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compositionComposition:DOMPERIDONE-10MG
prescriptionPrescription Medicine
Domifit Drops 30ml

Domifit Drops is used to treat vomiting (being sick) in infants and children. Besides this, it also helps treat indigestion. It contains domperidone, which is a dopamine antagonist. It works by blocking receptors for dopamine and serotonin, which stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) in the brain. It increases the motility of the upper gastrointestinal tract and helps decrease gastric emptying time.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DOMPERIDONE-10MG

Manufacturer/Marketer :

Synthiko Formulations & Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Domifit Drops

Domifit Drops is an antiemetic medicine. It is used to treat vomiting (being sick) in infants and children. Besides this, it also helps treat indigestion. In children, vomiting is a symptom of milk intolerance or food allergy.

Domifit Drops contains domperidone, which is a dopamine antagonist. It works by blocking receptors for dopamine and serotonin, which stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) in the brain. It increases the motility of the upper gastrointestinal tract and helps decrease gastric emptying time.

Domifit Drops causes dry mouth as a side effect in your child. If this side effect worsens, please consult your paediatrician. Domifit Drops should be given as advised by your doctor. Symptoms of nausea and vomiting may usually resolve within 3-4 days after taking Domifit Drops. However, if it does not resolve even after this, stop giving this medicine to your child and contact the paediatrician.

Domifit Drops is intended for paediatric use only. Avoid giving Domifit Drops to your child if she/he is allergic to any of the components present in the formulation. Keep your doctor informed about your child’s health condition, including his current medications and medical history, to rule out any side effects/interactions. Before administration, inform your child’s doctor of any liver or kidney disease.

Uses of Domifit Drops

Domifit Drops is used to treat vomiting. The detailed uses of Domifit Drops are as follows:

  • Nausea Relief: Domifit Drops helps alleviate nausea and vomiting in infants, making it easier for them to settle after feeding.
  • Digestive Aid: Domifit Drops supports healthy digestion by reducing gut discomfort, which can be beneficial for babies experiencing colic or gas.
  • Motion Sickness: Domifit Drops can be used to prevent or treat motion sickness in young children during travel.

Key Benefits

  • Domifit Drops helps relieve nausea and vomiting in infants and children.
  • Promotes faster stomach emptying and improves digestion.
  • Reduces symptoms of fullness, bloating, and discomfort after feeding.
  • Helps in managing gastroesophageal reflux (regurgitation) in babies.
  • Improves feeding tolerance in infants with digestive difficulties.
  • Helps prevent vomiting caused by infections or medication side effects.
  • Provides quick and gentle relief suitable for paediatric use.
  • Liquid form allows accurate dosing and easy administration for children.
Side effects of Domifit Drops 30ml
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

Directions for Use

  • Domifit Drops should be administered 15 to 30 minutes before meals, or as directed by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Administer the prescribed dose to the child using the measuring cup/dosing syringe/dropper.
  • Shake well before use.

How Domifit Drops Works

Domifit Drops contains domperidone which is a dopamine antagonist. It works by blocking certain receptors like dopamine and serotonin which stimulate the vomiting centre (chemoreceptor trigger zone - CTZ) located in the brain. It increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.
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Alcohol

Not applicable

-

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Pregnancy

Not applicable

-

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Breast Feeding

Not applicable

-

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Driving

Not applicable

-

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Liver

Caution

Please consult your doctor if your child has a liver impairment or if you have any concerns regarding this.

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Kidney

Caution

Please consult your doctor if your child has a kidney impairment or if you have any concerns regarding this.

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Children

Safe if prescribed

Domifit Drops is safe for children above if prescribed by the doctor. The dose of the medicine will be decided by your paediatrician. Do not give your child more than the recommended dose.

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Heart

Caution

Domifit Drops may increase the risk of heart problems. Therefore, please inform your doctor if your child have any heart-related problems before using Domifit Drops.

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Geriatrics

Not applicable

Domifit Drops is for paediatric patients only.

What if I have taken an overdose of Domifit Drops

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Domifit Drops may include difficulty in speaking, disorientation, dizziness, fainting, irregular heartbeat, light-headedness, and loss of balance or muscle control. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Diet & Lifestyle Advise

  • The child’s immune system is affected by stress and raises the risk of being sick. Hence try progressive muscle relaxation techniques to relieve stress.
  • Sleeping for 7-9 hours each night can make your child stay fit and safe.
  • Certain food items are known to cause vomiting in your child.
  • Make your child drink more fluids to avoid dehydration.

Have a query?

How Soon It Starts Working

  • The time required for Domifit Drops to start to work: Domifit Drops ideally shows its action within 30 to 60 minutes after administration.
  • The time for which the effects of Domifit Drops last: The effect of Domifit Drops lasts for 6 hours.

What if you forget to take Domifit Drops

If you miss administering a dose to your child, give it as soon as you remember. If it's almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give two doses at once.

Storage

• Store in a cool and dry place away from sunlight.• Keep Domifit Drops out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Avoid giving Domifit Drops to your child if she/he is allergic to any of the components present in the formulation.
  • Keep your doctor informed about your child’s health condition, including his current medications and medical history, to rule out any side effects/interactions.
  • Before administration, inform your child’s doctor of any liver or kidney disease.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Domifit Drops interacts with antibiotics (azithromycin, erythromycin), antifungals (ketoconazole), and antiviral/anti-HIV drugs (ritonavir).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor before administering Domifit Drops if your child has any history of kidney or liver disease.

DomperidoneBepridil
Severe
DomperidoneCitalopram
Severe

Drug-Drug Interactions

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DomperidoneBepridil
Severe
How does the drug interact with Domifit Drops 30ml:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Domifit Drops 30ml and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneCitalopram
Severe
How does the drug interact with Domifit Drops 30ml:
Coadministration of Domifit Drops 30ml with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Domifit Drops 30ml and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with Domifit Drops 30ml:
Coadministration of Domifit Drops 30ml with Nefazodone can increase the blood levels of Domifit Drops 30ml.

How to manage the interaction:
There may be a possibility of interaction between Domifit Drops 30ml and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneToremifene
Severe
How does the drug interact with Domifit Drops 30ml:
Coadministration of Domifit Drops 30ml with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Domifit Drops 30ml and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneRitonavir
Severe
How does the drug interact with Domifit Drops 30ml:
Coadministration of Domifit Drops 30ml with Ritonavir can increase the blood levels of Domifit Drops 30ml.

How to manage the interaction:
There may be a possibility of interaction between Domifit Drops 30ml and Ritonavir, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneClarithromycin
Severe
How does the drug interact with Domifit Drops 30ml:
Coadministration of Domifit Drops 30ml with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Domifit Drops 30ml and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
DomperidoneCisapride
Severe
How does the drug interact with Domifit Drops 30ml:
Coadministration of Domifit Drops 30ml with Cisapride can increase the blood levels of Domifit Drops 30ml.

How to manage the interaction:
There may be a possibility of interaction between Domifit Drops 30ml and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with Domifit Drops 30ml:
Coadministration of Domifit Drops 30ml with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Domifit Drops 30ml and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneKetoconazole
Severe
How does the drug interact with Domifit Drops 30ml:
Coadministration of Domifit Drops 30ml with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Domifit Drops 30ml and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMizolastine
Severe
How does the drug interact with Domifit Drops 30ml:
Combining Mizolastine with Domifit Drops 30ml can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although taking Domifit Drops 30ml and Mizolastine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIEMETICS]

FAQs

Domifit Drops is used to treat vomiting.

Domifit Drops contains domperidone, which is a dopamine antagonist. It works by blocking receptors for dopamine and serotonin, which stimulate the vomiting centre (chemoreceptor trigger zone - CTZ) in the brain.

If your child feels better, please consult your paediatrician before you stop giving Domifit Drops to your child.

Disclaimer

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

  • Dr Aneela Siddabathuni

    MPharma., PhD

Last Updated

Doctor imageWe provide you with authentic, trustworthy and relevant information

Country of origin

India

Manufacturer/Marketer address

23, Vaibhav Industrial Estate. , Opp. ONIDA House, Mahakali Caves Road. , Andheri (E), Mumbai -400 093.
Other Info - DOM0179
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