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  3. DYRADE M TABLET

DYRADE M TABLET, Pack of 10 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

DYRADE M TABLET is used to treat infections caused by bacteria and parasites (amoeba). It contains Metronidazole and Diloxanide, which work by killing the infection-causing bacteria and amoeba. This medicine may occasionally cause side effects, such as nausea, vomiting, upset stomach, loss of appetite, dry mouth, and a metallic taste. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

DILOXANIDE-250MG + METRONIDAZOLE-200MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About DYRADE M TABLET

DYRADE M TABLET belongs to a group of medicines known as antibiotics used to treat various infections caused by bacteria and parasites (amoeba). It is prescribed for the treatment of diarrhea caused by microorganisms Clostridium difficile, Entamoeba histolytica and Giardia lamblia. Additionally, it also treats vaginal and other bacterial infections. Infections caused by amoeba usually happen due to drinking contaminated water or eating food that contains contaminated water. Diarrhea is defined as loose, watery stools or frequent movement of the bowel.

DYRADE M TABLET contains two medicines namely: Metronidazole and Diloxanide. DYRADE M TABLET contains Metronidazole, which is an antibiotic, it treats the infection by damaging the DNA of the organism and kills the bacteria. Diloxanide is an amoebicide. It works inside the large intestine to kill the infection-causing amoeba (parasites). Altogether, DYRADE M TABLET kills the bacteria and parasites. DYRADE M TABLET does not treat a viral infection like the flu or a common cold.

Take DYRADE M TABLET as prescribed by your doctor. You are advised to take DYRADE M TABLET for as long as your doctor has prescribed it for you, depending on your medical condition. Some common side effects of DYRADE M TABLET are nausea, vomiting, upset stomach, loss of appetite, dry mouth and metallic taste. If these effects appear and are bothersome, call your doctor or pharmacist.

Use of DYRADE M TABLET is contraindicated in patients suffering from central nervous system (CNS) diseases like seizures (fits). DYRADE M TABLET should not be used during pregnancy, especially during the first trimester. So, let your doctor know if you are pregnant or planning to get pregnant. You should not breastfeed while taking DYRADE M TABLET as it passes into the breastmilk, and can affect the baby. Do not drive or operate heavy machinery after taking DYRADE M TABLET as it may cause dizziness, drowsiness and make you less alert.

Uses of DYRADE M TABLET

DYRADE M TABLET is used in the treatment of Bacterial Infections, Diarrhea due to Entamoeba histolytica, Giardia lamblia or Clostridium difficile, Vaginal bacterial infections, Dental infections, Post-surgery infections, and Skin bacterial infections.

  • Bacterial Infections: DYRADE M TABLET is effective against a wide range of bacterial infections by inhibiting the growth of harmful bacteria.
  • Diarrhea Due to Parasites or Bacteria: DYRADE M TABLET helps to treat diarrhea caused by Entamoeba histolytica, Giardia lamblia, and Clostridium difficile.
  • Vaginal Infections: DYRADE M TABLET is used to treat bacterial vaginosis and other vaginal infections caused by anaerobic bacteria.
  • Dental Infections: DYRADE M TABLET helps in treating dental abscesses and gum infections by targeting oral anaerobic bacteria.
  • Post-Surgery Infections: DYRADE M TABLET is prescribed to prevent or treat infections that may occur after surgical procedures.
  • Bacterial Skin Infections: DYRADE M TABLET is also effective in treating skin and soft tissue infections caused by susceptible bacteria.
  • Prevents Recurrence: DYRADE M TABLET helps in preventing relapse or recurrence by eliminating the parasite from the intestine and the tissues.

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Directions for Use

  • Tablet: Swallow it as a whole with water; do not crush, break, or chew it.
  • Syrup/suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

DYRADE M TABLET is a broad-spectrum antibiotic that is effective against a wide range of gram-positive and gram-negative bacteria. kills the harmful bacteria and amoeba (Entamoeba histolytica, Giardia lamblia, Clostridium difficile), causing diarrhoea. DYRADE M TABLET contains Metronidazole, which is an antibiotic, it treats the infection by damaging the DNA of the organism and kills the bacteria. Diloxanide is an amoebicide. It works inside the large intestine to kill the infection-causing amoeba (parasites). Altogether, DYRADE M TABLET kills the bacteria and parasites. DYRADE M TABLET does not treat a viral infection like the flu or a common cold.

How DYRADE M TABLET Works

DYRADE M TABLET contains two medicines namely: Metronidazole and Diloxanide. DYRADE M TABLET contains Metronidazole which is an antibiotic , it treats the infection by damaging the DNA of the organism and does killing the bacteria. Diloxanide is an amoebicide. It works inside the large intestine to kill the infection causing amoeba (parasites). Altogether DYRADE M TABLET kills the bacteria and parasites. DYRADE M TABLET does not treat a viral infection like flu or a common cold.

Storage

• Store in a cool and dry place away from sunlight.• Keep DYRADE M TABLET out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Dyrade M Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Inflammation of Vagina needs immediate attention and cannot be ignored.
  • Get a physical examination and prevent wearing clothes that can hold heat and moisture.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Follow your doctor's instructions, and rest well with proper medication.
  • Take a balanced diet and get regular screenings to reduce inflammation.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.

What if I have taken an overdose of DYRADE M TABLET

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

You should immediately report to the doctor in case you have symptoms of dehydration like dehydration dry mouth, excessive thirst, wrinkled skin, little or no urination, dizziness and lightheadedness. In some cases, prolonged intake of DYRADE M TABLET has been associated with leukopenia (low count of white blood cells). Intake of probiotics, prebiotics and plenty of fluids is recommended if you are suffering from dysentery and diarrhea. If you are feeling sick or vomiting, then it is advised to eat simple foods or avoid spicy foods. If a person experiences skin rash or itching after taking DYRADE M TABLET then they should consult with their doctor.

Drug-Drug Interactions

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MetronidazoleAmprenavir
Critical
MetronidazoleDisulfiram
Critical

Drug-Drug Interactions

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MetronidazoleAmprenavir
Critical
How does the drug interact with Dyrade M Tablet:
Co-administration of Amprenavir with Dyrade M Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Taking Dyrade M Tablet with Amprenavir is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience throbbing in the head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetronidazoleDisulfiram
Critical
How does the drug interact with Dyrade M Tablet:
Coadministration of Disulfiram with Dyrade M Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Dyrade M Tablet and Disulfiram together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, confusion, weakness, shortness of breath, or palpitations, contact your doctor. Do not discontinue any medications without consulting a doctor.
MetronidazoleEthanol
Critical
How does the drug interact with Dyrade M Tablet:
Drinking alcohol while taking Dyrade M Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Taking Dyrade M Tablet with Ethanol is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetronidazoleWarfarin
Severe
How does the drug interact with Dyrade M Tablet:
Coadministration of Dyrade M Tablet with warfarin can increase the risk of bleeding.

How to manage the interaction:
There is a possible interaction between Dyrade M Tablet and warfarin, but they can be taken together if a doctor has prescribed them. Consult a doctor if experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not stop using any medications without talking to a doctor.
MetronidazoleBusulfan
Severe
How does the drug interact with Dyrade M Tablet:
Coadministration of Busulfan and Dyrade M Tablet may increase the risk of side effects.

How to manage the interaction:
Taking Dyrade M Tablet and Busulfan together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience unusual bruising or bleeding, fever, diarrhea, sore throat, muscle aches, shortness of breath, or burning during urination, contact a doctor immediately. Do not discontinue the medication without a doctor's advice.
MetronidazoleMebendazole
Severe
How does the drug interact with Dyrade M Tablet:
Coadministration of Dyrade M Tablet with mebendazole may increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Dyrade M Tablet and mebendazole, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms like fever, body ache, painful red rash, cough, peeling of the skin, or Drooling, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
MetronidazoleFluconazole
Moderate
How does the drug interact with Dyrade M Tablet:
Co-administration of Fluconazole together with Dyrade M Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
-Taking Dyrade M Tablet with Fluconazole together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • If you have diarrhea try to drink appropriate amounts of fluids to avoid dehydration.
  • If you have minor diarrhea (less than four stools daily) drinking caffeine-free soft drinks, juices or sport rehydration drinks can be sufficient.
  • If the diarrhoea is more severe, specially formulated rehydration drinks should be taken. Consult your doctor immediately.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

DYRADE M TABLET Substitute

Substitutes safety advice
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Alcohol

Unsafe

You are recommended not to consume alcohol along with DYRADE M TABLET to avoid unpleasant side-effects.

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Pregnancy

Unsafe

DYRADE M TABLET should not be used during pregnancy, especially during the first trimester.

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Breast Feeding

Caution

Take DYRADE M TABLET only when prescribed, it is known to pass on in a limited quantity via breast milk to the child.

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Driving

Caution

DYRADE M TABLET may affect driving as it causes dizziness, so it is advised to avoid driving.

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Liver

Caution

DYRADE M TABLET to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

DYRADE M TABLET to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.

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Children

Caution

Dose to be adjusted and recommended by a child specialist only.

FAQs

DYRADE M TABLET is used to treat infections caused by bacteria and parasites (amoeba). It is prescribed for the treatment of diarrhoea caused by Clostridium difficile, Entamoeba histolytica and Giardia lamblia. Additionally, it also treats vaginal infections.

DYRADE M TABLET is an antibiotic medication so it is advised to complete the full course even if you start to feel better to prevent the return of the infection.

Yes, it could be due to jaundice as in rare cases DYRADE M TABLET can lead to it. Please consult your doctor immediately if the yellowing of the skin persists and does not subside.

You should complete the full course of DYRADE M TABLET as prescribed by your doctor. After completing the full course of DYRADE M TABLET will work. You must take DYRADE M TABLET at the right dose, right times and for the right numbers of days.

DYRADE M TABLET is an antibacterial medicine that acts only against bacterial infections and not viral infections like common cold and flu. You should not take DYRADE M TABLET without prior consulting your doctor. Self-medication is dangerous and can lower the efficacy of DYRADE M TABLET, leading to antibiotic resistance.

If you miss a dose of DYRADE M TABLET, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.

The side effects of DYRADE M TABLET include stomach upset, nausea, vomiting, loss of appetite, dry mouth and metallic taste. Consult the doctor if any of these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - DYR0003

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 10, 2025 | 12:07 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.11318.pdf
  2. https://www.drugs.com/uk/metronidazole-400mg-tablets-bp-leaflet.html
  3. https://www.nhs.uk/medicines/metronidazole/
  4. https://www.medicines.org.uk/emc/files/pil.9238.pdf
  5. https://patient.info/medicine/diloxanide-tablets

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