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compositionComposition:DOPAMINE-200MG
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Prescription Medicine
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Dopacef 200mg Injection is used to treat low blood pressure or shock after a heart attack, trauma (injury), blood poisoning or kidney failure. It contains Dopamine, which works by increasing blood flow to the muscles and kidneys. Additionally, it may be used in people with congestive heart failure (heart failure due to the build-up of blood or fluid) to help the heart pump better by increasing the heart's pumping efficiency. Dopamine may also be used in combination with other medicines to treat low blood pressure that occurs after open heart surgery.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DOPAMINE-200MG

Manufacturer/Marketer :

Chandra Bhagat Pharma Ltd

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Dopacef 200mg Injection

Dopacef 200mg Injection is a prescription injection used to treat low blood pressure, low cardiac output, and poor blood flow to vital organs during shock. It is commonly used in emergency situations, such as after a heart attack, severe blood loss, or blood poisoning from a severe infection. This medicine helps restore normal blood flow and blood pressure to keep your body functioning during critical medical events.

Since Dopacef 200mg Injection is given as a continuous injection into a vein, it is only used in hospitals or clinical settings under close medical supervision. The frequency and duration of this treatment depend entirely on how your heart and blood pressure respond to the medicine. Because this is an emergency treatment, standard daily diet and long-term lifestyle changes are managed by your care team once your condition stabilises.

Some people may experience side effects such as an irregular heartbeat, nausea, headache, or a feeling of anxiety during the infusion. It is vital to tell your healthcare provider immediately if you feel chest pain, shortness of breath, or coldness in your fingers or toes. Your doctor will monitor your vital signs closely to manage these risks.

Do not receive this medicine if you have a specific type of adrenal gland tumor called a pheochromocytoma, or if you have an uncorrected fast or irregular heartbeat. Before receiving this treatment, your doctor needs to know if you have a history of blood vessel disease, frostbite, or thyroid problems. Talk to your doctor if you have any of these conditions.

This medicine can interact severely with certain medications, such as monoamine oxidase inhibitors (MAOIs), which can cause a sudden and dangerously high increase in blood pressure. Tell your healthcare team about all other medicines you are taking, and let them know if you are pregnant, breastfeeding, or if the patient is an elderly individual, as these groups may require extra monitoring.

Uses of Dopacef 200mg Injection

Dopacef 200mg Injection helps improve blood pressure, heart function, and blood flow during life-threatening medical conditions. Your doctor may prescribe it for the following conditions:

  • Shock: Helps raise extremely low blood pressure and improves blood flow to major organs during septic, cardiogenic, or traumatic shock.
  • Severe Low Blood Pressure (Hypotension): Raises blood pressure to safe levels when it drops dangerously low due to surgery, trauma, or severe illness.
  • Heart Failure with Low Blood Pressure: May be used in selected emergency situations, such as severe heart failure with dangerously low blood pressure or cardiogenic shock, to support heart function and blood circulation while other treatments are started.

Key Benefits

Using Dopacef 200mg Injection as prescribed helps restore blood pressure and improve blood flow during critical medical emergencies. Here are the key benefits you can expect:

  • Rapidly stabilises blood pressure: Dopacef 200mg Injection quickly raises dangerously low blood pressure, ensuring that vital organs such as the brain, heart, and kidneys receive enough oxygen-rich blood.
  • Supports heart function: By improving the heart's pumping ability, it helps reduce the workload on a failing heart and promotes faster stabilisation during intensive care.
  • Improves organ perfusion: By restoring adequate circulation, Dopacef 200mg Injection helps protect vital organs from damage caused by prolonged low blood pressure.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Dopacef 200mg Injection will be administered by the doctor or healthcare professional in a medical setting.
  • Do not self-administer.

How Dopacef 200mg Injection Works

Dopacef 200mg Injection contains dopamine, a vasopressor and inotropic medicine that improves blood pressure, heart function, and blood flow to vital organs. Dopacef 200mg Injection acts on different receptors in the body depending on the dose administered. At lower doses, it may increase blood flow to the kidneys and urine output in some patients. However, current evidence does not support using low-dose Dopacef 200mg Injection specifically to protect kidney function. At moderate doses, it stimulates the heart muscle, allowing the heart to pump more strongly and efficiently, which increases blood flow throughout the body. At higher doses, it narrows the blood vessels, raising blood pressure to a safer and more stable level. These combined effects help restore circulation and maintain adequate blood flow to vital organs during critical illness.
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Alcohol

Caution

Avoid consumption of alcohol. Please discuss with your doctor if you have concerns.

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Pregnancy

Consult your doctor

Limited data is available on the effect of Dopacef 200mg Injection in pregnancy. Hence, if you are pregnant or planning for pregnancy, inform your doctor before receiving Dopacef 200mg Injection.

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Breast Feeding

Consult your doctor

Limited data is available on the effect of Dopacef 200mg Injection on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Dopacef 200mg Injection.

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Driving

Not applicable

Dopacef 200mg Injection is generally intended for use in hospitalized patients.

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Liver

Consult your doctor

If you have liver problems, inform your doctor before receiving Dopacef 200mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have kidney problems, inform your doctor before receiving Dopacef 200mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Dopacef 200mg Injection is not recommended for children as the safety and effectiveness were not established in children.

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Heart

Consult your doctor

Please consult your doctor if you have any heart problems before taking Dopacef 200mg Injection.

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Geriatrics

Caution

Dopacef 200mg Injection should be used with caution in elderly patients. Please consult your doctor before use.

What if I have taken an overdose of Dopacef 200mg Injection

Since this medicine is given under close medical supervision with continuous monitoring, an overdose is rare. If an overdose occurs, symptoms like extremely high blood pressure or an irregular heartbeat will be managed immediately by the healthcare team by slowing down or stopping the injection.

Diet & Lifestyle Advise

  • Follow fluid restriction guidelines: If you are recovering from heart failure, strictly follow the fluid intake limits recommended by your medical team to avoid overloading your heart.
  • Monitor salt intake: Reduce dietary sodium as advised by your healthcare provider to help manage blood pressure and prevent fluid buildup in your body.
  • Rest during recovery: Allow your body plenty of time to rest and recover after receiving this intensive therapy, avoiding sudden physical exertion.
  • Avoid sudden position changes: As you recover and begin to move around, stand up slowly from a sitting or lying position to prevent dizziness or sudden drops in blood pressure.
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How Soon It Starts Working

The time required for Dopacef 200mg Injection to start to work: Dopacef 200mg Injection ideally shows its action within 5 minutes after administration. The time for which the effects of Dopacef 200mg Injection last: The effect of Dopacef 200mg Injection lasts for less than 10 minutes.

What if you forget to take Dopacef 200mg Injection

Because this medicine is given continuously by healthcare professionals in a hospital, it is highly unlikely that you will miss a dose. If the infusion is temporarily interrupted, hospital staff will address it immediately.

Storage

• Dopacef 200mg Injection is typically stored in a hospital pharmacy or clinical area at 20°C to 25°C.

Drug Warnings

  • Monitor the injection site closely: Tell your nurse or doctor immediately if you feel pain, burning, coldness, or see swelling where the IV is inserted, as the medicine can damage surrounding tissue if it leaks.
  • Regularly check vital signs: Expect continuous monitoring of your blood pressure, heart rate, and urine output while receiving this medication.
  • Report chest pain: Alert medical staff right away if you experience any chest tightness, fluttering in your chest, or difficulty breathing during the infusion.
  • Avoid sudden movement of the IV line: Keep the arm or area with the IV line as still as possible to prevent the needle or catheter from shifting.

Drug-Drug Interactions

verifiedApollotooltip
  • Monoamine Oxidase Inhibitors (MAOIs): Combining these medicines can lead to a severe, life-threatening rise in blood pressure.
  • Inhaled Anaesthetics (like halothane): May increase the risk of severe irregular heartbeats when used alongside Dopacef 200mg Injection.
  • Tricyclic Antidepressants: Can increase the blood-pressure-raising effects of Dopacef 200mg Injection, requiring careful dose adjustment.
  • Beta-blockers: Can counteract the heart-stimulating effects of Dopacef 200mg Injection, reducing its effectiveness.

Drug-Drug Interactions

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How does the drug interact with Dopacef 200mg Injection:
When Selegiline is taken with Dopacef 200mg Injection, may significantly increase high blood pressure.

How to manage the interaction:
There may be a possibility of interaction between Dopacef 200mg Injection and Selegiline, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dopacef 200mg Injection:
Coadministration of Tranylcypromine with Dopacef 200mg Injection can cause severe high blood pressure.

How to manage the interaction:
Taking Dopacef 200mg Injection with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Dopacef 200mg Injection:
Taking Dopacef 200mg Injection with Imipramine can increase the levels and action of Dopacef 200mg Injection

How to manage the interaction:
Co-administration of Dopacef 200mg Injection with Imipramine can result in an interaction, but it can be taken if your doctor has advised it. Maintain your blood pressure regularly. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dopacef 200mg Injection:
Coadministration of Nortriptyline with Dopacef 200mg Injection may increase the risk or severity of side effects like hypertension (high blood pressure), throbbing headache, tremors, palpitation, chest pain, and cardiac dysrhythmia (irregular heartbeats).

How to manage the interaction:
Although there is a possible interaction, Nortriptyline can be taken with Dopacef 200mg Injection if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood pressure levels is advised. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dopacef 200mg Injection:
Co-administration of Dopacef 200mg Injection with clomipramine can interact with each other.

How to manage the interaction:
Although taking clomipramine and Dopacef 200mg Injection together can cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dopacef 200mg Injection:
Co-administration of Amitriptyline and Dopacef 200mg Injection may increase the risk of blood pressure.

How to manage the interaction:
Dopacef 200mg Injection and amitriptyline could interact, but they can still be taken if they are prescribed by a doctor. Dopacef 200mg Injection and amitriptyline shouldn't be combined unless a medical emergency arises. Even when you are lying down or have your head up, it is crucial to keep a watchful eye on your blood pressure. Also, keep an eye out for any unusual side effects. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Dopacef 200mg Injection:
Doxepin can enhance the blood pressure-raising effects of Dopacef 200mg Injection.

How to manage the interaction:
There may be a possibility of interaction between Dopacef 200mg Injection and Doxepin, but it can be taken if prescribed by a doctor. If you experience any symptoms, contact your doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Dopacef 200mg Injection when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[VASOPRESSORS]

FAQs

Dopacef 200mg Injection is used to treat Low blood pressure and shock after a heart attack, trauma (injury), blood poisoning and kidney failure.
Dopacef 200mg Injection contains Dopamine that works by increasing blood flow to the muscles and increasing the pumping efficiency of the heart. Also, it increases blood flow to the kidneys.
Dopacef 200mg Injection should be used with caution in diabetic patients. Therefore, if you have diabetes, inform your doctor before receiving Dopacef 200mg Injection.
Dopacef 200mg Injection may cause a headache as a common and temporary side effect. However, if the condition persists or worsens, please inform your doctor.
Dopacef 200mg Injection may cause common side effects such as headache, nausea, shortness of breath, chest pain, or irregular heartbeat. Most of these side effects do not require medical attention and will subside over time. However, if the side effects persist, please consult your doctor.
Dopacef 200mg Injection primarily relieves symptoms rather than treating the underlying disease. It is used to manage conditions such as low blood pressure or shock after a heart attack, trauma (injury), blood poisoning, or kidney failure. However, it does not address the root causes of these conditions.
Dopacef 200mg Injection is not habit-forming. It contains dopamine, which is a substance that occurs naturally in the body, and its administration does not typically create the same effects that are associated with addictive substances.
This medicine is injected directly into a vein as a continuous infusion (drip) by a trained healthcare professional in a hospital setting. Talk to your doctor or nurse for more information.
Yes, because Dopacef 200mg Injection works to raise blood pressure, a high dose can sometimes cause blood pressure to become too high. Your healthcare team will continuously monitor your vital signs to keep your blood pressure in a safe range. Talk to your doctor if you have concerns.
You must tell your healthcare provider immediately if you feel any pain, burning, coldness, or swelling around your IV site, as the medicine can cause tissue damage if it leaks out of the vein. Talk to your doctor or nurse right away.
Dopacef 200mg Injection is typically only used during pregnancy if it is a life-saving emergency and the benefits outweigh the potential risks to the baby. Talk to your doctor to understand the risks and benefits in emergency situations.
This medicine stimulates the heart to pump more strongly, which can sometimes cause a fast or irregular heartbeat. Continuous monitoring allows doctors to adjust the dose immediately if your heart rate goes too high. Talk to your doctor if you feel your heart racing.
Yes, Dopacef 200mg Injection can interact with several medications, including certain antidepressants and anesthetics, which can affect how the medicine works or cause severe side effects. Talk to your doctor or pharmacist to review your medication history.
Yes. Dopacef 200mg Injection may be used in infants and children in emergency situations when recommended by a specialist. The dose is carefully calculated based on the child's weight and medical condition, and treatment is given under continuous monitoring in a hospital.
Dopacef 200mg Injection is usually given only until your blood pressure, heart function, and circulation have improved or another treatment can take over. Your healthcare team will gradually reduce the infusion while closely monitoring your blood pressure, heart rate, and other vital signs to ensure your condition remains stable.

Disclaimer

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Country of origin

India
Other Info - DOPA413
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