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Dydrogest 1 mg/10 mg Tablet Combipack 1's is used to treat postmenopausal symptoms and prevent osteoporosis (weak and brittle bones) caused by menopause in women. It contains two female hormones, Estradiol and Dydrogesterone. Estradiol works by replacing the falling levels of estrogen in the body and thus helps to reduce menopause symptoms. Dydrogesterone works by reducing the overgrowth of the womb lining. Together, Dydrogest 1 mg/10 mg Tablet Combipack 1's helps treat postmenopausal symptoms and osteoporosis.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Dydrogest 1 mg/10 mg Tablet Combipack 1's

Dydrogest 1 mg/10 mg Tablet Combipack 1's is a hormone replacement therapy prescribed to relieve uncomfortable symptoms associated with perimenopause and menopause. It is primarily used to treat hot flashes, night sweats, and vaginal dryness while helping to prevent bone loss in postmenopausal individuals.

To achieve the best results, you must take Dydrogest 1 mg/10 mg Tablet Combipack 1's consistently every day, preferably at the same time. You can take this medicine with or without food. Making simple dietary changes and incorporating regular light weight-bearing exercise can also help manage your symptoms more effectively.

While taking this medicine, you may experience mild side effects like headache, breast tenderness, or light spotting. However, if you experience severe symptoms such as sudden chest pain, breathing difficulties, or severe leg swelling, you must contact your doctor immediately.

Talk to your doctor before starting this medicine if you have a history of heart disease, kidney issues, or high blood pressure. Cardiovascular risks vary depending on your age and time since menopause onset; health benefits generally outweigh risks when hormone therapy is started under age 60 or within 10 years of menopause onset. Do not take this if you have active blood clots, unexplained vaginal bleeding, a history of breast cancer, or severe liver damage.

This medicine can interact with certain anti-seizure medicines and herbal remedies, which may reduce its effectiveness. Avoid smoking while taking this medicine as it significantly increases your risk of blood clots. If you are pregnant or breastfeeding, you should not take this medicine, and elderly individuals should consult their healthcare provider before use.

Uses of Dydrogest 1 mg/10 mg Tablet Combipack 1's

Dydrogest 1 mg/10 mg Tablet Combipack 1's is used to treat the following conditions:

  • Menopause symptom relief: Dydrogest 1 mg/10 mg Tablet Combipack 1's helps reduce hot flashes, night sweats, vaginal dryness, sleep disturbances, and mood changes (such as mild anxiety, low mood, or irritability) caused by declining hormone levels during perimenopause and menopause.
  • Osteoporosis prevention: It helps maintain bone density and prevent fractures in postmenopausal individuals who are at a higher risk of bone thinning.

 

Key Benefits

Dydrogest 1 mg/10 mg Tablet Combipack 1's provides reliable support to help manage menopausal symptoms and protect your long-term health. By restoring hormonal balance, this medicine provides several key health benefits:

  • Relief from Menopausal Discomforts: This medicine provides significant relief from the physical discomforts of menopause, helping you return to your normal daily routine without the disruption of sudden hot flashes or night sweats (with initial relief typically noticed within 2 to 4 weeks of starting treatment). It also improves vaginal comfort, making daily activities and intimacy pain-free.
  • Long-Term Skeletal Protection: Beyond symptom control, it offers long-term protection for your skeletal health. By slowing down bone loss, it reduces the risk of painful bone fractures, allowing you to maintain active, independent movement as you age.

Directions for Use

  • Dydrogest 1 mg/10 mg Tablet Combipack 1's can be taken with or without food as advised by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Dydrogest 1 mg/10 mg Tablet Combipack 1's as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Dydrogest 1 mg/10 mg Tablet Combipack 1's Works

Dydrogest 1 mg/10 mg Tablet Combipack 1's contains estradiol and dydrogesterone, which work together as a combination hormone replacement therapy designed to mimic the natural hormones in your body and restore balance during and after menopause. Estradiol is an estrogen. As menopause approaches, your body's natural estrogen levels drop, causing symptoms like hot flashes and vaginal dryness. Estradiol replaces the missing estrogen to alleviate these symptoms. Dydrogesterone is a progestogen. When estrogen is taken alone, it can cause the lining of the womb to grow excessively. Dydrogesterone protects your womb by preventing this overgrowth, significantly reducing the risk of uterine complications.
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Alcohol

Unsafe

Avoid consumption of alcohol with Dydrogest 1 mg/10 mg Tablet Combipack 1's as it may increase the risk of breast cancer and delay healing.

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Pregnancy

Unsafe

Dydrogest 1 mg/10 mg Tablet Combipack 1's is only recommended for postmenopausal women. Therefore, consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding. Hence, inform your doctor before taking Dydrogest 1 mg/10 mg Tablet Combipack 1's if you are breastfeeding. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Safe

Dydrogest 1 mg/10 mg Tablet Combipack 1's may not affect your ability to drive.

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Liver

Unsafe

Dydrogest 1 mg/10 mg Tablet Combipack 1's should not be used in patients with liver diseases. Inform your doctor if you have/had a history of liver disease before starting treatment with this medicine.

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Kidney

Caution

Dydrogest 1 mg/10 mg Tablet Combipack 1's should be used with caution in patients with severe kidney diseases. Hence, if you have a pre-existing or a history of kidney disease, inform your doctor before taking Dydrogest 1 mg/10 mg Tablet Combipack 1's. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Dydrogest 1 mg/10 mg Tablet Combipack 1's is recommended for use in post-menopause women.

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Heart

Caution

Inform your doctor before receiving the Dydrogest 1 mg/10 mg Tablet Combipack 1's if you have heart disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor if you have any concerns regarding the use of Dydrogest 1 mg/10 mg Tablet Combipack 1's in elderly patients.

What if I have taken an overdose of Dydrogest 1 mg/10 mg Tablet Combipack 1's

If you accidentally take too many tablets, seek immediate medical attention or contact a poison control centre. Symptoms of an overdose may include nausea, vomiting, or withdrawal bleeding.

Diet & Lifestyle Advise

  • Prioritise Calcium and Vitamin D: Eat calcium-rich foods like yoghurt, leafy greens, and almonds, or talk to your doctor about supplements to protect your bones.
  • Engage in Weight-Bearing Exercise: Walking, jogging, or resistance training helps strengthen bones and supports joint health.
  • Identify and Avoid Triggers: Limit your intake of caffeine, alcohol, and spicy foods, as these are known to trigger sudden hot flashes.
  • Avoid Smoking: Stop smoking entirely, as nicotine increases your risk of developing blood clots while on hormone replacement therapy.
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How Soon It Starts Working

The time required for Dydrogest 1 mg/10 mg Tablet Combipack 1's to start to work: The time required for Dydrogest 1 mg/10 mg Tablet Combipack 1's to show its action is unknown. The time for which the effects of Dydrogest 1 mg/10 mg Tablet Combipack 1's last: The duration of action for Dydrogest 1 mg/10 mg Tablet Combipack 1's is unknown.

What if you forget to take Dydrogest 1 mg/10 mg Tablet Combipack 1's

If you miss a dose, take it as soon as you remember. However, if it has been more than 12 hours since your scheduled time, skip the missed dose and take your next dose at the regular time. Do not take a double dose to make up for a forgotten tablet.

Storage

•Store Dydrogest 1 mg/10 mg Tablet Combipack 1's tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original blister packaging to protect them from light and moisture.

Drug Warnings

  • Perform regular breast screenings: Perform monthly breast self-exams and attend all scheduled mammogram appointments as recommended by your doctor.
  • Monitor blood pressure: Monitor your blood pressure regularly, as hormone therapy can sometimes cause it to rise.
  • Plan for surgery or bed rest: If you have an upcoming surgery or need prolonged bed rest, inform your doctor; you may need to stop taking Dydrogest 1 mg/10 mg Tablet Combipack 1's temporarily to reduce blood clot risks.
  • Schedule regular reviews: Have at least an annual check-up with your doctor to review your treatment, re-evaluate benefits and risks, and ensure you remain on the lowest effective dose.
  • Not a contraceptive: Remember that Dydrogest 1 mg/10 mg Tablet Combipack 1's is not a contraceptive and will not prevent pregnancy; consult your doctor if you require birth control.
  • Report unusual bleeding: Report any unexpected, heavy, or persistent vaginal bleeding to your doctor immediately. Your doctor may arrange an ultrasound or endometrial evaluation to verify that your uterine lining remains healthy.

verifiedApollotooltip
  • Epilepsy medicines: Medicines for epilepsy (such as carbamazepine or phenobarbital) may speed up the breakdown of Dydrogest 1 mg/10 mg Tablet Combipack 1's, making it less effective.
  • Tuberculosis medicines: Tuberculosis medicines (like rifampicin) can decrease the hormone levels in your blood.
  • Herbal supplements: Herbal preparations containing St. John's wort can reduce the therapeutic effects of this medicine.
     

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verifiedApollotooltip
  • Grapefruit juice: Avoid drinking large amounts of grapefruit juice, as it can increase the concentration of active hormones in your body, raising the risk of side effects. 

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[HORMONES]

FAQs

Dydrogest 1 mg/10 mg Tablet Combipack 1's is used for treatment and prevention of hot flashes and osteoporosis in postmenopausal women.
Dydrogest 1 mg/10 mg Tablet Combipack 1's contains two female hormones, Estradiol and Dydrogesterone. Estradiol works by replacing the falling levels of estrogen in the body and thus helps to reduce menopause symptoms. Dydrogesterone works by reducing the overgrowth of the womb lining. Also, Dydrogest 1 mg/10 mg Tablet Combipack 1's is used as prophylaxis in preventing postmenopausal osteoporosis.
Dydrogest 1 mg/10 mg Tablet Combipack 1's is not a contraceptive. Dydrogest 1 mg/10 mg Tablet Combipack 1's is a hormone replacement therapy. Therefore, if you are less than 50 years old or if it is less than 12 months since your last period, you are advised to use additional contraceptive measures to avoid pregnancy. However, discuss with a doctor if you have any concerns regarding this.
Dydrogest 1 mg/10 mg Tablet Combipack 1's may cause irregular bleeding or spotting (drops of blood) during the first 3 to 6 months of taking Dydrogest 1 mg/10 mg Tablet Combipack 1's. However, if the bleeding or spotting continues for more than six months or after discontinuing Dydrogest 1 mg/10 mg Tablet Combipack 1's, please consult a doctor immediately.
Dydrogest 1 mg/10 mg Tablet Combipack 1's is a combination medication that contains two hormones, Estradiol and Dydrogesterone. It is used for hormone replacement therapy (HRT) in women who have gone through menopause to relieve symptoms like hot flashes and to protect against bone loss.
Take Dydrogest 1 mg/10 mg Tablet Combipack 1's at the dose and timing determined by your doctor. Swallow the medication as a whole with a glass of water. Do not crush, chew, or break it. For better results, take this medication at the same time every day.
If you miss a dose of Dydrogest 1 mg/10 mg Tablet Combipack 1's, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and take your next dose at the usual time. Do not take two doses at once to make up for a missed dose. If you miss multiple doses, contact your doctor for guidance.
While taking Dydrogest 1 mg/10 mg Tablet Combipack 1's, some individuals may experience common side effects such as stomach pain, headache, breast pain or tenderness, and back pain. It's important to note that not everyone will experience these side effects, and in most cases, they are mild and temporary, resolving on their own over time without requiring medical attention. However, if these side effects persist or worsen, it's essential to consult your doctor for further guidance and support to ensure your safety and well-being.
You can take Dydrogest 1 mg/10 mg Tablet Combipack 1's either with or without food. Taking it with food or a light snack can help if you experience mild nausea when starting the medicine. Talk to your doctor or pharmacist if you have ongoing stomach discomfort.
Moderate alcohol consumption is generally acceptable, but excessive drinking can alter hormone levels and increase your risk of certain side effects. It is best to limit alcohol intake while on hormone replacement therapy. Talk to your doctor about what is safe for you.
Some people may experience mild fluid retention or minor weight fluctuations when starting hormone therapy. However, significant weight gain is not a typical direct effect of this medicine. Talk to your doctor or pharmacist if you notice sudden or unusual weight changes.
The duration of treatment depends on your symptoms and overall health risks. Doctors generally recommend using hormone therapy at the lowest effective dose for the shortest duration necessary. Talk to your doctor regularly to review whether you still need the medicine.
You should not stop taking Dydrogest 1 mg/10 mg Tablet Combipack 1's without consulting your healthcare provider first. Stopping suddenly can cause your menopause symptoms to return. Talk to your doctor about how to safely discontinue the medicine if you no longer need it.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

D' Block, 3rd Floor, Gillander House, Netaji Subhas Road, Kolkata - 700001 (Wb)
Other Info - DYD0105
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