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  3. Dysport 500 Injection 1's

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Dysport 500 Injection 1's, Pack of 1
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Dysport 500 Injection is used for muscle relaxation and the symptomatic treatment of upper limb spasticity in paediatric cerebral palsy patients aged two years or older. It contains Clostridium botulinum type A toxin haemagglutinin complex, which acts on the junctions between the nerves and muscles, preventing the release of acetylcholine (a chemical messenger) from the nerve endings that would generally cause the muscle to contract. Thereby, it helps reduce abnormal muscle contractions.

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Composition :

CLOSTRIDIUM BOTULINUM TYPE A TOXIN HAEMAGGLUTININ COMPLEX-500IU

Manufacturer/Marketer :

Bharat Serums and Vaccines Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Dysport 500 Injection

Dysport 500 Injection belongs to a group of medicines called muscle relaxants used to treat upper limb spasticity, lower limb spasticity, spasmodic torticollis (neck muscle contraction), blepharospasm (abnormal contraction of the eyelid muscles), hemifacial spasm (contractions or spasms of the muscles on one side of the face), moderate to severe glabellar lines (worry lines), and moderate to severe lateral canthal line (crow's feet or laugh lines).

Dysport 500 Injection contains Clostridium botulinum type A toxin haemagglutinin complex, which acts on the junctions between the nerves and muscles, preventing the release of acetylcholine (a chemical messenger) from the nerve endings that would normally cause the muscle to contract. Thereby, it helps reduce abnormal muscle contractions.

In some cases, Dysport 500 Injection may cause injection site reactions, headache, tiredness, generalised weakness, and flu-like symptoms. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in Dysport 500 Injection. Dysport 500 Injection should not be used during pregnancy or lactation. Dysport 500 Injection may cause muscle weakness or visual disturbances; therefore, drive only if you are alert. Inform the doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Dysport 500 Injection

Dysport 500 Injection is used for Muscle relaxation and the symptomatic treatment of upper limb spasticity in paediatric cerebral palsy patients aged two years or older. The detailed uses of Dysport 500 Injection are as follows:<br/>• Focal Muscle Spasms and Dystonia: Dysport 500 Injection is used to treat localized muscle spasms, cervical dystonia (neck muscle contractions), and conditions like blepharospasm (eyelid twitching) and spasmodic torticollis. It works by blocking nerve signals that cause excessive muscle contractions.<br/>• Spasticity in Adults and Children: Dysport 500 Injection is used for managing upper and lower limb spasticity in adults following stroke or traumatic brain injury, and in children with cerebral palsy. It helps relax overactive muscles and improve mobility and comfort.<br/>• Cosmetic and Neurological Applications: Dysport 500 Injection is also used to reduce facial wrinkles (like glabellar lines), manage squint (strabismus), and treat chronic migraines by relaxing targeted muscles and reducing nerve activity.<br/>

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Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Dysport 500 Injection will be administered by a healthcare professional.• Do not self-administer it.

Medicinal Benefits

Dysport 500 Injection belongs to a group of medicines called muscle relaxants used to treat upper limb spasticity, lower limb spasticity, spasmodic torticollis (neck muscle contraction), blepharospasm (abnormal contraction of the eyelid muscles), hemifacial spasm (contractions or spasms of the muscles on one side of the face), moderate to severe glabellar lines (worry lines), and moderate to severe lateral canthal line (crow's feet or laugh lines). Dysport 500 Injection contains Clostridium botulinum type A toxin haemagglutinin complex, which acts on the junctions between the nerves and muscles, preventing the release of acetylcholine (a chemical messenger) from the nerve endings that would normally cause the muscle to contract. Thereby, it helps reduce abnormal muscle contractions.

How Dysport 500 Injection Works

Dysport 500 Injection contains Clostridium botulinum type A toxin haemagglutinin complex, which acts on the junctions between the nerves and muscles, preventing the release of acetylcholine (a chemical messenger) from the nerve endings that would normally cause the muscle to contract. Thereby, it helps reduce abnormal muscle contractions.

Storage

• Store in a cool and dry place away from sunlight.• Keep Dysport 500 Injection out of reach and sight of children.• Cold chain - To be stored in cold places at 2ºC to 8ºC.
Side effects of Dysport 500 Injection
  • Painful urination can be reduced by drinking lots of water.
  • Don't hold urine, as it can worsen the pain during urination.
  • Try taking probiotics and eating garlic, which can help reduce painful urination.
  • Sleep well and give enough rest to your body.
  • Take a balanced diet and avoid bladder-irritating foods.
  • Quit smoking and intake of alcohol.
  • Practice yoga and meditation to improve inner strength and stay healthy.
  • Do pelvic floor exercises (Kegel exercises) to gain more control over urinary sphincters (muscles used to control flow of urine out of the bladder).
  • Drink fluids only at certain times to control when you will urinate.
  • If you feel frequent urge to urinate or have problems starting to urinate or if your urine stream is weak or starts and stops, or feel pain in your genitals, lower abdomen or lower back, consult your doctor.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.

What if I have taken an overdose of Dysport 500 Injection

As Dysport 500 Injection is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not use Dysport 500 Injection if you are allergic to any of its components, if you have an infection at the proposed site of injection, myasthenia gravis (muscle problems), Eaton-Lambert Syndrome (neuromuscular junction disorder affecting communication between nerves and muscles), or amyotrophic lateral sclerosis (nervous system disease that weakens muscles). Inform the doctor if you have any neuromuscular disorders, dysphagia (difficulty swallowing food), weak muscles at the proposed site of injection, problems with food or drink getting into your airways, causing you to cough or choke, or bleeding disorders. Dysport 500 Injection should not be used during pregnancy or lactation. Dysport 500 Injection may cause muscle weakness or visual disturbances; therefore, drive only if you are alert. Let the doctor know if you have had surgery on your face or are likely to undergo facial or other types of surgery soon.

Drug-Drug Interactions

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Botulinum toxinSpectinomycin
Severe
Botulinum toxinVecuronium
Severe

Drug-Drug Interactions

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Botulinum toxinSpectinomycin
Severe
How does the drug interact with Dysport 500 Injection:
Coadministration of Dysport 500 Injection with Spectinomycin may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Dysport 500 Injection and Spectinomycin, it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
Botulinum toxinVecuronium
Severe
How does the drug interact with Dysport 500 Injection:
Using Dysport 500 Injection and vecuronium together may increase the risk of certain side effects.

How to manage the interaction:
Although there is an interaction between Dysport 500 Injection and Vecuronium, it can be taken if your doctor has advised it. Contact your doctor immediately if you experience any side effects like muscle weakness, trouble breathing, or swallowing. Do not discontinue any medications without consulting a doctor.
Botulinum toxinGentamicin
Severe
How does the drug interact with Dysport 500 Injection:
Using Gentamicin with Dysport 500 Injection can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Dysport 500 Injection and Gentamicin, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
Botulinum toxinAtracurium
Severe
How does the drug interact with Dysport 500 Injection:
Coadministration of Dysport 500 Injection with Atracurium may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Dysport 500 Injection and Atracurium, it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience excessive muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
Botulinum toxinNetilmicin
Severe
How does the drug interact with Dysport 500 Injection:
Coadministration of Dysport 500 Injection with Netilmicin may increase the risk of certain side effects due to additive effects.

How to manage the interaction:
Although there is an interaction between Dysport 500 Injection and netilmicin, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
Botulinum toxinPancuronium
Severe
How does the drug interact with Dysport 500 Injection:
Coadministration of Pancuronium with Dysport 500 Injection can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Dysport 500 Injection and pancuronium, it can be taken if prescribed by a doctor. However, if you experience muscle weakness or trouble breathing, swallowing, or speaking, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Botulinum toxinAmikacin
Severe
How does the drug interact with Dysport 500 Injection:
Coadministration of Dysport 500 Injection with Amikacin may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Dysport 500 Injection and amikacin, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience muscle weakness or difficulty breathing, swallowing, and speaking. Do not discontinue any medications without consulting a doctor.
Botulinum toxinTobramycin
Severe
How does the drug interact with Dysport 500 Injection:
Using Dysport 500 Injection and tobramycin together may increase the risk of side effects.

How to manage the interaction:
Although taking Dysport 500 Injection and Tobramycin can cause an interaction, it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience excessive muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
Botulinum toxinDoxacurium chloride
Severe
How does the drug interact with Dysport 500 Injection:
Using Dysport 500 Injection with Doxacurium chloride may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Dysport 500 Injection and Doxacurium chloride, it can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
Botulinum toxinTubocurarine
Severe
How does the drug interact with Dysport 500 Injection:
Using Dysport 500 Injection with Tubocurarine may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Dysport 500 Injection and tubocurarine, it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try to be healthy by eating proper food and exercising regularly.
  • Avoid smoking and alcohol consumption.
  • Stay hydrated.
  • Rest properly; get optimum sleep.

Habit Forming

No

Therapeutic Class

MUSCLE RELAXANTS
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Alcohol

Consult your doctor

It is not known if alcohol affects Dysport 500 Injection. Please consult a doctor.

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Pregnancy

Unsafe

Dysport 500 Injection is not recommended for use during pregnancy. Consult the doctor if you are pregnant, planning for pregnancy or think you may be pregnant.

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Breast Feeding

Unsafe

Dysport 500 Injection is not recommended for use during lactation. Please consult the doctor if you are breastfeeding.

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Driving

Caution

Dysport 500 Injection may cause visual disturbances or muscle weakness. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Please consult the doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Please consult the doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Dysport 500 Injection can be used for the treatment of upper and lower limb spasticity in children above two years. It should not be used for other conditions in children.

FAQs

Dysport 500 Injection is used for Muscle relaxation and the symptomatic treatment of upper limb spasticity in paediatric cerebral palsy patients aged two years or older.

Dysport 500 Injection prevents the release of acetylcholine, a chemical messenger that causes the muscle to contract. Thereby, it helps reduce abnormal muscle contractions.

Dysport 500 Injection may cause injection site reactions like pain, burning, tingling, redness, bruising, rash, itching, stinging, irritation, or discomfort. If the conditions persist or worsen, consult the doctor.

Dose adjustment may be needed in the elderly where reduced muscle mass may exist. Talk to the doctor if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

17Th Floor, Hoechst House, Nariman Point, Mumbai 400 021, Maharashtra, India.
Other Info - DYS0025

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:19 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.13798.pdf
  2. https://www.nps.org.au/assets/medicines/414a6855-e4a0-4610-8d13-a53300ff15bb-reduced.pdf

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