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compositionComposition:MEFENAMIC ACID-100MG+PARACETAMOL-250MG
prescriptionPrescription Medicine
Duoflam DS Syrup 60 ml

Duoflam DS Syrup is used to treat fever and mild to moderate pain in children. The medicine provides effective pain relief and helps improve comfort in conditions involving inflammation and fever.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

MEFENAMIC ACID-100MG+PARACETAMOL-250MG

Manufacturer/Marketer :

Sigma Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Duoflam DS Syrup

Duoflam DS Syrup is used to relieve pain and fever. It helps relieve muscle and dental pain in children. Acute pain is short-term and caused by damage to the tissues of the muscle, bone, or other organs. Chronic pain lasts for a long duration and is caused by pathologies like nerve damage, etc.

Duoflam DS Syrup is a combination of mefenamic acid and paracetamol. Mefenamic acid works by blocking the effect of a chemical known as prostaglandin. Paracetamol inhibits the synthesis of a chemical messenger (prostaglandin) and promotes heat loss (through sweating).

Duoflam DS Syrup may cause certain side effects in your child, such as abdominal pain, cold-like nose symptoms (in children), or diarrhoea (in children). These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your paediatrician.

Duoflam DS Syrup is intended for pediatric use only. Avoid giving Duoflam DS Syrup to your child if she/he is allergic to any of its components. Keep your doctor informed about your child’s health condition, including his current medications and medical history, to rule out any side effects/interactions.

Uses of Duoflam DS Syrup

Duoflam DS Syrup is used in the treatment of pain and fever in children. The detailed uses of Duoflam DS Syrup are as follows:

  • Pain Relief: Duoflam DS Syrup is commonly used to alleviate moderate to severe pain, including headaches, dental pain, and muscle aches.
  • Fever Reduction: Duoflam DS Syrup can be effective in lowering fever, making it suitable for treating febrile conditions associated with various infections.

Key Benefits

  • Relieves pain: Helps reduce mild to moderate pain such as headache, toothache, and muscle pain.
  • Reduces fever: Helps lower high body temperature during infections.
  • Reduces inflammation: Helps decrease swelling and inflammation associated with pain.
  • Provides quick comfort: Helps improve overall comfort in conditions causing pain and fever.

Directions for Use

  • Duoflam DS Syrup can be given to your child with food to prevent stomach upset.
  • Typically, it is given 2-3 times a day. However, follow the doctor's instructions regarding the required dosage and timing of this medication for optimal effectiveness.
  • Shake the bottle well before each use.
  • Give your child the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided with the pack.
  • Avoid using regular household spoons, as they may not measure the dose correctly.

How Duoflam DS Syrup Works

Duoflam DS Syrup is a combination medicine containing two drugs, namely, Mefenamic acid (NSAID) and Paracetamol (antipyretic). • Mefenamic acid works by blocking the effect of a chemical known as prostaglandin, which is responsible for inducing pain and inflammation in the body. • Paracetamol lowers the elevated body temperature and mild pain by inhibiting the synthesis of a chemical messenger (prostaglandin) and promoting heat loss (through sweating) that helps reset the hypothalamic thermostat.
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Alcohol

Not applicable

-

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Pregnancy

Not applicable

-

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Breast Feeding

Not applicable

-

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Driving

Not applicable

-

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Liver

Consult your doctor

Please consult your doctor if your child has a liver impairment or if you have any concerns regarding this.

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Kidney

Consult your doctor

Please consult your doctor if your child has a kidney impairment or if you have any concerns regarding this.

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Children

Safe if prescribed

Duoflam DS Syrup is safe for children over 6 months of age when prescribed by a doctor. Your paediatrician will decide the dose of the medicine. Do not give your child more than the recommended dose.

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Heart

Caution

If your child has a heart condition, Duoflam DS Syrup should only be given under a doctor’s supervision.

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Geriatrics

Not applicable

Duoflam DS Syrup is specifically for children's use and is not meant for geriatric patients.

What if I have taken an overdose of Duoflam DS Syrup

In case the child accidentally takes an overdose of Duoflam DS Syrup than prescribed and shows some signs of unwanted side effects such as CNS toxicity, especially convulsions, it is necessary to take the patient to an emergency department at the nearest medical facility to receive treatment. Timely medical support helps patients overcome dangerous situations.

Diet & Lifestyle Advise

Diet

  • Include food rich in antioxidants, such as berries, spinach, kidney beans, dark chocolate, etc in your child's diet.
  • Make your child to drink more fluids to avoid dehydration.
  • Eat a balanced diet that includes fruits, vegetables, and whole grains to support better recovery.

Lifestyle changes

  • Sleeping for 7-9 hours each night can help your child stay fit and safe.
  • Allow light activities only and avoid strenuous play until the child feels better.

Have a query?

How Soon It Starts Working

  • The time required for Duoflam DS Syrup to start to work: Duoflam DS Syrup ideally shows its action within 30 to 60 minutes after administration.
  • The time for which the effects of Duoflam DS Syrup last: The effect of Duoflam DS Syrup lasts for 12 hours.

What if you forget to take Duoflam DS Syrup

If you forgot to give a dose of Duoflam DS Syrup to your child, give it as soon as you remember. If it is almost time for the next dose, skip the missed dose and follow the regular schedule. Do not give a double dose to make up for the missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep Duoflam DS Syrup out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Avoid giving Duoflam DS Syrup to your child if they are allergic to it.
  • Keep your paediatrician informed about your child’s health condition, including their previous medications and medical history, to rule out any side effects or interactions.
  • Before administration, inform the paediatrician about all the OTC medicines, including other vitamin supplements, that your child is taking.
  • It is advised not to exceed the prescribed dose of medicine.
  • Also, inform your doctor if your child has liver or kidney-related issues before administration.
  • Duoflam DS Syrup is intended for use by children. Hence, adults, pregnant women, and breastfeeding mothers should avoid taking this medicine.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Inform your paediatrician if your child is taking any medicines, or vitamin supplements before givinh Duoflam DS Syrup.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor before administering Duoflam DS Syrup if your child has any history of

  • Kidney disease
  • Liver disease.
Paracetamol + Mefenamic acidKetorolac
Critical
Paracetamol + Mefenamic acidTacrolimus
Severe

Drug-Drug Interactions

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Paracetamol + Mefenamic acidKetorolac
Critical
How does the drug interact with Duoflam DS Syrup 60 ml:
Coadministration of Duoflam DS Syrup 60 ml with Ketorolac can increase the risk or severity of bleeding and ulcers.

How to manage the interaction:
Although there is an interaction between Duoflam DS Syrup 60 ml and ketorolac, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Paracetamol + Mefenamic acidTacrolimus
Severe
How does the drug interact with Duoflam DS Syrup 60 ml:
Coadministration of Duoflam DS Syrup 60 ml with tacrolimus can increase the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between Duoflam DS Syrup 60 ml and tacrolimus, it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Paracetamol + Mefenamic acidDeferasirox
Severe
How does the drug interact with Duoflam DS Syrup 60 ml:
Coadministration of Duoflam DS Syrup 60 ml with deferasirox can increase the risk or severity of bleeding and kidney problems.

How to manage the interaction:
Although there is an interaction between Duoflam DS Syrup 60 ml and deferasirox, it can be taken if your doctor has advised it. However, if you experience of increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Paracetamol + Mefenamic acidDanaparoid
Severe
How does the drug interact with Duoflam DS Syrup 60 ml:
Taking danaparoid with Duoflam DS Syrup 60 ml can increase the risk of bleeding complications.

How to manage the interaction:
Although there is an interaction between Duoflam DS Syrup 60 ml and danaparoid, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
Paracetamol + Mefenamic acidMethotrexate
Severe
How does the drug interact with Duoflam DS Syrup 60 ml:
Coadministration of Duoflam DS Syrup 60 ml with methotrexate may increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although there is an interaction between Duoflam DS Syrup 60 ml and methotrexate, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience mouth ulcers, vomiting; diarrhea, less desire to eat, joint pain, yellow discoloration of skin and eyes, shortness of breath or dizziness . Do not discontinue any medications without consulting a doctor.
Paracetamol + Mefenamic acidAcalabrutinib
Severe
How does the drug interact with Duoflam DS Syrup 60 ml:
Coadministration of acalabrutinib with Duoflam DS Syrup 60 ml can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between acalabrutinib and Duoflam DS Syrup 60 ml, they can be taken together if prescribed by a doctor. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Paracetamol + Mefenamic acidIbrutinib
Severe
How does the drug interact with Duoflam DS Syrup 60 ml:
Co-administration of Duoflam DS Syrup 60 ml with ibrutinib can increase the risk or severity of bleeding, leading to serious blood loss.

How to manage the interaction:
Although there is an interaction between Duoflam DS Syrup 60 ml and ibrutinib, it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Paracetamol + Mefenamic acidFondaparinux
Severe
How does the drug interact with Duoflam DS Syrup 60 ml:
Taking paracetamol + mefenamic with fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Duoflam DS Syrup 60 ml and fondaparinux, it can be taken if your doctor has advised it. However, if you experience bleeding or bruising, feeling dizzy or lightheaded, dark or bloody stools, headache, weakness contact a doctor right away. Do not stop using any medications without first talking to your doctor.
Paracetamol + Mefenamic acidRivaroxaban
Severe
How does the drug interact with Duoflam DS Syrup 60 ml:
Coadministration of Duoflam DS Syrup 60 ml with rivaroxaban can increase the risk or severity of bleeding.

How to manage the interaction:
Although there is an interaction between Duoflam DS Syrup 60 ml and rivaroxaban, it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Paracetamol + Mefenamic acidEnoxaparin
Severe
How does the drug interact with Duoflam DS Syrup 60 ml:
Taking Duoflam DS Syrup 60 ml with enoxaparin can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Duoflam DS Syrup 60 ml and enoxaparin, they can be taken together if prescribed by a doctor. However, if you experience bruising, swelling, vomiting, headache, dizziness, weakness, or blood in urine or stool, contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANALGESIC AND ANTIPYRETIC AGENT]

FAQs

Duoflam DS Syrup is used to treat Pain and Fever.

Mefenamic acid (NSAID) and Paracetamol (antipyretic). Mefenamic acid works by blocking the effect of a chemical known as prostaglandin, which is responsible for inducing pain and inflammation in our body. Paracetamol lowers elevated body temperature and mild pain by inhibiting the synthesis of a chemical messenger (prostaglandin) and promoting heat loss (through sweating).

Duoflam DS Syrup can cause diarrhea as a side effect in some children. If your child has diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your paediatrician tells you to.

The side effects of Duoflam DS Syrup include nausea, indigestion, stomach pain and diarrhoea. If these side effects persist or worsen, please consult your doctor.

Yes, Duoflam DS Syrup is safe to use in the prescribed dose and duration. The patient should follow the doctor’s recommendations.

Duoflam DS Syrup is generally used for short term and can be stopped when the pain is relieved. However, it should be continued for as long as it is advised by your doctor.

Yes, the use of Duoflam DS Syrup can cause nausea and vomiting. Taking it with food, milk, or antacids can avoid nausea. Avoid giving your child fried or fatty foods along with Duoflam DS Syrup. If vomiting occurs, let your child drink plenty of water or other fluids by taking small and frequent sips. If vomiting persists and if you notice signs of dehydration, such as a low frequency of urination and dark colored and strong-smelling urine, consult your doctor. Do not give any other medicine to your child without consulting your doctor.

Duoflam DS Syrup is contraindicated in patients with known allergy to painkillers (NSAIDS) or any of the components or excipients of this medicine. Also, let the doctor know if the patient has kidney or liver disease.

You are recommended to consult your doctor before giving Duoflam DS Syrup to your child with vitamin B-complex or other supplements.

Yes, the long-term use of Duoflam DS Syrup can cause damage to the kidneys. Normal kidneys produce prostaglandins, a chemical that protects them from damage. Long-term use of painkillers lowers the prostaglandin levels in the body, leading to kidney damage. Therefore, painkillers are not recommended for patients with underlying kidney disease.

No, taking higher than the recommended dose of Duoflam DS Syrup may increase the risk of side effects such as nausea, vomiting, indigestion, heartburn, diarrhoea and can also harm the kidneys when used for an extended period of time. If your child's pain is not relieved by the recommended doses or if your child experiences increased severity of pain, please consult your doctor.

Store Duoflam DS Syrup below 25°C. Protect from light. Keep it out of reach and sight of children.

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

  • Dr Aneela Siddabathuni

    MPharma., PhD

Last Updated

Doctor imageWe provide you with authentic, trustworthy and relevant information

Country of origin

INDIA

Manufacturer/Marketer address

Sigma House, 43 S Wadala, Wadala West, Wadala, Mumbai, Maharashtra 400031
Other Info - DUO0145
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