Doran-O Tablet is used in the treatment of vomiting (being sick) and nausea (feeling sick) that usually occur after cancer chemotherapy, radiation treatment or surgery. It may also be indicated in conditions such as gastroesophageal reflux disease (GERD) and ulcers in the stomach or intestine. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is forcible voluntary or involuntary emptying of stomach contents through the mouth.

Doran-O Tablet is a combination of two drugs, namely Omeprazole (proton pump inhibitor) and Ondansetron (anti-emetic). Omeprazole reduces the amount of acid the stomach produces and prevents excess acid from flowing back into the food pipe. Ondansetron works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting. 

Take Doran-O Tablet as prescribed. Your doctor will advise you on how often you should take it based on your medical condition. Doran-O Tablet may cause common side effects such as headache, a feeling of warmth, constipation, diarrhoea, or flatulence (wind). Most of these side effects of Doran-O Tablet do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor. 

If you are allergic to omeprazole, ondansetron, granisetron, dolasetron, pantoprazole, lansoprazole, rabeprazole, esomeprazole or other medicines, please tell your doctor. If you are pregnant or breastfeeding, inform your doctor. Drive only if you are alert after taking Doran-O Tablet . If you are taking nelfinavir (for HIV infection) or apomorphine (for Parkinson’s disease), do not take Doran-O Tablet .

Doran-O Tablet is used in the treatment of Nausea and Vomiting. The detailed uses of Doran-O Tablet are as follows:

• Nausea and vomiting: Doran-O Tablet is used in the treatment of nausea and vomiting, especially after chemotherapy, radiation therapy, or surgery.
• Gastroesophageal reflux disease (GERD): Doran-O Tablet is used in the treatment of Gastroesophageal reflux disease.
• Treatment of ulcers: Doran-O Tablet is used in the treatment of peptic ulcers and acid-related disorders with associated nausea.

• Doran-O Tablet should be taken one hour before a meal.
• It is usually taken once daily, preferably in the morning, or as prescribed by your doctor.
• Swallow Doran-O Tablet as a whole with a glass of water.
• Do not crush, chew, or break it.

Doran-O Tablet belongs to a group of medicines called gastrointestinal agents that prevent nausea and vomiting associated with conditions like cancer chemotherapy, radiotherapy, surgery, pregnancy and motion sickness. It may also be indicated in conditions such as gastroesophageal reflux disease (GERD) and ulcers in the stomach or intestine. It contains Omeprazole and Ondansetron. Omeprazole works by blocking the action of proton pumps that produce stomach acid. It reduces the amount of acid the stomach produces and prevents excess acid from flowing back into the food pipe. Ondansetron blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

If you are allergic to omeprazole, ondansetron, granisetron, dolasetron, pantoprazole, lansoprazole, rabeprazole, esomeprazole or other medicines, please tell your doctor. If you are pregnant or breastfeeding, inform your doctor. Drive only if you are alert after taking Doran-O Tablet . If you are taking nelfinavir (for HIV infection) or apomorphine (for Parkinson’s disease), do not take Doran-O Tablet . If you have problems with levels of sodium, magnesium, and potassium salts in your blood, inform your doctor before taking Doran-O Tablet .  Omeprazole in Doran-O Tablet may alter the results of some tests related to cancer. Therefore, tell your doctor, nurse or hospital staff you are taking Doran-O Tablet . Your doctor may advise you to stop taking this medicine for at least five days if you undergo certain tests.