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  3. Emesafe 2Mg Oral Spray 15Ml

Emesafe 2Mg Oral Spray 15Ml, Pack of 1 Spray
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Emesafe 2Mg Oral Spray is used in the prevention of vomiting and nausea that usually occur after cancer chemotherapy, radiation treatment, or surgery. It contains ondansetron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. It may cause common side effects such as constipation, headache, diarrhea, drowsiness, flushing (a feeling of warmth), weakness, and tiredness. Before taking this medication, inform your doctor if you are allergic to any of its components.

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Composition :

ONDANSETRON-2MG

Manufacturer/Marketer :

Wallace Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Emesafe 2Mg Oral Spray

Emesafe 2Mg Oral Spray is primarily used in the prevention of vomiting and nausea. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is the natural response of the body to expel the stomach contents from the mouth forcefully.

Emesafe 2Mg Oral Spray contains Ondansetron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting.

You may experience common side effects such as constipation, headache, diarrhea, drowsiness, flushing (a feeling of warmth), weakness, and tiredness. If the side effects persist or worsen, please consult your doctor.

Before using Emesafe 2Mg Oral Spray, inform your doctor if you are allergic to any of its ingredients. Emesafe 2Mg Oral Spray should be used during pregnancy and breastfeeding only if prescribed by a doctor.

Uses of Emesafe 2Mg Oral Spray

Emesafe 2Mg Oral Spray is used in the prevention of Nausea and Vomiting. The detailed uses of Emesafe 2Mg Oral Spray are as follows:

  • Chemotherapy-Induced Nausea and Vomiting: Emesafe 2Mg Oral Spray is frequently prescribed to alleviate nausea and vomiting caused by chemotherapy treatments.
  • Radiation Therapy Support: Emesafe 2Mg Oral Spray can help manage nausea and vomiting experienced by patients undergoing radiation therapy, improving treatment tolerance.
  • Postoperative Nausea and Vomiting Relief: Many patients experience nausea or vomiting after surgical procedures, and Emesafe 2Mg Oral Spray is effective in controlling and reducing these symptoms.

Have a query?

Directions for Use

  • Emesafe 2Mg Oral Spray can be taken with or without food, as advised by the doctor.
  • Typically, it is taken twice daily. However, follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow the tablet as a whole with a glass of water.
  • Do not crush, chew, break, or open it.

Medicinal Benefits

  • Emesafe 2Mg Oral Spray is an antiemetic medication primarily used to prevent and treat nausea and vomiting associated with conditions such as cancer chemotherapy, radiation treatment, and surgery.
  • When serotonin levels increase in the blood, it stimulates the CTZ receptor (chemoreceptor trigger zone) located in the brain, which is responsible for controlling nausea and vomiting.
  • Emesafe 2Mg Oral Spray contains Ondansetron, which works by inhibiting the release of serotonin, thereby preventing nausea and vomiting.

How Emesafe 2Mg Oral Spray Works

Emesafe 2Mg Oral Spray contains Ondansetron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. As a result, Emesafe 2Mg Oral Spray prevents the sensation of nausea and vomiting caused by conditions like surgery, cancer chemotherapy, pregnancy, or motion sickness.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Emesafe 2Mg Oral Spray 15Ml
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Contact your physician right away if you suffer from hypoxia symptoms including chest pain, disorientation, or shortness of breath.
  • Your doctor can monitor your progress and modify treatment programs with the help of routine follow-up sessions.
  • Omega-3 supplements may support the transport of oxygen to tissues.
  • Regular exercise improves cardiovascular health and boosts oxygen delivery to tissues.
  • Quit smoking, as it can worsen hypoxia.

What if I have taken an overdose of Emesafe 2Mg Oral Spray

Do not take more than the prescribed dose of Emesafe 2Mg Oral Spray, as it may lead to an overdose. Symptoms of an overdose may include sudden loss of vision for a short time, irregular heartbeat, constipation, fainting, dizziness, or light-headedness. If you suspect that you have taken an overdose of this medication or notice any unusual symptoms, please consult a doctor immediately.

Drug Warnings

  • Do not use Emesafe 2Mg Oral Spray if you are allergic to any of its ingredients.
  • Avoid using Emesafe 2Mg Oral Spray if you are taking apomorphine (a medicine used to treat Parkinson's disease), as it may cause a sharp drop in blood pressure and even fainting.
  • Inform your doctor before using Emesafe 2Mg Oral Spray if you have any medical conditions, such as severe constipation, bowel obstruction, depression, electrolyte imbalance, heart or blood vessel problems (such as irregular heartbeats and high blood pressure), diabetes, liver problems, or a history of tonsils or adenoid removal surgery.
  • Tell your doctor if you are taking any medications for depression, as using them alongside Emesafe 2Mg Oral Spray may increase the risk of serotonin syndrome, a potentially life-threatening condition.
  • Emesafe 2Mg Oral Spray is not recommended for use during early pregnancy (first trimester), as it may increase the risk of birth defects in the mouth and face of the baby.
  • Avoid breastfeeding while taking Emesafe 2Mg Oral Spray, as small amounts of the medicine may pass into breast milk.
  • Avoid consuming alcohol while taking Emesafe 2Mg Oral Spray, as it may worsen the side effects like drowsiness.

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
OndansetronEfavirenz
Severe

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
How does the drug interact with Emesafe 2Mg Oral Spray 15Ml:
Taking Emesafe 2Mg Oral Spray 15Ml with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Emesafe 2Mg Oral Spray 15Ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronEfavirenz
Severe
How does the drug interact with Emesafe 2Mg Oral Spray 15Ml:
Taking Emesafe 2Mg Oral Spray 15Ml with efavirenz increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Emesafe 2Mg Oral Spray 15Ml along with efavirenz can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronMilnacipran
Severe
How does the drug interact with Emesafe 2Mg Oral Spray 15Ml:
When Emesafe 2Mg Oral Spray 15Ml, is taken with milnacipran it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Emesafe 2Mg Oral Spray 15Ml along with milnacipran can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronPanobinostat
Severe
How does the drug interact with Emesafe 2Mg Oral Spray 15Ml:
Taking Emesafe 2Mg Oral Spray 15Ml with Panobinostat increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Emesafe 2Mg Oral Spray 15Ml along with Panobinostat can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
OndansetronToremifene
Severe
How does the drug interact with Emesafe 2Mg Oral Spray 15Ml:
Taking Emesafe 2Mg Oral Spray 15Ml with toremifene increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Emesafe 2Mg Oral Spray 15Ml along with toremifene can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
OndansetronDuloxetine
Severe
How does the drug interact with Emesafe 2Mg Oral Spray 15Ml:
Taking Emesafe 2Mg Oral Spray 15Ml with duloxetine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in body).

How to manage the interaction:
Although taking Emesafe 2Mg Oral Spray 15Ml with duloxetine can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting a doctor.
OndansetronCeritinib
Severe
How does the drug interact with Emesafe 2Mg Oral Spray 15Ml:
Taking ceritinib together with Emesafe 2Mg Oral Spray 15Ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Emesafe 2Mg Oral Spray 15Ml along with ceritinib can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronProcarbazine
Severe
How does the drug interact with Emesafe 2Mg Oral Spray 15Ml:
When Emesafe 2Mg Oral Spray 15Ml, is taken with procarbazine it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Emesafe 2Mg Oral Spray 15Ml along with procarbazine can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronTramadol
Severe
How does the drug interact with Emesafe 2Mg Oral Spray 15Ml:
Co-administration of tramadol with Emesafe 2Mg Oral Spray 15Ml can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Taking Emesafe 2Mg Oral Spray 15Ml with tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OndansetronNaratriptan
Severe
How does the drug interact with Emesafe 2Mg Oral Spray 15Ml:
When Emesafe 2Mg Oral Spray 15Ml, is taken with naratriptan it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Emesafe 2Mg Oral Spray 15Ml along with naratriptan can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat small meals throughout the day and eat slowly to help digestion.
  • If you are sensitive to food smells, try eating cold or room-temperature foods instead of hot ones.
  • Avoid acidic foods or drinks like orange or grapefruit juice.
  • After your meals, rest with your head elevated about 12 inches above your head.
  • Drink liquids or water between meals rather than during meals.
  • Eat when you are least nauseated to help prevent discomfort.
  • Avoid consuming greasy or oily foods, as these foods can trigger nausea and vomiting.
  • Include clear broths, non-fat yoghurt, fruit juice, sherbet, and sports drinks for fluid makeup that has been lost due to vomiting.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Emesafe 2Mg Oral Spray Substitute

Substitutes safety advice
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Alcohol

Caution

Alcohol has no known direct interaction with Emesafe 2Mg Oral Spray. However, it is advisable to avoid consuming alcohol while taking Emesafe 2Mg Oral Spray, as it may worsen the side effects like drowsiness.

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Pregnancy

Unsafe

Emesafe 2Mg Oral Spray should be used during pregnancy only if prescribed by a doctor. It is generally not recommended for use during early pregnancy (first trimester), as it may increase the risk of birth defects in the mouth and face of the baby.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Emesafe 2Mg Oral Spray, as small amounts of the medicine may pass into breast milk.

bannner image

Driving

Caution

Emesafe 2Mg Oral Spray does not affect your ability to drive. However, if you experience drowsiness or blurred vision after taking Emesafe 2Mg Oral Spray, avoid driving or operating any heavy machinery.

bannner image

Liver

Caution

In individuals with liver problems, the use of Emesafe 2Mg Oral Spray is allowed if prescribed by a doctor. However, patients with severe liver impairment should take a low dose of Emesafe 2Mg Oral Spray as much as possible. Do not take more than 8 mg of Emesafe 2Mg Oral Spray per day in case of liver disease.

bannner image

Kidney

Safe if prescribed

The use of Emesafe 2Mg Oral Spray is considered safe in patients with kidney disorders. No dose adjustment is required.

bannner image

Children

Safe if prescribed

Emesafe 2Mg Oral Spray should not be given to children below 4 years of age, as its safety and effectiveness have not been established in this age group. The use of Emesafe 2Mg Oral Spray is safe in children above 4 years of age if prescribed by a doctor.

FAQs

Emesafe 2Mg Oral Spray is used in the prevention of vomiting and nausea that usually occur after cancer chemotherapy, radiation treatment, or surgery.

Emesafe 2Mg Oral Spray contains Ondansetron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting.

Emesafe 2Mg Oral Spray may cause drowsiness and changes in vision, so avoid driving or operating any machines that require mental alertness.

People with an irregular heartbeat (arrhythmia) and phenylketonuria (too much of the protein phenylalanine in the blood) should not take Emesafe 2Mg Oral Spray as it may cause serious conditions. The patient with liver disease should not take more than 8 mg of Emesafe 2Mg Oral Spray daily. Taking Emesafe 2Mg Oral Spray with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.

Emesafe 2Mg Oral Spray contains Ondansetron, an antiemetic drug, used in the prevention of vomiting and nausea.

Emesafe 2Mg Oral Spray is ineffective in preventing nausea associated with motion sickness.

Before taking Emesafe 2Mg Oral Spray, inform your doctor about all your medical conditions, sensitivities, and medications you are using. Also, tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Emesafe 2Mg Oral Spray usually works quickly, usually within 30 minutes, but it can take up to two hours for the full effect.

Common side effects of Emesafe 2Mg Oral Spray may include constipation, headache, diarrhea, drowsiness, flushing (a feeling of warmth), weakness, and tiredness. However, not every person experiences these side effects, and some of the unpleasant effects of Emesafe 2Mg Oral Spray do not require medical attention. If the side effects persist or worsen, please consult your doctor.

Emesafe 2Mg Oral Spray was not found to be beneficial in the treatment of seasickness.

Emesafe 2Mg Oral Spray works by blocking the action of a chemical in the body (serotonin) that is responsible for causing nausea and vomiting. As a result, Emesafe 2Mg Oral Spray prevents the sensation of nausea and vomiting caused by conditions like surgery, cancer chemotherapy, pregnancy, or motion sickness.

Yes, you can take Emesafe 2Mg Oral Spray half an hour to 1 hour before meals.

If you forget to take a dose of Emesafe 2Mg Oral Spray, take it as soon as you remember. However, if it is time for your next dose, skip the missed dose and take your regular dose. Never take a double dose to make up for a forgotten dose.

If you take more than the recommended dose of Emesafe 2Mg Oral Spray, it may result in an overdose. Signs and symptoms of an overdose of Emesafe 2Mg Oral Spray may include constipation, dizziness or lightheadedness, fainting, irregular heartbeat, and sudden loss of vision for a short time. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

No, Emesafe 2Mg Oral Spray is not a steroid. Emesafe 2Mg Oral Spray belongs to a class of drugs known as antiemetics.

While specific dosing instructions will vary depending on your individual needs and medical history. Always follow your doctor's prescribed dosage and timing for taking these medications.

Take Emesafe 2Mg Oral Spray exactly as prescribed by the doctor. Take it at the same time daily, as it will help you remember to take the medication.

Yes, Emesafe 2Mg Oral Spray can be given during pregnancy if prescribed by a doctor. However, it is not recommended for use during early pregnancy (first trimester), as it may increase the risk of birth defects in the mouth and face of the baby.

Country of origin

India

Manufacturer/Marketer address

Wallace Pharmaceuticals Pvt. Ltd., 3rd Floor, Dempo Trade Centre Bldg., Patto Plaza, EDC Complex, Panaji 403001, Goa, India.
Other Info - EME0097

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Sep 18, 2025 | 1:05 PM IST

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Reference

  1. https://pdf.hres.ca/dpd_pm/00068458.PDF
  2. https://assets.hpra.ie/products/Human/20212/1c456dc8-a1c3-4bbd-a64e-bf71394c3935.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020103s035_020605s019_020781s019lbl.pdf
  4. https://www.medicines.org.uk/emc/product/10160/smpc
  5. https://www.drugs.com/ondansetron.html
  6. https://medlineplus.gov/druginfo/meds/a601209.html

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