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compositionComposition:PYRIDOSTIGMINE-60MG
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Prescription Medicine
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Dostimine 60 mg Tablet 10's is used to treat myasthenia gravis (muscle weakness). Besides this, it also treats paralytic ileus (a rare form of constipation), postoperative urinary retention, and prophylaxis to military exposure to any nerve poisoning gas. It contains Pyridostigmine, which works by stopping the excessive cholinesterase activity (an enzyme required for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, helps in proper muscle functioning and prevents muscle weakness. In some cases, you may experience common side effects, such as stomach pain, nausea, vomiting, diarrhoea, sweating, cough with mucus, rash, muscle cramps, and blurred vision. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Mrs. Veda Maddala , M Pharmacy
Reviewed By Dr. Balem Snigdha Reddy , MD, MBBS
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More about the Product

Composition :

PYRIDOSTIGMINE-60MG

Manufacturer/Marketer :

Prevego Healthcare & Research Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Dostimine 60 mg Tablet 10's

Dostimine 60 mg Tablet 10's is a prescription medicine primarily used to treat myasthenia gravis, a chronic autoimmune condition that causes muscle weakness and fatigue. Living with myasthenia gravis can be challenging, but with the right treatment plan many people are able to manage their symptoms and carry out their daily activities. Dostimine 60 mg Tablet 10's works by improving communication between your nerves and muscles, helping restore muscle strength needed for activities such as chewing, swallowing, and breathing.

For the best results, you must take Dostimine 60 mg Tablet 10's consistently at the exact times prescribed by your doctor, especially if you need it to help with chewing or swallowing. It is generally recommended to take this medicine with food or a small snack to reduce stomach upset. Planning your meals around your dosing schedule can make eating much easier and safer.

While taking Dostimine 60 mg Tablet 10's, you may experience mild side effects such as increased salivation, sweating, mild stomach cramps, or nausea. However, if you notice serious symptoms like extreme muscle weakness, difficulty breathing, or a very slow heart rate, contact your doctor immediately.

Do not take this if you have a physical blockage in your intestines or urinary tract. Before starting Dostimine 60 mg Tablet 10's, let your doctor know if you have asthma, chronic obstructive pulmonary disease (COPD), or any heart rhythm problems, as this medicine can worsen these conditions.

Avoid drinking alcohol while taking this medicine, as it can worsen stomach side effects and increase drowsiness. Talk to your doctor if you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, as your dose may need careful monitoring.

Uses of Dostimine 60 mg Tablet 10's

Dostimine 60 mg Tablet 10's is used to manage the following conditions: 

  • Myasthenia gravis: Dostimine 60 mg Tablet 10's helps improve muscle strength and reduce muscle fatigue in people with this chronic autoimmune disorder.
  • Nerve gas exposure protection: In specific military or government-authorised situations, Dostimine 60 mg Tablet 10's may be used as a preventive measure before potential exposure to certain nerve agents. This is a specialised use and is not a routine civilian indication or self-medication option. 

Key Benefits

Dostimine 60 mg Tablet 10's provides real-world relief by helping you regain control over your muscles. The primary benefits include:

  • Improved Muscle Control: It significantly increases muscle strength, allowing you to perform daily tasks like walking, lifting, and speaking more easily.
  • Easier Eating and Swallowing: By strengthening the muscles in the throat and mouth, Dostimine 60 mg Tablet 10's helps you chew and swallow food safely, reducing the risk of choking.
  • Restored Energy for Daily Activities: It helps prevent the rapid muscle fatigue that typically worsens throughout the day, enabling you to maintain physical activity longer.

Directions for Use

Follow these instructions to take Dostimine 60 mg Tablet 10's safely and effectively: 

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet unless your doctor specifically instructs you to do so. Extended-release tablets must always be swallowed whole, as they are designed to release the medicine slowly over several hours and are often prescribed to provide longer-lasting symptom control, including overnight.
  • Take this medicine at the exact times your doctor prescribes. For example, if you have trouble swallowing during meals, taking your dose 30 to 45 minutes before eating can make a significant difference.
  • Always follow your doctor's exact instructions regarding how and when to take this medicine, and never adjust your timing or dose on your own.

How Dostimine 60 mg Tablet 10's Works

Dostimine 60 mg Tablet 10's contains pyridostigmine, which works by stopping the excessive cholinesterase activity (an enzyme required for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, Dostimine 60 mg Tablet 10's helps in proper muscle functioning and prevents muscle weakness.
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Alcohol

Unsafe

Avoid consuming alcohol while taking Dostimine 60 mg Tablet 10's as it may cause increased dizziness.

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Pregnancy

Consult your doctor

Dostimine 60 mg Tablet 10's belongs to the pregnancy category C. Please consult your doctor before taking Dostimine 60 mg Tablet 10's if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

Small amounts of Dostimine 60 mg Tablet 10's may pass into breastmilk. Please consult your doctor before taking Dostimine 60 mg Tablet 10's if you are breastfeeding.

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Driving

Unsafe

Dostimine 60 mg Tablet 10's may cause dizziness and vision problems. So, drive only if you are alert.

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Liver

Consult your doctor

Dose adjustment may be needed. Please consult your doctor before taking Dostimine 60 mg Tablet 10's if you have liver disease before taking Dostimine 60 mg Tablet 10's.

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Kidney

Consult your doctor

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Dostimine 60 mg Tablet 10's.

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Children

Unsafe

Not recommended for use in anyone less than 18 years of age

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Heart

Consult your doctor

Consult your doctor before taking Dostimine 60 mg Tablet 10's if you have heart problems or any concerns regarding this.

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Geriatrics

Caution

Careful monitoring and proper dose adjustments are needed while taking Dostimine 60 mg Tablet 10's in elderly patients.

What if I have taken an overdose of Dostimine 60 mg Tablet 10's

In case of an accidental overdose, seek immediate medical attention or call emergency services. Symptoms may include severe muscle weakness, extreme stomach cramps, heavy sweating, blurred vision, difficulty breathing, or a very slow heartbeat. Do not wait for symptoms to become severe before seeking emergency medical care.

Diet & Lifestyle Advise

  • Time your meals carefully: If you have difficulty swallowing, schedule your meals for 30 to 45 minutes after taking Dostimine 60 mg Tablet 10's, when the medicine's effect is strongest.
  • Choose easy-to-chew foods: Opt for softer foods, gravies, and purées during times when muscle weakness is more pronounced to make eating safer and less exhausting.
  • Rest strategically: Plan periods of physical rest throughout the day, particularly before meals or activities that require more physical effort.
  • Keep a daily log: Track your doses, meal times, and muscle strength throughout the day to help your doctor optimise your treatment schedule.
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How Soon It Starts Working

  • The time required for Dostimine 60 mg Tablet 10's to start to work: The time required for Dostimine 60 mg Tablet 10's to start to work is 15 to 30 minutes after administration.
  • The time for which the effects of Dostimine 60 mg Tablet 10's last: The effect of Dostimine 60 mg Tablet 10's lasts for 6 to 8 hours.

What if you forget to take Dostimine 60 mg Tablet 10's

If you miss a dose, take it as soon as you remember. However, if it is within 1 hour of your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Dostimine 60 mg Tablet 10's at room temperature, ideally between 15°C and 30°C (59°F to 86°F), in a dry place away from direct heat, light, and moisture. •Do not store this medicine in the bathroom, as high humidity can degrade the tablets.

Drug Warnings

  • Differentiate weakness types: Both too little medicine (myasthenic crisis) and too much medicine (cholinergic crisis) can cause worsening muscle weakness and breathing difficulty, and the symptoms can appear similar. Do not change your dose yourself—seek urgent medical attention so your doctor can determine the cause and provide the appropriate treatment.
  • Check the packaging: Always inspect the product packaging and do not take the medicine if it has expired or if the tablets appear damp or crumbly.
  • Carry medical identification: Wear a medical alert bracelet or carry a card stating that you take Dostimine 60 mg Tablet 10's for myasthenia gravis, in case of emergencies.
  • Coordinate medical procedures: Tell any doctor, dentist, or surgeon that you are taking this medicine before undergoing any medical procedures or receiving anaesthetics.
  • Do not stop suddenly: Do not abruptly stop taking Dostimine 60 mg Tablet 10's without consulting your doctor, as this can cause a severe and rapid return of muscle weakness.

Drug-Drug Interactions

verifiedApollotooltip

Some medicines may affect how Dostimine 60 mg Tablet 10's works or increase the risk of side effects. Tell your doctor about all the medicines you are taking, including:

  • Muscle Relaxants: May interact with other medicines that affect muscle function, such as certain muscle relaxants used during surgery, which can have their effects blocked or altered.
  • Antibiotics and Heart Medicines: Combining this medicine with certain antibiotics (like aminoglycosides) or heart medications (like quinidine or beta-blockers) can sometimes worsen muscle weakness.
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No clinically significant food interactions are known with Dostimine 60 mg Tablet 10's when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MUSCLE STIMULANTS AND CHOLINESTERASE INHIBITORS]

FAQs

Dostimine 60 mg Tablet 10's is used to treat myasthenia gravis (muscle weakness). Besides this, it also treats paralytic ileus (a rare form of constipation), postoperative urinary retention, and prophylaxis to military exposure to any nerve-poisoning gas.
Dostimine 60 mg Tablet 10's works by stopping the excessive cholinesterase activity (an enzyme necessary for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, Dostimine 60 mg Tablet 10's helps in proper muscle functioning and prevents muscle weakness.
Dostimine 60 mg Tablet 10's is used as prophylaxis against the lethal effects of soman nerve agent poisoning especially by military. It is intended to be used in conjunction with atropine and pralidoxime therapy and protective garments and gas-mask.
Caution is needed in patients with asthma, breathing difficulty, wheezing and chronic cough as Dostimine 60 mg Tablet 10's may worsen the condition. Please consult your doctor before taking Dostimine 60 mg Tablet 10's if you have asthma or any breathing problems.
Talk to your doctor before taking Dostimine 60 mg Tablet 10's if you have hypertension (high blood pressure) as it may cause insignificant changes such as elevated blood pressure.
Anticholinergic drugs are often used in the treatment of glaucoma. Dostimine 60 mg Tablet 10's is a cholinergic inhibitor, and its use in patients with glaucoma may cause additive effects which could lead to night vision problems. Please consult your doctor before taking Dostimine 60 mg Tablet 10's if you have glaucoma.
Dostimine 60 mg Tablet 10's may cause side effects such as nausea, vomiting, diarrhoea, stomach pain, muscle cramps, blurred vision, rash and increased salivation. If these side effects persist or worsen, please consult your doctor.
Dostimine 60 mg Tablet 10's does not cause high blood pressure. In fact, intake of high dose of Dostimine 60 mg Tablet 10's can cause low blood pressure.
No, Dostimine 60 mg Tablet 10's should not be crushed or chewed. It should be taken as a whole with water.
Dostimine 60 mg Tablet 10's does not cause increase in heartbeats. On the other hand, it can be used in the treatment of increase in heartbeats in postural orthostatic tachycardia syndrome (POTS) where there is an abnormal increase in the heartbeats while standing from a lying position.
No, do not take Dostimine 60 mg Tablet 10's for constipation. It is used only when constipation occurs due to intestinal paralysis and strictly on prescription by the doctor.
Dostimine 60 mg Tablet 10's should not be taken by patients who are allergic to it, who have constipation or difficulty urinating, unless the doctor has advised to use this medicine.
If you have accidentally taken more than the required dose, seek medical help immediately. An overdose of Dostimine 60 mg Tablet 10's may cause nausea, vomiting, stomach pain, diarrhea, salivation, excessive sweating, blurred vision, difficulty in breathing, excessive weakness, and even paralysis.
No, Dostimine 60 mg Tablet 10's is not a steroid. It belongs to the group of medicines called anticholinesterases.
No, there is no proof that Dostimine 60 mg Tablet 10's has abuse potential.
No, Dostimine 60 mg Tablet 10's does not cause weight gain. However, if you gain weight, it may be due to inactivity related to muscle weakness in myasthenia gravis.
Yes, Dostimine 60 mg Tablet 10's is safe if used as advised by the doctor. Do not exceed the recommended dose.
You will typically begin to notice an improvement in your muscle strength within 30 to 45 minutes after taking Dostimine 60 mg Tablet 10's. The peak effect usually lasts for about 3 to 4 hours. Talk to your doctor if you do not feel any improvement.
Yes, you can take it with or without food. However, taking Dostimine 60 mg Tablet 10's with food, milk, or a light snack is highly recommended because it helps prevent common stomach side effects like cramps or nausea. Talk to your doctor or pharmacist for personalised advice.
The best timing depends on when your muscle weakness is most troublesome. Many patients find it most helpful to take a dose 30 to 45 minutes before meals to help with chewing and swallowing. Talk to your doctor to establish the best schedule for you.
No, Dostimine 60 mg Tablet 10's does not cure myasthenia gravis, but it is highly effective at managing and relieving the symptoms. It helps restore muscle strength so you can perform daily activities more easily. Talk to your doctor about long-term management plans.
If your weakness increases shortly after taking your dose, this could indicate that your dose is too high (a cholinergic crisis). You must seek medical attention immediately. Do not adjust your dose without consulting your healthcare provider. Talk to your doctor right away if you experience this.
It is highly advisable to avoid alcohol while taking Dostimine 60 mg Tablet 10's. Alcohol can increase drowsiness, upset your stomach, and interfere with how well you manage your muscle weakness. Talk to your doctor or pharmacist if you have questions about alcohol use.
Dostimine 60 mg Tablet 10's may be used during pregnancy when the expected benefits outweigh the potential risks, but treatment should always be supervised by your doctor. Babies born to mothers with myasthenia gravis or those taking Dostimine 60 mg Tablet 10's may occasionally develop temporary muscle weakness after birth and may require monitoring. If you are pregnant, planning a pregnancy, or breastfeeding, discuss your treatment plan with your doctor.
Some people may experience blurred vision, watering eyes, or mild dizziness while taking Dostimine 60 mg Tablet 10's. If you experience these symptoms, do not drive or operate heavy machinery until you know how the medicine affects you. Talk to your doctor for more safety guidelines.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

4-6, Bora Bazar St, Borabazar Precinct, Ballard Estate, Fort, Mumbai, Maharashtra 400001
Other Info - DOS0074

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