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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Dyril Plus 100 mg/300 mg Tablet is used to treat bacterial infections, dysentery and diarrhoea. It contains furazolidone and metronidazole, which kill the parasites and bacteria that cause infections. In some cases, this medicine may cause side effects such as nausea, dry mouth, headache, metallic taste, and discolouration of urine. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Manufacturer/Marketer :

Rhombus Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Dyril Plus 100 mg/300 mg Tablet

Dyril Plus 100 mg/300 mg Tablet belongs to a class of medicines known as antibiotics used to treat various infections caused by bacteria, dysentery and diarrhoea. A bacterial infection is a condition in which harmful bacteria enter, multiply and infect our bodies. It can target any body part and multiply very quickly. Amoebic dysentery can be caused by Entamoeba histolytica, Giardia lamblia or Clostridium difficile. Diarrhoea is an increase in bowel movement leading to increased and loose motions.

Dyril Plus 100 mg/300 mg Tablet contains furazolidone and metronidazole. Flurazolidone works by interfering with protein synthesis, a mechanism which is important for the survival of bacteria. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA. Collectively, they help in treating the disease effectively.

Take Dyril Plus 100 mg/300 mg Tablet as prescribed by your doctor. Your doctor will recommend how often you take Dyril Plus 100 mg/300 mg Tablet based on your medical condition. Some people may experience nausea, dryness in the mouth, headache, metallic taste, and dark yellow to brown discolouration of urine. Most of these side effects of Dyril Plus 100 mg/300 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take Dyril Plus 100 mg/300 mg Tablet if you are allergic to any of its components. It is not advisable to stop taking Dyril Plus 100 mg/300 mg Tablet suddenly; the full course prescribed by the doctor should be completed. Dyril Plus 100 mg/300 mg Tablet may cause blurred vision or dizziness that may affect the ability to drive or use machines; drive only if you are alert. Dyril Plus 100 mg/300 mg Tablet should be given to children if advised by the doctor.

Uses of Dyril Plus 100 mg/300 mg Tablet

Dyril Plus 100 mg/300 mg Tablet is used in the treatment of Bacterial infection, Diarrhoea, Dysentery, and Intestinal infection. The detailed uses of Dyril Plus 100 mg/300 mg Tablet are as follows:<br/> • Treatment of diarrhoea and dysentery: Dyril Plus 100 mg/300 mg Tablet targets bacterial infections in the digestive tract and treats diarrhoea.<br/> • Prevention of intestinal infections: Dyril Plus 100 mg/300 mg Tablet inhibits bacterial growth to curb further complications.<br/> • Relief from stomach issues: Dyril Plus 100 mg/300 mg Tablet addresses discomfort linked to gastrointestinal conditions.<br/> • Antimicrobial action: Dyril Plus 100 mg/300 mg Tablet eliminates specific bacteria and protozoa causing infections.<br/>

Directions for Use

  • Take Dyril Plus 100 mg/300 mg Tablet with food to avoid stomach upset or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Dyril Plus 100 mg/300 mg Tablet is a combination of two medicines namely furazolidone and metronidazole. It is used to treat various infections caused by bacteria, dysentery, and diarrhoea. It is also used to treat intestinal infections, typhoid fever and skin infections. Furazolidone works by interfering with protein synthesis, a mechanism which is important for the survival of bacteria. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA. Collectively, they help in treating the disease effectively.

How Dyril Plus 100 mg/300 mg Tablet Works

Dyril Plus 100 mg/300 mg Tablet is a combination of two antibiotics that include furazolidone and metronidazole. Flurazolidone works by interfering with protein synthesis, a mechanism which is important for the survival of bacteria. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA. Collectively, they help in treating the disease effectively.

Storage

• Store in a cool and dry place away from sunlight.• Keep this medicine out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Dyril Plus 100 mg/300 mg Tablet

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

If you are allergic to furazolidone, metronidazole or any other antibacterial or anti-amoebic agents, please inform your doctor to avoid any unwanted side effects. Dyril Plus 100 mg/300 mg Tablet should not be taken in conditions like liver disease or kidney disease. Before taking Dyril Plus 100 mg/300 mg Tablet, inform your doctor if you have a fit disorder, numbness, or pain in your feet or hands. Dyril Plus 100 mg/300 mg Tablet may have a low white blood cell count (leukopenia). Dyril Plus 100 mg/300 mg Tablet may cause convulsions (rapid contraction and relaxation of body muscles). If you observe these symptoms, immediately contact your doctor. Discontinue the Dyril Plus 100 mg/300 mg Tablet if any signs of low blood count are observed. Immediately inform your doctor if you experience swelling of the face, tongue, throat, itchy rash, or breathing difficulties while taking this Dyril Plus 100 mg/300 mg Tablet. Dyril Plus 100 mg/300 mg Tablet is safely given to children above one month of age. It is advisable that you do not drive while using Dyril Plus 100 mg/300 mg Tablet as Dyril Plus 100 mg/300 mg Tablet may cause blurred vision or dizziness that may affect the ability to drive or use machines. It is not advisable to stop taking Dyril Plus 100 mg/300 mg Tablet suddenly to avoid unpleasant side effects. The full course prescribed by the doctor should be completed.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Dyril Plus 100 mg/300 mg Tablet:
When Clomipramine is taken with Dyril Plus 100 mg/300 mg Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Clomipramine and Dyril Plus 100 mg/300 mg Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dyril Plus 100 mg/300 mg Tablet:
Combining Dyril Plus 100 mg/300 mg Tablet with Amitriptyline can increase the risk of serotonin syndrome(increased serotonin hormone).

How to manage the interaction:
Although using Dyril Plus 100 mg/300 mg Tablet and Amitriptyline together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dyril Plus 100 mg/300 mg Tablet:
Taking Dyril Plus 100 mg/300 mg Tablet with Fluvoxamine can increase the risk of serotonin syndrome(A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Fluvoxamine with Dyril Plus 100 mg/300 mg Tablet is not recommended, but can be taken if prescribed by a doctor. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dyril Plus 100 mg/300 mg Tablet:
Combining Dyril Plus 100 mg/300 mg Tablet and Tetrabenazine can increase the risk of high blood pressure.

How to manage the interaction:
Taking Dyril Plus 100 mg/300 mg Tablet and Tetrabenazine together is not recommended as it can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness, speech difficulties, fever, sweating, lightheadedness, and fainting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Dyril Plus 100 mg/300 mg Tablet:
When Vilazodone is taken with Dyril Plus 100 mg/300 mg Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Vilazodone with Dyril Plus 100 mg/300 mg Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dyril Plus 100 mg/300 mg Tablet:
Using Dyril Plus 100 mg/300 mg Tablet together with phenylephrine can cause severe high blood pressure.

How to manage the interaction:
Taking Pheniramine with Dyril Plus 100 mg/300 mg Tablet is not recommended, but can be taken together if prescribed by a doctor. However, if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dyril Plus 100 mg/300 mg Tablet:
Combining Dyril Plus 100 mg/300 mg Tablet with Oxcarbazepine can increase the risk of serotonin syndrome(a condition when your body has too much of a chemical called serotonin), further leading to side effects.

How to manage the interaction:
Taking Oxcarbazepine with Dyril Plus 100 mg/300 mg Tablet is not recommended, as it can result in an interaction, but it can be taken if prescribed by a doctor. However, if you experience symptoms such as confusion, hallucination (seeing or hearing things that do not exist), seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhoea, consult a doctor. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Dyril Plus 100 mg/300 mg Tablet:
Using Dyril Plus 100 mg/300 mg Tablet together with atomoxetine can cause serious high blood pressure.

How to manage the interaction:
Taking Atomoxetine with Dyril Plus 100 mg/300 mg Tablet is not recommended, consult a doctor before taking it. You should seek immediate medical attention if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dyril Plus 100 mg/300 mg Tablet:
Taking Dyril Plus 100 mg/300 mg Tablet with Phenylephrine can cause an increase in high blood pressure.

How to manage the interaction:
Taking Dyril Plus 100 mg/300 mg Tablet with Phenylephrine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Phenylephrine only after 14 days of stopping Dyril Plus 100 mg/300 mg Tablet.
How does the drug interact with Dyril Plus 100 mg/300 mg Tablet:
Taking Dyril Plus 100 mg/300 mg Tablet with Paroxetine can increase the risk of side effects

How to manage the interaction:
Taking Paroxetine with Dyril Plus 100 mg/300 mg Tablet is not recommended, but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, or blurred vision contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do not drink or eat a lot of caffeine-containing products such as coffee, tea, energy drinks, cola or chocolate. Dyril Plus 100 mg/300 mg Tablet may increase nervousness, sleeplessness and anxiety caused by caffeine.
  • Probiotics should be taken after taking the full course of Dyril Plus 100 mg/300 mg Tablet in order to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet. Make sure you drink plenty of water or other fluids every day while you are taking Dyril Plus 100 mg/300 mg Tablet.
  • Avoid intake of alcoholic beverages with Dyril Plus 100 mg/300 mg Tablet as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Dyril Plus 100 mg/300 mg Tablet in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS
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Alcohol

Unsafe

Drinking alcohol while taking this Dyril Plus 100 mg/300 mg Tablet may lead to an unpleasant reaction with symptoms like stomach pain, vomiting, nausea, flushing, headache or redness of the face.

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Pregnancy

Unsafe

Dyril Plus 100 mg/300 mg Tablet should not be taken if you are pregnant or planning to have a baby. If you become pregnant while taking Dyril Plus 100 mg/300 mg Tablet, stop taking the medication, and contact your doctor immediately. Metronidazole should not be given in the first trimester of the pregnancy as it may cause harm to the fetus.

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Breast Feeding

Caution

Take Dyril Plus 100 mg/300 mg Tablet only when prescribed, Dyril Plus 100 mg/300 mg Tablet contains ‘metronidazole’ which is known to pass on in a limited quantity via breast milk to the child. Consult your doctor for further advice.

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Driving

Caution

Do not drive while using Dyril Plus 100 mg/300 mg Tablet as Dyril Plus 100 mg/300 mg Tablet may cause blurred vision or dizziness that may affect the ability to drive or using machines.

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Liver

Caution

Dyril Plus 100 mg/300 mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Dyril Plus 100 mg/300 mg Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Dyril Plus 100 mg/300 mg Tablet can be given to the children for typhoid fever, diarrhea, a stomach infection, amoebiasis, abdominal infection, diarrhea and intestinal infection only when prescribed by a child specialist.

Have a query?

FAQs

Dyril Plus 100 mg/300 mg Tablet is used to treat bacterial infections, dysentery and diarrhoea.

Dyril Plus 100 mg/300 mg Tablet contains furazolidone and metronidazole. Flurazolidone works by interfering with protein synthesis, a mechanism which is important for the survival of bacteria. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA. Collectively, they help in treating the disease effectively.

Yes, Dyril Plus 100 mg/300 mg Tablet is known to cause dry mouth. If you feel excessively thirsty, do frequent mouth rinses and increase fluid intake.

Yes, Dyril Plus 100 mg/300 mg Tablet may lead to a temporary metallic taste. This metallic taste can be reduced by chewing mints, sugar-free gum and brushing teeth after the food.

No, do not stop taking Dyril Plus 100 mg/300 mg Tablet and complete the full course of treatment even if you feel well. Your symptoms may recur before the infection is completely treated.

Yes, Dyril Plus 100 mg/300 mg Tablet may cause nausea and vomiting in some patients. You are recommended to take Dyril Plus 100 mg/300 mg Tablet with meals to avoid this. If you still vomit or feel nauseous, please consult your doctor.

No, you are recommended not to take Dyril Plus 100 mg/300 mg Tablet with other antibiotics. Dyril Plus 100 mg/300 mg Tablet is an antibiotic medicine that is used to treat parasitic and amoebic infections. When taken along with other antibiotics, Dyril Plus 100 mg/300 mg Tablet may lose its efficiency, or it might result in unwanted side effects.

Drinking alcohol while taking Dyril Plus 100 mg/300 mg Tablet may lead to an unpleasant reaction with symptoms like stomach pain, vomiting, nausea, flushing, and headache. So, it is important to avoid alcohol consumption during the treatment with Dyril Plus 100 mg/300 mg Tablet.

Store Dyril Plus 100 mg/300 mg Tablet in a cool and dry place away from sunlight. Keep it out of the reach of children. Regularly check the expiration date. When you need to dispose of the medicine, place it in a plastic bag and throw it away in the household trash. Remember, never flush the medicine down the toilet or sink.

The common side effects of Dyril Plus 100 mg/300 mg Tablet which may occur in some individuals are nausea, dryness in the mouth, headache, metallic taste, and dark yellow to brown discoloration of urine. Most of these side effects do not require medical attention and gradually resolve over time. However, if these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

816/1, Pramukh Industrial Estate, Rakanpur, Santej, Gujarat 382721
Other Info - DY69915

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