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EME OD 0.5 mg Tablet is used to prevent nausea and vomiting during chemotherapy. It contains Palonosetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre. In some cases, this medicine may cause side effects such as diarrhoea, constipation, dizziness or headache. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PALONOSETRON-0.5MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About EME OD 0.5 mg Tablet

EME OD 0.5 mg Tablet is a prescription medicine available in tablet and capsule forms to help prevent nausea and vomiting in adults undergoing cancer treatments. It is specifically designed to stop these symptoms before they start during chemotherapy sessions. This medication belongs to a group of supportive drugs that make cancer therapies more tolerable.

Unlike daily medications, you will typically take EME OD 0.5 mg Tablet as a single dose about one hour before your chemotherapy session begins. It can be taken with or without food, allowing for flexible use depending on how you feel. Making small changes, such as eating light meals before your treatment and staying well-hydrated, can further support your comfort.

While taking this medicine, some people may experience mild and temporary side effects like headaches or constipation. These effects are usually easy to manage, but you must contact your doctor immediately if you experience severe symptoms such as a rapid heartbeat, extreme muscle stiffness, or signs of an allergic reaction.

Before starting this medication, tell your doctor if you have a history of heart rhythm problems, liver damage, or unbalanced mineral levels in your blood. Do not take this if you have had an allergic reaction to similar nausea-preventing medicines in the past.

Certain antidepressants can interact with this medicine, potentially causing a serious chemical imbalance in your nervous system, so it is important to disclose all your current prescriptions. Additionally, avoid drinking alcohol as it can worsen dizziness and stomach irritation. If you are pregnant, breastfeeding, or an older adult, consult your doctor to discuss the risks and benefits before starting treatment.

Uses of EME OD 0.5 mg Tablet

EME OD 0.5 mg Tablet is used to help prevent and control nausea and vomiting caused by certain medical treatments, helping improve comfort and treatment adherence.

  • Chemotherapy-induced nausea and vomiting: EME OD 0.5 mg Tablet helps prevent nausea and vomiting caused by moderately to highly emetogenic chemotherapy regimens by blocking the chemical signals that trigger the vomiting reflex. 

Key Benefits

EME OD 0.5 mg Tablet offers the following benefits when used as prescribed during cancer treatment:

  • Prevents acute nausea and vomiting: EME OD 0.5 mg Tablet helps prevent nausea and vomiting caused by chemotherapy, allowing you to stay hydrated and maintain proper nutrition during your recovery.
  • Provides long-lasting protection against delayed nausea and vomiting: A single dose before chemotherapy helps protect against acute nausea and vomiting (within the first 24 hours) and delayed nausea and vomiting (24–120 hours after treatment), helping you remain comfortable throughout your recovery.
Side effects of EME OD 0.5 mg Tablet
Managing Medication-Triggered Anxiety: A Comprehensive Approach
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Directions for Use

  • EME OD 0.5 mg Tablet can be taken with or without food as recommended by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow EME OD 0.5 mg Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How EME OD 0.5 mg Tablet Works

EME OD 0.5 mg Tablet contains palonosetron, which is used to prevent nausea and vomiting during chemotherapy. Cancer treatments can trigger certain cells in your gut to release a natural chemical called serotonin. This chemical binds to specific sensors, known as 5-HT3 receptors, in your digestive tract and brain, sending a message that triggers the sensation of nausea and the reflex to vomit. EME OD 0.5 mg Tablet works as a serotonin blocker. By attaching itself to these 5-HT3 receptors, it prevents serotonin from sending the warning signals to your brain. This action keeps the vomiting reflex from being activated, helping prevent nausea before it begins.
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Alcohol

Consult your doctor

The interaction of alcohol with EME OD 0.5 mg Tablet is unknown. Please consult a doctor before consuming alcohol with EME OD 0.5 mg Tablet .

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Pregnancy

Consult your doctor

EME OD 0.5 mg Tablet is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant.

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Breast Feeding

Consult your doctor

Please consult a doctor before taking EME OD 0.5 mg Tablet if you are breastfeeding. EME OD 0.5 mg Tablet is given to breastfeeding women only if the doctor thinks benefits are greater than risks.

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Driving

Caution

EME OD 0.5 mg Tablet may cause tiredness or dizziness in some people. Therefore, avoid driving or operating heavy machinery if you feel tired or dizzy after taking EME OD 0.5 mg Tablet .

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Liver

Safe if prescribed

EME OD 0.5 mg Tablet may be safe to use in patients with liver problems if prescribed by a doctor.

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Kidney

Safe if prescribed

EME OD 0.5 mg Tablet may be safe to use in patients with kidney problems if prescribed by a doctor.

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Children

Unsafe

EME OD 0.5 mg Tablet is not recommended for children.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before taking EME OD 0.5 mg Tablet . Your doctor will prescribe it only if the potential benefits outweigh the possible risks.

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Geriatrics

Consult your doctor

EME OD 0.5 mg Tablet should be used in elderly patients only when prescribed by a doctor. If you have any concerns about using EME OD 0.5 mg Tablet for geriatrics, please consult a doctor.

What if I have taken an overdose of EME OD 0.5 mg Tablet

If you take more than the prescribed amount of EME OD 0.5 mg Tablet , seek immediate medical attention. Look out for symptoms such as severe dizziness, confusion, or a highly irregular heartbeat.

Diet & Lifestyle Advise

  • Eat smaller meals: Consume five or six small meals throughout the day instead of three large ones to keep your stomach from feeling too full.
  • Choose bland foods: Stick to dry toast, crackers, oatmeal, or plain rice, which are easier on the stomach than greasy, fried, or spicy foods.
  • Stay hydrated: Sip clear liquids like water, clear broths, or sports drinks slowly between meals rather than drinking large amounts during meals.
  • Rest upright: Avoid lying down flat for at least 30 to 60 minutes after eating to prevent acid reflux and ease digestion.
  • Avoid strong odors: Stay away from cooking smells, perfumes, or smoke, as strong scents can trigger sudden nausea.
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How Soon It Starts Working

The time required for EME OD 0.5 mg Tablet to start to work: EME OD 0.5 mg Tablet ideally shows its action within 60 minutes after administration. The time for which the effects of EME OD 0.5 mg Tablet last: The effect of EME OD 0.5 mg Tablet lasts for 72 hours.

What if you forget to take EME OD 0.5 mg Tablet

Because EME OD 0.5 mg Tablet is typically taken only once before chemotherapy, missing a dose means you may not be protected against nausea during your treatment. If you forget to take your dose at the scheduled time before your session, contact your doctor or healthcare team immediately for instructions.

Storage

• Store EME OD 0.5 mg Tablet tablets or capsules at room temperature, ideally between 20°C and 25°C (68°F to 77°F).•Keep the medication in its original packaging to protect it from light and moisture.

Drug Warnings

  • Check the packaging: Always check the packaging before taking the medicine to ensure it is sealed and has not expired.
  • Inform your healthcare provider: Tell your oncologist and pharmacist about all the medicines you take, including over-the-counter medicines, vitamins, and herbal supplements.
  • Avoid driving or operating machinery: Do not drive or operate machinery if you feel dizzy or unusually tired after taking EME OD 0.5 mg Tablet .
  • Watch for serotonin syndrome: Be alert for signs of serotonin syndrome, especially if you are also taking medicines for depression. Seek immediate medical attention if you develop symptoms such as agitation, confusion, fever, muscle stiffness, or a rapid heartbeat.
  • Use in children only if prescribed:EME OD 0.5 mg Tablet should only be used in children when prescribed by a healthcare professional. Always follow your doctor's instructions regarding the correct dose and duration of treatment.

Drug-Drug Interactions

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Some medicines may interact with EME OD 0.5 mg Tablet . Inform your doctor if you are taking any of the following:

  • Serotonergic medications: Taking EME OD 0.5 mg Tablet with certain antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs), may increase the risk of serotonin syndrome, a serious nervous system reaction.
  • Heart rhythm medications: Taking EME OD 0.5 mg Tablet with medicines that prolong the QT interval may increase the risk of an irregular heartbeat. Tell your doctor if you are taking medicines that affect heart rhythm.

Drug-Drug Interactions

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How does the drug interact with EME OD 0.5 mg Tablet:
Combining EME OD 0.5 mg Tablet with Ziprasidone can increase the risk of side effects.

How to manage the interaction:
Taking Ziprasidone with EME OD 0.5 mg Tablet is not recommended, please consult your doctor before taking it.
How does the drug interact with EME OD 0.5 mg Tablet:
Combining EME OD 0.5 mg Tablet with Amitriptyline can increase the risk of serotonin syndrome.(A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although using EME OD 0.5 mg Tablet and Amitriptyline together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medications without consulting a doctor.
How does the drug interact with EME OD 0.5 mg Tablet:
When linezolid is taken with EME OD 0.5 mg Tablet it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of linezolid along with EME OD 0.5 mg Tablet can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with EME OD 0.5 mg Tablet:
The combined use of EME OD 0.5 mg Tablet with clomipramine can increase the risk of serotonin syndrome (Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhea) to severe (muscle rigidity, fever, and seizures)).

How to manage the interaction:
Although taking clomipramine and EME OD 0.5 mg Tablet together can cause an interaction, it can be taken if your doctor has suggested it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor.
How does the drug interact with EME OD 0.5 mg Tablet:
When Vilazodone is taken with EME OD 0.5 mg Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Vilazodone and EME OD 0.5 mg Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with EME OD 0.5 mg Tablet:
The combined use of EME OD 0.5 mg Tablet and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of palponosetron and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with EME OD 0.5 mg Tablet:
Using chloroquine together with EME OD 0.5 mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking chloroquine and EME OD 0.5 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with EME OD 0.5 mg Tablet:
Coadministration of Amiodarone with EME OD 0.5 mg Tablet can lead to or increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Amiodarone with EME OD 0.5 mg Tablet together is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with EME OD 0.5 mg Tablet:
Using EME OD 0.5 mg Tablet together with paroxetine can increase the risk of condition called the serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Paroxetine with EME OD 0.5 mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, diarrhea, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with EME OD 0.5 mg Tablet:
Taking fentanyl with EME OD 0.5 mg Tablet may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking Fentanyl with EME OD 0.5 mg Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, muscle pain or stiffness, stomach cramps, vomiting, or diarrhoea, consult a doctor. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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Some foods and drinks may increase the risk of side effects while takingEME OD 0.5 mg Tablet .

  • Alcohol: Drinking alcohol while takingEME OD 0.5 mg Tablet may increase dizziness, headaches, and stomach irritation. It is best to avoid or limit alcohol during treatment, especially while receiving chemotherapy.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIEMETICS]

FAQs

EME OD 0.5 mg Tablet contains Palonosetron that works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.
You are not recommended to take erythromycin with EME OD 0.5 mg Tablet as it may increase the risk of severe irregular heart rhythm. However, please consult your doctor before taking other medicines with EME OD 0.5 mg Tablet .
EME OD 0.5 mg Tablet may cause constipation as a side effect. It is not necessary for everyone taking EME OD 0.5 mg Tablet to experience this side effect. However, if the condition persists or worsens, please consult a doctor.
EME OD 0.5 mg Tablet should be used with caution in patients suffering from heart problems as it may worsen the condition. Therefore, inform your doctor if you have any heart problems before taking have EME OD 0.5 mg Tablet so that the dose may be adjusted appropriately.
You are not recommended to stop taking EME OD 0.5 mg Tablet without consulting your doctor as it may increase the risk of nausea and vomiting during chemotherapy. Therefore, take EME OD 0.5 mg Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking EME OD 0.5 mg Tablet , please consult your doctor.
Yes, you can take EME OD 0.5 mg Tablet with or without food. Taking it with a light meal or snack may help if you have a sensitive stomach, but it does not affect how well the medicine works. Talk to your doctor if you have questions about your diet during treatment.
You should typically take EME OD 0.5 mg Tablet about one hour before your chemotherapy treatment begins. This timing allows the medicine to absorb fully into your body and start blocking nausea signals before the therapy starts. Talk to your doctor to confirm your specific timing.
EME OD 0.5 mg Tablet is primarily designed to prevent nausea and vomiting from occurring, rather than treating active, ongoing symptoms. It is most effective when taken before your cancer treatment starts. If you experience breakthrough nausea during or after your therapy, talk to your doctor.
Drowsiness is not a highly common side effect of EME OD 0.5 mg Tablet , but some people do report feeling tired or weak after taking it. If you experience fatigue or dizziness, avoid driving or operating heavy machinery until you know how the medicine affects you. Talk to your doctor if this tiredness persists.
It is generally best to avoid alcohol while taking EME OD 0.5 mg Tablet and undergoing chemotherapy. Alcohol can worsen side effects like dizziness, headaches, and dehydration, and it may irritate your stomach lining. Talk to your doctor about whether any amount of alcohol is safe for you.
If you throw up shortly after taking your dose, do not take an extra tablet or capsule on your own. Contact your healthcare team or clinic immediately to let them know, as they will advise you on the safe next steps before your chemotherapy session. Talk to your doctor for specific advice.
The safety of EME OD 0.5 mg Tablet during pregnancy and breastfeeding has not been fully established. Your doctor will weigh the potential benefits of preventing nausea against any risks to the baby before prescribing this medicine. Talk to your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Some antidepressants can interact with EME OD 0.5 mg Tablet , increasing the risk of a rare but serious condition called serotonin syndrome. It is vital to provide your healthcare team with a complete list of all medications you currently take. Talk to your doctor to ensure this combination is safe for you.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - EME0052
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