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compositionComposition:ENALAPRILAT-1.25MG
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Prescription Medicine
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Envas Injection 1 ml is used to treat hypertension when oral treatment is not effective. It contains Enalaprilat, which works by decreasing the production of certain substances responsible for increased blood pressure. Envas Injection 1 ml may cause side effects such as cough, dizziness, headache, nausea, light-headedness, difficulty breathing, vomiting, confusion, sore throat, chest pain, abdominal pain, diarrhoea, decreased blood pressure, nervousness, injection site reactions, and hoarseness.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ENALAPRILAT-1.25MG

Manufacturer/Marketer :

Cadila Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Envas Injection 1 ml

Envas Injection 1 ml is a prescription medication given by injection to treat severe high blood pressure, especially when oral medications are not suitable or cannot be taken. It belongs to a group of medicines that help relax blood vessels, making it easier for the heart to pump blood throughout the body.

Because this medication is injected directly into a vein, it is typically given at regular intervals under the close supervision of a healthcare provider in a hospital or clinic. While food does not affect how this medicine is absorbed, making healthy diet and lifestyle changes, such as reducing salt intake and managing stress, is essential to achieve the best long-term results for your blood pressure.

While taking this medicine, some people may experience mild side effects like dizziness, lightheadedness, or a dry cough. However, you must contact your doctor immediately if you experience serious side effects, such as swelling of your face, lips, tongue, or throat, which can make breathing difficult.

Do not take this if you have a history of severe allergic reactions (angioedema) to similar blood pressure medications, or if you are pregnant. Before receiving this medicine, talk to your doctor if you have kidney disease, diabetes, or a history of heart problems.

This medication can interact with other blood pressure drugs, lithium, and potassium supplements. Drinking alcohol while receiving this treatment can cause a sudden, severe drop in blood pressure. If you are pregnant, breastfeeding, or an older adult, consult your doctor to ensure this treatment is safe for you.

Uses of Envas Injection 1 ml

Envas Injection 1 ml is used to treat severe high blood pressure. The detailed uses of Envas Injection 1 ml are as follows: 

  • Severe high blood pressure: Envas Injection 1 ml helps rapidly lower blood pressure when quick control is necessary and oral medications are not an option.
  • Hypertensive emergencies: It is used in critical hospital situations to quickly reduce dangerously high blood pressure, protecting vital organs from damage.

Key Benefits

Envas Injection 1 ml helps rapidly lower dangerously high blood pressure in emergency and hospital settings. When administered under medical supervision, it provides fast blood pressure control, protects vital organs, and supports safe recovery during acute medical conditions.

  • Provides Rapid Blood Pressure Control: Because this medicine is given directly into the bloodstream, it begins working within minutes to quickly lower dangerously high blood pressure when immediate treatment is needed.
  • Protects the Heart and Vital Organs: By reducing blood pressure promptly, this medicine helps decrease the workload on the heart and lowers the risk of serious complications such as stroke, heart attack, and damage to other vital organs.
  • Useful When Oral Medicines Cannot Be Taken: This injectable treatment is an effective option for patients who are unable to swallow tablets due to surgery, severe illness, or unconsciousness, ensuring reliable blood pressure control in a monitored medical setting.
Side effects of Envas Injection 1 ml
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Envas Injection 1 ml is administered by the doctor or healthcare professional.
  • Do not self-administer.

How Envas Injection 1 ml Works

Envas Injection 1 ml contains enalaprilat, which works by blocking a specific natural substance in the body that causes blood vessels to tighten and narrow. By preventing this substance from working, the medicine allows the blood vessels to relax and widen. This widening reduces the pressure inside the vessels, making it much easier for blood to flow and allowing your heart to pump more efficiently.
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Alcohol

Unsafe

Do not consume alcohol while on treatment with Envas Injection 1 ml as it may worsen the side effects like dizziness and also may increase blood pressure.

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Pregnancy

Unsafe

The use of Envas Injection 1 ml is contraindicated during the second and third trimester of pregnancy. It may cause harm to the developing fetus. Inform your doctor if you are pregnant before receiving Envas Injection 1 ml.

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Breast Feeding

Unsafe

Envas Injection 1 ml may be excreted in human milk. Therefore, it is not recommended for breastfeeding mothers as it may be unsafe for the baby. Inform your doctor if you are breastfeeding before receiving Envas Injection 1 ml. Your doctor will decide whether you stop breastfeeding or discontinue the use of Envas Injection 1 ml based on the benefits and risks.

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Driving

Caution

Envas Injection 1 ml may cause dizziness. Hence, do not drive or operate machines after receiving this medicine.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Envas Injection 1 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition. Elderly patients with liver impairment should start the treatment with a lower dose.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Envas Injection 1 ml. Envas Injection 1 ml may cause renal failure in some patients. Hence, inform your doctor if the patient develops any symptoms. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition. Elderly patients with renal impairment should start the treatment with a lower dose.

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Children

Unsafe

Envas Injection 1 ml is not recommended for use in children as the safety and efficacy are not established for this age group.

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Heart

Caution

Envas Injection 1 ml should be avoided in individuals with heart problems unless specifically advised by a doctor, as it may lead to complications like low blood pressure or kidney issues. Always seek medical guidance before use.

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Geriatrics

Caution

Envas Injection 1 ml should be used cautiously in geriatric patients, as age-related kidney or cardiovascular changes may increase the risk of side effects like low blood pressure or impaired kidney function. Always consult your doctor to determine if it's appropriate for your condition.

What if I have taken an overdose of Envas Injection 1 ml

If you suspect an overdose, or if you experience severe dizziness, confusion, or fainting, seek emergency medical help.

Diet & Lifestyle Advise

  • Eat a low-sodium diet to help keep your blood pressure within a healthy, stable range.
  • Avoid using salt substitutes that contain potassium, as this medicine can naturally raise potassium levels in your blood to unsafe levels.
  • Stay adequately hydrated, but consult your doctor about your daily fluid limits if you have a history of heart or kidney issues.
  • Avoid drinking alcohol, as it can combine with the medication to cause an unsafe drop in blood pressure.
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How Soon It Starts Working

The time required for Envas Injection 1 ml to start to work: Envas Injection 1 ml ideally shows its action within 15 minutes after administration. The time for which the effects of Envas Injection 1 ml last: The effect of Envas Injection 1 ml lasts for 6 hours.

What if you forget to take Envas Injection 1 ml

Since this medication is usually given by a healthcare provider in a hospital or clinic, a missed dose is unlikely. If you are receiving this treatment at home and miss a scheduled dose, contact your doctor or pharmacist immediately for instructions. Do not double the dose to make up for a missed one.

Storage

• Store Envas Injection 1 ml vials at room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Always inspect the liquid inside the vial before use. It should be clear and colourless. Do not use the medicine if it looks cloudy, discoloured, or contains visible particles.
  • If injecting at home, safely discard used needles and syringes in an approved sharps disposal container. Never reuse needles.
  • To prevent dizziness or falls, rise very slowly when standing up from a sitting or lying position.
  • Monitor your blood pressure daily and keep a log to share with your healthcare team at your next appointment.
  • Do not take this medicine if you are pregnant, as it can cause severe harm or death to an unborn baby. Use reliable birth control and tell your doctor immediately if you think you might be pregnant.

Drug-Drug Interactions

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  • Other blood pressure medications: Combining these can cause your blood pressure to drop too low.
  • Potassium supplements or potassium-sparing water pills: May cause dangerously high levels of potassium in your blood.
  • Lithium: This medicine can raise lithium levels in your body, increasing the risk of lithium toxicity.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs): May reduce the effectiveness of Envas Injection 1 ml and increase the risk of severe kidney damage.

Drug-Drug Interactions

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How does the drug interact with Envas Injection 1 ml:
Using aliskiren together with Envas Injection 1 ml may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood.

How to manage the interaction:
Taking Envas Injection 1 ml with aliskiren is not recommended, but it can be taken together if your doctor advises. However, contact your doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, or feelings of heaviness in the legs. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Envas Injection 1 ml:
Coadministration of Envas Injection 1 ml with Spironolactone may increase the risk of hyperkalemia (high potassium levels in the blood), hypotension, syncope (fainting), and renal failure due to additive or synergistic effects. If you are elderly, dehydrated, or have a history of renal or heart illness, your risk is enhanced.

How to manage the interaction:
Although taking Envas Injection 1 ml together with Spironolactone may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, coconut water, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Envas Injection 1 ml:
Envas Injection 1 ml combined with Trimethoprim can cause hyperkalemia by elevating blood potassium levels. In severe cases, hyperkalemia can induce muscle paralysis, renal damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of renal or cardiovascular disease.

How to manage the interaction:
Although taking Envas Injection 1 ml together with Trimethoprim may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
EnalaprilPotassium citrate
Severe
How does the drug interact with Envas Injection 1 ml:
Taking potassium citrate with Envas Injection 1 ml may increase potassium levels in the blood, leading to kidney problems, muscle paralysis, and abnormal heart rhythm.

How to manage the interaction:
Co-administration of Envas Injection 1 ml with Potassium citrate can result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Envas Injection 1 ml:
Combine use of Envas Injection 1 ml and Valsartan can increase the effect of Valsartan.

How to manage the interaction:
Although taking Envas Injection 1 ml together with Valsartan may result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat, contact a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Envas Injection 1 ml:
Coadministration of Envas Injection 1 ml with Telmisartan may increase the risk of hyperkalemia (high potassium levels in the blood), hypotension, syncope (fainting), and renal failure due to additive or synergistic effects. If you are elderly, dehydrated, or have a history of renal or heart illness, your risk is enhanced.

How to manage the interaction:
Although taking Envas Injection 1 ml together with Telmisartan may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, papayas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Envas Injection 1 ml:
Coadministration of Allopurinol with Envas Injection 1 ml may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Allopurinol and Envas Injection 1 ml, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also, let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not stop using any medications without consulting your doctor.
EnalaprilPotassium iodide
Severe
How does the drug interact with Envas Injection 1 ml:
Taking Envas Injection 1 ml with Potassium iodide increases the potassium levels in the blood, which may lead to hyperkalemia. In severe cases, hyperkalemia may lead to muscular paralysis, kidney damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Envas Injection 1 ml together with Potassium iodide may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, coconut and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
EnalaprilPotassium citrate
Severe
How does the drug interact with Envas Injection 1 ml:
Taking Envas Injection 1 ml with Potassium citrate increases the potassium levels in the blood, which may lead to hyperkalemia. In severe cases, hyperkalemia may lead to muscular paralysis, kidney damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Envas Injection 1 ml together with Potassium citrate may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Envas Injection 1 ml:
Using Envas Injection 1 ml together with Irbesartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Irbesartan with Envas Injection 1 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, and feelings of heaviness in your legs. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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  • Potassium-rich salt substitutes: Can lead to abnormally high blood potassium levels, which may affect heart rhythms.

ENALAPRILAT-1.25MGPotassium rich foods
Moderate

Drug-Food Interactions

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ENALAPRILAT-1.25MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consuming a high-potassium diet while taking Envas Injection 1 ml can cause hyperkalemia (elevated blood potassium levels). Hyperkalemia may lead to dizziness, lightheadedness, fainting, or a rapid heartbeat. Avoid the consumption of potassium-rich foods.

Habit Forming

No

Therapeutic Class

[ACE INHIBITORS]

FAQs

Envas Injection 1 ml is used to treat hypertension.
Envas Injection 1 ml contains Enalaprilat, which works by reducing the production of certain substances that cause an increase in blood pressure. This allows the blood to flow more smoothly and makes the heart more efficient at pumping blood throughout the body.
It is advised to continue your medicine even after your blood pressure is controlled or becomes normal, as it can shoot up at any time. If you have a persistent headache, please consult your doctor immediately.
The chances of missing a dose of Envas Injection 1 ml are very low. If you forget to take a dose or miss the appointment, consult your doctor and receive your next dose on time.
It is given as an injection or infusion directly into a vein, typically by a healthcare provider in a clinic or hospital setting. Talk to your doctor.
No, this medicine should not be used during pregnancy as it can cause serious injury or death to an unborn baby. Talk to your doctor.
This medicine blocks certain enzymes, which can lead to a buildup of natural substances in your respiratory tract that trigger a dry, tickling cough. Talk to your doctor.
It is highly recommended to avoid alcohol, as it can interact with the medicine to cause severe dizziness, lightheadedness, or fainting. Talk to your doctor.
Sit or lie down immediately to avoid falling. Avoid sudden movements, and let your healthcare provider know right away. Talk to your doctor.
You should avoid salt substitutes containing potassium, as they can cause your blood potassium levels to rise dangerously high when combined with this medicine. Talk to your doctor.

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Country of origin

India

Manufacturer/Marketer address

Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.
Other Info - ENV0003
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