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compositionComposition:CLOBETASONE-0.05%W/V+KETOCONAZOLE-2%W/V
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Prescription Medicine
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Esavasone Lotion is used to treat dandruff and other scalp conditions caused by fungal infections by targeting the fungus and reducing inflammation, itching, and redness. Some people may experience side effects such as itching, redness, irritation, or a burning sensation at the site of application. If you are using any steroidal cream, lotion, or ointment, inform your doctor before using this medication. Esavasone Lotion is only for external use.

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Written By ,
Reviewed By Praneetha Akunuri , M.Pharmacy
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More about the Product

Composition :

CLOBETASONE-0.05%W/V+KETOCONAZOLE-2%W/V

Manufacturer/Marketer :

Praise Pharma

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Esavasone Lotion

Esavasone Lotion is a topical cream prescribed to treat skin infections that are caused by fungi and accompanied by redness, swelling, and itching. It helps clear up the underlying infection while rapidly soothing the uncomfortable inflammation on the skin's surface. This medication is typically used for conditions like inflamed athlete's foot, ringworm, or sweat rashes.

To get the best results, you should apply Esavasone Lotion consistently at the same times every day as directed by your healthcare provider. For topical medications like this, food intake does not affect how the medicine works, but keeping the affected skin clean and dry is essential. Wearing loose-fitting cotton clothing can also help speed up your recovery by preventing moisture buildup.

While using Esavasone Lotion, you might notice mild local reactions like a slight burning sensation or irritation where the cream was applied. These minor issues usually disappear quickly as your skin gets used to the treatment. However, if you develop severe skin peeling, spreading redness, or signs of an allergic reaction, stop using it and consult your doctor immediately.

Before starting Esavasone Lotion, tell your doctor if you have skin thinning, tuberculosis of the skin, or viral infections like chickenpox or herpes. Do not use this if you have a known allergy to any ingredients in the cream. It is also not suitable for treating acne, rosacea, or itching around the genital areas unless specifically advised by a specialist.

This cream can sometimes interact with other topical products, so let your doctor know about any other ointments or cosmetics you use. If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before applying this medicine to ensure it is safe for your baby. Elderly patients should also seek specific medical advice to ensure they use the correct amount on thinner skin.

Uses of Esavasone Lotion

Your doctor may prescribe Esavasone Lotion for the following conditions:

  • Inflamed fungal skin infections: Esavasone Lotion helps clear the underlying fungal infection while reducing swelling, redness, and severe itching.
  • Eczema or dermatitis with a suspected or confirmed fungal infection: Your doctor may prescribe this combination when eczema or dermatitis is accompanied by a fungal infection. It is not intended for the routine treatment of eczema without a fungal component.
  • Severe sweat rashes (intertrigo): It soothes the raw, painful chafing in body folds and targets the yeast or fungi that thrive in warm, moist areas.

Key Benefits

Using Esavasone Lotion as prescribed helps treat fungal skin infections while relieving the associated inflammation and discomfort. Here are the key benefits you can expect:

  • Treats the fungal infection: Esavasone Lotion helps eliminate the fungi responsible for the infection, preventing its spread and promoting healing.
  • Relieves itching and irritation: It helps reduce itching, burning, stinging, and skin discomfort, improving overall comfort.
  • Reduces redness and inflammation: Esavasone Lotion helps relieve redness, swelling, and inflammation associated with inflamed fungal skin infections.
  • Promotes faster skin healing: By treating both the infection and inflammation, Esavasone Lotion supports quicker healing and helps restore the skin's normal appearance.
  • Helps prevent further skin damage: By relieving itching and irritation, Esavasone Lotion reduces the urge to scratch, which may help lower the risk of skin damage and secondary bacterial infections.
Side effects of Esavasone Lotion 50 ml
  • Keep your skin clean by gently washing your face two times daily and after sweating. Choose a mild and non-abrasive cleanser.
  • Use gentle alcohol-free skin care products. Avoid products that might irritate your skin such as exfoliants, astringents and toners.
  • Acne may also occur due to oil in the hair. Thus, if you have oily hair, shampoo more frequently than you do now and keep your hair away from face.
  • Keep your hands off your face as touching face throughout the day might worsen acne. Also, do not pick, squeeze or pop acne as it will prolong the healing process and increase the risk of dark spots and scarring.
  • Avoid tanning by applying a broad spectrum sunscreen and wearing sun-protective clothing when outdoors.
  • Apply moisturizer immediately after showering or bathing.
  • Use a moisturizer containing lanolin, petroleum jelly, glycerine, hyaluronic acid or jojoba oil.
  • Do not use hot water for bathing. Instead use warm water and limit showers and bath to 5 to 10 minutes.
  • Apply a sunscreen with SPF-30 or higher.
  • Avoid harsh soaps, detergents and perfumes.
  • Do not scratch or rub the skin.
  • Drink adequate water to prevent dehydration.
  • Wear pants, full sleeves and a wide-brimmed hat while going out in the sun.
  • Handle your eyes with care and try not to rub them, as this can make the irritation worse.
  • If you wear contact lenses, take them out to let your eyes have a rest.
  • Use a cool, wet cloth on the eye that's bothering you to help reduce swelling and discomfort.
  • Stay away from things that can bother your eyes, such as smoke, dust, and chemicals.
  • Get lots of rest and don't push yourself too hard, as this can put extra stress on your eyes.
  • If your eyes don't start feeling better or get worse, make an appointment with an eye doctor to get a proper check-up and some advice on how to make your eyes feel better.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Shake Esavasone Lotion well and then apply it evenly to the affected area.
  • Esavasone Lotion is only for external use.
  • Avoid contact with the eyes. In case Esavasone Lotion accidentally comes in contact with the eyes, rinse with water thoroughly.

How Esavasone Lotion Works

Esavasone Lotion contains ketoconazole and clobetasone, which work together to treat fungal skin infections while relieving the associated inflammation and discomfort. Ketoconazole is an antifungal medicine that works by damaging the protective outer membrane of fungal cells. This prevents the fungi from growing and multiplying, eventually eliminating the infection and preventing it from spreading to surrounding skin. Clobetasone is a topical corticosteroid that helps reduce the skin's inflammatory response. It decreases the release of inflammatory substances, relieving redness, swelling, itching, and irritation associated with inflamed fungal skin infections. Together, these active ingredients help clear the fungal infection while reducing inflammation and discomfort, promoting faster healing and restoring the skin's normal appearance.
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Alcohol

Caution

Interaction of Esavasone Lotion with alcohol is unknown. Please consult a doctor before consuming alcohol while using Esavasone Lotion.

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Pregnancy

Caution

Please inform your doctor if you are pregnant before using Esavasone Lotion. Your doctor will prescribe it only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Esavasone Lotion is excreted in human milk. Please consult a doctor before using Esavasone Lotion while breastfeeding.

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Driving

Safe if prescribed

Esavasone Lotion usually does not affect your ability to drive or operate machinery.

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Liver

Safe if prescribed

If you have any concerns regarding the use of Esavasone Lotion in patients with liver problems, please consult a doctor.

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Kidney

Safe if prescribed

If you have any concerns regarding the use of Esavasone Lotion in patients with kidney problems, please consult a doctor.

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Children

Consult your doctor

Typically, Esavasone Lotion is not recommended for children below 12 years, as the safety and effectiveness were not established. Consult your doctor if you have concerns regarding it.

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Heart

Safe if prescribed

Esavasone Lotion is generally considered safe for heart patients. However, please consult your doctor if you have any concerns.

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Geriatrics

Safe if prescribed

Esavasone Lotion is generally considered safe for use in geriatric people when used as directed by the doctor, but it is crucial to take significant precautions because of sensitivities related to aging and the possibility of drug interactions.

What if I have taken an overdose of Esavasone Lotion

An overdose is unlikely when this medicine is applied to the skin as directed. However, if someone accidentally swallows the cream, or if you apply far too much over a large area for a long time, seek immediate medical attention.f

Diet & Lifestyle Advise

  • Keep the affected area clean and dry: Wash the affected skin regularly and dry it thoroughly, as fungi grow best in warm, moist environments.
  • Wear breathable clothing: Choose loose-fitting cotton or other breathable fabrics to reduce sweating and moisture buildup on the skin.
  • Avoid sharing personal items: Do not share towels, clothing, combs, hairbrushes, or bedding to help prevent spreading the fungal infection to others or becoming reinfected.
  • Wash clothing and towels regularly: Clean towels, bedding, and clothing in hot water whenever possible to help reduce fungal contamination.
  • Avoid scratching the affected area: Scratching can damage the skin, delay healing, and increase the risk of secondary bacterial infections.
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How Soon It Starts Working

The time required for Esavasone Lotion to start to work: Esavasone Lotion starts working within a few days of application. The time for which the effects of Esavasone Lotion last: Esavasone Lotion effect usually lasts through regular and consistent use.

What if you forget to take Esavasone Lotion

If you forget to apply Esavasone Lotion, apply it as soon as you remember. If it is almost time for your next scheduled application, skip the missed dose and continue with your regular routine. Do not apply double the amount to make up for a missed application.

Storage

• Store Esavasone Lotion at room temperature, ideally between 15°C and 25°C (59°F to 77°F).

Drug Warnings

  • Avoid use on sensitive areas unless advised: Do not apply Esavasone Lotion to the face, groin, or underarms unless your doctor specifically instructs you to do so.
  • Avoid contact with the eyes and mouth: Keep the cream away from your eyes, nose, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with plenty of water.
  • Do not cover the treated area: Avoid using airtight dressings, plastic wraps, or occlusive bandages unless directed by your doctor, as they can increase medicine absorption and the risk of side effects.
  • Use only for the prescribed duration: Do not use Esavasone Lotion for longer than recommended, as prolonged use of topical corticosteroids may cause skin thinning and other adverse effects.
  • Inspect before use: Check the tube before each use. Do not use the cream if the packaging is damaged or if the cream has changed colour, consistency, or smell.

Drug-Drug Interactions

verifiedApollotooltip
  • Other topical medicines or skin products: Applying other creams, ointments, gels, lotions, medicated cosmetics, or skin preparations to the same area may affect the absorption or effectiveness of Esavasone Lotion and increase the risk of skin irritation. Unless advised by your doctor, avoid using other topical products on the treated area at the same time. 
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Esavasone Lotion when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[CORTICOSTEROIDS AND ANTIFUNGALS]

FAQs

Esavasone Lotion is used to treat dandruff and other scalp conditions caused by fungal infections by targeting the fungus and reducing inflammation, itching, and redness.
Esavasone Lotion contains ketoconazole and clobetasone. It works by combining the effects of these two medicines. Ketoconazole, an antifungal, kills fungi by destroying their cell membranes, treating the skin infection. Clobetasone, a steroid, reduces inflammation and allergies by blocking chemical messengers that cause redness and swelling.
No, you are not recommended to stop using Esavasone Lotion without consulting your doctor, as it may cause recurring infections. Therefore, apply Esavasone Lotion for as long as your doctor has prescribed it, and if you experience any difficulty while using it, please consult your doctor.
Esavasone Lotion should be stored in a cool and dry place away from sunlight. Keep Esavasone Lotion out of the sight and reach of children.
The common side effects of Esavasone Lotion may include itching, redness, irritation, or a burning sensation at the application site. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
No, you should not use Esavasone Lotion to treat acne, rosacea, or common pimples. Applying topical steroids to the face can make acne worse and lead to skin thinning. If you have facial skin concerns, talk to your doctor.
The safety of using this topical combination during pregnancy has not been fully established. It should only be used if the potential benefits outweigh the risks to the unborn baby. Talk to your doctor to discuss safer alternatives.
No, you should not cover the treated area with bandages, dressings, or tight clothing unless your doctor has specifically told you to do so. Covering the area can increase how much medicine your skin absorbs, which increases the risk of side effects. Talk to your doctor if you are unsure.
Mild peeling can sometimes occur as your skin heals. However, if the peeling is severe, painful, or accompanied by spreading redness and swelling, stop using the cream immediately and talk to your doctor.
No, Esavasone Lotion is not recommended for treating diaper rash in infants unless specifically prescribed by a paediatrician. Children are more sensitive to the side effects of topical steroids. Talk to your doctor for safe diaper rash treatments.
No, you should never share your prescription medications with anyone else, even if they have similar symptoms. Their skin condition may require a different treatment, and sharing topical creams can spread skin infections. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Search.Php Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. ESAVASONE LOTION. [Accessed on 02 Jun. 2026]Check here
  3. Ministry of Health and Family Welfare. National Formulary of India (NFI) 2021. 6th ed. New Delhi, India: IPC; 2021. Clinical Drug Monographs: Esavasone Lotion
  4. Robertson DB, Maibach HI Dermatologic Pharmacology. Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 1047-1065
  5. Fox LP, Merk HF, Bickers DR Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, eds. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1679-1706

Country of origin

India

Manufacturer/Marketer address

Block No:1, Paul Warehouse,S.No:222/6, Dhangar Wasti, Mahatma Phule Nagar, Uruli Devachi, Tal.Haveli, Dist. Pune, Maharashtra, India. 412308
Other Info - ESA0024

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