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compositionComposition:VALPROIC ACID-500MG
prescriptionPrescription Medicine
Doncorate 500mg Tablet ER

Doncorate 500mg Tablet ER is used to treat seizures and manage manic episodes in bipolar disorder. It also helps prevent migraine attacks. It supports better brain stability and reduces symptom frequency. This helps improve daily functioning and overall quality of life.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

VALPROIC ACID-500MG

Manufacturer/Marketer :

Bondane Pharma

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Doncorate 500mg Tablet ER

Doncorate 500mg Tablet ER is used to treat epilepsy/seizures/fits. In addition, Doncorate 500mg Tablet ER also treats manic episodes associated with bipolar disorder. Additionally, it can prevent migraine symptoms (such as headache).

Doncorate 500mg Tablet ER contains valproic acid, which helps stabilise abnormal brain activity. It supports effective seizure control and helps calm overactive neural activity. It also helps manage mood changes in bipolar disorder and reduces the frequency of migraine attacks. This improves neurological balance and supports better functioning.

Administer Doncorate 500mg Tablet ER with food to prevent gastrointestinal upset. You may sometimes experience nausea, upset stomach or stomach pain, tremors (shakes), sleepiness, headache, weight gain and thinning hair. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Inform your doctor if you are allergic to any components present in Doncorate 500mg Tablet ER. If you are pregnant, do not take Doncorate 500mg Tablet ER because it may cause serious congenital defects. Doncorate 500mg Tablet ER is generally not recommended during breastfeeding; consult your physician before taking Doncorate 500mg Tablet ER.

Uses of Doncorate 500mg Tablet ER

Doncorate 500mg Tablet ER is used for the treatment of epilepsy (seizures), bipolar disorder, and migraine. The detailed uses of Doncorate 500mg Tablet ER are as follows:

  • Controls Seizures: Doncorate 500mg Tablet ER helps prevent and control seizures by calming overactive neural activity.
  • Manages Bipolar Disorder: Doncorate 500mg Tablet ER helps to control manic episodes and stabilise mood in individuals with bipolar disorder.
  • Prevents Migraine Headaches: Doncorate 500mg Tablet ER is also prescribed as a preventive treatment to reduce the frequency and severity of migraine attacks.

Have a query?

Directions for Use

  • Doncorate 500mg Tablet ER can be taken with food to avoid stomach upset.
  • It is usually taken twice daily; however, your doctor may adjust the dosage and timing based on your medical condition and response to treatment.
  • Swallow Doncorate 500mg Tablet ER as a whole with a glass of water.
  • Do not crush or chew this medication.

Key Benefits

Doncorate 500mg Tablet ER, when used as prescribed, may provide the following benefits:

For Controls Seizures:

  • Helps stabilise abnormal electrical activity in the brain.
  • Reduces sudden episodes of excessive brain stimulation

For Managing Bipolar Disorder:

  • Helps maintain emotional balance.
  • Reduces the intensity and frequency of extreme mood changes

For Preventing Migraine Headaches:

  • Helps reduce the risk of recurrent severe headaches.
  • Reduces the impact of migraine on daily life.

How Doncorate 500mg Tablet ER Works

Doncorate 500mg Tablet ER contains valproic acid, which helps calm excessive nerve activity in the brain. As a result, it aids in controlling seizures. In bipolar disorder, Doncorate 500mg Tablet ER raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. In migraine, Doncorate 500mg Tablet ER limits the transmission of pain, thereby preventing migraine.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Doncorate 500mg Tablet ER

Avoid exceeding the prescribed dose, as this may lead to adverse effects. Symptoms of adverse effects may include sleepiness, an irregular heartbeat, and coma (loss of consciousness). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Before taking the Doncorate 500mg Tablet ER, let your doctor know about all your medical conditions, sensitivities, and all medications you are using.
  • Inform your doctor if you are pregnant, suspect you are pregnant, plan to have a baby, or are breastfeeding.
  • You should not become pregnant during treatment with Doncorate 500mg Tablet ER.
  • Consult your doctor immediately if you become pregnant while taking Doncorate 500mg Tablet ER.
  • Alcohol should be avoided during treatment with this medicine.
  • You must not drive or operate machinery while taking Doncorate 500mg Tablet ER.

Diet & Lifestyle Advise

Diet:

  • Follow a high-fat, low-carbohydrate diet if advised by your doctor.
  • Maintain a balanced meal plan to support overall health.

Physical Activity:

  • Exercise regularly to help maintain a healthy weight and general fitness.

Safety & Preparedness:

  • Keep a seizure response plan and inform people around you.
  • Make simple home safety changes to reduce injury risk.
  • Identify and avoid known seizure triggers.
  • Use an alarm or emergency device to call for help during a seizure.

Rest & Sleep:

  • Get enough rest and sleep to reduce seizure risk.

Habits:

  • Avoid smoking and alcohol consumption.

Stress Management:

  • Practice meditation or yoga to reduce stress and improve coping ability.

Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

All Substitutes & Brand Comparisons

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Alcohol

Unsafe

Do not consume alcohol while taking Doncorate 500mg Tablet ER as alcohol can worsen the side effects of the Doncorate 500mg Tablet ER, including sleepiness and dizziness.

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Pregnancy

Unsafe

Doncorate 500mg Tablet ER is a Category D pregnancy drug. It is not recommended for use during pregnancy as it may cause an increase in the risk of a cleft lip, which is a congenital disability in the unborn baby. If you are a female able to have a baby, you must use an effective method of birth control (contraception) without interruption during your entire treatment with Doncorate 500mg Tablet ER.

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Breast Feeding

Caution

Doncorate 500mg Tablet ER passes into breast milk and may harm your infant. Please consult a doctor if you are breastfeeding before taking Doncorate 500mg Tablet ER. Breastfed infants are at risk for valproic acid-induced hepatotoxicity, so infants should be monitored for jaundice and other signs of liver damage during maternal therapy.

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Driving

Unsafe

Doncorate 500mg Tablet ER may cause dizziness, drowsiness, or fatigue in some individuals. Therefore, avoid driving if you feel drowsy, dizzy or tired after taking Doncorate 500mg Tablet ER.

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Liver

Caution

Inform your doctor before taking the Doncorate 500mg Tablet ER if you have a history of liver diseases. Extreme caution is recommended in patients with impaired liver function. Your doctor will weigh the benefits and potential risks before prescribing Doncorate 500mg Tablet ER.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please inform your doctor if you have kidney impairment.

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Children

Caution

Use is not recommended for children under 10 years old. Your doctor will decide the dose based on your child's condition if they are more than ten years old.

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Heart

Caution

Doncorate 500mg Tablet ER can be used cautiously in patients with heart disease if prescribed by a physician.

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Geriatrics

Caution

Doncorate 500mg Tablet ER can be given to elderly patients with extreme caution if prescribed by a physician.

FAQs

Doncorate 500mg Tablet ER is used to treat epilepsy/seizures/fits. In addition, it also helps treat manic episodes associated with bipolar disorder and prevent migraine symptoms (like a headache).

Doncorate 500mg Tablet ER decreases the excessive and abnormal nerve activity in the brain. Thereby helping in controlling seizures.

Doncorate 500mg Tablet ER helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect.

Doncorate 500mg Tablet ER limits the transmission of nerve pain, thereby preventing migraine headaches. Migraines are a neurological condition characterised by intense headaches.

Doncorate 500mg Tablet ER may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective method of contraception during the treatment with Doncorate 500mg Tablet ER. Avoid getting pregnant while taking Doncorate 500mg Tablet ER as it could lead to serious birth defects. Do not stop taking Doncorate 500mg Tablet ER and consult your doctor immediately if you become pregnant.

Doncorate 500mg Tablet ER may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Doncorate 500mg Tablet ER may cause common side effects such as nausea, vomiting, headache, sleepiness, tremor, weakness, dizziness, stomach pain, and weight gain. If these side effects persist or worsen, please consult your doctor.

Doncorate 500mg Tablet ER contains Valproic acid as its active ingredient.

Take Doncorate 500mg Tablet ER with food to avoid stomach upset or as advised by your doctor.

You are recommended to avoid alcohol consumption while taking Doncorate 500mg Tablet ER as it may worsen the side effects of the Doncorate 500mg Tablet ER, including sleepiness and dizziness.

No, Doncorate 500mg Tablet ER does not cause addiction. However, Doncorate 500mg Tablet ER should be used as per the dose and duration prescribed by your doctor. Do not self-medicate.

Doncorate 500mg Tablet ER does not cure epilepsy; it only helps prevent seizures. However, you must take Doncorate 500mg Tablet ER for as long as your doctor advises. If you face any difficulty while taking Doncorate 500mg Tablet ER, consult your doctor.

If you stop taking Doncorate 500mg Tablet ER suddenly, it may increase the risk of recurrence of seizures. Therefore, it should be stopped gradually. If you feel the need to discontinue Doncorate 500mg Tablet ER, please consult your physician.

Some birth control pills (oestrogen-containing birth control pills) may lower the levels of Doncorate 500mg Tablet ER in blood. Thus, inform your doctor if you are using birth control pills and discuss with your doctor about a suitable method of contraception.

Doncorate 500mg Tablet ER is safe for long-term use in many patients when prescribed by a physician. In rare cases, prolonged use of Doncorate 500mg Tablet ER may weaken bones, thereby increasing the risk of fractures (osteopenia and osteoporosis). Get regular checkups for bone health if you have been taking Doncorate 500mg Tablet ER for a long time.

Doncorate 500mg Tablet ER may cause hair thinning, hair colour changes and even hair loss. If you have any concerns about this, please ask your doctor whether it is possible to reduce the dose of Doncorate 500mg Tablet ER. Your hair may regrow after either lowering your dose or changing medication.

Country of origin

India
Other Info - DO77969

Disclaimer

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