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Duo-Cytra 200Ml Solution is a combination medicine used in the treatment of Kidney stones and renal tubular acidosis. This medicine works by increasing the urinary pH, potassium, magnesium, and citric acid levels; thus preventing the crystallization, growth, and accumulation of stone-forming salts. It helps provide relief from a burning sensation during urination. Common side effects include abdominal discomfort, diarrhoea, nausea, and vomiting.

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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Manufacturer/Marketer :

RPG Life Sciences Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Duo-Cytra 200Ml Solution

To get the best results, you must take it consistently at the exact times prescribed by your doctor. It is typically taken with or after meals to help prevent an upset stomach, and if it is in liquid form, it should be diluted with water. Alongside this medicine, drinking plenty of water and reducing your salt intake are essential lifestyle changes that support your treatment.

While using this medicine, you may experience mild stomach-related side effects like nausea or mild diarrhea. However, you must contact your doctor immediately if you experience severe symptoms, such as severe abdominal pain, muscle weakness, or an irregular heartbeat.

If you are pregnant, planning to become pregnant, or breastfeeding, tell your doctor before starting this medicine. Your doctor will carefully weigh the benefits and possible risks and may monitor you more closely during treatment if needed. Before starting this medicine, tell your doctor if you have heart disease, kidney problems, stomach ulcers, or a urinary tract infection (UTI). Your doctor will decide whether this medicine is suitable for you and may recommend additional monitoring if needed.

Older adults, especially those with reduced kidney function, may need closer monitoring or dose adjustments because their bodies may not remove potassium as efficiently. Follow your doctor's instructions carefully and attend all recommended follow-up appointments.

Uses of Duo-Cytra 200Ml Solution

Your doctor may recommend Duo-Cytra 200Ml Solution to help:

  • Kidney stone prevention: Duo-Cytra 200Ml Solution Helps reduce the risk of calcium oxalate stones and also makes the urine less acidic, which can help reduce the formation of uric acid stones. Although urine alkalinization may also help in cystine stones, people with cystinuria usually require additional treatments recommended by their doctor.
  • Renal tubular acidosis (a kidney condition in which the kidneys cannot remove acid from the body properly): It helps balance urine chemistry and reduce excess acid.
  • Hypocitraturia (low citrate levels in the urine, which increases the risk of kidney stones): It raises citrate levels in the urine, helping stop crystals from joining together to form painful kidney stones.

Key Benefits

When used as directed as part of your treatment plan, Duo-Cytra 200Ml Solution may provide the following benefits:

  • Helps Prevent Kidney Stones: It provides effective relief and protection by targeting the chemical environment where kidney stones grow.
  • Reduces Stone Formation: By making your urine less acidic (raising its pH) and increasing citrate levels, it helps stop stones from forming, reducing the risk of the severe pain and discomfort caused by passing kidney stones.It also supports long-term kidney health.
  • Lowers Risk of Recurrence: Consistent use reduces the recurrence of painful stone episodes, helping you maintain a normal daily routine without the sudden interruption of renal colic (severe pain caused when a kidney stone moves through the urinary tract).
Side effects of Duo-Cytra Oral Solution 200 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Directions for Use

  • Duo-Cytra 200Ml Solution can be taken with or without food, or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Duo-Cytra 200Ml Solution as a whole with a glass of water.
  • Do not chew, crush or break it.

How Duo-Cytra 200Ml Solution Works

It contains three active components that work together to balance your urine chemistry and stop stones from forming. Potassium citrate helps make the urine less acidic (more alkaline). This creates an environment that makes it harder for certain kidney stones, especially uric acid stones, to form. It also binds with calcium to form soluble complexes, reducing the amount of free calcium available to combine with oxalate or phosphate and form stones. Magnesium citrate provides magnesium, which can bind with oxalate in the urine. This reduces the amount of oxalate available to combine with calcium, helping lower the risk of calcium oxalate stone formation. Pyridoxine hydrochloride (Vitamin B6) helps reduce the body's production of oxalate in some people, particularly those with certain types of high oxalate levels (hyperoxaluria). Its benefit for preventing kidney stones in other people is still being studied.
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Alcohol

Caution

It is not known if alcohol interacts with Duo-Cytra 200Ml Solution. Please consult a doctor.

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Pregnancy

Caution

Please consult your doctor if you have any concerns; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Duo-Cytra 200Ml Solution; your doctor will decide whether breastfeeding mothers can take Duo-Cytra 200Ml Solution or not.

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Driving

Safe if prescribed

Duo-Cytra 200Ml Solution is unlikely to affect your ability to drive. However, you are advised to drive only if you are alert.

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Liver

Caution

Limited information is available regarding the usage of Duo-Cytra 200Ml Solution in patients with liver impairment. Please consult your doctor if you have liver problems before taking Duo-Cytra 200Ml Solution.

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Kidney

Unsafe

Duo-Cytra 200Ml Solution might cause soft tissue calcification and hyperkalaemia in patients with renal insufficiency. Please consult your doctor if you have kidney disease before taking Duo-Cytra 200Ml Solution.

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Children

Unsafe

The safety and effectiveness of Duo-Cytra 200Ml Solution in children have not been established.

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Heart

Caution

Please inform your doctor if you have heart problems before taking Duo-Cytra 200Ml Solution, as it may cause increased potassium levels, gastrointestinal discomfort, nausea, and changes in heart rhythm, which can be risky for individuals with cardiovascular conditions.

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Geriatrics

Caution

Please inform your doctor if you are geriatric before taking Duo-Cytra 200Ml Solution, as it may cause nausea, diarrhea, abdominal discomfort, electrolyte imbalance, and changes in heart rhythm, which can be more severe in older adults and increase the risk of dehydration, confusion, or cardiac complications.

What if I have taken an overdose of Duo-Cytra 200Ml Solution

If you suspect an overdose, seek emergency medical attention. Symptoms of an overdose may include severe muscle weakness, irregular heartbeats, chest pain, or confusion.

Diet & Lifestyle Advise

  • Increase fluid intake: Drink at least 2 to 3 liters of water daily to keep your urine diluted and reduce the risk of crystal formation.
  • Reduce dietary sodium: Lower your salt intake, as high sodium levels cause your kidneys to excrete more calcium, increasing the risk of stone formation.
  • Limit high-oxalate foods: Avoid or limit foods rich in oxalates, such as spinach, nuts, beets, and chocolate, if recommended by your doctor.
  • Moderate your protein intake: Limit excessive consumption of animal proteins, which can increase acid levels in your urine and promote stones.
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Have a query?

How Soon It Starts Working

The time required for Duo-Cytra 200Ml Solution to start to work: The time required for Duo-Cytra 200Ml Solution to show its action is unknown. The time for which the effects of Duo-Cytra 200Ml Solution last: The duration of action for Duo-Cytra 200Ml Solution is clinically unknown.

What if you forget to take Duo-Cytra 200Ml Solution

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

•Store at room temperature, ideally between 15°C and 30°C (59°F to 86°F), away from direct sunlight, excess heat, and moisture. •Do not store it in the bathroom.

Drug Warnings

  • Dilute Before Use: Always dilute the oral solution in water or juice as directed; drinking it undiluted can cause severe stomach irritation.
  • Check Medicine Before Use: Regularly check your medicine bottle for any changes in color or consistency; if you notice cloudiness or sediment in the liquid, do not take it and contact your pharmacist.
  • Regular Monitoring Is Important: Your doctor will arrange regular blood and urine tests to check your potassium levels, kidney function, and urine pH to make sure the medicine is working safely. For many people being treated for uric acid kidney stones, the goal is to keep the urine pH between 6.0 and 7.0. The frequency of these tests depends on your condition and is usually higher when treatment is first started or the dose is changed.
  • Check Before Taking Supplements: Do not start taking any new supplements, especially those containing potassium or calcium, without consulting your doctor first.

Drug-Drug Interactions

verifiedApollotooltip
  • Potassium-sparing diuretics: May increase the risk of dangerously high potassium levels.
  • ACE inhibitors and ARBs: Can raise potassium levels, so your doctor may monitor you more closely.
  • Aluminum-containing antacids: May increase aluminum absorption, especially if you have kidney problems.
  • Digoxin and other heart medicines: Changes in potassium levels may affect how these medicines work and increase the risk of abnormal heart rhythms.

Drug-Drug Interactions

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How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Taking Pyridoxine (vit b6), Magnesium citrate and Potassium citrate together with Promazine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Pyridoxine (vit b6), Magnesium citrate and Potassium citrate with Promazine is not recommended, as it may lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Taking Pyridoxine (vit b6), Magnesium citrate, and Potassium citrate(in tablet or capsule form) together with Clinidium bromide can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Co-administration of Pyridoxine (vit b6), Magnesium citrate and Potassium citrate with clidinium bromide is not recommended as it can lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience stomach pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), decreased hunger, black, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Taking Pyridoxine (vit b6), Magnesium citrate and Potassium citrate together with Procyclidine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Pyridoxine (vit b6), Magnesium citrate and Potassium citrate with procyclidine is not recommended, but it can be taken together if advised by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Taking Pyridoxine (vit b6), Magnesium citrate and Potassium citrate together with Mesoridazine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Co-administration of Pyridoxine (vit b6), Magnesium citrate and Potassium citrate with Mesoridazine is not recommended, as it may lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Taking Pyridoxine (vit b6), Magnesium citrate, and Potassium citrate(in tablet or capsule form) together with Biperiden can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Pyridoxine (vit b6), Magnesium citrate, and Potassium citrate(in tablet or capsule form) together with Biperiden is not recommended, as it may lead to an interaction but can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately.
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Taking Pyridoxine (vit b6), Magnesium citrate and Potassium citrate together with Darifenacin can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Pyridoxine (vit b6), Magnesium citrate and Potassium citrate together with Darifenacin is not recommended, as it may lead to an interaction but can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Taking Pyridoxine (vit b6), Magnesium citrate and Potassium citrate together with Scopolamine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Pyridoxine (vit b6), Magnesium citrate and Potassium citrate with Scopolamine is not recommended, as it may lead to an interaction but can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Taking Pyridoxine (vit b6), Magnesium citrate and Potassium citrate together with Phenindamine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Pyridoxine (vit b6), Magnesium citrate and Potassium citrate with Phenindamine is not recommended, as it may lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Taking Pyridoxine (vit b6), Magnesium citrate and Potassium citrate together with Orphenadrine (citrate) can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Pyridoxine (vit b6), Magnesium citrate and Potassium citrate together with Orphenadrine (citrate) is not recommended, as it may lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Duo-Cytra Oral Solution 200 ml:
Co-administration of Pyridoxine (vit b6), Magnesium citrate and Potassium citrate with Oxybutynin can increase the risk of developing stomach ulcers or bleeding.

How to manage the interaction:
Taking Pyridoxine (vit b6), Magnesium citrate and Potassium citrate with Oxybutynin is not recommended as it may lead to an interaction, it can be taken if prescribed by a doctor. Consult a doctor immediately if you experience severe stomach pain, bloating, lightheadedness, dizziness, vomiting (especially with blood), decreased hunger, or dark stools. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Potassium-rich foods and supplements: Avoid potassium supplements, potassium-containing salt substitutes, or large amounts of high-potassium foods unless your doctor advises otherwise.
  • High-sodium foods: Limiting salt intake may help reduce the risk of kidney stones and improve how well this medicine works.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[RENAL AND GENITOURINARY AGENT]

FAQs

Duo-Cytra 200Ml Solution is indicated for treating renal tubular acidosis and kidney stones. It also helps relieve the burning sensation during urination.
Duo-Cytra 200Ml Solution raises the urinary pH, potassium, magnesium and citric acid levels; this prevents the crystallisation of stone-forming salts.
Do not discontinue Duo-Cytra 200Ml Solution without consulting your doctor. To treat your condition effectually, continue taking Duo-Cytra 200Ml Solution for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Duo-Cytra 200Ml Solution.
The safety of Duo-Cytra 200Ml Solution during pregnancy is not fully established. Use it only if prescribed by your doctor. If you are pregnant, think you may be pregnant, or are planning to become pregnant, inform your doctor so they can carefully weigh the potential benefits and risks before recommending this medicine.
While taking Duo-Cytra 200Ml Solution, avoid foods high in potassium, like bananas, oranges, potatoes, spinach, and tomatoes. Too much potassium can be dangerous. Also, limit foods high in oxalates, like nuts, chocolate, and tea, to help prevent kidney stones. It's best to consult a dietitian for personalized dietary advice and suggestions.
Before starting Duo-Cytra 200Ml Solution, tell your doctor if you are allergic to any of its ingredients or if you have high potassium levels (hyperkalemia), chronic renal failure, renal insufficiency, uncontrolled diabetes, adrenal insufficiency, acute dehydration, oesophageal compression, delayed gastric emptying, intestinal obstruction, peptic ulcers, or an active urinary tract infection. Also inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. This medicine is generally not recommended for children. Your doctor will decide whether it is safe and appropriate for you.
While taking Duo-Cytra 200Ml Solution, avoid certain medications to prevent interactions. These include antibiotics like tetracyclines and fluoroquinolones, bisphosphonates like Fosamax and Actonel, ACE inhibitors like Lisinopril, diuretics like furosemide, and proton pump inhibitors like omeprazole. Please note that this is not an exhaustive list. Inform your doctor about all medications, including over-the-counter drugs and supplements, to ensure safe usage. Your doctor will provide complete guidance.
The common side effects of Duo-Cytra 200Ml Solution include abdominal discomfort, diarrhoea, nausea, and vomiting. These are usually mild and resolve on their own as your body adjusts to the medicine. Drink plenty of fluids and eat non-spicy food if you develop diarrhoea. If the diarrhoea is severe, persistent, or accompanied by blood in the stools (tarry stools), contact your doctor immediately. Do not take anti-diarrhoeal medicines without consulting your doctor.
No, it is best to take after meals or with food to help prevent stomach upset and irritation. Talk to your doctor or pharmacist for personalized advice.
You should drink plenty of fluids, typically aiming for 2 to 3 liters of water daily, to help the medicine work effectively and prevent kidney stones. Talk to your doctor about your specific fluid needs.
If you notice any cloudiness, color change, or particles in your liquid, do not take it. Return it to your pharmacist for a safe replacement.
Do not take potassium supplements or salt substitutes containing potassium while using this medicine, as this can cause dangerously high potassium levels in your blood. Talk to your doctor first.
It is best to limit or avoid alcohol while taking it , as alcohol can dehydrate you and increase the risk of kidney stone formation. Talk to your doctor.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA
Other Info - DUO0166
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