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  3. Dopnauz Injection 2 ml

Dopnauz Injection 2 ml, Pack of 1 INJECTION
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Dopnauz Injection 2 ml is used to treat Postoperative nausea and vomiting (PONV). It contains Amisulpride, which helps restore the balance of certain natural substances in the brain. Also, it stops nausea by blocking the D2 receptors located in the chemoreceptor trigger zone of the brain, which is responsible for inducing vomiting. Common side effects of Dopnauz Injection 2 ml are constipation, weight gain, decreased blood pressure, dystonia (involuntary muscle contractions), akathisia (inability to stay still), parkinsonism, and increased prolactin levels in the blood.
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Composition :

AMISULPRIDE-5MG

Manufacturer/Marketer :

La Renon Healthcare Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Dopnauz Injection 2 ml

Dopnauz Injection 2 ml belongs to a group of medicines called 'antipsychotics' used to treat postoperative nausea and vomiting. Nausea is an uneasy feeling in which the person feels an urge to vomit, whereas vomiting is an uncontrollable reflex that expels the stomach's contents through the mouth.

Dopnauz Injection 2 ml contains Amisulpride, which helps restore the balance of certain natural substances in the brain. Dopnauz Injection 2 ml stops nausea by blocking the D2 receptors located in the chemoreceptor trigger zone - CTZ of the brain responsible for inducing vomiting.

Dopnauz Injection 2 ml will be administered by a qualified healthcare doctor. In some cases, you may experience common side effects such as dryness in the mouth, constipation, weight gain, decreased blood pressure, dystonia (involuntary muscle contractions), akathisia (inability to stay still), parkinsonism, increased prolactin level in blood. Most of these side effects do not require medical attention and gradually subside over time. However, if the side effects persist or worsen, please consult your doctor.

Dopnauz Injection 2 ml should be avoided if you are allergic to it or any other medicines, Dopnauz Injection 2 ml is not recommended for children below 18 years of age. Let your doctor know if you are pregnant or breastfeeding before receiving Dopnauz Injection 2 ml. Dopnauz Injection 2 ml should be used with extreme caution in elderly patients above 65 years of age as there is an increased risk of severe adverse effects. If you have breast cancer, pheochromocytoma (tumour of the adrenal gland), pituitary gland prolactinoma (tumour of the pituitary gland), fits, Parkinson’s disease, kidney or heart problems, inform your doctor before starting treatment with Dopnauz Injection 2 ml. Avoid driving or operating machines after administration of Dopnauz Injection 2 ml as it may cause drowsiness or dizziness.

Uses of Dopnauz Injection 2 ml

Dopnauz Injection 2 ml is used in the treatment of postoperative nausea and vomiting (PONV). The detailed uses of Dopnauz Injection 2 ml are as follows:<br/>• Preventing Postoperative Nausea: Dopnauz Injection 2 ml helps to prevent nausea that occurs after surgery, reducing patient discomfort and promoting smoother recovery.<br/>• Treating Postoperative Vomiting: Dopnauz Injection 2 ml helps treat vomiting that occurs after surgery, minimizing complications and supporting patient well-being.<br/>

Directions for Use

• Your doctor will determine the dosage and frequency depending on your condition.• Dopnauz Injection 2 ml will be administered by a healthcare professional.• Do not self-administer.

Medicinal Benefits

Dopnauz Injection 2 ml contains Amisulpride, a group of medicines called antipsychotics used to treat postoperative nausea/vomiting. Dopnauz Injection 2 ml has anti-emetics properties hence used either in monotherapy or in combination with other antiemetic drugs to prevent nausea and vomiting, which might occur after surgery. Dopnauz Injection 2 ml stops the sensation of vomiting/nausea by blocking the D2 receptors located in the chemoreceptor trigger zone - CTZ of the brain responsible for inducing vomiting.

How Dopnauz Injection 2 ml Works

Dopnauz Injection 2 ml contains Amisulpride, which helps restore the balance of certain natural substances in the brain. Dopnauz Injection 2 ml stops nausea by blocking the D2 receptors located in the chemoreceptor trigger zone - CTZ of the brain responsible for inducing vomiting.

Storage

• Store in a cool and dry place away from sunlight.• Keep Dopnauz Injection 2 ml out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Dopnauz Injection 2 ml

Since Dopnauz Injection 2 ml is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

  • Do not use Dopnauz Injection 2 ml if you are allergic (hypersensitive) to olanzapine or any other ingredients present in this medicine or have a medical history of prolactin-dependent tumour or breast cancer, phaeochromocytoma (a tumour on the adrenal gland), pituitary tumour. 
  • Dopnauz Injection 2 ml should not be given to children as safety has not been established. 
  • Use Dopnauz Injection 2 ml with extreme caution in elderly patients above 65 years of age as there is an increased risk of severe adverse effects. 
  • If you are pregnant or breastfeeding, please consult a doctor before taking Dopnauz Injection 2 ml. 
  • Dopnauz Injection 2 ml may impair fertility, so inform your doctor if you are planning for pregnancy. 
  • Inform your doctor if you are previously diagnosed with kidney disease, liver disease, epilepsy or seizures (fits), Parkinson's disease, unusual heart rate (rhythm), slow heartbeat (less than 55 beats per minute), low potassium levels in your blood, prolonged QT interval (heart conduction problem) if you or someone else in your family has a history of blood clots, heart problems, stroke, diabetes, have a low number of white blood cells (agranulocytosis), leucopenia (blood disorder). 
  • Dopnauz Injection 2 ml may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Dopnauz Injection 2 ml as it could lead to increased drowsiness and dizziness. 

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Drink fluids to stay hydrated. Use oral rehydration solutions (ORS) to replace lost electrolytes.
  • Avoid solid foods until the vomiting stops.
  • Avoid foods that might cause stomach upset.
  • Take ample rest. Avoid any activity immediately after eating.
  • Consume plain, light foods such as bread and biscuits.
  • Avoid food with strong flavours and fried food.
  • Ginger tea might help in proper digestion.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Dopnauz Injection 2 ml Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid consumption of alcohol while receiving Dopnauz Injection 2 ml as it may lead to increased dizziness and drowsiness.

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Pregnancy

Caution

Dopnauz Injection 2 ml should be used in pregnant women only when prescribed by a doctor. If you are pregnant, inform your doctor before starting treatment with Dopnauz Injection 2 ml. Your doctor will prescribe only if the benefits outweigh the risks. Do not take Dopnauz Injection 2 ml during the last three months of pregnancy; your baby may suffer from agitation, increased muscle tension, involuntary trembling of the body, sleepiness, or breathing problems.

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Breast Feeding

Caution

Dopnauz Injection 2 ml is not recommended for use in nursing mothers as it may cause side effects in newborn infants.

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Driving

Caution

Dopnauz Injection 2 ml may cause dizziness, drowsiness and uncontrolled movements. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Take Dopnauz Injection 2 ml with caution if you have a history of liver diseases/conditions. Your doctor may adjust the dose if required. Dopnauz Injection 2 ml is not recommended for patients with severe liver disease. Inform your doctor immediately if you experience fatigue, loss of appetite, nausea, vomiting, abdominal pain or yellow discolouration of the eyes or skin.

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Kidney

Caution

Dopnauz Injection 2 ml should be used in patients with kidney diseases only when prescribed by a doctor. Dose adjustments and regular monitoring of electrolytes may be required as it may alter electrolyte levels in the body.

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Children

Caution

Dopnauz Injection 2 ml should not be given to children as safety and effectiveness were not established.

Have a query?

FAQs

Dopnauz Injection 2 ml is used to treat Postoperative nausea and vomiting (PONV).

Dopnauz Injection 2 ml contains Amisulpride, which works by modulating certain chemical messengers (dopamine D2) in the brain, which helps regulate nausea and vomiting.

The oral form of Amisulpride can be used to treat psychotic disorders like schizophrenia, bipolar disorder, and depression. However, you should not take this medication without a doctor’s advice.

Dopnauz Injection 2 ml may affect fertility as it may cause hyperprolactinemia (excessive levels of prolactin hormone in the blood), resulting in amenorrhea (absence of menstrual periods), anovulation (lack of egg release) and impaired fertility.

Dopnauz Injection 2 ml is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people, as it may cause severe adverse effects, including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Dopnauz Injection 2 ml.

Stopping Dopnauz Injection 2 ml abruptly can cause withdrawal symptoms, and stopping it too early could make your illness come back. Please consult your doctor if you want to stop taking Dopnauz Injection 2 ml.

Take Dopnauz Injection 2 ml with caution if you have diabetes, as it may increase the risk of having diabetes. It is advised to monitor your blood sugar levels regularly while receiving Dopnauz Injection 2 ml.

Country of origin

India

Manufacturer/Marketer address

Behind Rajpath Club, Kensville Road, Opp. Infostretch Building, Off S.G. Highway, Ahmedabad- 380059, Gujarat- India
Other Info - DOP0054

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:21 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.548.pdf
  2. https://www.mayoclinic.org/drugs-supplements/amisulpride-intravenous-route/description/drg-20484188#:~:text=Amisulpride%20injection%20is%20used%20alone,that%20cause%20nausea%20and%20vomiting.
  3. https://medlineplus.gov/druginfo/meds/a622062.html
  4. https://www.rxlist.com/barhemsys-drug.htm#indications
  5. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/209510s000lbl.pdf
  6. https://my.clevelandclinic.org/health/drugs/23783-amisulpride-injection

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