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Duvadilan Injection 2 ml is used in the treatment of peripheral vascular diseases such as Raynaud's phenomenon, cerebral vascular insufficiency, arteriosclerosis (hardening of the arteries), Buerger's disease. This medicine is also used in the prevention of premature labour. It contains isoxsuprine which helps relax and widen the blood vessels, and thus improves blood circulation.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Duvadilan Injection 2 ml

Duvadilan Injection 2 ml is a sterile injection used to treat serious bacterial infections, including certain types of pneumonia and severe skin infections. It belongs to a class of antibiotics that stop the growth of bacteria, helping your body fight off the infection. Doctors reserve this medicine for complicated infections, especially those resistant to other antibiotics.

Because this medicine is given directly into a vein, healthcare professionals usually give it at regular intervals to maintain a steady level in your blood. You do not need to worry about taking it with food, as the injection bypasses the stomach. Eating a balanced diet and staying well-hydrated can support your immune system during treatment.

While using Duvadilan Injection 2 ml, you may experience mild side effects like diarrhoea, headaches, or nausea. However, you must contact your healthcare provider immediately if you experience severe symptoms such as blurred vision, persistent diarrhoea, or unusual bruising.

Talk to your doctor before starting this medicine if you have high blood pressure, thyroid problems, or a history of seizures. Do not take this if you are currently taking, or have taken in the last two weeks, a monoamine oxidase inhibitor (MAOI) for depression.

Duvadilan Injection 2 ml can interact with certain foods containing tyramine (like aged cheeses) and medicines that increase serotonin levels, which can cause a dangerous rise in blood pressure. It is also important to avoid alcohol during treatment, and you should consult your doctor if you are pregnant, breastfeeding, or an older adult.
 

Uses of Duvadilan Injection 2 ml

Duvadilan Injection 2 ml is used to treat serious bacterial infections. The detailed uses of Duvadilan Injection 2 ml are as follows:

  • Pneumonia: Duvadilan Injection 2 ml helps clear severe lung infections, including hospital-acquired and community-acquired pneumonia caused by susceptible bacteria.
  • Complicated skin and soft tissue infections: Duvadilan Injection 2 ml targets and eliminates bacteria causing deep skin infections, helping the tissue heal properly.
  • Vancomycin-resistant Enterococcus (VRE) infections: Duvadilan Injection 2 ml is highly effective against specific drug-resistant bacterial strains that other antibiotics cannot treat.

 

Key Benefits

Duvadilan Injection 2 ml provides critical therapeutic benefits for patients facing hard-to-treat bacterial infections:

  • Targeted treatment of resistant bacteria: It overcomes bacterial resistance, giving patients a reliable treatment option when standard antibiotics fail.
  • Faster recovery from severe illness: By rapidly stopping bacterial growth, it helps reduce fever, chest discomfort, and skin inflammation, allowing you to regain your strength sooner.
  • Direct delivery into the bloodstream: The parenteral route ensures 100% of the medication is immediately available to fight infection throughout the body.
     
Side effects of Duvadilan Injection 2 ml
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Duvadilan Injection 2 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Duvadilan Injection 2 ml Works

Duvadilan Injection 2 ml contains linezolid, which works by stopping bacteria from growing and multiplying. It does this by binding to a specific part of the bacterial cell (the ribosome) and preventing it from making essential proteins that the bacteria need to survive and replicate. Without these vital proteins, the bacteria cannot spread or maintain their structure. This stops the infection in its tracks, allowing your body's natural immune system to easily target and clear the remaining bacteria.
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Alcohol

Caution

Avoid alcohol consumption while on treatment with Duvadilan Injection 2 ml as it might cause increased dizziness.

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Pregnancy

Caution

Duvadilan Injection 2 ml should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant. Your doctor will weigh the benefits and potential risks before prescribing Duvadilan Injection 2 ml.

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Breast Feeding

Caution

Duvadilan Injection 2 ml is not recommended to be used in breastfeeding unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Duvadilan Injection 2 ml.

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Driving

Caution

Drive with caution; Duvadilan Injection 2 ml may cause dizziness.

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Liver

Caution

Inform your doctor before receiving the Duvadilan Injection 2 ml if you have a history of liver problems. Your doctor may adjust the dose of this medicine based on your liver condition.

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Kidney

Caution

Inform your doctor before receiving the Duvadilan Injection 2 ml if you have a history of kidney conditions. Your doctor may adjust the dose of this medicine based on your kidney condition.

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Children

Unsafe

Duvadilan Injection 2 ml is not recommended for children as the safety and effectiveness of Duvadilan Injection 2 ml have not been established.

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Heart

Caution

Duvadilan Injection 2 ml should be used cautiously in patients with heart conditions. It may cause increased heart rate (tachycardia) and interact with other cardiovascular medications, so close monitoring by a doctor is essential.

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Geriatrics

Caution

Geriatric patients can receive Duvadilan Injection 2 ml, but it may be more sensitive to side effects like low blood pressure or increased heart rate. Careful monitoring and individualized dosing are essential to ensure safety.

What if I have taken an overdose of Duvadilan Injection 2 ml

If you receive too much of this medicine, or experience severe dizziness, vomiting, or muscle tremors, seek emergency medical care immediately.

Diet & Lifestyle Advise

  • Avoid foods high in tyramine: While using Duvadilan Injection 2 ml, avoid aged cheeses, air-dried or cured meats, red wine, tap beers, sauerkraut, and soy sauce. These foods can react with the medicine and cause a dangerous spike in your blood pressure.
  • Stay hydrated: Drink plenty of water throughout your treatment to help your kidneys process the medication and to prevent dehydration, especially if you experience mild diarrhoea.
  • Limit caffeine intake: High amounts of caffeine from coffee, tea, energy drinks, or chocolate can increase the risk of elevated blood pressure when combined with this medicine.
  • Get plenty of rest: Your body needs energy to fight off a serious infection, so prioritise sleep and avoid strenuous physical activities during your recovery.
     
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How Soon It Starts Working

The time required for Duvadilan Injection 2 ml to start to work: Duvadilan Injection 2 ml ideally shows its action within 10 minutes after administration. The time for which the effects of Duvadilan Injection 2 ml last: The effect of Duvadilan Injection 2 ml lasts for 6 to 8 hours.

What if you forget to take Duvadilan Injection 2 ml

Since Duvadilan Injection 2 ml is usually given by a healthcare provider, a missed dose is unlikely. If you are injecting it at home and miss a scheduled infusion, contact your doctor or nurse immediately for guidance. Do not double the dose to make up for a missed one.

Storage

• Store Duvadilan Injection 2 ml infusion bags at room temperature, ideally between 20°C and 25°C (68°F to 77°F).
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Inspect the solution before use: Always check the infusion bag for leaks, cloudiness, or floating particles. If you notice any of these, do not inject it and contact your pharmacist.
  • Monitor your blood counts: If you use this medicine for more than two weeks, your doctor will likely order weekly blood tests to check your platelet and red blood cell levels.
  • Check your vision: Tell your doctor immediately if you experience any changes in your eyesight, especially if your treatment lasts longer than 28 days.
  • Watch for nerve symptoms: Report any numbness, tingling, or weakness in your hands or feet, as these can be signs of nerve damage.
  • Rotate injection sites: If you are injecting this at home, rotate the injection site as directed by your nurse to prevent irritation or vein inflammation.

Drug-Drug Interactions

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  • Antidepressants (such as SSRIs, SNRIs, and MAOIs): Combining these with Duvadilan Injection 2 ml can lead to a life-threatening condition called serotonin syndrome, causing confusion, high fever, and muscle stiffness.
  • Decongestants and cold medicines: Medications containing pseudoephedrine or phenylephrine can cause a severe, sudden increase in blood pressure when taken with Duvadilan Injection 2 ml.
  • Migraine medications (triptans): These can also increase the risk of serotonin syndrome.
     

Drug-Drug Interactions

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How does the drug interact with Duvadilan Injection 2 ml:
Co-administration of Duvadilan Injection 2 ml and tizanidine may lead to low blood pressure, which may result in side effects.

How to manage the interaction:
Taking Tizanidine with Duvadilan Injection 2 ml together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience headache, lightheadedness, fainting, changes in pulse or heart rate, consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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  • Tyramine-rich foods: Foods like aged cheese, smoked meats, yeast extracts, and draft beer can cause a dangerous rise in blood pressure.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[VASODILATORS]

FAQs

Duvadilan Injection 2 ml belongs to a class of medication called vasodilators used to treat and prevent peripheral vascular diseases such as Raynaud's phenomenon, cerebral vascular insufficiency (poor blood flow to the brain), arteriosclerosis (hardening of the arteries), Buerger's disease (a condition that causes small and medium arteries and veins to constrict blood flow to the hands and feet) and other conditions involving poor blood flow in the blood vessels.
Duvadilan Injection 2 ml acts by relaxing and widening blood vessels, thereby increasing the blood flow to the organs, muscles and blocked nerves of the body.
Duvadilan Injection 2 ml relaxes smooth muscles of the uterus and prevents premature labour.
Please inform your doctor if you are taking Duvadilan Injection 2 ml and are due to undergo surgery. Your doctor may advise you to stop using the Duvadilan Injection 2 ml before the surgery.
Orthostatic hypotension could be a side-effect of Duvadilan Injection 2 ml. Orthostatic hypotension is a quick drop in blood pressure that makes you feel lightheaded when you stand up. If you encounter this, lie down and rise up gradually only when you feel better rather than attempting to stand up suddenly or begin walking. It is advised to monitor your blood pressure regularly while on treatment with this medicine.
Duvadilan Injection 2 ml should be administered by a healthcare professional. The dosage of Duvadilan Injection 2 ml may vary based on your health condition. Therefore, follow your doctor's prescribed dose and duration for the best results. Do not self-administer.
Duvadilan Injection 2 ml causes side effects such as weakness, dizziness, irregular heartbeats, stomach upset, and vomiting. However, these side effects do not require any medical requirements, as they will gradually reduce over time. Please, contact a doctor if these persist for longer durations.
You should only use Duvadilan Injection 2 ml during pregnancy if the potential benefit justifies the potential risk to the unborn baby. Talk to your doctor to weigh the benefits and risks.
Your doctor may order weekly blood tests, especially if you are on this medicine for more than 10 to 14 days, to monitor your blood cell counts, as this medicine can temporarily lower them. Talk to your doctor if you have concerns about these tests.
No, you should avoid alcohol, especially draft beers and red wine, because they contain high levels of tyramine, which can cause a severe increase in your blood pressure when combined with this medicine. Talk to your doctor for more safety advice.
If you notice redness, swelling, pain, or warmth around the injection site, contact your healthcare provider right away, as these could be signs of skin irritation or infection. Talk to your doctor or nurse for proper care steps.
Yes, long-term use of Duvadilan Injection 2 ml (usually more than 28 days) has been linked to nerve problems, such as numbness or tingling in the hands and feet. Talk to your doctor immediately if you experience these symptoms.
Yes, you must avoid foods rich in tyramine, such as aged cheeses, cured meats, and soy sauce, to prevent a dangerous rise in blood pressure. Talk to your doctor or pharmacist for a complete list of foods to avoid.
No, Duvadilan Injection 2 ml is an antibiotic and only works against bacterial infections. It will not treat viral infections like the common cold or flu. Talk to your doctor to get an accurate diagnosis for your symptoms.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Solvate Laboratories Pvt.Ltd., C-57, IIIrd Floor, Vikas Marg, Preet Vihar, Delhi-110092
Other Info - DUV0001
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