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  1. Home
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  3. Domril 1mg/ml Syrup

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Domril 1mg/ml Syrup, Pack of 1 Syrup
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Domril 1mg/ml Syrup is used to treat nausea and vomiting in adults and adolescents 12 years or older. Besides this, it also helps treat indigestion. It contains Domperidone, which prevents nausea and vomiting by blocking certain receptors (such as dopamine and serotonin) that stimulate the vomiting centre in the brain. It also increases the motility of the upper gastrointestinal tract and helps decrease gastric emptying time. The most common side effect of this medicine is dry mouth.

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Composition :

DOMPERIDONE-1MG/ML

Manufacturer/Marketer :

Monokem Labs

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Domril 1mg/ml Syrup

Domril 1mg/ml Syrup is used to treat nausea (feeling sick) and vomiting (being sick) in adults and adolescents 12 years or older. Besides this, it also helps treat indigestion.

Domril 1mg/ml Syrup contains domperidone, which prevents nausea and vomiting by blocking certain receptors (such as dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) in the brain. It also acts as a prokinetic agent, increasing the motility of the upper gastrointestinal tract and helping decrease stomach emptying time.

Take Domril 1mg/ml Syrup as prescribed by your doctor. Symptoms of nausea and vomiting may usually resolve within 3-4 days after taking Domril 1mg/ml Syrup. However, if it does not resolve even after this, stop taking this medicine and contact the doctor. Do not take Domril 1mg/ml Syrup for longer than seven days. The most common side effect of Domril 1mg/ml Syrup is dry mouth. This side effect is temporary and may resolve over time; however, if it persists, contact the doctor.

Do not consume Domril 1mg/ml Syrup if you are hypersensitive to any components present in Domril 1mg/ml Syrup. Before taking the Domril 1mg/ml Syrup, inform your doctor if you suffer from liver or kidney problems. Prolonged intake of Domril 1mg/ml Syrup may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be higher in the elderly (those over 60 years old) or in those taking doses higher than 30 mg daily.

Uses of Domril 1mg/ml Syrup

Domril 1mg/ml Syrup is used to treat nausea and vomiting. The detailed uses of Domril 1mg/ml Syrup are as follows:

  • Nausea Relief: Domril 1mg/ml Syrup is commonly used to relieve nausea and vomiting caused by various conditions, including motion sickness and post-operative effects.
  • Gastroesophageal Reflux Disease (GERD): Domril 1mg/ml Syrup helps manage GERD symptoms by reducing stomach acid and promoting gastric emptying, thereby alleviating discomfort.
  • Functional Dyspepsia: Domril 1mg/ml Syrup can help treat functional dyspepsia, providing relief from bloating, early satiety, and stomach discomfort.
  • Gastroparesis: For patients with delayed gastric emptying (gastroparesis), Domril 1mg/ml Syrup can help stimulate gastric motility, thereby improving symptoms of indigestion and fullness.

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Directions for Use

  • Domril 1mg/ml Syrup can be taken with or without food, or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Domril 1mg/ml Syrup as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Domril 1mg/ml Syrup relieves nausea and vomiting caused by various conditions or medications.
  • Promotes faster gastric emptying by increasing the movement of the stomach and intestines.
  • Helps reduce fullness, bloating, and post-meal discomfort.
  • Improves digestion and prevents feelings of heaviness or indigestion.
  • Useful in managing symptoms of gastroparesis (delayed stomach emptying).
  • Helps relieve nausea associated with migraine and other treatments.
  • Improves overall digestive comfort and gastrointestinal motility.

How Domril 1mg/ml Syrup Works

Domril 1mg/ml Syrup contains domperidone, which prevents nausea and vomiting by blocking certain receptors (such as dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone - CTZ) in the brain. It also acts as a prokinetic agent, increasing motility of the upper gastrointestinal tract and helping decrease stomach emptying time.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Domril 1mg/ml Syrup

Do not take more than the prescribed dose of Domril 1mg/ml Syrup as it may cause an overdose. The symptoms of overdose include uncontrolled movements, which include unusual eye movements, sleepiness, confusion, abnormal posture (such as a twisted neck) or unusual movements of the tongue. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not consume Domril 1mg/ml Syrup if you are allergic to any components present in Domril 1mg/ml Syrup.
  • Before taking the Domril 1mg/ml Syrup, contact your doctor if you suffer from liver or kidney problems (kidney function impairment or failure).
  • Prolonged intake of Domril 1mg/ml Syrup may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be higher in the elderly (those over 60 years old) or in those taking doses higher than 30 mg daily.
  • Tell your doctor if you are using anti-fungal medicines and/or if you have heart problems or AIDS/HIV.
  • If you experience heart rhythm disorders like palpitations, trouble breathing, or loss of consciousness after taking the Domril 1mg/ml Syrup, immediately contact your doctor.
  • Domperidone is not usually recommended in pregnancy and breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine.
  • Adolescents (children aged 12-18 years) who weigh less than 35 kg should not be given Domril 1mg/ml Syrup.

Diet & Lifestyle Advise

  • Eat a healthy low-fat diet, especially in small portions, as it will be easy to digest. Avoid eating overly sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like vomiting at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off.
  • Include more cool beverages with your food, such as clear soups, flavoured gelatin, and carbonated beverages. Also, when drinking with a straw, sip slowly to avoid swallowing air, which can lead to gas or acidity.
  • Drink after, or any other liquid, at least 30 minutes after eating. After eating food, lie down for at least after 2 hours.
  • If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else cook food or use prepared food from the freezer.
  • Avoid caffeine-containing beverages (coffee, tea), spicy/deep-fried/processed foods, carbonated drinks, and acidic foods like citrus fruits/vegetables (tomatoes).

Habit Forming

No

Therapeutic Class

ANTIEMETICS

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Alcohol

Unsafe

Drinking alcohol with Domril 1mg/ml Syrup may cause sleepiness, or an irregular heartbeat.

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Pregnancy

Unsafe

Domril 1mg/ml Syrup is not usually recommended in pregnancy. However, inform your doctor if you are pregnant or planning for pregnancy before taking Domril 1mg/ml Syrup.

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Breast Feeding

Unsafe

Domril 1mg/ml Syrup is not usually recommended when breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine.

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Driving

Safe if prescribed

Domril 1mg/ml Syrup has no effect on your ability to drive or operate machinery.

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Liver

Caution

Domril 1mg/ml Syrup should be taken with precaution in patients with liver disease. Your doctor will weigh the benefits and potential risks before prescribing them.

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Kidney

Caution

Domril 1mg/ml Syrup should be taken with caution in patients with kidney problems. Your doctor will adjust your dose based on the severity of your condition.

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Children

Unsafe

Domril 1mg/ml Syrup should not be given to adolescents younger than 12 years of age or who are less than 35 kg in weight.

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Heart

Inform your doctor if you have heart disease before using Domril 1mg/ml Syrup. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Caution

Domril 1mg/ml Syrup should be given with caution in geriatrics due to increased risk of side effects. If you have any concerns about using Domril 1mg/ml Syrup, please consult a doctor.

FAQs

Domril 1mg/ml Syrup is used to treat nausea (feeling sick) and vomiting (being sick). Besides this, it also helps in the treatment of indigestion.

Domril 1mg/ml Syrup contains domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone - CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

If you are intolerant to sugars, please inform your doctor before starting Domril 1mg/ml Syrup as it contains lactose. So, to avoid any unpleasant side effects, do as your doctor advises.

Yes, Domril 1mg/ml Syrup can cause dry mouth. If you feel excessively thirsty, please increase your fluid intake and perform frequent mouth rinses.

If you miss a dose, take your medicine as soon as you remember. If it is almost time for your next dose, wait until that is due and continue as usual. Do not take a double dose to make up for a forgotten dose.

Domperidone should be used for the shortest time. It is commonly taken for up to a week. Domperidone can produce irregular heartbeats if taken for an extended time or at a high dose.

No, it is a prescribed medication; it should be used only if specified by the doctor.

Domril 1mg/ml Syrup may cause side effects such as dry mouth, headache or diarrhoea. If these side effects persist or worsen, please consult your doctor.

If you have any liver or kidney problems, inform your doctor so an alternative treatment can be recommended.

You are recommended to avoid spicy and oily foods. Limit smoking and alcohol consumption as they may worsen the reflux (stomach acid rising into the oesophagus). Also, avoid carbonated drinks, such as cold drinks and soda, as the carbon dioxide gas they contain may worsen acid reflux. Limit your intake of chocolate and mint. Some painkillers, such as Ibuprofen, may increase acidity and worsen the condition. Thus, avoid using these for prolonged durations.

Take Domril 1mg/ml Syrup only for the duration as prescribed by your doctor. If you get relief from your symptoms, consult your doctor for a follow-up, where your doctor may lower the dose. Long-term use of Domril 1mg/ml Syrup may cause fractures, low vitamin B12 levels and magnesium levels. You need to be cautious about these and continue to monitor your blood levels regularly. If required, your doctor may prescribe supplements to address these deficiencies.

Domril 1mg/ml Syrup is contraindicated in patients with a known hypersensitivity to domperidone or any other inactive ingredients of Domril 1mg/ml Syrup. Patients with underlying liver or kidney disease should use caution.

Yes, the use of Domril 1mg/ml Syrup can cause diarrhoea. If you have diarrhoea, drink plenty of water or other fluids. Avoid consuming fatty or fried foods with Domril 1mg/ml Syrup. If diarrhoea persists and you notice any signs of dehydration, such as decreased urination with dark-coloured, strong-smelling urine.

Store Domril 1mg/ml Syrup at room temperature in a cool and dry place. Protect from direct light and moisture. Keep it out of reach of children.

Yes, Domril 1mg/ml Syrup is safe if used as advised by the doctor. Follow your doctor’s instructions.

It is best to take Domril 1mg/ml Syrup before food. Take it the 15 to 30 minutes before a meal or snack or take it as advised by your doctor.

Take Domril 1mg/ml Syrup as advised by your doctor. Swallow it as whole with a glass of water. Do not crush, chew or break it.

You are recommended to take your doctor’s advice before taking Domril 1mg/ml Syrup if you are pregnant or breastfeeding.

Country of origin

India
Other Info - DOMR162

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Nov 18, 2025 | 7:34 AM IST

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Reference

  1. https://www.nhs.uk/medicines/domperidone/
  2. https://www.medicines.org.uk/emc/files/pil.556.pdf
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