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Doran-O Tablet contains Omeprazole and Ondansetron, which are used in the treatment of vomiting (being sick) and nausea (feeling sick) that usually occur after cancer chemotherapy, radiation treatment, or surgery. Omeprazole reduces the amount of acid the stomach produces and prevents excess acid from flowing back into the food pipe. Ondansetron works by blocking the action of serotonin, a chemical that stimulates the vomiting centre located in the brain. Thus, it prevents nausea and vomiting.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Bestochem Formulations (I) Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Doran-O Tablet

Doran-O Tablet is an oral prescription medication used to manage severe acid reflux, gastroesophageal reflux disease (GERD), and associated nausea or vomiting. It works by reducing the amount of acid produced in your stomach while simultaneously blocking the signals in your body that trigger the urge to vomit. This combined action helps protect your digestive tract and provides relief from uncomfortable stomach symptoms.

For the best results, you should take Doran-O Tablet consistently at the frequency prescribed by your doctor, usually once daily in the morning on an empty stomach. It is best to take this medication at least 30 to 60 minutes before your first meal of the day. Along with taking this medicine, making simple dietary changes, such as eating smaller meals and avoiding highly acidic foods, can significantly improve your recovery.

While taking Doran-O Tablet , you may experience mild and temporary side effects like headaches, constipation, or a mild stomach ache. Most people tolerate this medicine well, but you should contact your doctor immediately if you experience severe symptoms like a fast or irregular heartbeat, muscle weakness, or a severe skin rash.

Talk to your doctor before starting Doran-O Tablet if you have a history of liver damage, osteoporosis, low magnesium levels in your blood, or heart rhythm problems (such as QT prolongation). Also tell your doctor if you are taking medicines that can affect your heart rhythm. Do not take this medicine if you are allergic to any of its ingredients or if you are currently taking medications containing rilpivirine.

This medication can interact with other substances, including certain blood thinners, antifungals, and alcohol, which can increase the risk of side effects or make the treatment less effective. If you are pregnant, breastfeeding, or are an elderly individual, consult your healthcare provider to discuss whether Doran-O Tablet is safe and appropriate for your specific needs.

Uses of Doran-O Tablet

Doran-O Tablet is used to manage acid-related digestive conditions accompanied by nausea or vomiting. The detailed uses of Doran-O Tablet are as follows:

  • Gastroesophageal Reflux Disease (GERD) with nausea: Doran-O Tablet helps reduce excess stomach acid that causes heartburn and acid reflux, while also controlling the accompanying feelings of nausea.
  • Peptic ulcer disease: It assists in healing ulcers in the stomach or intestines by lowering acid levels, while preventing vomiting that can irritate the stomach lining.
  • Post-operative recovery: It manages acid reflux and nausea that commonly occur during recovery from surgery or certain medical procedures.

Key Benefits

Doran-O Tablet is a combination medicine used to manage acid-related stomach conditions accompanied by nausea or vomiting. Its two active ingredients work together to relieve symptoms, protect the digestive tract, and support recovery.

Benefits may include:

  • By reducing the amount of acid produced in the stomach, Doran-O Tablet helps relieve heartburn, acid reflux, and the burning sensation caused by excess stomach acid.
  • The anti-nausea component helps reduce nausea and vomiting, making it easier to eat, drink, and stay hydrated during recovery.
  • Lowering stomach acid allows the lining of the stomach and food pipe (oesophagus) to heal when damaged by excess acid.
  • By relieving multiple digestive symptoms at the same time, Doran-O Tablet can help you feel more comfortable and better able to carry out your daily activities.
  • Combining an acid-reducing medicine with an anti-nausea medicine in a single treatment simplifies therapy and may make it easier to follow the prescribed treatment plan.

Directions for Use

  • Doran-O Tablet should be taken one hour before a meal.
  • It is usually taken once daily, preferably in the morning, or as prescribed by your doctor.
  • Swallow Doran-O Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Doran-O Tablet Works

Doran-O Tablet combines two active ingredients that target different parts of your body to relieve stomach issues. Omeprazole: It is a proton pump inhibitor that works directly in the cells lining your stomach. It shuts down the tiny acid-producing pumps, significantly lowering the overall acidity in your stomach. This allows irritated tissues to heal and prevents acid from rising back up into your throat. Ondansetron: It blocks 5-HT3 (serotonin) receptors in the gut and brain. These receptors help transmit the signals that trigger nausea and vomiting. By blocking these receptors, ondansetron helps prevent and relieve nausea and vomiting. Together, these two ingredients provide a balanced approach to managing both acid irritation and nausea.
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Alcohol

Consult your doctor

If you have any concerns regarding alcohol consumption while taking Doran-O Tablet , please discuss them with your doctor.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, please inform your doctor before taking Doran-O Tablet .

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Breast Feeding

Consult your doctor

If you are a breastfeeding mother, please inform your doctor before taking Doran-O Tablet .

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Driving

Caution

Doran-O Tablet usually does not affect your ability to drive or operate machinery. However, if you experience visual disturbances or dizziness after taking Doran-O Tablet , avoid driving or operating machinery.

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Liver

Caution

If you have severe liver problems, inform your doctor, as a lower dose is recommended in such cases.

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Kidney

Consult your doctor

If you have kidney problems, please inform your doctor before taking Doran-O Tablet .

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Children

Caution

Doran-O Tablet should be used in dose and duration as advised by a doctor only. However, if you have any concerns regarding using Doran-O Tablet for children below 1 year, please consult a doctor.

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Heart

Caution

Doran-O Tablet should be used cautiously in heart patients due to the risk of rhythm changes like QT prolongation. Always consult a doctor to ensure safe use based on your cardiac condition.

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Geriatrics

Caution

Doran-O Tablet can be used in geriatric patients, but with caution due to age-related changes in drug metabolism. Older adults may be more prone to side effects like constipation, dizziness, or nutrient deficiencies, so medical supervision is recommended.

What if I have taken an overdose of Doran-O Tablet

If you suspect an overdose or experience severe symptoms like extreme drowsiness, confusion, rapid heart rate, or blurred vision, seek immediate medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Avoid trigger foods: Limit your intake of spicy, fatty, fried, and highly acidic foods (like citrus fruits and tomatoes), which can increase stomach acid and worsen nausea.
  • Eat smaller, frequent meals: Instead of three large meals, eat five or six small meals throughout the day to avoid overfilling your stomach and triggering reflux.
  • Stay upright after eating: Avoid lying down, bending over, or reclining for at least 2 to 3 hours after a meal to prevent acid from travelling back up into your oesophagus.
  • Limit caffeine and carbonated drinks: Coffee, tea, sodas, and energy drinks can relax the valve between your stomach and oesophagus, making acid reflux worse.
  • Elevate your head while sleeping: Raise the head of your bed by 6 inches using blocks or a wedge pillow to help keep acid in your stomach overnight.
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How Soon It Starts Working

The time required for Doran-O Tablet to start to work: The time required for Doran-O Tablet to show its action is unknown. The time for which the effects of Doran-O Tablet last: The duration of action for Doran-O Tablet is unknown.

What if you forget to take Doran-O Tablet

If you miss a dose of Doran-O Tablet , take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Doran-O Tablet at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Check the medicine before use: Always inspect your medication before taking it; do not use the tablet or capsule if the packaging is broken or the product looks damaged.
  • Monitor your treatment progress: Inform your doctor if your symptoms do not improve after a few days of consistent use.
  • Use only for the prescribed duration: Do not use Doran-O Tablet for longer than your doctor has prescribed, as long-term use of acid reducers can affect how your body absorbs certain vitamins and minerals, like vitamin B12 and magnesium.
  • Be cautious with activities requiring alertness: Avoid driving or operating machinery if you experience drowsiness, dizziness, or blurred vision after taking this medication.
  • Share your complete medication history: Keep a complete list of all other medications, herbal supplements, and over-the-counter products you take, and share it with your doctor or pharmacist before starting treatment.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (e.g., warfarin): May increase your risk of bleeding.
  • Antifungals (e.g., ketoconazole, itraconazole): Omeprazole reduces stomach acid, which can decrease the absorption and effectiveness of antifungal medicines.
  • Heart medications: May affect your heart rhythm and increase the risk of irregular heartbeats.
  • HIV medications (e.g., rilpivirine): May significantly lower the levels of the HIV medication in your blood.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid consuming alcohol while taking Doran-O Tablet , as alcohol can irritate your stomach lining, increase acid production, and worsen dizziness or drowsiness.
  • Caffeine: Limit intake of caffeinated beverages, which can trigger acid reflux and stomach discomfort. 
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[GASTROINTESTINAL AGENTS]

FAQs

Doran-O Tablet is used to treat Nausea and Vomiting.
Doran-O Tablet contains Omeprazole and Ondansetron. Omeprazole reduces the amount of acid the stomach produces and prevents excess acid from flowing back into the food pipe. Ondansetron blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.
Doran-O Tablet may cause constipation as a side effect. It is not necessary for everyone taking Doran-O Tablet to experience this side effect. However, if the condition persists or worsens, please consult a doctor.
Doran-O Tablet should be used with caution in patients suffering from liver problems. Inform your doctor if you have any liver problems before taking Doran-O Tablet so that the dose may be adjusted appropriately.
Yes, you should take Doran-O Tablet on an empty stomach, ideally 30 to 60 minutes before your morning meal. This helps the acid-reducing component work most effectively. Talk to your doctor if you have questions about the timing of your dose.
Some people may experience mild drowsiness or fatigue while taking Doran-O Tablet . If you feel sleepy or dizzy, avoid driving, riding a bicycle, or operating heavy machinery until you know how the medicine affects you. Talk to your doctor if this symptom persists.
It is highly recommended to avoid alcohol while taking Doran-O Tablet . Alcohol can irritate your stomach, increase acid production, and worsen symptoms like dizziness or drowsiness. Talk to your doctor or pharmacist for more personalised advice.
You should only take Doran-O Tablet during pregnancy if your doctor determines that the benefits outweigh the potential risks. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before starting this medication.
Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular timing. Do not take two doses at once to make up for a missed dose. Talk to your doctor or pharmacist if you frequently miss doses.
No, you must swallow Doran-O Tablet whole with a glass of water. Crushing, chewing, or breaking the medicine can ruin the protective coating, which prevents it from being destroyed by stomach acid or irritating your digestive system. Talk to your doctor if you have difficulty swallowing pills.
Doran-O Tablet is typically prescribed for short-term relief. Long-term use of acid-reducing medicines can lead to issues like low magnesium levels or bone weakness. Always use this medicine for the exact duration recommended by your physician. Talk to your doctor to discuss long-term management options.

Disclaimer

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Country of origin

INDIA

Manufacturer/Marketer address

G-54 3rd FLOOR LAXMI NAGAR VIKAS MARG DELHI -110092
Other Info - DOR0020
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