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compositionComposition:VALETHAMATE BROMIDE-8MG
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Prescription Medicine
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Epidosin 8 Injection 1 ml is used to treat spasms in the intestine and cervix. It contains Valethamate bromide, an anticholinergic drug that works by blocking the effect of acetylcholine (constricts muscle). It dilates the smooth muscles present in the intestine and cervix. Thus, it treats spasms. Common side effects of Epidosin 8 Injection 1 ml are headache, stomach upset, blurred vision, constipation, difficulty swallowing, injection site reactions and irregular heart rate.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

VALETHAMATE BROMIDE-8MG

Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Epidosin 8 Injection 1 ml

Epidosin 8 Injection 1 ml is a prescription injection primarily used to help the cervix dilate, or open up, during the active stage of childbirth. It is also used to relieve painful, sudden spasms in the muscles of the stomach, intestines, and urinary tract. By relaxing these smooth muscles, it helps ease delivery and reduces severe cramp-like pain.

Because this medicine is given as an injection, it does not have a standard daily home schedule. Instead, a healthcare professional will inject it when needed during active labour or during an acute episode of muscle spasm. You do not need to worry about taking it with food, but staying hydrated with clear fluids during labour can help support your overall comfort and energy levels.

Like many medications, Epidosin 8 Injection 1 ml can cause some mild side effects, such as a dry mouth, temporary blurry vision, or a slightly faster heartbeat. If you experience any severe symptoms, such as chest pain or an inability to pass urine, you must tell your medical team immediately so they can assist you.

Before you receive this injection, your healthcare team will review your medical history. Do not take this if you have certain eye conditions like glaucoma, an enlarged prostate, a blockage in your stomach or intestines, or severe heart problems. Sharing your full health history ensures this medication is safe for you.

Some medicines, especially those for depression, allergies, or cold symptoms, can interact with Epidosin 8 Injection 1 ml and increase the risk of dry mouth and dizziness. Avoid drinking alcohol around the time of treatment, as it can worsen drowsiness. If you are pregnant (outside of active labour), breastfeeding, or an elderly individual, talk to your doctor or pharmacist to discuss the risks and benefits.

Uses of Epidosin 8 Injection 1 ml

Epidosin 8 Injection 1 ml is used in the treatment of spasms of the cervix and intestine. The detailed uses of Epidosin 8 Injection 1 ml are as follows:

  • Slow cervical dilation during labour: It helps relax the muscles of the cervix, allowing it to open more smoothly and shortening the overall time of delivery.
  • Severe stomach and intestinal spasms: It relaxes the muscles of the digestive tract to relieve painful abdominal cramps, colic, and spasms.
  • Urinary tract spasms: It helps quiet overactive or cramping muscles in the urinary tract, easing the pain associated with bladder spasms.

Key Benefits

Epidosin 8 Injection 1 ml helps relieve smooth muscle spasms and may assist cervical dilatation during labour in selected clinical settings. The following are the benefits of this :

  • May help shorten the first stage of labour by promoting cervical relaxation when used as part of obstetric management.
  • Helps relieve painful spasms of smooth muscle in the gastrointestinal, biliary, or urinary tracts.
  • Provides rapid symptom relief when administered by injection, making it useful when quick control of spasms is needed.
  • May reduce discomfort associated with muscle spasms, allowing you to rest more comfortably during recovery.

Directions for Use

  • Your doctor will determine the dosage and frequency depending on your condition.
  • Epidosin 8 Injection 1 ml will be administered by a healthcare professional.
  • Do not self-administer.

How Epidosin 8 Injection 1 ml Works

Epidosin 8 Injection 1 ml belongs to a group of medicines called antispasmodics or anticholinergics. It works by blocking the action of acetylcholine, a natural chemical messenger in the body that signals muscles to tighten or contract. When injected, the medicine specifically targets the smooth muscles of the cervix, digestive system, and urinary tract. By blocking the contracting signals, it allows these muscles to relax. In labour, this relaxation helps the cervix widen more easily; in spasm conditions, it stops the sudden, painful cramping of internal organs.
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Alcohol

Caution

Consumption of alcohol may worsen the underlying condition that causes spasms. Hence, avoid alcohol consumption while on treatment with this medicine.

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Pregnancy

Caution

Epidosin 8 Injection 1 ml should be used in pregnancy only if clinically needed. Please consult your doctor. Your doctor will weigh the benefits and any potential risks before prescribing this medicine.

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Breast Feeding

Caution

Epidosin 8 Injection 1 ml should be used in breastfeeding only if clinically needed. Please consult your doctor. Your doctor will weigh the benefits and any potential risks before prescribing this medicine.

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Driving

Caution

Epidosin 8 Injection 1 ml may cause vision problems. So, do not drive or operate heavy machinery after receiving Epidosin 8 Injection 1 ml until your vision improves.

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Liver

Caution

Epidosin 8 Injection 1 ml should be used with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust the dose based on your condition.

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Kidney

Caution

Epidosin 8 Injection 1 ml to be taken with caution, especially if you have a history of Kidney diseases/conditions. Your doctor may adjust the dose based on your condition.

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Children

Consult your doctor

Consult your doctor. Your doctor will weigh the benefits and risks before prescribing this medicine for your child.

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Heart

Caution

Epidosin 8 Injection 1 ml should be used cautiously in heart patients due to its anticholinergic effects, which may alter heart rate. Always consult your doctor before use to avoid potential cardiac complications.

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Geriatrics

Caution

Geriatric patients may receive Epidosin 8 Injection 1 ml, but only with caution due to increased sensitivity to anticholinergic effects. Close monitoring is essential to avoid complications like confusion or heart rate changes.

What if I have taken an overdose of Epidosin 8 Injection 1 ml

Because a trained professional gives this injection, an overdose is rare. However, if you receive too much, symptoms may include severe dry mouth, extreme thirst, blurred vision, a rapid heart rate, or confusion. The medical staff will monitor you closely and treat any symptoms immediately. If you suspect an issue, alert your doctor or nurse right away.

Diet & Lifestyle Advise

  • Sip water frequently: Since dry mouth is a very common side effect, keeping small sips of water nearby can help keep your mouth comfortable.
  • Rest your eyes: If you experience temporary blurry vision, avoid reading, looking at screens, or bright lights until your vision returns to normal.
  • Eat light, simple foods: If you are receiving this for stomach spasms, stick to bland, easy-to-digest foods like toast, rice, or crackers once your doctor says it is safe to eat.
  • Stay in a cool environment: This medicine can reduce your body's ability to sweat, making it easier to overheat. Avoid hot baths or warm rooms immediately after your injection.
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How Soon It Starts Working

The time required for Epidosin 8 Injection 1 ml to start to work: Epidosin 8 Injection 1 ml shows its action within 20 to 30 minutes of IM administration. The time for which the effects of Epidosin 8 Injection 1 ml last: The duration of Epidosin 8 Injection 1 ml’s effect is clinically not established.

What if you forget to take Epidosin 8 Injection 1 ml

Since this medicine is given by a medical professional in a hospital or clinic setting when needed, it is highly unlikely that you will miss a dose. If you have concerns about the timing of your injection, speak directly to your healthcare team.

Storage

• Store the injection vials or ampoules at room temperature, ideally below 30°C.

Drug Warnings

  • Visual inspection: Before the injection is given, ensure the solution is clear, colourless, and free of any visible floating particles. Do not use if the liquid is discoloured.
  • Avoid driving: Do not drive, operate machinery, or perform tasks that require clear vision until you are sure your vision is completely back to normal.
  • Monitor injection sites: Check the area where you were injected for signs of pain, swelling, or redness, and inform your nurse if these symptoms worsen.
  • Overheating risk: Be cautious in hot weather, as this medication reduces sweating and can increase your risk of heatstroke.

Drug-Drug Interactions

verifiedApollotooltip
  • Antihistamines and cold medicines (e.g., chlorpheniramine, diphenhydramine): Taking these alongside Epidosin 8 Injection 1 ml can significantly increase side effects like dry mouth, blurry vision, and difficulty urinating.
  • Tricyclic antidepressants (e.g., amitriptyline, imipramine): Combining these can amplify the anticholinergic effects, leading to a faster heart rate and severe constipation.
  • Medicines that speed up gut movement (e.g., metoclopramide): Epidosin 8 Injection 1 ml can oppose and reduce the effectiveness of these gut-stimulating medications.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • No clinically significant food interactions are known with Epidosin 8 Injection 1 ml.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTISPASMODICS]

FAQs

Epidosin 8 Injection 1 ml is used to treat Spasms of the intestine and cervix.
Epidosin 8 Injection 1 ml reduces the spasms associated with various conditions. It works by relaxing the smooth muscles by inhibiting the action of acetylcholine (a chemical that causes spasms or muscle contractions).
Epidosin 8 Injection 1 ml does not treat kidney stones. It can only reduce the abdominal pain associated with this condition.
Epidosin 8 Injection 1 ml is used to relieve spasms of the smooth muscles, including spasms of the intestine and cervix. During labour, it may be given as an injection to relax the cervical muscles, helping the cervix dilate more easily and potentially shortening the duration of childbirth. Your doctor will decide if it is appropriate for your delivery plan.
The common side-effects of Epidosin 8 Injection 1 ml are dry mouth, blurred vision, difficulty swallowing or talking, constipation, urinary retention, irregular heart rate and injection site reactions. These side effects usually do not require any medical attention.
As it is a parenteral dosage form, there will be a less or negligible chance of missing a dose. However, if any dose is missed, inform your doctor immediately. But do not self-administer.
Before receiving Epidosin 8 Injection 1 ml, tell your doctor about your complete medical and surgical history, especially if you have glaucoma, heart, liver or kidney disease, urinary problems, intestinal blockage, seizures, or if you are pregnant, planning pregnancy, or breastfeeding. Also inform your doctor about all prescription medicines, over-the-counter medicines, herbal products, and supplements you take, as they may interact with Epidosin 8 Injection 1 ml.
Epidosin 8 Injection 1 ml contains Valethamate bromide as its active ingredient.
Epidosin 8 Injection 1 ml is administered by a trained healthcare professional in a hospital or clinic. It is given as an injection into a muscle (intramuscular) or slowly into a vein (intravenous). Do not self-administer. If you have questions about how it will be given, talk to your doctor.
Epidosin 8 Injection 1 ml is contraindicated in people with benign prostatic hyperplasia (prostate enlargement), narrow angle glaucoma, pyloric stenosis, paralytic ileus (paralysis of intestinal muscles), megacolon, ulcerative colitis (inflammation and ulcers in the lining of the large intestine), tachyarrhythmia (fast heart rate), severe kidney and liver impairment.
Yes, Epidosin 8 Injection 1 ml may interact with other medicines such as antihistamines, phenothiazide antipsychotics, medications used to treat nausea and vomiting (domperidone and metoclopramide) and medicine used to treat Parkinson’s disease. Therefore, let your doctor know about all the medications you are taking.
Store Epidosin 8 Injection 1 ml below 30°C. Protect from light and moisture. Do not freeze. Keep it out of reach of children.
Yes, dry mouth is a very common side effect because the medicine temporarily reduces salivary secretions. Sipping small amounts of water can help relieve this discomfort. Talk to your doctor if it becomes bothersome.
It is not fully known if this medicine passes into breast milk. It may also temporarily reduce milk production. Talk to your doctor or pharmacist to weigh the benefits and risks before using it while breastfeeding.
It can cause temporary blurry vision or difficulty focusing. This is temporary and will wear off as the medicine leaves your system. Avoid driving or reading in bright light until your vision is clear, and talk to your doctor if you are concerned.
Yes, it is highly effective at relaxing the smooth muscles of the digestive tract to relieve severe, painful spasms and colic. Talk to your doctor to see if this is the right option for your symptoms.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase Iii, New Delhi - 110020.
Other Info - EPI0002
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