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Epitrate Injection 10 x 1 ml is used for irrigation during eye surgery. It works by constricting blood vessels; this helps maintain pupil dilation during eye surgery. In some cases, it may cause common side effects such as nausea, vomiting, increased heart rate and high blood pressure. Let the doctor know if you are pregnant, breastfeeding, taking other medicines or have pre-existing medical conditions.

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Written By ,
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Sunways (India) Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Epitrate Injection 10 x 1 ml

Epitrate Injection 10 x 1 ml is an emergency injection used to treat life-threatening allergic reactions, also known as anaphylaxis, triggered by insect bites, foods, drugs, or other substances. It works rapidly to reverse severe symptoms like breathing difficulties, swelling of the face and throat, and dangerously low blood pressure. This medicine is a crucial, fast-acting treatment that can save lives during acute medical crises.

Because this medication is used during emergencies, it is not injected on a regular daily schedule. Instead, you should keep it with you at all times and inject it immediately at the first sign of a severe allergic reaction. It can be injected with or without regard to meals. While lifestyle changes like avoiding known allergens do not replace this emergency treatment, they are vital for preventing future severe reactions.

When you inject this medicine, you may experience temporary side effects such as a fast heart rate, shakiness, anxiety, or sweating. These symptoms usually go away quickly as the medicine works, but you must seek immediate emergency medical care after injecting it. If you experience severe chest pain, extreme dizziness, or a throbbing headache, tell the emergency medical team right away.

Do not take this if you are allergic to any of its ingredients, although in a life-threatening emergency, there are no absolute reasons to avoid using it. Before an emergency arises, talk to your doctor if you have heart disease, high blood pressure, thyroid problems, or diabetes. This helps your healthcare team plan the safest way for you to manage severe allergic reactions.

Certain medications, such as some blood pressure drugs or antidepressants, can interact with this medicine and affect how it works in your body. It is also important to talk to your doctor or pharmacist if you are pregnant, breastfeeding, or managing health conditions in elderly individuals to ensure correct use during an emergency.

Uses of Epitrate Injection 10 x 1 ml

Epitrate Injection 10 x 1 ml may be used for the following emergency medical conditions:

  • Severe allergic reactions (anaphylaxis): Epitrate Injection 10 x 1 ml helps by quickly reversing dangerous symptoms like airway swelling, hives, and extremely low blood pressure caused by severe allergies.
  • Emergency heart support: In hospital settings, it helps restore heart function and increase blood pressure during cardiac arrest.
  • Severe asthma attacks: It helps open up narrowed airways in the lungs when other rescue inhalers fail to work.

Key Benefits

The primary benefit of this medicine is its ability to provide immediate, life-saving relief during a severe allergic emergency. Here are the key benefits you can expect:

  • Provides rapid emergency relief: Within seconds of injection, it targets multiple systems in the body to halt the progression of anaphylaxis.
  • Opens the airways: It quickly relaxes the muscles in your lungs, allowing your airways to open up so you can breathe easily during a severe attack.
  • Raises blood pressure: It tightens blood vessels, which helps raise your blood pressure back to a safe level if you go into shock.
  • Reduces dangerous swelling: It rapidly decreases dangerous swelling in the face, tongue, and throat.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Epitrate Injection 10 x 1 ml will be administered by the doctor or healthcare professional in a medical setting.
  • Do not self-administer.

How Epitrate Injection 10 x 1 ml Works

Epitrate Injection 10 x 1 ml contains adrenaline and sodium metabisulphite, which work together to deliver safe and rapid relief. Adrenaline (epinephrine) is the body’s own natural hormone and chemical messenger. The medicine provides additional adrenaline, which rapidly reverses allergic reactions by opening the airways, tightening blood vessels, and supporting the heart. Sodium metabisulphite acts as a stabilising agent and antioxidant to protect the adrenaline from breaking down when exposed to air and light, ensuring the injection remains potent and ready to work instantly in an emergency.
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Alcohol

Caution

The interaction of alcohol with Epitrate Injection 10 x 1 ml is unknown. Please consult a doctor before consuming alcohol with Epitrate Injection 10 x 1 ml.

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Pregnancy

Caution

Please consult a doctor if you are pregnant. Epitrate Injection 10 x 1 ml is administered to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult a doctor if you are breastfeeding. Epitrate Injection 10 x 1 ml is administered to breastfeeding mothers only if the doctor thinks the benefits outweigh the risks.

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Driving

Caution

Epitrate Injection 10 x 1 ml may cause dizziness. Therefore, avoid driving until your vision is clear after administering Epitrate Injection 10 x 1 ml.

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Liver

Consult your doctor

If you have any concerns regarding the use of Epitrate Injection 10 x 1 ml in patients with liver problems, please consult a doctor.

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Kidney

Consult your doctor

If you have any concerns regarding the use of Epitrate Injection 10 x 1 ml in patients with kidney problems, please consult a doctor.

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Children

Caution

Limited information is available. Please consult the doctor if you have any concerns regarding the usage of Epitrate Injection 10 x 1 ml in children.

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Heart

Caution

If you have any concerns regarding the use of Epitrate Injection 10 x 1 ml in patients with heart problems, please consult a doctor.

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Geriatrics

Consult your doctor

Epitrate Injection 10 x 1 ml can be used in the elderly when prescribed by a doctor. If you have any concerns about using Epitrate Injection 10 x 1 ml, please consult a doctor.

What if I have taken an overdose of Epitrate Injection 10 x 1 ml

An overdose can cause a dangerous spike in blood pressure, irregular heartbeats, or fluid in the lungs. If you suspect an overdose or have injected too much, seek immediate medical attention or call emergency services.

Diet & Lifestyle Advise

  • Carry an allergy action plan: Carry an allergy action plan written by your doctor, outlining when and how to use your injection.
  • Avoid known allergy triggers: Identify and strictly avoid your known allergy triggers, such as specific foods, medications, or insect nests.
  • Read food labels carefully: Read food and ingredient labels carefully every time you eat, especially when trying new brands or dining out.
  • Wear medical identification: Wear a medical alert bracelet or necklace that clearly states your severe allergies and that you carry Epitrate Injection 10 x 1 ml.
  • Inform those around you: Inform family members, close friends, and coworkers where you keep your emergency injection and teach them how to use it in case you cannot do it yourself.
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How Soon It Starts Working

The time required for Epitrate Injection 10 x 1 ml to start to work: Epitrate Injection 10 x 1 ml ideally starts to show its action within 1 to 2 minutes of administration. The time for which the effects of Epitrate Injection 10 x 1 ml last: The effect of Epitrate Injection 10 x 1 ml lasts for 2 to 10 minutes.

What if you forget to take Epitrate Injection 10 x 1 ml

Since this medicine is used strictly as an emergency treatment, there is no daily dosing schedule. You do not need to worry about missing a dose, but you must ensure you always carry your prescribed injection with you at all times.

Storage

•Store this medication at room temperature, ideally between 20°C and 25°C (68°F to 77°F).•Keep it in its original outer packaging or carrying case to protect it from light.

Drug Warnings

  • Check the solution: Check the solution through the viewing window regularly; it should be clear and colourless. Do not use it if it is cloudy, coloured, or has floating particles.
  • Check the expiry date: Always inspect the expiry date on your device and replace it before it expires so you are never left without a working medicine.
  • Avoid the needle end: Never put your thumb, fingers, or hand over the needle end of the device to avoid accidental self-injection.
  • Use the correct injection site: Only inject this medicine into the outer thigh. Avoid injecting it into the veins, buttocks, fingers, toes, hands, or feet.
  • Keep a backup device: Keep a backup injection device with you at all times, as some severe reactions may require a second dose if emergency help does not arrive quickly.
  • Call emergency services immediately after use: After using your adrenaline injection, call 108/112 (or your local emergency number) and go to the nearest emergency department, even if you start feeling better.

Drug-Drug Interactions

verifiedApollotooltip
  • Beta-blockers (heart medications): May block the effects of Epitrate Injection 10 x 1 ml, making it less effective, or cause a severe rise in blood pressure.
  • Antidepressants (tricyclics and MAO inhibitors): May increase the risk of dangerous heart rhythms and high blood pressure when combined with this medicine.
  • Digoxin: May increase the sensitivity of your heart, raising the risk of irregular heartbeats.

Drug-Drug Interactions

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How does the drug interact with Epitrate Injection 10 x 1 ml:
Taking Linezolid with Epitrate Injection 10 x 1 ml can increase the risk of high blood pressure.

How to manage the interaction:
Taking Linezolid with Epitrate Injection 10 x 1 ml is not recommended as it can result in an interaction. It should be taken only if a doctor has advised it. However, if you experience confusion, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Epitrate Injection 10 x 1 ml:
Coadministration of Epitrate Injection 10 x 1 ml with Tranylcypromine can increase the risk or severity of high blood pressure or increased heart rate.

How to manage the interaction:
Taking Epitrate Injection 10 x 1 ml with Tranylcypromine is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EpinephrineDihydroergotamine
Critical
How does the drug interact with Epitrate Injection 10 x 1 ml:
When Dihydroergotamine is taken with Epitrate Injection 10 x 1 ml, the amount of Dihydroergotamine in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Dihydroergotamine with Epitrate Injection 10 x 1 ml is not recommended as it can lead to an interaction. It should be taken only if your doctor has advised it. However, if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion, or slurred speech contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EpinephrinePenbutolol
Severe
How does the drug interact with Epitrate Injection 10 x 1 ml:
Coadministration of Penbutolol with Epitrate Injection 10 x 1 ml can lead to high blood pressure and low heart rates.

How to manage the interaction:
Taking Penbutolol with Epitrate Injection 10 x 1 ml together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, irregular heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Epitrate Injection 10 x 1 ml:
Taking Epitrate Injection 10 x 1 ml with Nortriptyline can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Epitrate Injection 10 x 1 ml with Nortriptyline together can result in an interaction, but it can be taken only if your doctor has advised it. It's important to monitor your blood pressure regularly. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Epitrate Injection 10 x 1 ml:
Using Epitrate Injection 10 x 1 ml together with formoterol may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Formoterol and Epitrate Injection 10 x 1 ml together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Epitrate Injection 10 x 1 ml:
Coadministration of Epitrate Injection 10 x 1 ml with Sotalol may reduce the effects of Epitrate Injection 10 x 1 ml. This can lead to low treatment outcomes.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Epitrate Injection 10 x 1 ml, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Epitrate Injection 10 x 1 ml:
Co-administration of Epitrate Injection 10 x 1 ml with Propranolol may cause severe high blood pressure and reduced heart rate.

How to manage the interaction:
Taking Epitrate Injection 10 x 1 ml with Propranolol can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Epitrate Injection 10 x 1 ml:
Coadministration of Epitrate Injection 10 x 1 ml and Imipramine can increase the risk or severity of high blood pressure.

How to manage the interaction:
Although taking Epitrate Injection 10 x 1 ml and Imipramine together can evidently cause an interaction, it can be taken if your doctor has suggested it. It's important to monitor your blood pressure regularly. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, throbbing headache, tremor, or palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Epitrate Injection 10 x 1 ml:
Taking Labetalol along with Epitrate Injection 10 x 1 ml can reduce the effects of Epitrate Injection 10 x 1 ml.

How to manage the interaction:
Taking Labetalol and Epitrate Injection 10 x 1 ml together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Epitrate Injection 10 x 1 ml when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[OPHTHALMIC SURGICAL AIDS]

FAQs

Epitrate Injection 10 x 1 ml is used for irrigation during intraoperative mydriasis (pupil dilation during surgery).
Epitrate Injection 10 x 1 ml contains Adrenaline and Sodium Metabisulphite. It works by constricting blood vessels and maintaining pupil dilation during eye surgery. Thereby, it ensures a stable surgical environment throughout the procedure.
The side effects of Epitrate Injection 10 x 1 ml include nausea and vomiting, increased heart rate and high blood pressure. Consult the doctor if any of these side effects persist or worsen.
Epitrate Injection 10 x 1 ml may cause nausea as a common side effect. If you experience this symptom, drink ginger or peppermint tea, avoid strong odours, get some fresh air, and avoid heavy, fatty and greasy foods.
No, do not self-administer Epitrate Injection 10 x 1 ml. It will be administered by the doctor.
Yes, in an emergency, you can inject this medicine directly through your pants or clothing into your outer thigh. Talk to your doctor to practice the technique.
You must call emergency services or go to the nearest emergency room right away, even if you feel completely better, because the allergic reaction can return as the medicine wears off. Talk to your doctor or pharmacist for more information.
No, you should not store it in your car, as extreme heat or cold can ruin the medicine and make it ineffective during an emergency. Talk to your pharmacist about proper carrying cases.
Check the viewing window on your device; if the liquid is cloudy, pinkish, brownish, or has floating particles, it has gone bad and must be replaced. Talk to your pharmacist to get a replacement.
Accidental injection into fingers or hands can severely restrict blood flow to that area and requires immediate medical attention at an emergency room. Talk to your doctor or pharmacist about safe handling.
In a life-threatening allergic emergency, this medicine is safe and essential to use because a severe reaction can harm both you and your baby. Talk to your doctor to discuss your emergency plan during pregnancy.
No, each injection device is designed for a single use only and must be disposed of safely after one injection. Talk to your doctor or pharmacist about how to get a replacement device.
Yes. Always seek emergency medical care after using adrenaline, even if your symptoms improve. Allergic symptoms can return after the first reaction, and healthcare professionals need to monitor you and decide whether additional treatment is required.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

1002-1003, 10th Floor, Windfall, Sahar Plaza, J.B.Nagar, Andheri-Kurla Road, Andheri (East), Mumbai-400059. Maharashtra, India.
Other Info - EPI0077
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