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  3. Esotric D 20/15 Tablet 10's

Esotric D 20/15 Tablet 10's, Pack of 10 TabletS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Esotric D 20/15 Tablet is used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers. It contains Esomeprazole and Domperidone, which blocks acid production and increases the movements and contractions of stomach muscles. Thus, helps in treating acidity-related problems. It may cause common side effects, such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

DOMPERIDONE-15MG + ESOMEPRAZOLE-20MG

Manufacturer/Marketer :

Forematrics Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Esotric D 20/15 Tablet

Esotric D 20/15 Tablet belongs to the class of drugs known as Proton pump inhibitors, which reduce the amount of acid your stomach produces. It treats gastroesophageal reflux disease (GERD), stomach ulcers, Zollinger-Ellison syndrome (overproduction of acid due to a pancreatic tumour), duodenal ulcers, gastric ulcers, and Crohn’s disease-associated ulcers.

Esotric D 20/15 Tablet is a combination of Esomeprazole and Domperidone that helps reduce stomach acid by blocking the action of an enzyme (H+/K+ ATPase, also known as the gastric proton pump), thus preventing the release of stomach acid and relieving symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

Not everyone who is taking Esotric D 20/15 Tablet will get these side effects. In some cases, you may experience certain common side effects, such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Most of these side effects do not require medical attention and will resolve over time. However, if you experience these side effects persistently, talk to your doctor.

Take Esotric D 20/15 Tablet as advised. Your physician will decide the dosage based on your medical condition. You should take Esotric D 20/15 Tablet 30 minutes before food. It is recommended not to exceed the recommended dose of Esotric D 20/15 Tablet . Do not chew, crush, or break the medicine.

Inform your physician if you are allergic to Esotric D 20/15 Tablet . Consult your doctor before taking Esotric D 20/15 Tablet if you are pregnant or breastfeeding. Esotric D 20/15 Tablet may cause dizziness, so drive only if you are alert. Esotric D 20/15 Tablet should not be given to children as safety has not been established. Avoid consuming alcohol and Esotric D 20/15 Tablet as it could lead to increased drowsiness and elevate stomach acid production.

Uses of Esotric D 20/15 Tablet

Esotric D 20/15 Tablet is used to treat Gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and Stomach ulcers. The detailed uses of Esotric D 20/15 Tablet are as follows:

  • Gastric reflux disease (GERD): By lowering stomach acid, Esotric D 20/15 Tablet helps control GERD symptoms such as acid reflux, regurgitation, and heartburn.
  • Ulcer Treatment: Esotric D 20/15 Tablet promotes healing and inhibits recurrence by treating duodenal and stomach ulcers.
  • Zollinger-Ellison Syndrome: By lowering the production of excessive stomach acid, Esotric D 20/15 Tablet helps to control symptoms and avoid problems.
  • Management of Erosive Esophagitis: Esotric D 20/15 Tablet heals oesophagal damage brought on by acid reflux by treating erosive esophagitis.
  • Relief from nausea and vomiting: Esotric D 20/15 Tablet offers immediate relief by blocking certain substances in the body that cause nausea and vomiting.

Directions for Use

  • Take Esotric D 20/15 Tablet an hour before your meal, ideally in the morning or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Esotric D 20/15 Tablet is effective in healing erosive esophagitis (inflammation of the food pipe), heartburn, Zollinger-Ellison syndrome, duodenal ulcers, gastric ulcers, and Crohn’s disease-associated ulcers.
  • Esotric D 20/15 Tablet works by irreversibly blocking the proton pump gate, which secretes stomach acid. It can be prescribed to all age groups, including special populations like the elderly, pregnant, lactating mothers, and patients with kidney and liver disease.
  • Esotric D 20/15 Tablet helps manage acidity-related conditions, promotes digestion, and provides relief from associated discomfort.

How Esotric D 20/15 Tablet Works

Esotric D 20/15 Tablet is a combination of two drugs: Esomeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Esomeprazole works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the movements and contractions of stomach muscles. Together, Esotric D 20/15 Tablet helps in treating acidity-related problems.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Esotric D 20/15 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • If you experience any anticholinergic effects such as dry mouth, constipation, paralytic ileus, accommodation disorders, or risk of urinary retention after taking a medicine, inform your doctor so that they may lower the dose or switch to alternative medicine.
  • Increase your intake of fluids to relieve dry mouth and constipation.
  • Avoid bright lights and change the temperature in your surroundings.
  • Apply moisturizer to the skin.
  • Assess the function of your bladder and bowels.
  • Suck on hard candy to relieve dry mouth.
  • Include foods rich in fiber like legumes, whole grains, nuts, vegetables and fruits to relieve constipation.

What if I have taken an overdose of Esotric D 20/15 Tablet

Do not take more than the prescribed dose of Esotric D 20/15 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Avoid taking Esotric D 20/15 Tablet if you are allergic to Esotric D 20/15 Tablet or have any history of gastric cancer, liver disease, low magnesium levels, or low vitamin B1.
  • Inform your doctor before taking Esotric D 20/15 Tablet if you have severe kidney, heart or liver disease, or if you are due to have Chromogranin A blood test; if you have fungal infections, heart problems or HIV infection.
  • Talk to your doctor if you experience weight loss, problems with swallowing, stomach pain, indigestion, vomit food or blood, or if you pass black stools while taking Esotric D 20/15 Tablet .
  • On long-term treatment, Esotric D 20/15 Tablet may cause low magnesium levels, vitamin B12 levels, and might increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition.
  • Consult your doctor if you are pregnant or breastfeeding.
  • Esotric D 20/15 Tablet may cause dizziness, so drive only if you are alert.
  • Avoid caffeine-containing beverages (coffee, tea), spicy/deep-fried/processed foods, carbonated drinks, and acidic foods like citrus fruits/vegetables (tomatoes).
  • Esotric D 20/15 Tablet should not be given to children as safety has not been established.
  • Avoid consuming alcohol along with Esotric D 20/15 Tablet as it could lead to increased drowsiness and can elevate the production of stomach acid.
  • A prolonged intake of Esotric D 20/15 Tablet is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor. 

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
EsomeprazoleErlotinib
Severe

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with Esotric D 20/15 Tablet:
Esotric D 20/15 Tablet may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking Esotric D 20/15 Tablet with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
EsomeprazoleErlotinib
Severe
How does the drug interact with Esotric D 20/15 Tablet:
Coadministration of erlotinib and Esotric D 20/15 Tablet can reduce effects of erlotinib.

How to manage the interaction:
Taking Erlotinib and Esotric D 20/15 Tablet together is generally avoided as it can possibly result in an interaction. It can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
EsomeprazoleGefitinib
Severe
How does the drug interact with Esotric D 20/15 Tablet:
Taking gefitinib with Esotric D 20/15 Tablet may reduce the effectiveness of gefitinib.

How to manage the interaction:
Although taking Esotric D 20/15 Tablet and Gefitinib together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Gefitionib 12 hours before or after taking Esotric D 20/15 Tablet. Do not stop taking any medications without consulting a doctor.
EsomeprazoleCitalopram
Severe
How does the drug interact with Esotric D 20/15 Tablet:
Combining Esotric D 20/15 Tablet with Citalopram can increase the risk of irregular heart rhythm. .

How to manage the interaction:
Co-administration of Esotric D 20/15 Tablet with Citalopram can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any symptoms like irregular heart rhythm, dizziness, fainting, or shortness of breath, it's important to contact your doctor immediately. Do not stop using any medications without a doctor's advice.
EsomeprazolePazopanib
Severe
How does the drug interact with Esotric D 20/15 Tablet:
Esotric D 20/15 Tablet decreases the absorption of Pazopanib. This results in reduced efficacy of Pazopanib.

How to manage the interaction:
Although taking Esotric D 20/15 Tablet and Pazopanib can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.
EsomeprazoleNelfinavir
Severe
How does the drug interact with Esotric D 20/15 Tablet:
Taking nelfinavir with Esotric D 20/15 Tablet may decrease the effects of nelfinavir.

How to manage the interaction:
Although taking Esotric D 20/15 Tablet and Nelfinavir can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.
EsomeprazoleDacomitinib
Severe
How does the drug interact with Esotric D 20/15 Tablet:
Esotric D 20/15 Tablet can make Dacomitinib less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Esotric D 20/15 Tablet with Dacomitinib can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleMethotrexate
Severe
How does the drug interact with Esotric D 20/15 Tablet:
Co-administration of methotrexate and Esotric D 20/15 Tablet can increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although taking Esotric D 20/15 Tablet with Methotrexate can result in an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience headache, dizziness, nausea and vomiting. Do not discontinue any medications without consulting a doctor.
EsomeprazoleTacrolimus
Severe
How does the drug interact with Esotric D 20/15 Tablet:
Taking tacrolimus with Esotric D 20/15 Tablet may significantly increase the blood levels of tacrolimus, which can lead to an increased risk of side effects.

How to manage the interaction:
Although taking Esotric D 20/15 Tablet with Tacrolimus can result in an interaction, they can be taken together if prescribed by your doctor. However, contact a doctor immediately if you experience irregular heartbeat, blurring of vision, fever, chills, or muscle spasms. Do not discontinue any medications without consulting a doctor.
EsomeprazoleAtazanavir
Severe
How does the drug interact with Esotric D 20/15 Tablet:
Esotric D 20/15 Tablet reduces the absorption of atazanavir, resulting in reduced efficacy of atazanavir.

How to manage the interaction:
Although there is a possible interaction between Esotric D 20/15 Tablet and atazanavir, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating as it causes acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Esotric D 20/15 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Esotric D 20/15 Tablet . Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

bannner image

Pregnancy

Consult your doctor

Consult your doctor before taking Esotric D 20/15 Tablet if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor before taking Esotric D 20/15 Tablet ; your doctor will decide whether Esotric D 20/15 Tablet can be taken by breastfeeding mothers or not.

bannner image

Driving

Unsafe

Esotric D 20/15 Tablet may cause dizziness. Do not drive or operate machinery unless you are alert.

bannner image

Liver

Consult your doctor

Dose adjustment may be needed. Consult your doctor before taking Esotric D 20/15 Tablet if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Consult your doctor

Dose adjustment may be needed. Consult your doctor before taking Esotric D 20/15 Tablet if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

Esotric D 20/15 Tablet should not be given to children as safety and effectiveness were not established.

Have a query?

FAQs

Esotric D 20/15 Tablet is used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers.

Esotric D 20/15 Tablet contains Esomeprazole and Domperidone. Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the movements and contractions of stomach muscles. Together, Esotric D 20/15 Tablet helps in treating acidity.

Diarrhoea might be a side-effect of Esotric D 20/15 Tablet . Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience excessive diarrhoea or if you find blood in your stools.

Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.

Dry mouth could be a side-effect of Esotric D 20/15 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent drying of the mouth.

Esotric D 20/15 Tablet contains domperidone which helps in treating nausea and vomiting by increasing the movements and contractions of stomach muscles.

Do not take Esotric D 20/15 Tablet for longer durations unless prescribed by the doctor. Consult your doctor if your condition does not improve even after taking Esotric D 20/15 Tablet for 14days.

Esotric D 20/15 Tablet should not be taken along with HIV medicines such as atazanavir, ritonavir, nelfinavir, and saquinavir as Esotric D 20/15 Tablet might affect their absorption. Consult your doctor before taking Esotric D 20/15 Tablet with other medicines to avoid unpleasant side-effects.

On long-term treatment, Esotric D 20/15 Tablet might increase the risk of bone fracture in the spine, wrist or hip. Inform your doctor if you have osteoporosis or if you are taking corticosteroids, as they can increase the risk of bone fractures.

Esotric D 20/15 Tablet belongs to a group of gastrointestinal agents. It contains Esomeprazole and Domperidone, which help treat acidity-related conditions.

Yes, it is safe to use Esotric D 20/15 Tablet if prescribed by the doctor. Take it in the dose and duration prescribed by the doctor.

Take Esotric D 20/15 Tablet on an empty stomach, 1 hour before meals.

Esotric D 20/15 Tablet may cause abnormal heartbeat. Consult the doctor if you have symptoms of irregular heartbeat like fainting, dizziness, and palpitations.

Esotric D 20/15 Tablet should not be used if you are allergic to any of its components or other proton pump inhibitors (such as pantoprazole, rabeprazole, lansoprazole or omeprazole); if you are taking nelfinavir (used to treat HIV); if you have prolactinoma (tumour of the pituitary gland), blockage in intestines, bleeding in stomach or intestine, moderate to severe liver disease, low level of potassium or magnesium or high levels of magnesium, or heart problems.

Dry mouth could be a side effect of Esotric D 20/15 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent mouth drying.

Esotric D 20/15 Tablet may cause dizziness. Do not drive or operate machinery unless you are alert.

Yes, inform the doctor if you are pregnant or breastfeeding before taking Esotric D 20/15 Tablet . The doctor will prescribe Esotric D 20/15 Tablet if the benefits outweigh the risks.

If you miss a dose of Esotric D 20/15 Tablet take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

Avoid consumption of alcohol while taking Esotric D 20/15 Tablet . Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

Store Esotric D 20/15 Tablet at room temperature (not exceeding 30°C) protected from light and moisture. Keep out of reach of children.

Side effects of Esotric D 20/15 Tablet include dry mouth, stomach pain, diarrhoea, headache, and flatulence. Talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

Maharana Pratap Rd, Chanakyapuri Road,S.G.Highway,Opp. Sola Civil Hospital, Ahmedabad, Gujarat 380061
Other Info - ESO0337

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 8, 2025 | 11:55 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.ciplamed.com/content/esomac-d-capsules
  2. https://vibcare.co.in/esomeprazole-domperidone-sr/
  3. https://www.dmpharma.co.in/Esomeprazoledomperidone.html
  4. https://wellonapharma.com/product/finished/esomeprazole-and-domperidone-capsules

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