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Draminate 50 mg Tablet is used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness. It is also used to manage nausea and vomiting associated with radiation sickness, surgery, and drug-induced Meniere’s disease (a condition that causes a spinning sensation and inner ear problems). Draminate 50 mg Tablet contains Dimenhydrinate, which works by blocking histamine and muscarinic receptors in the brain that trigger these symptoms. Common side effects may include dry mouth, blurred vision, drowsiness, dizziness, headache, fatigue, disorientation, tinnitus, palpitations, and low blood pressure. Before taking this medicine, inform your doctor if you are allergic to any of its components, are pregnant or breastfeeding, and about any other medications you are taking or pre-existing medical conditions.

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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

DIMENHYDRINATE-50MG

Manufacturer/Marketer :

RPG Life Sciences Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Draminate 50 mg Tablet

Draminate 50 mg Tablet is an oral tablet used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness. It helps settle the inner ear and brain signals that trigger these uncomfortable symptoms during travel. Draminate 50 mg Tablet is commonly used by people who experience discomfort while traveling by car, plane, boat, or train.

For the best results, you should take Draminate 50 mg Tablet consistently before you start traveling or as directed by your healthcare provider. You can take Draminate 50 mg Tablet with or without food, though taking it with food or a glass of milk may help prevent an upset stomach. Staying well-hydrated and focusing your eyes on the horizon can also help improve your travel comfort.

While taking Draminate 50 mg Tablet , you may experience mild side effects like drowsiness, dry mouth, or blurred vision. These effects are usually temporary and go away as Draminate 50 mg Tablet wears off. However, you must contact your doctor immediately if you experience serious symptoms such as a fast or irregular heartbeat, severe dizziness, or signs of an allergic reaction.

Talk to your doctor before taking Draminate 50 mg Tablet if you have certain health conditions. Do not take this if you have glaucoma, difficulty urinating due to an enlarged prostate, or chronic breathing problems like asthma or emphysema. Your doctor can help determine if Draminate 50 mg Tablet is safe for your specific health history.

Draminate 50 mg Tablet can interact with alcohol, sedatives, and other medicines that cause sleepiness, making you feel extremely drowsy. If you are pregnant, breastfeeding, or an older adult, consult your doctor or pharmacist before using Draminate 50 mg Tablet to ensure it is safe for you.

Uses of Draminate 50 mg Tablet

Draminate 50 mg Tablet is used in the treatment of motion sickness. The detailed uses of Draminate 50 mg Tablet are as follows:

  • Motion sickness: Draminate 50 mg Tablet prevents and relieves nausea, vomiting, and dizziness caused by the motion of travel in cars, boats, planes, or trains.
  • Vertigo and dizziness: Draminate 50 mg Tablet helps manage spinning sensations and balance issues related to inner ear problems.
     

Key Benefits

Draminate 50 mg Tablet helps prevent and relieve motion sickness by reducing the signals that trigger nausea, vomiting, and dizziness. It provides effective symptom control, helping make travel and daily activities more comfortable.

Benefits may include:

  • Helps relieve nausea and vomiting caused by motion sickness.
  • Reduces dizziness and the uncomfortable feeling of being unsteady during travel.
  • Helps prevent motion sickness when taken before travelling as directed.
  • Makes journeys by car, bus, train, plane, or boat more comfortable.
  • Supports participation in travel and daily activities without frequent interruptions from motion sickness.
  • Improves overall comfort and quality of life during travel when used as prescribed.

Directions for Use

  • Draminate 50 mg Tablet can be taken with or without food.
  • Take the first dose 30 to 60 minutes before travelling or starting any motion-related activity if using it for motion sickness.
  • It is typically administered every 4-6 hours as needed, or as directed by your doctor.
  • Chew the tablet thoroughly before swallowing.
  • Do not crush, break, or swallow it as a whole.

How Draminate 50 mg Tablet Works

Draminate 50 mg Tablet works by blocking certain natural substances in the body, specifically histamine and acetylcholine. Inside your inner ear, there are balance centers that detect movement. When you travel, mismatching signals between your eyes and your inner ear can confuse your brain, leading to motion sickness. By blocking these chemical messengers in the brain and inner ear, Draminate 50 mg Tablet reduces the stimulation that triggers nausea, vomiting, and dizziness. This helps keep your nervous system calm and balanced even during bumpy or winding journeys.
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Alcohol

Caution

Avoid alcohol consumption while taking Draminate 50 mg Tablet , as it may cause increased drowsiness.

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Pregnancy

Caution

Draminate 50 mg Tablet is a pregnancy category B drug. Please consult your doctor if you are pregnant or planning to become pregnant. Your doctor will weigh the benefits and any potential risks before prescribing Draminate 50 mg Tablet .

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Breast Feeding

Caution

It is not known whether Draminate 50 mg Tablet passes into breast milk or harms a nursing baby. Please consult your doctor if you are breastfeeding.

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Driving

Caution

Draminate 50 mg Tablet may cause drowsiness and dizziness. So, avoid driving or operating heavy machinery while using Draminate 50 mg Tablet .

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Liver

Caution

Draminate 50 mg Tablet should be used with caution in patients with liver diseases. Please consult your doctor before taking Draminate 50 mg Tablet . Your doctor will weigh the benefits and any potential risks before prescribing Draminate 50 mg Tablet .

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Kidney

Caution

Draminate 50 mg Tablet should be used with caution in patients with kidney diseases. Please consult your doctor before taking Draminate 50 mg Tablet . Your doctor will weigh the benefits and any potential risks before prescribing Draminate 50 mg Tablet .

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Children

Caution

Draminate 50 mg Tablet is not recommended for use in children below 2 years of age. For children above 2 years of age, dose adjustments may be necessary if prescribed.

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Heart

Consult your doctor

Inform your doctor if you have heart disease before using Draminate 50 mg Tablet . Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Draminate 50 mg Tablet should be given to the elderly only when prescribed by a doctor. If you have any concerns about using Draminate 50 mg Tablet for geriatrics, please consult a doctor.

What if I have taken an overdose of Draminate 50 mg Tablet

If you suspect an overdose, seek immediate medical attention or call a poison control center. Symptoms of an overdose may include extreme drowsiness, dilated pupils, fever, flushing, restlessness, or seizures.

Diet & Lifestyle Advise

  • Choose your seat wisely: When traveling, sit in the area with the least motion, such as the front seat of a car, over the wing on an airplane, or on the middle deck of a boat.
  • Keep your eyes on the horizon: Look at a fixed point in the distance rather than reading, looking at screens, or watching moving objects outside.
  • Avoid heavy meals before travel: Eat light, bland snacks like crackers before and during your journey. Avoid greasy, spicy, or heavy foods that can upset your stomach.
  • Ensure good ventilation: Direct fresh air or air conditioning toward your face while traveling to help reduce feelings of nausea.
  • Stay hydrated: Drink small sips of water or clear fluids, and avoid beverages containing caffeine or alcohol before and during your trip.
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How Soon It Starts Working

The time required for Draminate 50 mg Tablet to start to work: Draminate 50 mg Tablet ideally shows its action within 15 to 30 minutes after administration. The time for which the effects of Draminate 50 mg Tablet last: The effect of Draminate 50 mg Tablet lasts for 3 to 6 hours.

What if you forget to take Draminate 50 mg Tablet

If you are taking Draminate 50 mg Tablet on a regular schedule and miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Draminate 50 mg Tablet at controlled room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Avoid driving or operating machinery: Draminate 50 mg Tablet can cause significant drowsiness and slow your reaction times. Do not drive, ride a bicycle, or use dangerous tools until you know how Draminate 50 mg Tablet affects you.
  • Do not combine with alcohol: Drinking alcohol while taking Draminate 50 mg Tablet can severely increase drowsiness and dizziness, which can be dangerous.
  • Use caution in hot weather: Draminate 50 mg Tablet can decrease sweating, making you more prone to overheating. Avoid strenuous activity in hot environments and drink plenty of fluids.
  • Monitor older adults closely: Elderly individuals may be more sensitive to the side effects of Draminate 50 mg Tablet , especially drowsiness, confusion, dizziness, and difficulty urinating, which can increase the risk of falls.
  • Check other allergy or cold medicines: Many over-the-counter cough, cold, or allergy remedies also contain antihistamines. Read labels carefully to avoid accidentally taking too much of this type of medicine.

Drug-Drug Interactions

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  • Central nervous system depressants (e.g., sleeping pills, sedatives, anxiety medicines): Taking these medicines alongside Draminate 50 mg Tablet may cause excessive drowsiness, dizziness, slowed breathing, and reduced alertness.
  • Monoamine oxidase inhibitors (MAOIs) (e.g., phenelzine, tranylcypromine): Using these medicines with Draminate 50 mg Tablet may increase anticholinergic side effects such as dry mouth, blurred vision, fast heartbeat, and difficulty passing urine.
  • Tricyclic antidepressants (e.g., amitriptyline, imipramine): Taking these medicines alongside Draminate 50 mg Tablet may increase drowsiness and anticholinergic side effects such as dry mouth, blurred vision, constipation, and difficulty passing urine.
  • Other antihistamines (e.g., cetirizine, chlorpheniramine): Combining these medicines with Draminate 50 mg Tablet may increase drowsiness and drying effects.
DimenhydrinatePotassium citrate
Critical

Drug-Drug Interactions

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DimenhydrinatePotassium citrate
Critical
How does the drug interact with Draminate 50 mg Tablet:
Co-administration of Draminate 50 mg Tablet and Potassium citrate can increase the risk of developing stomach inflammation.

How to manage the interaction:
Taking Draminate 50 mg Tablet with Potassium citrate is generally avoided, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, sudden lightheadedness, vomiting (especially with blood), or tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Draminate 50 mg Tablet:
Co-administration of Draminate 50 mg Tablet and Potassium chloride can increase the risk of stomach inflammation.

How to manage the interaction:
Co-administration of Draminate 50 mg Tablet with Potassium chloride is generally not recommended, as it can lead to an interaction, it can be taken when a doctor has prescribed it. However, if you experience severe stomach pain, sudden dizziness, vomiting (especially with blood), or dark stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
DimenhydrinateSodium oxybate
Severe
How does the drug interact with Draminate 50 mg Tablet:
Using Draminate 50 mg Tablet and sodium oxybate together can increase the risk of side effects.

How to manage the interaction:
Co-administration of Draminate 50 mg Tablet and sodium oxybate can lead to an interaction, it can be taken if your doctor advises. however contact your doctor if you experience dizziness, confusion, difficulty concentrating, breathing difficulty, or palpitations. Do not stop using any medications without a doctor's advice.
How does the drug interact with Draminate 50 mg Tablet:
The combined use of ketamine and Draminate 50 mg Tablet can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of ketamine and Draminate 50 mg Tablet can lead to an interaction, but it can be taken if advised by your doctor. however contact your doctor if you experience any side effects such as dizziness, confusion, difficulty concentrating, or shortness of breath. Do not stop using any medications without a doctor's advice.
How does the drug interact with Draminate 50 mg Tablet:
Coadministration of Draminate 50 mg Tablet with topiramate can increase the risk of topiramate side effects.

How to manage the interaction:
Taking Draminate 50 mg Tablet with topiramate is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience decreased sweating, fever, dizziness, or shortness of breath, contact your doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Draminate 50 mg Tablet:
Coadministration of Draminate 50 mg Tablet with Zonisamide can increase the risk or severity of Zonisamide side effects.

How to manage the interaction:
Taking Draminate 50 mg Tablet with Zonisamide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience shortness of breath, palpitations, fever, or excessive sweating, contact a doctor. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
DimenhydrinateEsketamine
Severe
How does the drug interact with Draminate 50 mg Tablet:
Co-administration of Esketamine and Draminate 50 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Co-administration of esketamine and Draminate 50 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. Consult a doctor if you experience drowsiness, confusion, shortness of breath, or palpitations. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid drinking alcohol while taking Draminate 50 mg Tablet , as it may greatly increase drowsiness, dizziness, and problems with coordination.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIHISTAMINE]

FAQs

Draminate 50 mg Tablet is used to prevent and treat nausea (feeling sick), vomiting (being sick), and dizziness caused by motion sickness. Besides this, it is also used to treat nausea and vomiting associated with radiation sickness, surgery, and drug-induced Meniere disease (feelings of spinning and inner ear problems).
Draminate 50 mg Tablet contains Dimenhydrinate, which acts as both an antihistamine and an anticholinergic. It works by blocking histamine (H₁) receptors and muscarinic (M₁) receptors in the brain areas responsible for balance and nausea. This action helps reduce signals that lead to motion sickness, providing relief from nausea, vomiting, and dizziness.
Yes, the use of Draminate 50 mg Tablet can cause dry mouth. If you feel excessively thirsty, increase fluid intake and avoid spicy and salty food.
Draminate 50 mg Tablet is usually recommended for short-term use. Do not take longer than prescribed unless advised by your doctor.
Draminate 50 mg Tablet is generally safe if used as per the prescribed dose and duration. It's important to follow your doctor's instructions.
Draminate 50 mg Tablet is generally not addictive when used as prescribed by your doctor. However, it’s important to follow your doctor's instructions to avoid any potential misuse.
No, using Draminate 50 mg Tablet together with Cymbalta (contains Duloxetine) may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. However, consult your doctor if you have any concerns.
Yes, Draminate 50 mg Tablet can cause drowsiness or tiredness as side effects. It's essential to exercise caution when taking this medication, particularly if you need to drive, operate machinery, or perform tasks that require mental alertness. If you experience excessive drowsiness or tiredness, it's best to avoid such activities.
No, Draminate 50 mg Tablet does not contain aspirin. The active ingredient in Draminate 50 mg Tablet is dimenhydrinate, which is an antihistamine used to treat motion sickness, nausea, and vomiting.
The side effects of Draminate 50 mg Tablet are dry mouth, blurred vision, drowsiness, dizziness, headache, tiredness, disorientation, tinnitus, palpitation, and low blood pressure (hypotension). Most of these side effects do not require medical attention and resolve gradually over time. However, seek medical attention immediately if these side effects persist or worsen.
To prevent motion sickness, you should take Draminate 50 mg Tablet 30 to 60 minutes before you start your trip. This gives Draminate 50 mg Tablet enough time to absorb and begin working. If you need further advice on timing, talk to your doctor.
Children can take certain strengths of Draminate 50 mg Tablet , but the dose must be carefully calculated based on their age. Never give Draminate 50 mg Tablet to children under 2 years old unless specifically instructed by a pediatrician. Inform your doctor before giving Draminate 50 mg Tablet to a child.
You should consult your healthcare provider before taking Draminate 50 mg Tablet during pregnancy. They will help you weigh the benefits against any potential risks to your baby. If you have questions about morning sickness treatments, consult your doctor.
Many over-the-counter allergy and cold medicines contain similar ingredients that can cause severe drowsiness or dry mouth if taken together. Always check the active ingredients on packaging or ask a professional. Inform your doctor before combining medications.
While caffeine does not have a direct dangerous interaction with Draminate 50 mg Tablet , it may temporarily counteract some of the drowsiness. However, caffeine can also worsen anxiety or stomach upset in some people. Talk to your doctor if you are unsure about your diet.
If your motion sickness or dizziness does not improve after taking Draminate 50 mg Tablet , do not take extra doses beyond what is recommended. Persistent nausea may be a sign of another underlying condition. Consult your doctor to explore alternative treatment options.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA
Other Info - DRA0005
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