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compositionComposition:PHENYTOIN-100MG
prescription
Prescription Medicine
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Epiwin 100mg Injection is an anti-epileptic medication used in the treatment of severe epileptic seizures/fits, to prevent seizures during or after severe head injury and/or neurosurgery. This medicine works by decreasing the abnormal electrical activity in the brain and thus reduces seizures. Common side effects include nausea, vomiting, headache, and constipation.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

PHENYTOIN-100MG

Manufacturer/Marketer :

Ikon Remedies Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Epiwin 100mg Injection

Epiwin 100mg Injection is a prescription medication given by injection to control and prevent severe, continuous seizures. It is also used to prevent or treat seizures that may occur during or after brain surgery. This medicine belongs to a class of drugs known as anticonvulsants, which help stabilise abnormal electrical activity in the brain.

Because this medicine is given as an injection, a healthcare professional will give it to you in a hospital or clinic setting. The frequency of your doses will depend on your specific medical condition and how you respond to the treatment. Maintaining a regular sleep schedule and avoiding stressful triggers can support your recovery during therapy.

While using Epiwin 100mg Injection, you may experience common side effects like dizziness, sleepiness, or mild coordination issues. However, you must seek immediate medical attention if you notice serious signs such as severe skin rashes, yellowing of the eyes or skin, or unusual bruising. Your healthcare team will closely monitor you during and after the injection to catch any adverse reactions early.

Before starting treatment, tell your doctor if you have a history of liver damage, heart rhythm problems, or diabetes. Do not receive this medicine if you have had a severe allergic reaction to it or similar seizure medicines in the past, or if you have certain slow heart rate conditions.

This medication can interact with alcohol, which may increase drowsiness, and with other medicines that affect liver enzymes, potentially altering the drug's levels in your blood. If you are pregnant, breastfeeding, or an elderly individual, consult your doctor as this treatment requires careful monitoring and dose adjustments to ensure safety.

Uses of Epiwin 100mg Injection

Your doctor may prescribe Epiwin 100mg Injection to help manage the following conditions:

  • Severe prolonged seizures: Helps stop active, continuous seizures by calming overactive nerve cells in the brain.
  • Seizures during or after brain surgery: Prevents seizures from developing due to physical trauma or irritation of brain tissue during surgical procedures.
  • Control of sudden seizure episodes: Acts quickly when oral medications cannot be taken, bringing rapid stability to the nervous system.

Key Benefits

When used as directed as part of your treatment plan, Epiwin 100mg Injection may provide the following benefits:

  • Rapid control in emergencies: Because it is injected directly into a vein, this medicine works quickly to halt dangerous, prolonged seizures, protecting the brain from potential damage.
  • Prevention during recovery: It provides a reliable safeguard against seizures after head injuries or brain surgeries, allowing you to focus on healing without the fear of sudden episodes.
  • Alternative when swallowing is difficult: It offers a dependable option for patients who are unconscious or unable to swallow tablets, ensuring they still receive their vital seizure-control therapy.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Epiwin 100mg Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Epiwin 100mg Injection Works

Epiwin 100mg Injection contains phenytoin. Phenytoin belongs to a group of medicines called antiepileptics (medicines used to prevent and control seizures). It works by blocking voltage-gated sodium channels (proteins in nerve cells that help generate and transmit electrical signals). This reduces the rapid, repetitive electrical activity that causes seizures and prevents abnormal nerve signals from spreading through the brain. As a result, brain activity becomes more stable, helping to control and prevent seizures.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Epiwin 100mg Injection to prevent unpleasant side-effects. It might also affect the concentration of phenytoin in the blood.

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Pregnancy

Caution

Consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe Epiwin 100mg Injection only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while on treatment with Epiwin 100mg Injection. Please consult your doctor if you have any concerns.

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Driving

Unsafe

Epiwin 100mg Injection may cause dizziness and drowsiness. Avoid driving or operating machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed. Epiwin 100mg Injection should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Epiwin 100mg Injection should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Epiwin 100mg Injection can be given to children if prescribed by the doctor.

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Heart

Caution

Epiwin 100mg Injection should be used with caution in patients with heart problems. Please consult your doctor if you have any concerns.

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Geriatrics

Caution

Epiwin 100mg Injection should be used with caution in elderly patients. Please consult your doctor before use.

What if I have taken an overdose of Epiwin 100mg Injection

Seek immediate emergency medical attention if you suspect an overdose. Symptoms of an overdose may include extreme drowsiness, severe nausea, slurred speech, trembling, or loss of balance.

Diet & Lifestyle Advise

  • Get enough sleep: Maintain a regular sleep schedule, as lack of sleep can increase the risk of seizures.
  • Maintain good oral hygiene: Brush and floss your teeth regularly and visit your dentist for routine check-ups, as long-term treatment may cause gum overgrowth (gingival hyperplasia).
  • Avoid alcohol: Alcohol can increase the risk of seizures and may worsen side effects such as dizziness and drowsiness.
  • Support bone health: Eat a balanced diet rich in calcium and vitamin D. Your doctor may recommend supplements if needed, especially during long-term treatment.
  • Identify seizure triggers: Keep a record of your seizures, possible triggers, and any side effects to help your doctor optimise your treatment.
  • Take medicines as prescribed: Follow your treatment plan carefully and attend regular follow-up appointments to help keep your seizures under control.
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How Soon It Starts Working

The time required for Epiwin 100mg Injection to start to work: Epiwin 100mg Injection ideally shows its action within 30 minutes to 1 hour after administration. The time for which the effects of Epiwin 100mg Injection last: The effect of Epiwin 100mg Injection lasts for 24 hours.

What if you forget to take Epiwin 100mg Injection

Because this medicine is usually given by a healthcare provider in a medical setting, missing a dose is highly unlikely. However, if you are on a scheduled treatment plan and miss an appointment, contact your clinic or doctor immediately to reschedule.

Storage

• Store Epiwin 100mg Injection at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Do not stop treatment suddenly: Stopping this medicine abruptly may increase the risk of severe or prolonged seizures. Follow your doctor's advice when changing or stopping treatment.
  • Injection site problems: Consult your doctor right away if you notice pain, swelling, burning, skin discolouration, or blistering around the injection site.
  • Take care with activities requiring alertness: This medicine may cause dizziness, drowsiness, or poor coordination. Avoid driving or operating machinery until you know how it affects you.
  • Attend regular monitoring: Your doctor may perform blood tests and monitor your heart function during treatment to help ensure the medicine remains safe and effective.
  • Tell healthcare professionals: Inform your doctor, dentist, or surgeon that you are receiving this medicine before any medical or dental procedure.
  • Seek urgent medical advice for serious reactions: Consult your doctor right away if you develop a severe skin rash, unusual bruising or bleeding, yellowing of the skin or eyes, worsening seizures, or signs of a severe allergic reaction.
  • Pregnancy: This medicine may harm an unborn baby and has been associated with an increased risk of birth defects (sometimes called fetal hydantoin syndrome). If you are pregnant, think you may be pregnant, or plan to become pregnant, consult your doctor right away.
  • Injection site warning: Consult your doctor right away if you notice severe pain, swelling, blistering, or purple or dark discolouration around the injection site. In rare cases, this medicine can cause Purple Glove Syndrome (a serious reaction that can damage the skin and underlying tissues) and may require urgent treatment.

verifiedApollotooltip
  • Blood thinners (such as warfarin): May increase or decrease the blood-thinning effect, increasing the risk of bleeding or blood clots. Your doctor may monitor your blood tests more closely.
  • Hormonal contraceptives (such as birth control pills, patches, or implants): Phenytoin can make these contraceptives less effective, increasing the risk of unintended pregnancy. Your doctor may recommend an alternative or additional non-hormonal contraceptive method.
  • Other seizure medicines: Some medicines used to treat seizures can affect phenytoin levels or be affected by phenytoin, which may increase side effects or reduce seizure control.
  • Medicines that cause drowsiness: Sleeping tablets, opioid painkillers, some allergy medicines, and anti-anxiety medicines may increase drowsiness, dizziness, and poor coordination.
  • Certain antibiotics, antifungal medicines, antiviral medicines, and medicines for tuberculosis: These may increase or decrease phenytoin levels, making it less effective or increasing the risk of side effects.
  • Some cancer medicines and immunosuppressants: Phenytoin may reduce the effectiveness of these medicines.

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verifiedApollotooltip

No clinically significant food interactions are known with Epiwin 100mg Injection when used as directed. 

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

Epiwin 100mg Injection belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus), and prevent seizures during or after severe head injury and/or neurosurgery. Epiwin 100mg Injection may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion.
Epiwin 100mg Injection works by controlling overactivity of the brain that causes seizures (fits). Thereby, Epiwin 100mg Injection helps in controlling epileptic fits.
Epiwin 100mg Injection can make hormonal contraceptives less effective. Talk to your doctor about using non-hormonal contraceptives like condoms and diaphragm with spermicide to prevent pregnancy.
Epiwin 100mg Injection may cause hyperglycemia (high blood glucose levels). So, inform your doctor if you have diabetes.
Epiwin 100mg Injection may affect the metabolism of vitamin D, which could cause osteomalacia. Inform your doctor if you have bone problems.
Epiwin 100mg Injection might increase blood sugar levels and decrease blood calcium levels, folic acid, phosphate, and vitamin D levels. Inform the person doing the tests that you are taking Epiwin 100mg Injection.
Signs of receiving too much of this medicine include severe drowsiness, rapid involuntary eye movements, slurred speech, loss of balance, or trembling hands. If you or someone else notices these symptoms, seek medical help immediately. Talk to your doctor if you experience any unusual side effects.
No, Epiwin 100mg Injection is an injection that must be given by a trained healthcare professional in a clinic or hospital setting. This ensures your vital signs, like heart rate and blood pressure, can be safely monitored during the process. Talk to your doctor if you have concerns about where you will receive your treatment.
If you feel any burning, pain, swelling, or notice discolouration at the injection site during or after the injection, tell your healthcare provider immediately. These can be signs of tissue irritation that need prompt medical attention. Talk to your doctor or nurse if you experience any discomfort.
Receiving Epiwin 100mg Injection during pregnancy carries risks to the unborn baby but may be necessary in emergency seizure situations. Your doctor will carefully weigh the risks and benefits of this treatment. Talk to your doctor immediately if you are pregnant or planning to become pregnant.
Your doctor will perform regular blood tests to measure the exact amount of the medicine in your bloodstream. This helps ensure you are receiving a safe and effective dose, preventing both under-dosing and toxicity. Talk to your doctor about how often you will need these tests.
You should completely avoid alcohol while using Epiwin 100mg Injection. Alcohol can alter the drug levels in your blood, increase the risk of severe drowsiness, and lower your seizure threshold, making seizures more likely. Talk to your doctor if you find it difficult to avoid alcohol.
Signs of receiving too much of this medicine include severe drowsiness, rapid involuntary eye movements, slurred speech, loss of balance, or trembling hands. If you or someone else notices these symptoms, seek medical help immediately. Talk to your doctor if you experience any unusual side effects.

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