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  3. Epstat SR 150 Tablet 10's

Epstat SR 150 Tablet 10's, Pack of 10 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Epstat SR 150 Tablet is used to treat diabetic neuropathy (diabetic nerve pain). It contains Epalrestat which prevents the accumulation of sorbitol that leads to nerve pain. In some cases, this medicine may cause side effects such as nausea, vomiting, diarrhoea, dizziness, and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

EPALRESTAT-150MG

Manufacturer/Marketer :

Globus Remedies Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Epstat SR 150 Tablet

Epstat SR 150 Tablet is used to manage diabetic neuropathy. Diabetic neuropathy is a chronic progressive nerve disease which causes nerve pain due to nerve damage in diabetic patients. It mostly affects the legs and feet.

Epstat SR 150 Tablet contains ‘Epalrestat’ that works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes, which leads to nerve pain. Epstat SR 150 Tablet prevents the accumulation of sorbitol. Thus, it helps in treating diabetic neuropathy.

Take Epstat SR 150 Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as nausea, vomiting, diarrhoea, dizziness, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking Epstat SR 150 Tablet if you are pregnant or breastfeeding. Epstat SR 150 Tablet may cause drowsiness and dizziness, so drive only if you are alert. Epstat SR 150 Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Epstat SR 150 Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Epstat SR 150 Tablet

Treatment of Diabetic neuropathy (diabetic nerve pain).

Directions for Use

• Epstat SR 150 Tablet should be taken before meals.• It is usually taken 3 times a day, at the same time each day, or as prescribed by your doctor.• Swallow Epstat SR 150 Tablet as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Epstat SR 150 Tablet belongs to a group of medicines called aldose reductase inhibitors. Epstat SR 150 Tablet is used to manage diabetic neuropathy. Epstat SR 150 Tablet works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes, which leads to nerve pain. Epstat SR 150 Tablet prevents sorbitol accumulation, thereby treating diabetic neuropathy (pain due to nerve damage).

How Epstat SR 150 Tablet Works

Epstat SR 150 Tablet contains ‘Epalrestat’ that works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes, which leads to nerve pain. Epstat SR 150 Tablet prevents the accumulation of sorbitol. Thus, it helps in treating diabetic neuropathy.

Storage

Keep Epstat SR 150 Tablet out of reach and sight of children.
Side effects of Epstat SR 150 Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Epstat SR 150 Tablet

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Do not take Epstat SR 150 Tablet if you are allergic to any of its contents. Inform your doctor if you have liver or kidney problems. Consult your doctor before taking Epstat SR 150 Tablet if you are pregnant or breastfeeding. Epstat SR 150 Tablet may cause drowsiness and dizziness, so drive only if you are alert. Epstat SR 150 Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Epstat SR 150 Tablet as it could lead to increased drowsiness and sleepiness.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.

  • Include cayenne pepper in your diet as it can help lower neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain. 

  • Rest well, get plenty of sleep.

  • Try taking a warm bath as it can be soothing.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Epstat SR 150 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Epstat SR 150 Tablet as it may cause increased dizziness.

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Pregnancy

Caution

Limited information is available regarding the use of Epstat SR 150 Tablet in pregnant women. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Limited information is available regarding the use of Epstat SR 150 Tablet in breastfeeding women. Consult your doctor before taking Epstat SR 150 Tablet ; your doctor will decide whether Epstat SR 150 Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Epstat SR 150 Tablet may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Epstat SR 150 Tablet should not be used in patients with severe liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Epstat SR 150 Tablet should be used with caution in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Epstat SR 150 Tablet should not be given to children as safety and efficacy have not been established.

Have a query?

FAQs

Epstat SR 150 Tablet is used to manage diabetic neuropathy, a chronic progressive nerve disease which causes nerve pain due to nerve damage in diabetic patients.

Epstat SR 150 Tablet works by inhibiting aldose reductase enzyme which catalyses the conversion of glucose to sorbitol. Epstat SR 150 Tablet prevents the accumulation of sorbitol, thereby helps in treating diabetic neuropathy.

Diarrhoea could be a side-effect of Epstat SR 150 Tablet . Drink plenty of fluids to prevent dehydration and consume non-spicy meals if you experience diarrhoea. Consult your doctor if you have severe diarrhoea.

Epstat SR 150 Tablet might cause high blood pressure. So, if you have hypertension, consult your doctor before taking Epstat SR 150 Tablet . Regularly monitor blood pressure levels while taking Epstat SR 150 Tablet .

Do not discontinue Epstat SR 150 Tablet without consulting your doctor. To treat your condition effectually, continue taking Epstat SR 150 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Epstat SR 150 Tablet .

Epstat SR 150 Tablet may cause peripheral oedema. Peripheral oedema is the swelling of the hands and lower legs. Avoid sitting or standing for too long. Raise your legs by putting a pillow under the legs while lying down.

Epstat SR 150 Tablet contains epalrestat, which is classified as an Aldose Reductase Inhibitor. It is used for the treatment of diabetic neuropathy.

Some individuals may experience specific common side effects, such as nausea, vomiting, diarrhoea, dizziness, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Follow your doctor's advice and take the right amount of medicine. Be aware of side effects and take care of yourself. If you're pregnant while on treatment, inform your doctor immediately. Don't take other medications unless instructed by the doctor. Alcohol consumption should be avoided. By following these precautions, you'll benefit most from your medicine and stay safe.

In some individuals, Epstat SR 150 Tablet may cause vomiting as it is a common side effect of Epstat SR 150 Tablet . This effect does not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Limited information is available regarding the use of Epstat SR 150 Tablet in pregnant women. Please consult your doctor if you are pregnant or planning to become pregnant before taking Epstat SR 150 Tablet , your doctor will prescribe only if the benefits outweigh the risks.

It is best to consult your doctor before taking any other medicines with Epstat SR 150 Tablet , as some medications may interact with it. Inform your doctor about all the medicines you're currently taking to ensure safe and effective treatment.

Country of origin

India

Manufacturer/Marketer address

14/11, Site-4, Industrial Area, Sahibabad, Ghaziabad (U.P) 201 010
Other Info - EPS0037

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:47 AM IST

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Reference

  1. https://www.mims.com/malaysia/drug/info/epalrestat?mtype=generic
  2. https://www.medindia.net/doctors/drug_information/epalrestat.htm

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