of life by improving menstrual comfort and hormonal balance.

Side effects of Estradine Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Use hot or cold packs on your breasts to help alleviate discomfort.
  • Choose a supportive, well-fitting bra, preferably one that has been professionally fitted.
  • Practice relaxation techniques to manage stress and anxiety that may accompany severe breast pain.
  • Limit or avoid caffeine consumption.
  • Eat a low-fat diet and focus on foods rich in complex carbohydrates.
  • Rubbing evening primrose oil on your breasts may help balance fatty acids in the cells and reduce pain.
  • Keep track of when your breast pain occurs and any other symptoms to determine if the pain is regular or not.
  • Vitamin E supplements may help reduce pain for women who experience pain linked to their menstrual cycle.
  • Over-the-counter pain relievers like acetaminophen or ibuprofen can provide relief, but be sure to consult your doctor for the correct dosage, as prolonged use may cause side effects.

Directions for Use

  • Estradine Tablet can be taken with or without food; however, taking it with food may help lower the chance of nausea/vomiting.
  • It is usually to be taken once daily. However, follow your doctor's instructions regarding dosage and timing for optimal results.
  • Swallow Estradine Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Estradine Tablet Works

Estradine Tablet contains Ethinyl Estradiol and Dienogest. Ethinyl Estradiol: It is an estrogen hormone that helps regulate the menstrual cycle and prevents the release of an egg from the ovary each month. Dienogest: It is a progestogen hormone that helps thicken cervical mucus, making it difficult for sperm to reach the egg. It also changes the lining of the womb, making it less suitable for implantation.
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Alcohol

Caution

Caution should be exercised while consuming alcohol with Estradine Tablet as there may be a minor interaction.

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Pregnancy

Unsafe

Estradine Tablet is not recommended for use during pregnancy. Stop taking Estradine Tablet and consult a doctor immediately if you get pregnant while taking Estradine Tablet .

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Breast Feeding

Consult your doctor

Estradine Tablet may affect the production of breast milk. Other forms of contraception are advised as long as breastfeeding continues. Please consult the doctor.

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Driving

Caution

Estradine Tablet is unlikely to affect driving ability. However, Estradine Tablet may cause dizziness. Drive only if you are alert.

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Liver

Consult your doctor

Estradine Tablet should be used with caution in those with liver disease. Please consult your doctor if you have any concerns.

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Kidney

Consult your doctor

Estradine Tablet should be used with caution in those with kidney disease. Please consult your doctor if you have any concerns.

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Children

Unsafe

Use below the age of menarche (first period) is not indicated. Please seek medical advice from your doctor if you have any concerns about this.

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Heart

Caution

Estradine Tablet should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Estradine Tablet .

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Geriatrics

Unsafe

Estradine Tablet is intended for women of reproductive age to prevent pregnancy. It is not indicated for use in elderly or postmenopausal women.

What if I have taken an overdose of Estradine Tablet

If you take more than your prescribed daily dose, you may experience nausea, vomiting, or sudden vaginal bleeding. Seek immediate medical attention or contact a poison control center right away. Seek immediate medical attention, call 112, or visit the nearest emergency department if you experience severe symptoms after taking more tablets than prescribed.

Diet & Lifestyle Advise

  • Avoid smoking: Smoking significantly increases the risk of severe cardiovascular side effects, including blood clots and stroke, while taking Estradine Tablet .
  • Stay hydrated: Drink plenty of water throughout the day to support healthy circulation and reduce the risk of fluid retention.
  • Limit alcohol consumption: Excess alcohol can place extra stress on your liver, which is responsible for processing this medication.
  • Eat a balanced diet: Focus on whole foods, fiber, and lean proteins to help manage blood pressure and cholesterol levels, which can sometimes be affected by hormonal therapies.
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Have a query?

How Soon It Starts Working

The time required for Estradine Tablet to start to work: The time required for Estradine Tablet to show its action is unknown. 

The time for which the effects of Estradine Tablet last: The duration of action for Estradine Tablet is clinically unknown.

What if you forget to take Estradine Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, follow the specific instructions on your pack insert or talk to your doctor or pharmacist. You may need to use a backup birth control method (like condoms) for several days.

Storage

•Store Estradine Tablet tablets at room temperature between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original blister packaging to protect them from light and moisture.

Drug Warnings

  • Monitor your blood pressure regularly: Estradine Tablet may increase blood pressure in some people. Check your blood pressure as advised by your doctor.
  • Remember STI protection: Estradine Tablet helps prevent pregnancy but does not protect against HIV or other sexually transmitted infections (STIs).
  • Inform healthcare providers before surgery: Tell your surgeon or healthcare team if you are taking Estradine Tablet before any surgery or prolonged bed rest, as you may need to stop Estradine Tablet temporarily to reduce the risk of blood clots.
  • Keep an extra supply available: Maintain a spare pack of Estradine Tablet to help avoid missing doses unexpectedly.
  • Manage vomiting or severe diarrhea appropriately: If you vomit or have severe diarrhea within 3 to 4 hours of taking a pill, treat it as a missed dose and follow the instructions provided with your medicine.
  • Attend regular monitoring appointments: Keep all scheduled healthcare visits. Your doctor may recommend periodic blood pressure checks and preventive screenings, such as cervical cancer screening, based on your age and medical history.

Drug-Drug Interactions

verifiedApollotooltip
  • Anti-seizure medicines (e.g., carbamazepine, phenytoin): These medicines may reduce the effectiveness of Estradine Tablet by increasing its breakdown in the body.
  • Tuberculosis medicines (e.g., rifampicin, rifabutin): These medicines may decrease the contraceptive effectiveness of Estradine Tablet . Most other commonly used antibiotics do not affect hormonal contraception.
  • Herbal supplements (e.g., St. John's Wort): These products may reduce the effectiveness of Estradine Tablet and increase the risk of unintended pregnancy.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and grapefruit juice: Consuming grapefruit products while taking Estradine Tablet may increase hormone levels in the body and raise the risk of side effects such as nausea and breast tenderness.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[CONTRACEPTIVES]

FAQs

Estradine Tablet is used as a means of birth control in women who wish to prevent unwanted pregnancy. Additionally, it is also used in the treatment of irregular menstrual cycles and moderate to severe acne.
Estradine Tablet works by suppressing ovulation and by changing cervical mucous thickness, thereby preventing pregnancy and acting as an effective birth control method.
No. Estradine Tablet is not known to have a long-term effect on fertility. Fertility usually returns quickly after stopping the medication, and many women ovulate within a few weeks, although it may take a few months for normal menstrual cycles to become regular again. If you are planning a pregnancy or have concerns about fertility, consult your doctor.
Estradine Tablet is not recommended or indicated in the treatment of any breast tumours or cancers.
It is considered as a missed dose if you vomit within 2 hours of taking Estradine Tablet . So, you should take another dose as soon as you feel better.
Follow your doctor's instructions regarding the dosage. It is taken once daily. Take the tablet at the same time every day to maintain consistent hormone levels in your body. It can be taken with or without food. If you experience stomach upset, you may take it with food.
Estradine Tablet is primarily prescribed as a contraceptive for women and is also used to manage conditions like acne and premenstrual dysphoric disorder (PMDD) in women. It contains a combination of ethinyl estradiol and dienogest, which are hormones that help regulate menstrual cycles and reduce acne in women. However, it is not prescribed for men to manage acne. If you are looking for acne treatment options, it's best to consult a healthcare provider who can recommend appropriate medications and treatments based on your specific needs.
Estradine Tablet may cause common side effects such as nausea, breast soreness, headache and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects consistently.
When taking Estradine Tablet , follow your doctor's instructions carefully. Inform your doctor about your medical history, especially if you have high blood pressure, diabetes, blood clotting disorders, or other significant medical conditions. Do not smoke, particularly if you are over 35 years of age, as smoking significantly increases the risk of blood clots, heart attack, and stroke. Avoid using Estradine Tablet during pregnancy or while breastfeeding unless advised by your doctor. Limit alcohol intake, monitor for side effects, and store the medicine properly.
Limited data regarding using Estradine Tablet in children is available, so do not use it unless the doctor advises.
Estradine Tablet is not recommended for use during pregnancy. It is primarily prescribed as a contraceptive and for managing conditions like acne and premenstrual dysphoric disorder (PMDD) in women who are not pregnant. If you are pregnant and experiencing acne, it's best to consult your healthcare provider for appropriate treatment options.
Estradine Tablet has a proven safety record, with numerous studies demonstrating its efficacy and minimal risk of carcinogenic effects. While some studies suggest a potential increased risk of certain cancers, such as breast, cervical, and liver cancer, the overall risk remains relatively low. In fact, the benefits of taking Estradine Tablet for birth control, PMDD, and acne often outweigh the potential risks for many women, making it a reliable and effective treatment option.
Yes. Unexpected bleeding or spotting (breakthrough bleeding) is common during the first few months of taking Estradine Tablet while your body adjusts to the hormones. It usually improves with continued use. However, if the bleeding is heavy, lasts several days, continues beyond three months, or is accompanied by other concerning symptoms, consult your healthcare provider.
Take the missed tablet as soon as you remember, even if it means taking two tablets on the same day. Refer to the patient leaflet in your pack for specific instructions based on which week of the cycle you missed, and use a backup birth control method for the next 7 days if necessary. Talk to your doctor.
No, Estradine Tablet does not provide any protection against HIV or other sexually transmitted infections. To prevent STIs, you must use a barrier method such as condoms alongside your daily tablet. Talk to your doctor.
Some women may experience mild fluid retention or temporary weight changes when starting Estradine Tablet . This is usually minor and often resolves after a few months as your body adjusts to the hormones. Talk to your doctor.
Yes, it is generally safe to take occasional over-the-counter pain relievers like ibuprofen or acetaminophen while taking Estradine Tablet . However, always consult with a healthcare provider before starting any new medications. Talk to your doctor.
Missing a withdrawal bleed can occasionally happen, especially if you have taken all your tablets correctly. However, if you miss two consecutive periods, miss tablets during the cycle, or think you may be pregnant, take a pregnancy test and contact your healthcare provider for further advice.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 022252S004Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Dienogest Estradiol Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  4. National Center for Biotechnology Information (NCBI). Ethinyl Estradiol + Dienogest Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  5. Mayo Clinic Staff. Art 20045887 Inhalation and Dosage Monograph. Rochester, MN: Mayo Foundation for Medical Education; 2025. [Accessed on 02 Jun. 2026]Check here
  6. Estradiol valerate and estradiol valerate/dienogest [FDA Label]. 2012. [Accessed on 13 Feb. 2020]Check here

Country of origin

India

Manufacturer/Marketer address

204, 2Nd Floor, G-Corp Tech Park, Kasarvadavali, Near Hypercity, Ghodbandar Road, Thane (West) - 400615. ,Maharashtra, India.
Other Info - EST0262
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