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  3. Epalridase 50 mg Tablet 10's

Epalridase 50 mg Tablet 10's, Pack of 10 TabletS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Epalridase 50 mg Tablet is used to treat diabetic neuropathy (diabetic nerve pain). It contains Epalrestat which prevents the accumulation of sorbitol that leads to nerve pain. In some cases, this medicine may cause side effects such as nausea, vomiting, diarrhoea, dizziness, and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

EPALRESTAT-50MG

Manufacturer/Marketer :

East West Pharma India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Epalridase 50 mg Tablet

Epalridase 50 mg Tablet is used to manage diabetic neuropathy. Diabetic neuropathy is a chronic progressive nerve disease which causes nerve pain due to nerve damage in diabetic patients. It mostly affects the legs and feet.

Epalridase 50 mg Tablet contains ‘Epalrestat’ that works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes, which leads to nerve pain. Epalridase 50 mg Tablet prevents the accumulation of sorbitol. Thus, it helps in treating diabetic neuropathy.

Take Epalridase 50 mg Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as nausea, vomiting, diarrhoea, dizziness, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking Epalridase 50 mg Tablet if you are pregnant or breastfeeding. Epalridase 50 mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Epalridase 50 mg Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Epalridase 50 mg Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Epalridase 50 mg Tablet

Treatment of Diabetic neuropathy (diabetic nerve pain).

Directions for Use

• Epalridase 50 mg Tablet should be taken before meals.• It is usually taken 3 times a day, at the same time each day, or as prescribed by your doctor.• Swallow Epalridase 50 mg Tablet as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Epalridase 50 mg Tablet belongs to a group of medicines called aldose reductase inhibitors. Epalridase 50 mg Tablet is used to manage diabetic neuropathy. Epalridase 50 mg Tablet works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes, which leads to nerve pain. Epalridase 50 mg Tablet prevents sorbitol accumulation, thereby treating diabetic neuropathy (pain due to nerve damage).

How Epalridase 50 mg Tablet Works

Epalridase 50 mg Tablet contains ‘Epalrestat’ that works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes, which leads to nerve pain. Epalridase 50 mg Tablet prevents the accumulation of sorbitol. Thus, it helps in treating diabetic neuropathy.

Storage

Keep Epalridase 50 mg Tablet out of reach and sight of children.
Side effects of Epalridase 50 mg Tablet
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Managing Medication-Related Skin Allergies: A Step-by-Step Guide
  • If you experience signs of skin allergies such as redness, itching, or irritation after taking medication, contact your doctor right away.
  • To alleviate skin allergy symptoms, your doctor may change your medication regimen or offer tailored medication management advice.
  • Your doctor may recommend or prescribe drugs to relieve discomfort.
  • Cool compresses or calamine lotion can help relieve redness and itching on the afflicted skin area.
  • Staying hydrated by consuming plenty of water can help relieve discomfort.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

What if I have taken an overdose of Epalridase 50 mg Tablet

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Do not take Epalridase 50 mg Tablet if you are allergic to any of its contents. Inform your doctor if you have liver or kidney problems. Consult your doctor before taking Epalridase 50 mg Tablet if you are pregnant or breastfeeding. Epalridase 50 mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Epalridase 50 mg Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Epalridase 50 mg Tablet as it could lead to increased drowsiness and sleepiness.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.

  • Include cayenne pepper in your diet as it can help lower neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain. 

  • Rest well, get plenty of sleep.

  • Try taking a warm bath as it can be soothing.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Epalridase 50 mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Epalridase 50 mg Tablet as it may cause increased dizziness.

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Pregnancy

Caution

Limited information is available regarding the use of Epalridase 50 mg Tablet in pregnant women. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Limited information is available regarding the use of Epalridase 50 mg Tablet in breastfeeding women. Consult your doctor before taking Epalridase 50 mg Tablet ; your doctor will decide whether Epalridase 50 mg Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Epalridase 50 mg Tablet may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Epalridase 50 mg Tablet should not be used in patients with severe liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Epalridase 50 mg Tablet should be used with caution in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Epalridase 50 mg Tablet should not be given to children as safety and efficacy have not been established.

Have a query?

FAQs

Epalridase 50 mg Tablet is used to manage diabetic neuropathy, a chronic progressive nerve disease which causes nerve pain due to nerve damage in diabetic patients.

Epalridase 50 mg Tablet works by inhibiting aldose reductase enzyme which catalyses the conversion of glucose to sorbitol. Epalridase 50 mg Tablet prevents the accumulation of sorbitol, thereby helps in treating diabetic neuropathy.

Diarrhoea could be a side-effect of Epalridase 50 mg Tablet . Drink plenty of fluids to prevent dehydration and consume non-spicy meals if you experience diarrhoea. Consult your doctor if you have severe diarrhoea.

Epalridase 50 mg Tablet might cause high blood pressure. So, if you have hypertension, consult your doctor before taking Epalridase 50 mg Tablet . Regularly monitor blood pressure levels while taking Epalridase 50 mg Tablet .

Do not discontinue Epalridase 50 mg Tablet without consulting your doctor. To treat your condition effectually, continue taking Epalridase 50 mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Epalridase 50 mg Tablet .

Epalridase 50 mg Tablet may cause peripheral oedema. Peripheral oedema is the swelling of the hands and lower legs. Avoid sitting or standing for too long. Raise your legs by putting a pillow under the legs while lying down.

Epalridase 50 mg Tablet contains epalrestat, which is classified as an Aldose Reductase Inhibitor. It is used for the treatment of diabetic neuropathy.

Some individuals may experience specific common side effects, such as nausea, vomiting, diarrhoea, dizziness, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Follow your doctor's advice and take the right amount of medicine. Be aware of side effects and take care of yourself. If you're pregnant while on treatment, inform your doctor immediately. Don't take other medications unless instructed by the doctor. Alcohol consumption should be avoided. By following these precautions, you'll benefit most from your medicine and stay safe.

In some individuals, Epalridase 50 mg Tablet may cause vomiting as it is a common side effect of Epalridase 50 mg Tablet . This effect does not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Limited information is available regarding the use of Epalridase 50 mg Tablet in pregnant women. Please consult your doctor if you are pregnant or planning to become pregnant before taking Epalridase 50 mg Tablet , your doctor will prescribe only if the benefits outweigh the risks.

It is best to consult your doctor before taking any other medicines with Epalridase 50 mg Tablet , as some medications may interact with it. Inform your doctor about all the medicines you're currently taking to ensure safe and effective treatment.

Country of origin

INDIA

Manufacturer/Marketer address

No. 10, 2nd Cross, Maravaneri, Salem - 636007, Tamil Nadu.
Other Info - EPA0009

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:47 AM IST

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Reference

  1. https://www.mims.com/malaysia/drug/info/epalrestat?mtype=generic
  2. https://www.medindia.net/doctors/drug_information/epalrestat.htm

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