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  1. Home
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  3. Esmoreg L 75mg/40mg Soft Gelatin Capsule

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Esmoreg L 75mg/40mg Soft Gelatin Capsule, Pack of 1 Capsule
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Extra 15% Off with Bank Offers

Composition :

ESOMEPRAZOLE-40MG + LEVOSULPIRIDE-75MG

Manufacturer/Marketer :

Regulus Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

About Esmoreg L 75mg/40mg Soft Gelatin Capsule

Esmoreg L 75mg/40mg Soft Gelatin Capsule is used to treat gastro-oesophageal reflux disease (GERD). Gastroesophageal reflux disease occurs when stomach acid frequently flows back into the food pipe (oesophagus); this causes acidity, pain and heartburn.

Esmoreg L 75mg/40mg Soft Gelatin Capsule contains Esomeprazole and Levosulpiride. Esomeprazole works by preventing the production of stomach acid. Levosulpiride works by increasing the stomach and intestinal movement and preventing the backflow of food and acid into the mouth.

In some cases, you may experience certain common side effects such as headache, abdominal pain, constipation, diarrhoea, flatulence, nausea and vomiting. You are advised to talk to your doctor if you experience these side effects persistently.

Before taking this medicine, you should tell your doctor if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Esmoreg L 75mg/40mg Soft Gelatin Capsule should not be given to children as safety has not been established.

Uses of Esmoreg L 75mg/40mg Soft Gelatin Capsule

Esmoreg L 75mg/40mg Soft Gelatin Capsule is used to treat acid-related stomach disorders. The detailed uses of Esmoreg L 75mg/40mg Soft Gelatin Capsule are as follows:

  • Gastro-oesophageal reflux disease (GERD): Esmoreg L 75mg/40mg Soft Gelatin Capsule is used to treat acid reflux, heartburn, and irritation of the food pipe (oesophagus).
  • Acidity: Esmoreg L 75mg/40mg Soft Gelatin Capsule helps to reduce excessive stomach acid production and related discomfort.
  • Heartburn: Esmoreg L 75mg/40mg Soft Gelatin Capsule treats the burning sensation in the chest due to acid reflux.
  • Peptic ulcers: Esmoreg L 75mg/40mg Soft Gelatin Capsule helps in the healing of ulcers in the stomach and upper intestine by lowering acid production.
  • Indigestion: Esmoreg L 75mg/40mg Soft Gelatin Capsule improves digestion by reducing acid and promoting normal stomach movement.

Have a query?

Directions for Use

  • Esmoreg L 75mg/40mg Soft Gelatin Capsule should be taken 1 hour before a meal, preferably in the morning.
  • It is usually taken once daily or as prescribed by your doctor.
  • Swallow Esmoreg L 75mg/40mg Soft Gelatin Capsule as a whole with a glass of water.
  • Do not crush, break, or open it.

Medicinal Benefits

  • Esmoreg L 75mg/40mg Soft Gelatin Capsule belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD).
  • Esomeprazole (proton pump inhibitor) works by blocking the action of an enzyme called the gastric proton pump, which is responsible for the production of acid.
  • Levosulpiride (prokinetic agent) works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth.
  • Esmoreg L 75mg/40mg Soft Gelatin Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn.

How Esmoreg L 75mg/40mg Soft Gelatin Capsule Works

Esmoreg L 75mg/40mg Soft Gelatin Capsule contains Esomeprazole and Levosulpiride. Esomeprazole works by blocking the action of an enzyme called the gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Esmoreg L 75mg/40mg Soft Gelatin Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Esmoreg L 75mg/40mg Soft Gelatin Capsule
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

What if I have taken an overdose of Esmoreg L 75mg/40mg Soft Gelatin Capsule

Do not take more than the prescribed dose of Esmoreg L 75mg/40mg Soft Gelatin Capsule as it may cause severe side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Esmoreg L 75mg/40mg Soft Gelatin Capsule if you are allergic to any of its contents, if you are taking nelfinavir (anti-HIV), if you have a gastrointestinal haemorrhage, mechanical obstruction or perforation, epilepsy, mania, porphyria, or cardiac impairment.
  • Inform your doctor before taking Esmoreg L 75mg/40mg Soft Gelatin Capsule if you have severe liver or kidney problems; if you are due to have a Chromogranin A test; if you experience unexplained weight loss, stomach pain, indigestion, vomiting food or blood, or if you pass black stools.
  • On long-term treatment, Esmoreg L 75mg/40mg Soft Gelatin Capsule may increase the risk of bone fractures.
  • Do not take Esmoreg L 75mg/40mg Soft Gelatin Capsule if you are pregnant or breastfeeding.
  • Esmoreg L 75mg/40mg Soft Gelatin Capsule may cause dizziness and drowsiness, so drive only if you are alert.
  • Esmoreg L 75mg/40mg Soft Gelatin Capsule should not be given to children as safety has not been established.
  • Avoid consuming alcohol along with Esmoreg L 75mg/40mg Soft Gelatin Capsule as it could lead to increased drowsiness and can elevate the production of stomach acid.

Drug-Drug Interactions

verifiedApollotooltip
EsomeprazoleRilpivirine
Critical
EsomeprazoleGefitinib
Severe

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with Esmoreg L 75mg/40mg Soft Gelatin Capsule:
Esmoreg L 75mg/40mg Soft Gelatin Capsule may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking Esmoreg L 75mg/40mg Soft Gelatin Capsule with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
EsomeprazoleGefitinib
Severe
How does the drug interact with Esmoreg L 75mg/40mg Soft Gelatin Capsule:
Taking gefitinib with Esmoreg L 75mg/40mg Soft Gelatin Capsule may reduce the effectiveness of gefitinib.

How to manage the interaction:
Although taking Esmoreg L 75mg/40mg Soft Gelatin Capsule and Gefitinib together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Gefitionib 12 hours before or after taking Esmoreg L 75mg/40mg Soft Gelatin Capsule. Do not stop taking any medications without consulting a doctor.
EsomeprazoleCitalopram
Severe
How does the drug interact with Esmoreg L 75mg/40mg Soft Gelatin Capsule:
Combining Esmoreg L 75mg/40mg Soft Gelatin Capsule with Citalopram can increase the risk of irregular heart rhythm. .

How to manage the interaction:
Co-administration of Esmoreg L 75mg/40mg Soft Gelatin Capsule with Citalopram can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any symptoms like irregular heart rhythm, dizziness, fainting, or shortness of breath, it's important to contact your doctor immediately. Do not stop using any medications without a doctor's advice.
EsomeprazoleNelfinavir
Severe
How does the drug interact with Esmoreg L 75mg/40mg Soft Gelatin Capsule:
Taking nelfinavir with Esmoreg L 75mg/40mg Soft Gelatin Capsule may decrease the effects of nelfinavir.

How to manage the interaction:
Although taking Esmoreg L 75mg/40mg Soft Gelatin Capsule and Nelfinavir can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.
EsomeprazoleMethotrexate
Severe
How does the drug interact with Esmoreg L 75mg/40mg Soft Gelatin Capsule:
Co-administration of methotrexate and Esmoreg L 75mg/40mg Soft Gelatin Capsule can increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although taking Esmoreg L 75mg/40mg Soft Gelatin Capsule with Methotrexate can result in an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience headache, dizziness, nausea and vomiting. Do not discontinue any medications without consulting a doctor.
EsomeprazoleDacomitinib
Severe
How does the drug interact with Esmoreg L 75mg/40mg Soft Gelatin Capsule:
Esmoreg L 75mg/40mg Soft Gelatin Capsule can make Dacomitinib less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Esmoreg L 75mg/40mg Soft Gelatin Capsule with Dacomitinib can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleErlotinib
Severe
How does the drug interact with Esmoreg L 75mg/40mg Soft Gelatin Capsule:
Coadministration of erlotinib and Esmoreg L 75mg/40mg Soft Gelatin Capsule can reduce effects of erlotinib.

How to manage the interaction:
Taking Erlotinib and Esmoreg L 75mg/40mg Soft Gelatin Capsule together is generally avoided as it can possibly result in an interaction. It can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
EsomeprazoleAcalabrutinib
Severe
How does the drug interact with Esmoreg L 75mg/40mg Soft Gelatin Capsule:
Esmoreg L 75mg/40mg Soft Gelatin Capsule may interfere with the absorption of Acalabrutinib and reduce their efficacy.

How to manage the interaction:
Taking Esmoreg L 75mg/40mg Soft Gelatin Capsule with Acalabrutinib together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleDasatinib
Severe
How does the drug interact with Esmoreg L 75mg/40mg Soft Gelatin Capsule:
Using Dasatinib together with Esmoreg L 75mg/40mg Soft Gelatin Capsule may decrease the levels of Dasatinib.

How to manage the interaction:
Although taking Esmoreg L 75mg/40mg Soft Gelatin Capsule together with Dasatinib can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
EsomeprazoleClopidogrel
Severe
How does the drug interact with Esmoreg L 75mg/40mg Soft Gelatin Capsule:
Coadministration of Clopidogrel with Esmoreg L 75mg/40mg Soft Gelatin Capsule may reduce the effectiveness of clopidogrel.

How to manage the interaction:
Taking clopidogrel and Esmoreg L 75mg/40mg Soft Gelatin Capsule together possibly has an interaction, but you can take these medications together if your doctor has advised it. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight through regular exercise.
  • Avoid lying down after eating, as it causes acid reflux.
  • Avoid tight-fitting clothes as they might increase the pressure on the abdomen, leading to acid reflux.
  • Practice relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
  • Avoid sitting continuously, as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Esmoreg L 75mg/40mg Soft Gelatin Capsule Substitute

Substitutes safety advice
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Esmoreg L 75mg/40mg Soft Gelatin Capsule. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

bannner image

Pregnancy

Unsafe

Esmoreg L 75mg/40mg Soft Gelatin Capsule should not be taken if you are pregnant. Consult your doctor before taking Esmoreg L 75mg/40mg Soft Gelatin Capsule if you are pregnant.

bannner image

Breast Feeding

Unsafe

Esmoreg L 75mg/40mg Soft Gelatin Capsule may pass into breast milk. Consult your doctor before taking Esmoreg L 75mg/40mg Soft Gelatin Capsule if you are breastfeeding.

bannner image

Driving

Caution

Esmoreg L 75mg/40mg Soft Gelatin Capsule may cause dizziness, drowsiness and blurred vision. Do not drive or operate machinery unless you are alert.

bannner image

Liver

Unsafe

Esmoreg L 75mg/40mg Soft Gelatin Capsule should not be used in patients with hepatic impairment. Consult your doctor before taking Esmoreg L 75mg/40mg Soft Gelatin Capsule if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Esmoreg L 75mg/40mg Soft Gelatin Capsule if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

Esmoreg L 75mg/40mg Soft Gelatin Capsule should not be given to children as the safety and effectiveness were not established.

FAQs

Esmoreg L 75mg/40mg Soft Gelatin Capsule is used to treat gastro-oesophageal reflux disease (GERD). Gastroesophageal reflux disease occurs when stomach acid frequently flows back into the food pipe (oesophagus); this causes acidity, pain and heartburn.

Esmoreg L 75mg/40mg Soft Gelatin Capsule is a combination of two drugs, namely: Esomeprazole and Levosulpiride. Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Esmoreg L 75mg/40mg Soft Gelatin Capsule helps in preventing acid reflux, thereby providing relief from acidity.

Diarrhoea might be a side effect of Esmoreg L 75mg/40mg Soft Gelatin Capsule. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in your stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Do not take Esmoreg L 75mg/40mg Soft Gelatin Capsule with nelfinavir (a drug used to treat HIV infections). Consult your doctor before taking Esmoreg L 75mg/40mg Soft Gelatin Capsule with other medications to avoid potential side effects.

Esmoreg L 75mg/40mg Soft Gelatin Capsule contains esomeprazole, which might increase the risk of fracture in the wrist, hip or spine. This mainly occurs in people taking Esmoreg L 75mg/40mg Soft Gelatin Capsule for longer durations. Inform your doctor if you have osteoporosis or if you are taking corticosteroids; your doctor may prescribe calcium and vitamin D supplements.

Esmoreg L 75mg/40mg Soft Gelatin Capsule may cause changes in blood tests for checking liver functioning. Inform the person doing the tests that you are taking Esmoreg L 75mg/40mg Soft Gelatin Capsule.

Dry mouth could be a side effect of Esmoreg L 75mg/40mg Soft Gelatin Capsule. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy may help stimulate saliva and thereby prevent mouth dryness.

Esmoreg L 75mg/40mg Soft Gelatin Capsule works by relieving the symptoms such as heartburn, stomach pain, or irritation. It also neutralises the acid production in the stomach to prevent discomfort.

Esmoreg L 75mg/40mg Soft Gelatin Capsule contains Esomeprazole and Levosulpiride.

The usual recommendation is to take it one hour before the meal, preferably in the morning.

Yes, Esmoreg L 75mg/40mg Soft Gelatin Capsule may cause dizziness and drowsiness, so drive or operate machinery only if you are alert.

Yes, it can help to ease stomach pain.

Store Esmoreg L 75mg/40mg Soft Gelatin Capsule according to the instructions on the leaflet, away from sunlight, at a temperature not exceeding 25°C. Dispose of unused medicine. Keep it out of reach of pets and children.

Esmoreg L 75mg/40mg Soft Gelatin Capsule is usually taken in the morning, one hour before the food, or as directed by the physician.

Esmoreg L 75mg/40mg Soft Gelatin Capsule is contraindicated for use if you are allergic to any of its contents, if you are taking nelfinavir (anti-HIV), if you have a gastrointestinal haemorrhage, mechanical obstruction or perforation, epilepsy, mania, porphyria, or cardiac impairment. It is also contraindicated for use in pregnant and breastfeeding women.

Esmoreg L 75mg/40mg Soft Gelatin Capsule might increase the risk of wrist, hip or spine fracture. This mainly occurs in individuals taking Esmoreg L 75mg/40mg Soft Gelatin Capsule for extended periods.

Common side effects of Esmoreg L 75mg/40mg Soft Gelatin Capsule may include headache, abdominal pain, constipation, diarrhea, flatulence, nausea and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Esmoreg L 75mg/40mg Soft Gelatin Capsule should not be given to children as safety and effectiveness have not been established.

Country of origin

India
Other Info - ES32801

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Sep 26, 2025 | 8:19 AM IST

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Reference

  1. https://www.ciplamed.com/content/esomac-l-capsules
  2. https://www.drugs.com/mtm/esomeprazole.html
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