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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Dostimine 60 mg Tablet 10's is used to treat myasthenia gravis (muscle weakness). Besides this, it also treats paralytic ileus (a rare form of constipation), postoperative urinary retention, and prophylaxis to military exposure to any nerve poisoning gas. It contains Pyridostigmine, which works by stopping the excessive cholinesterase activity (an enzyme required for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, helps in proper muscle functioning and prevents muscle weakness. In some cases, you may experience common side effects, such as stomach pain, nausea, vomiting, diarrhoea, sweating, cough with mucus, rash, muscle cramps, and blurred vision. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

PYRIDOSTIGMINE-60MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Dostimine 60 mg Tablet 10's

Dostimine 60 mg Tablet 10's is used to treat myasthenia gravis (muscle weakness). Besides this, Dostimine 60 mg Tablet 10's also treats paralytic ileus (a rare form of constipation), postoperative urinary retention, and prophylaxis to military exposure to any nerve poisoning gas. Myasthenia gravis is a long-term neuromuscular disease that leads to musculoskeletal weakness caused by excess activity of a protein (cholinesterase protein).

Dostimine 60 mg Tablet 10's contains ‘Pyridostigmine’, which works by stopping the excessive cholinesterase activity (an enzyme required for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, Dostimine 60 mg Tablet 10's helps in proper muscle functioning and prevents muscle weakness. 

Take Dostimine 60 mg Tablet 10's 30-60 minutes before food. Swallow Dostimine 60 mg Tablet 10's as a whole; do not crush or chew the tablet. You are advised to take Dostimine 60 mg Tablet 10's as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as stomach pain, nausea, vomiting, diarrhoea, sweating, cough with mucus, rash, muscle cramps, and blurred vision. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor before taking Dostimine 60 mg Tablet 10's if you have asthma, high blood pressure, glaucoma, breathing problems, coronary obstruction, stomach ulcer, epilepsy, Parkinson’s disease, or kidney problems. Consult your doctor before taking Dostimine 60 mg Tablet 10's if you are pregnant before taking Dostimine 60 mg Tablet 10's if you are pregnant or breastfeeding. Dostimine 60 mg Tablet 10's may cause dizziness and vision problems, so drive or operate machinery only if you are alert. Avoid consuming alcohol while taking Dostimine 60 mg Tablet 10's as it may cause increased dizziness. Dostimine 60 mg Tablet 10's can be given to children if prescribed by the doctor; the dose depends upon the child’s age. Keep your doctor informed about your health condition and medicines you are taking to rule out unpleasant side effects.

Uses of Dostimine 60 mg Tablet 10's

Treatment of Myasthenia gravis (muscle weakness)

Directions for Use

• Dostimine 60 mg Tablet 10's can be taken 30-60 minutes before food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Swallow Dostimine 60 mg Tablet 10's as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

Dostimine 60 mg Tablet 10's belongs to the group of medicines called cholinesterase inhibitors used to treat myasthenia gravis (muscle weakness). Dostimine 60 mg Tablet 10's works by stopping the excessive activity of cholinesterase, thus helping the muscles to work properly. Additionally, Dostimine 60 mg Tablet 10's is also used to treat paralytic ileus (a rare form of constipation), postoperative urinary retention, and prophylaxis to soman nerve agent poisoning. Dostimine 60 mg Tablet 10's affects the chemicals in the body which are involved in communication between nerve impulses and muscle movements. Thereby, Dostimine 60 mg Tablet 10's helps in treating myasthenia gravis.

How Dostimine 60 mg Tablet 10's Works

Dostimine 60 mg Tablet 10's contains pyridostigmine, which works by stopping the excessive cholinesterase activity (an enzyme required for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, Dostimine 60 mg Tablet 10's helps in proper muscle functioning and prevents muscle weakness.

Storage

Keep Dostimine 60 mg Tablet 10's out of reach and sight of children.

What if I have taken an overdose of Dostimine 60 mg Tablet 10's

Do not take more than the prescribed dose of Dostimine 60 mg Tablet 10's as it may cause overdose. The symptoms of overdose include stomach cramps, sweating, nausea, vomiting, diarrhea, blurred vision, drooling, and weak or shallow breathing. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Dostimine 60 mg Tablet 10's if you are allergic to any of its contents; if you are constipated or cannot urinate unless prescribed by the doctor. Inform your doctor before taking Dostimine 60 mg Tablet 10's if you have asthma, high blood pressure, glaucoma, breathing problems, coronary obstruction, stomach ulcer, epilepsy, Parkinson’s disease, kidney problems, vagotonia (overactive vagus nerves), overactive thyroid; if you have had surgery to remove thymus gland or if you due to have any surgery. Consult your doctor before taking Dostimine 60 mg Tablet 10's if you are pregnant before taking Dostimine 60 mg Tablet 10's if you are pregnant or breastfeeding. Dostimine 60 mg Tablet 10's may cause dizziness and vision problems; so, drive or operate machinery only if you are alert. Avoid consuming alcohol while taking Dostimine 60 mg Tablet 10's as it may cause increased dizziness. 

Diet & Lifestyle Advise

  • Maintain a healthy weight. Include vegetables, fruits and grains in your diet.
  • Diet low in fat, saturated fat and cholesterol would be helpful.
  • Use salt and sugars in moderation.
  • Avoid consumption of alcohol.
  • Avoid processed and fried foods.
  • Try eating soft, mashed, or pureed foods as they are easy to swallow.
  • Avoid dry, chunky and chewy foods.
  • Regularly sip water during meals and snacks as it helps to moisten and soften the food. 
  • Add thickening agents to liquid foods as liquid foods may get into the lungs and cause choking.
  • Be careful while swallowing foods and liquids.

Habit Forming

No

Therapeutic Class

MUSCLE STIMULANTS AND CHOLINESTERASE INHIBITORS
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Alcohol

Unsafe

Avoid consuming alcohol while taking Dostimine 60 mg Tablet 10's as it may cause increased dizziness.

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Pregnancy

Caution

Dostimine 60 mg Tablet 10's belongs to the pregnancy category C. Please consult your doctor before taking Dostimine 60 mg Tablet 10's if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Small amounts of Dostimine 60 mg Tablet 10's may pass into breastmilk. Please consult your doctor before taking Dostimine 60 mg Tablet 10's if you are breastfeeding.

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Driving

Unsafe

Dostimine 60 mg Tablet 10's may cause dizziness and vision problems. So, drive only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor before taking Dostimine 60 mg Tablet 10's if you have liver impairment/liver disease before taking Dostimine 60 mg Tablet 10's.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Dostimine 60 mg Tablet 10's.

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Children

Unsafe

Not recommended for use in anyone less than 18 years of age

Have a query?

FAQs

Dostimine 60 mg Tablet 10's is used to treat myasthenia gravis (muscle weakness). Besides this, it also treats paralytic ileus (a rare form of constipation), postoperative urinary retention, and prophylaxis to military exposure to any nerve-poisoning gas.

Dostimine 60 mg Tablet 10's works by stopping the excessive cholinesterase activity (an enzyme necessary for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, Dostimine 60 mg Tablet 10's helps in proper muscle functioning and prevents muscle weakness.

Dostimine 60 mg Tablet 10's is used as prophylaxis against the lethal effects of soman nerve agent poisoning especially by military. It is intended to be used in conjunction with atropine and pralidoxime therapy and protective garments and gas-mask.

Do not stop taking Dostimine 60 mg Tablet 10's on your own. To treat your condition effectually continue taking Dostimine 60 mg Tablet 10's for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Dostimine 60 mg Tablet 10's.

Caution is needed in patients with asthma, breathing difficulty, wheezing and chronic cough as Dostimine 60 mg Tablet 10's may worsen the condition. Please consult your doctor before taking Dostimine 60 mg Tablet 10's if you have asthma or any breathing problems.

Talk to your doctor before taking Dostimine 60 mg Tablet 10's if you have hypertension (high blood pressure) as it may cause insignificant changes such as elevated blood pressure.

Anticholinergic drugs are often used in the treatment of glaucoma. Dostimine 60 mg Tablet 10's is a cholinergic inhibitor, and its use in patients with glaucoma may cause additive effects which could lead to night vision problems. Please consult your doctor before taking Dostimine 60 mg Tablet 10's if you have glaucoma.

Dostimine 60 mg Tablet 10's may cause side effects such as nausea, vomiting, diarrhoea, stomach pain, muscle cramps, blurred vision, rash and increased salivation. If these side effects persist or worsen, please consult your doctor.

Dostimine 60 mg Tablet 10's does not cause high blood pressure. In fact, intake of high dose of Dostimine 60 mg Tablet 10's can cause low blood pressure.

No, Dostimine 60 mg Tablet 10's should not be crushed or chewed. It should be taken as a whole with water.

Dostimine 60 mg Tablet 10's does not cause increase in heartbeats. On the other hand, it can be used in the treatment of increase in heartbeats in postural orthostatic tachycardia syndrome (POTS) where there is an abnormal increase in the heartbeats while standing from a lying position.

Dostimine 60 mg Tablet 10's should not be cut in half unless your doctor tells you to take a half tablet and it has a score mark on it. It should not be chewed or crushed before taking.

Dostimine 60 mg Tablet 10's does not cure myasthenia gravis but relieves the symptoms of it by reducing and improving muscle weakness. The duration for which you must take Dostimine 60 mg Tablet 10's will depend on your needs. Do not stop taking Dostimine 60 mg Tablet 10's until and unless advised by your doctor, even if you start feeling better.

A very small amount of Dostimine 60 mg Tablet 10's may pass into breast milk, which may or may not affect your baby. Please take your doctor’s advice before taking Dostimine 60 mg Tablet 10's if you are breastfeeding.

No, do not take Dostimine 60 mg Tablet 10's for constipation. It is used only when constipation occurs due to intestinal paralysis and strictly on prescription by the doctor.

Dostimine 60 mg Tablet 10's should not be taken by patients who are allergic to it, who have constipation or difficulty urinating, unless the doctor has advised to use this medicine.

If you have accidentally taken more than the required dose, seek medical help immediately. An overdose of Dostimine 60 mg Tablet 10's may cause nausea, vomiting, stomach pain, diarrhea, salivation, excessive sweating, blurred vision, difficulty in breathing, excessive weakness, and even paralysis.

No, Dostimine 60 mg Tablet 10's is not a steroid. It belongs to the group of medicines called anticholinesterases.

No, there is no proof that Dostimine 60 mg Tablet 10's has abuse potential.

No, Dostimine 60 mg Tablet 10's does not cause weight gain. However, if you gain weight, it may be due to inactivity related to muscle weakness in myasthenia gravis.

Yes, Dostimine 60 mg Tablet 10's is safe if used as advised by the doctor. Do not exceed the recommended dose.

Dostimine 60 mg Tablet 10's may cause blurred vision. Thus, you should avoid driving until you know how Dostimine 60 mg Tablet 10's affects you.

Country of origin

India

Manufacturer/Marketer address

4-6, Bora Bazar St, Borabazar Precinct, Ballard Estate, Fort, Mumbai, Maharashtra 400001
Other Info - DOS0074

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