Duloctus M 20mg/750mcg Tablet belongs to the class of medications called ‘anticonvulsants’ used to treat neuropathic pain. Neuropathic pain is a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system's malfunctioning. It is mainly seen in patients who have suffered a trauma or nerve injury, diabetes, vitamin deficiencies, cancer, multiple sclerosis (a disease of the brain and spinal cord), shingles (a viral infection), and HIV.

Duloctus M 20mg/750mcg Tablet is a combination of two medicines: Duloxetine and Methylcobalamin. Duloxetine is a selective serotonin reuptake inhibitor (SSRI) that works by increasing the levels of a chemical messenger (like serotonin and noradrenaline) in the brain required to regulate pain that travels through damaged nerves. On the other hand, Methylcobalamin is a form of vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (a protective layer of nerve cells). 

Take this medicine as prescribed by your doctor. Duloctus M 20mg/750mcg Tablet may cause side effects such as drowsiness, nausea, constipation, headache, dry mouth, increased sweating, anorexia (loss of appetite), and a hot sensation (burning pain). Inform your doctor if any of these side effects persist.

Do not take Duloctus M 20mg/750mcg Tablet if you are allergic to Duloxetine, Methylcobalamin, or any of its contents. Before taking Duloctus M 20mg/750mcg Tablet, inform your doctor if you have liver or kidney disease, seizures (fits), mania, bipolar disorder, glaucoma (an eye condition), bleeding disorders, or at risk of hyponatremia (low sodium levels, especially in patients taking diuretics or water pills). It is not recommended for use in children and young adults as it increases the risk of suicidal tendencies. Inform your doctor if you are pregnant or breastfeeding before using Duloctus M 20mg/750mcg Tablet.

• Take Duloctus M 20mg/750mcg Tablet with or without food or as advised by a doctor. • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety. • Swallow the medicine as a whole with glass of water. • Do not crush, break, or chew it.

Duloctus M 20mg/750mcg Tablet is a combination of two medicines: Duloxetine and Methylcobalamin. Duloxetine is a selective serotonin reuptake inhibitor (SSRI) that increases serotonin and noradrenaline levels in the brain, which are required for regulating pain through the damaged nerves. Methylcobalamin is a form of vitamin B12 that helps in rejuvenating and protecting damaged nerve cells by producing a substance called myelin (a protective layer of nerve cells). Together, Duloctus M 20mg/750mcg Tablet effectively treats neuropathic pain and improves nerve conduction, promoting proper nerve signal functioning throughout the body.

Before taking Duloctus M 20mg/750mcg Tablet, inform your doctor if you have taken any antidepressants within the last 14 days or any medications used to treat infections. Please consult your doctor before stopping the medicine, as it may cause withdrawal symptoms such as dizziness, tingling sensations, sleep disturbances, restlessness, nausea or vomiting, headache, or excessive sweating. Therefore, do not abruptly stop taking your medicine, even if your symptoms improve. It may increase suicidal thoughts, so it is advised to use caution in patients with mania, bipolar disorder or depression. Prolonged use of Duloctus M 20mg/750mcg Tablet may decrease sodium level, affect blood pressure, and blood sugar level, so regular medical check-ups are required. Duloctus M 20mg/750mcg Tablet may increase your bleeding risk, and worsen your glaucoma condition. Hence, if you experience any eye problems or bleeding problems, consult a doctor.