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  3. Dyronib 50 Tablet 60's

Dyronib 50 Tablet 60's, Pack of 1 TABLET
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Dyronib 50 Tablet is used to treat Philadelphia chromosome-positive chronic myeloid leukaemia and acute lymphoblastic leukaemia. It contains Dasatinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce their further spread to other parts of the body.

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Composition :

DASATINIB-50MG

Manufacturer/Marketer :

Hetero Drugs Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dyronib 50 Tablet

Dyronib 50 Tablet is an anti-cancer medicine used in the treatment of Leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. There are different types of blood cancers. Dyronib 50 Tablet is used in the treatment of chronic myelogenous leukemia (CML) in patients with chronic, accelerated, or blast phase Ph+ (Philadelphia chromosome-positive) who are resistant or intolerant to prior therapy, in patients with newly diagnosed chronic Ph+ chronic myelogenous leukemia (CML). This medicine is also used in the treatment of Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL).

Dyronib 50 Tablet contains Dasatinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body.

Dyronib 50 Tablet may cause certain side effects, such as skin rash, fatigue, headache, musculoskeletal pain, decreased platelet count, nausea, vomiting, diarrhea, abdominal pain, dizziness, GI bleeding, muscle inflammation, myalgia, and difficulty breathing. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Dyronib 50 Tablet should be taken as advised by your doctor. Do not take more than the recommended dose of medicine. Your doctor will decide the dose of Dyronib 50 Tablet based on the severity of your condition.

Dyronib 50 Tablet should be avoided if you are allergic to it or any other components present in it. Before taking Dyronib 50 Tablet , caution should be exercised if you have/had liver/kidney disease, gastrointestinal disorders, cardiac problems, and myelosuppression as may cause serious side effects or worsen such conditions. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment with Dyronib 50 Tablet . Breastfeeding should be discontinued in nursing mothers during the treatment.

Uses of Dyronib 50 Tablet

Dyronib 50 Tablet is used in the treatment of Philadelphia chromosome-positive chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia. The detailed uses of Dyronib 50 Tablet are as follows:<br/>• Chronic Myeloid Leukemia (CML): Dyronib 50 Tablet is used to treat chronic myeloid leukemia especially philadelphia chromosome-positive (Ph+) CML, in both newly diagnosed and resistant/intolerant cases.<br/>• Acute Lymphoblastic Leukemia (ALL): Dyronib 50 Tablet is used to treat acute lymphoblastic leukemia and also Ph+ ALL, who are newly diagnosed or have relapsed.<br/>

Directions for Use

• Dyronib 50 Tablet can be taken with or without food, as food does not affect its absorption or effectiveness.• It is usually taken once a day, or as prescribed by your doctor.• Swallow Dyronib 50 Tablet as a whole with water.• Do not crush, chew or break Dyronib 50 Tablet .

Medicinal Benefits

Dyronib 50 Tablet contains Dasatinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins (BCR-ABL tyrosine kinase) that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. Dyronib 50 Tablet is used in the treatment of Philadelphia chromosome-positive chronic myeloid leukemia and acute lymphoblastic leukemia.

How Dyronib 50 Tablet Works

Dyronib 50 Tablet contains Dasatinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Dyronib 50 Tablet out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Dyronib 50 Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Dyronib 50 Tablet are unusual bruising or bleeding, fever, sore throat, chills, and/or other signs of infection, shortness of breath, fast heartbeat, headache, pale skin, confusion and tiredness. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Dyronib 50 Tablet should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before taking, inform your doctor if you have liver/kidney disease, diabetes, cardiac problems, increased blood pressure, or gastrointestinal disorders, as the use of Dyronib 50 Tablet in these patients may cause serious side effects. Dyronib 50 Tablet may cause myelosuppression, fluid retention, gastrointestinal haemorrhage, QT prolongation, congestive heart failure, Left ventricular dysfunction and Myocardial infarction. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment. Breastfeeding should be discontinued in nursing mothers during the treatment. Dyronib 50 Tablet is given in children above one year of age only if prescribed by the doctor. Avoid alcohol consumption and smoking, as it can lead to serious adverse effects.

Drug-Drug Interactions

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DasatinibMesoridazine
Critical
DasatinibPimozide
Critical

Drug-Drug Interactions

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DasatinibMesoridazine
Critical
How does the drug interact with Dyronib 50 Tablet:
Using Mesoridazine together with Dyronib 50 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Dyronib 50 Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without talking to a doctor.
DasatinibPimozide
Critical
How does the drug interact with Dyronib 50 Tablet:
Using Pimozide together with Dyronib 50 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Dyronib 50 Tablet with Pimozide is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without talking to a doctor.
DasatinibHalofantrine
Critical
How does the drug interact with Dyronib 50 Tablet:
Using Halofantrine together with Dyronib 50 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Dyronib 50 Tablet with Halofantrine is not recommended, consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without doctor's advice.
DasatinibDronedarone
Critical
How does the drug interact with Dyronib 50 Tablet:
Using dronedarone together with Dyronib 50 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Dyronib 50 Tablet with Dronedarone is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medication without doctor's advice.
DasatinibFosamprenavir
Severe
How does the drug interact with Dyronib 50 Tablet:
Coadministration of Dyronib 50 Tablet with Fosamprenavir may significantly increase the blood levels of Dyronib 50 Tablet.

How to manage the interaction:
Although taking Dyronib 50 Tablet and Fosamprenavir together can cause an interaction, it can be taken if a doctor has suggested it. If you experience symptoms like dizziness, shortness of breath, reach out to a doctor right away. Do not stop using any medications without a doctor's advice.
DasatinibDipyridamole
Severe
How does the drug interact with Dyronib 50 Tablet:
Coadministration of Dyronib 50 Tablet with Dipyridamole can increase the risk of bleeding tendencies.

How to manage the interaction:
Co-administration of Dyronib 50 Tablet with Dipyridamole can result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like bruising, feeling dizzy or lightheaded, having dark stools, headaches, weakness, - make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
DasatinibRitonavir
Severe
How does the drug interact with Dyronib 50 Tablet:
When Ritonavir is taken with Dyronib 50 Tablet may significantly increase the blood levels of Dyronib 50 Tablet.

How to manage the interaction:
Taking Dyronib 50 Tablet with Ritonavir together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience pain or burning when urinating, muscle aches, dizziness, shortness of breath, heart palpitations contact a doctor. Do not stop using any medications without talking to a doctor.
DasatinibDexamethasone
Severe
How does the drug interact with Dyronib 50 Tablet:
Taking Dexamethasone may reduce the blood levels of Dyronib 50 Tablet, making the medication less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction, Dexamethasone can be taken with Dyronib 50 Tablet if prescribed by the doctor. In case of any unusual side effects, consult a doctor. Do not discontinue the medication without consulting a doctor.
DasatinibTenecteplase
Severe
How does the drug interact with Dyronib 50 Tablet:
Taking Dyronib 50 Tablet with Tenecteplase can increase the risk and severity of bleeding and hemorrhage.

How to manage the interaction:
Although taking Tenecteplase and Dyronib 50 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. You should seek immediate medical attention if you experience dizziness; red or black, tarry stools; severe headache; and weakness. Do not discontinue any medications without consulting a doctor.
DasatinibHaloperidol
Severe
How does the drug interact with Dyronib 50 Tablet:
Co-administration of Dyronib 50 Tablet with Haloperidol can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Dyronib 50 Tablet with Haloperidol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms like dizziness, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • After beginning your treatment, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Dyronib 50 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Dyronib 50 Tablet to prevent serious adverse effects.

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Pregnancy

Unsafe

When given to a pregnant woman, Dyronib 50 Tablet may cause fetal harm. There have been no sufficient and well-controlled investigations of Dyronib 50 Tablet in pregnant women. Women of reproductive potential should avoid becoming pregnant while undergoing treatment with this medicine.

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Breast Feeding

Unsafe

It is not known if Dyronib 50 Tablet passes into your breast milk. Inform your doctor if you are breastfeeding. You should not breastfeed while taking this medicine and for 2 weeks of the treatment with Dyronib 50 Tablet . Your doctor may prescribe an alternative based on the symptoms and health condition.

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Driving

Unsafe

Dyronib 50 Tablet may cause dizziness and may make you feel drowsy. Hence, avoid driving or operating machines after taking Dyronib 50 Tablet or until you become alert.

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Liver

Caution

Use Dyronib 50 Tablet with caution if you have liver disease. Your doctor may monitor your liver function while taking this medicine. No dose adjustments are necessary in patients with liver impairment.

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Kidney

Caution

There are presently no clinical investigations with Dyronib 50 Tablet in patients with compromised renal function. If you have kidney problems, inform your doctor before taking this medicine.

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Children

Consult your doctor

Dyronib 50 Tablet is safe for use in children above one year of age if prescribed by the doctor.

Have a query?

FAQs

Dyronib 50 Tablet is used to treat Philadelphia chromosome-positive chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia.

Dyronib 50 Tablet contains Dasatinib, which works by inhibiting the action of abnormal proteins that cause the multiplication of cancerous cells.

Dyronib 50 Tablet is known to cause embryo-fetal toxicity; hence, it is contraindicated for use in pregnancy. A woman needs to have a negative pregnancy test before starting treatment with this medicine. It is better to use effective birth control methods to prevent pregnancy while taking this medicine or at least six months after completion of the treatment.

Take antacids such as aluminium hydroxide/magnesium hydroxide, calcium carbonate, calcium carbonate, and magnesium 2 hours before or after taking Dyronib 50 Tablet as antacids may alter the absorption of this medicine.

Country of origin

India

Manufacturer/Marketer address

2Nd Floor, 8-3-166/7/1 Erragadda, Hyderabad-500018
Other Info - DYR0018

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:22 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021986s7s8lbl.pdf
  2. https://medlineplus.gov/druginfo/meds/a607063.html
  3. https://go.drugbank.com/drugs/DB01254
  4. https://www.sprycel.com/

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