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  3. Epo 150 Tablet SR

Epo 150 Tablet SR, Pack of 1 Tablet
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Epo 150 Tablet SR is used to treat diabetic neuropathy (diabetic nerve pain). It contains Epalrestat which prevents the accumulation of sorbitol that leads to nerve pain. In some cases, this medicine may cause side effects such as nausea, vomiting, diarrhoea, dizziness, and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

EPALRESTAT-150MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Epo 150 Tablet SR

Epo 150 Tablet SR is used to manage diabetic neuropathy. Diabetic neuropathy is a chronic progressive nerve disease which causes nerve pain due to nerve damage in diabetic patients. It mostly affects the legs and feet.

Epo 150 Tablet SR contains ‘Epalrestat’ that works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes, which leads to nerve pain. Epo 150 Tablet SR prevents the accumulation of sorbitol. Thus, it helps in treating diabetic neuropathy.

Take Epo 150 Tablet SR as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as nausea, vomiting, diarrhoea, dizziness, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking Epo 150 Tablet SR if you are pregnant or breastfeeding. Epo 150 Tablet SR may cause drowsiness and dizziness, so drive only if you are alert. Epo 150 Tablet SR is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Epo 150 Tablet SR as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Epo 150 Tablet SR

Treatment of Diabetic neuropathy (diabetic nerve pain).

Directions for Use

• Epo 150 Tablet SR should be taken before meals.• It is usually taken 3 times a day, at the same time each day, or as prescribed by your doctor.• Swallow Epo 150 Tablet SR as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Epo 150 Tablet SR belongs to a group of medicines called aldose reductase inhibitors. Epo 150 Tablet SR is used to manage diabetic neuropathy. Epo 150 Tablet SR works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes, which leads to nerve pain. Epo 150 Tablet SR prevents sorbitol accumulation, thereby treating diabetic neuropathy (pain due to nerve damage).

How Epo 150 Tablet SR Works

Epo 150 Tablet SR contains ‘Epalrestat’ that works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes, which leads to nerve pain. Epo 150 Tablet SR prevents the accumulation of sorbitol. Thus, it helps in treating diabetic neuropathy.

Storage

Keep Epo 150 Tablet SR out of reach and sight of children.

What if I have taken an overdose of Epo 150 Tablet SR

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Do not take Epo 150 Tablet SR if you are allergic to any of its contents. Inform your doctor if you have liver or kidney problems. Consult your doctor before taking Epo 150 Tablet SR if you are pregnant or breastfeeding. Epo 150 Tablet SR may cause drowsiness and dizziness, so drive only if you are alert. Epo 150 Tablet SR is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Epo 150 Tablet SR as it could lead to increased drowsiness and sleepiness.

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.

  • Include cayenne pepper in your diet as it can help lower neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain. 

  • Rest well, get plenty of sleep.

  • Try taking a warm bath as it can be soothing.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Epo 150 Tablet SR Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Epo 150 Tablet SR as it may cause increased dizziness.

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Pregnancy

Caution

Limited information is available regarding the use of Epo 150 Tablet SR in pregnant women. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Limited information is available regarding the use of Epo 150 Tablet SR in breastfeeding women. Consult your doctor before taking Epo 150 Tablet SR; your doctor will decide whether Epo 150 Tablet SR can be taken by breastfeeding mothers or not.

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Driving

Caution

Epo 150 Tablet SR may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Epo 150 Tablet SR should not be used in patients with severe liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Epo 150 Tablet SR should be used with caution in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Epo 150 Tablet SR should not be given to children as safety and efficacy have not been established.

Have a query?

FAQs

Epo 150 Tablet SR is used to manage diabetic neuropathy, a chronic progressive nerve disease which causes nerve pain due to nerve damage in diabetic patients.

Epo 150 Tablet SR works by inhibiting aldose reductase enzyme which catalyses the conversion of glucose to sorbitol. Epo 150 Tablet SR prevents the accumulation of sorbitol, thereby helps in treating diabetic neuropathy.

Diarrhoea could be a side-effect of Epo 150 Tablet SR. Drink plenty of fluids to prevent dehydration and consume non-spicy meals if you experience diarrhoea. Consult your doctor if you have severe diarrhoea.

Epo 150 Tablet SR might cause high blood pressure. So, if you have hypertension, consult your doctor before taking Epo 150 Tablet SR. Regularly monitor blood pressure levels while taking Epo 150 Tablet SR.

Do not discontinue Epo 150 Tablet SR without consulting your doctor. To treat your condition effectually, continue taking Epo 150 Tablet SR for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Epo 150 Tablet SR.

Epo 150 Tablet SR may cause peripheral oedema. Peripheral oedema is the swelling of the hands and lower legs. Avoid sitting or standing for too long. Raise your legs by putting a pillow under the legs while lying down.

Epo 150 Tablet SR contains epalrestat, which is classified as an Aldose Reductase Inhibitor. It is used for the treatment of diabetic neuropathy.

Some individuals may experience specific common side effects, such as nausea, vomiting, diarrhoea, dizziness, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Follow your doctor's advice and take the right amount of medicine. Be aware of side effects and take care of yourself. If you're pregnant while on treatment, inform your doctor immediately. Don't take other medications unless instructed by the doctor. Alcohol consumption should be avoided. By following these precautions, you'll benefit most from your medicine and stay safe.

In some individuals, Epo 150 Tablet SR may cause vomiting as it is a common side effect of Epo 150 Tablet SR. This effect does not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Limited information is available regarding the use of Epo 150 Tablet SR in pregnant women. Please consult your doctor if you are pregnant or planning to become pregnant before taking Epo 150 Tablet SR, your doctor will prescribe only if the benefits outweigh the risks.

It is best to consult your doctor before taking any other medicines with Epo 150 Tablet SR, as some medications may interact with it. Inform your doctor about all the medicines you're currently taking to ensure safe and effective treatment.

Country of origin

India
Other Info - EP75028

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:47 AM IST

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Reference

  1. https://www.mims.com/malaysia/drug/info/epalrestat?mtype=generic
  2. https://www.medindia.net/doctors/drug_information/epalrestat.htm
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