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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Divalex OD 1000 Tablet is used to treat epilepsy (seizures/fits). It can be used alone or in combination with other medications to treat complex partial seizures that occur alone or alongside other types of seizures. It contains Divalproex sodium, which decreases the brain's excessive and abnormal nerve activity, thereby helping to control seizures. In some cases, it may cause common side effects such as drowsiness, dizziness, and nausea. Before taking this medicine, you should inform your doctor if you are allergic to any of its components, if you are pregnant/breastfeeding, and about all the medications you are taking, as well as any pre-existing medical conditions.

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Manufacturer/Marketer :

Crescent Formulations Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Divalex OD 1000 Tablet

Divalex OD 1000 Tablet belongs to a group of medicines called anticonvulsants or antiepileptics, used to treat epilepsy (seizures/fits). It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures.

The name Divalex OD 1000 Tablet contains 'Divalproex sodium,' which works by increasing the levels of a natural brain chemical called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, Divalex OD 1000 Tablet helps control seizures.

Take Divalex OD 1000 Tablet with or without food. You are advised to take Divalex OD 1000 Tablet as prescribed by your doctor, depending on your medical condition. In some cases, you may experience certain common side effects, such as drowsiness, dizziness, nausea, back pain, increased appetite, constipation, diarrhoea, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you are allergic to any of its contents, have significant liver disease or dysfunction, or have urea cycle disorders. Do not stop taking Divalex OD 1000 Tablet without consulting your doctor, as this may worsen seizures. Avoid taking Divalex OD 1000 Tablet if you are pregnant, as it may cause severe birth defects. Consult your doctor before using Divalex OD 1000 Tablet if you are breastfeeding. Divalex OD 1000 Tablet should be given to children only if prescribed by your doctor. Avoid driving or operating machinery, as Divalex OD 1000 Tablet may cause drowsiness and dizziness. Avoid consuming alcohol along with Divalex OD 1000 Tablet , as it could lead to increased dizziness.

Uses of Divalex OD 1000 Tablet

Divalex OD 1000 Tablet is used in the treatment of epilepsy (seizures). The detailed uses of Divalex OD 1000 Tablet are as follows:<br/>• It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures.<br/>• It may also be used alone or with other medications to treat both simple and complex absence seizures (which cause a brief loss and return of consciousness for a few seconds).<br/>

Directions for Use

  • Divalex OD 1000 Tablet can be taken with or without food, or as advised by the doctor.
  • Shake the bottle well before each use.
  • Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided with the pack.
  • Replace the bottle cap tightly after each use.
  • Avoid using regular household spoons, as they may not accurately measure the dose.
  • Your doctor may adjust the dose and frequency of this medication based on your medical condition.

Medicinal Benefits

Divalex OD 1000 Tablet belongs to a group of medicines called anticonvulsants or antiepileptics, primarily used to treat epilepsy (seizures or fits). It increases the levels of a natural chemical (GABA) in the brain, which helps reduce excessive and abnormal nerve activity in the brain, thereby helping to control seizures. Divalex OD 1000 Tablet is used alone or in combination with other medications to treat complex partial seizures, whether they occur alone or alongside other types of seizures.

How Divalex OD 1000 Tablet Works

Divalex OD 1000 Tablet contains 'Divalproex sodium,' which works by increasing the levels of a natural chemical in the brain called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, Divalex OD 1000 Tablet helps control seizures.

Storage

• Store in a cool and dry place away from sunlight.• Keep Divalex OD 1000 Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Divalex OD 1000 Tablet
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Eat eggs for zinc and other nutrients that support healthy vision.
  • Consume blueberries as antioxidants to combat eye strain.
  • Include broccoli in your diet for diverse eye-boosting nutrients.
  • Eat sweet potatoes as a natural source of vitamin A.
  • Snack on almonds for vitamin E and eye protection.
  • Add tomatoes to your diet for lycopene and vision protection.
  • Perform exercises that improve binocular vision, such as dot-to-dot cards, coloring within lines, and Brock string tests.
  • Wear an eye patch and perform tasks like playing games and solving puzzles.
  • Patching and eye exercises can improve symptoms.
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Divalex OD 1000 Tablet

Do not take more than the prescribed dose of Divalex OD 1000 Tablet , as it may lead to an overdose. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you suspect you have taken an overdose or notice any of these symptoms, please consult a doctor immediately.

Drug Warnings

Do not take Divalex OD 1000 Tablet if you are allergic to any of its contents, have significant liver disease or dysfunction, or have urea cycle disorders. Inform your doctor before taking Divalex OD 1000 Tablet if you have pancreatitis, blood problems, or multi-organ hypersensitivity. Consult your doctor immediately if you experience suicidal tendencies while taking Divalex OD 1000 Tablet . Divalex OD 1000 Tablet may cause thrombocytopenia (low blood platelets), hyperammonemia (high levels of ammonia in the blood), hypothermia (low body temperature), and liver problems. Please do not stop taking Divalex OD 1000 Tablet without consulting your doctor to avoid worsening of seizures. Do not take Divalex OD 1000 Tablet if you are pregnant, as it could cause serious birth defects. If you are of childbearing age, use effective contraception while taking Divalex OD 1000 Tablet . Consult your doctor before taking Divalex OD 1000 Tablet if you are breastfeeding. Divalex OD 1000 Tablet should be given to children only if prescribed by your doctor. Avoid driving or operating machinery, as Divalex OD 1000 Tablet may cause drowsiness and dizziness. Avoid consuming alcohol along with Divalex OD 1000 Tablet , as it could lead to increased drowsiness and dizziness.

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical
How does the drug interact with Divalex OD 1000 Tablet:
Coadministration of Glycerol phenylbutyrate and Divalex OD 1000 Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Glycerol phenylbutyrate and Divalex OD 1000 Tablet together is generally avoided as it can lead to an interaction, it can be taken when your doctor advises. If you experience any symptoms like sudden dizziness, headaches, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Divalex OD 1000 Tablet:
Coadministration of Ertapenem with Divalex OD 1000 Tablet may reduce the blood levels of Divalex OD 1000 Tablet and increase the risk of developing seizures.

How to manage the interaction:
Although there is a possible interaction, ertapenem can be taken with Divalex OD 1000 Tablet if prescribed by the doctor. Consult the doctor if you experience loss of seizure control or changes in behaviour. Do not stop using any medications without talking to your doctor.
DivalproexLomitapide
Severe
How does the drug interact with Divalex OD 1000 Tablet:
Co-administration of Divalex OD 1000 Tablet and Lomitapide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Divalex OD 1000 Tablet and lomitapide can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like fever, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without the doctor's advice.
DivalproexVorinostat
Severe
How does the drug interact with Divalex OD 1000 Tablet:
Coadministration of Divalex OD 1000 Tablet and Vorinostat can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Divalex OD 1000 Tablet and Vorinostat, you can take these medicines together if prescribed by your doctor. If you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Divalex OD 1000 Tablet:
Coadministration of Divalex OD 1000 Tablet and Lamotrigine can increase the risk and severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Divalex OD 1000 Tablet and Lamotrigine, you can take these medicines together if prescribed by your doctor. However, contact your doctor if you experience restlessness, rash, or muscle weakness. Do not stop using any medications without a doctor's advice.
DivalproexSodium oxybate
Severe
How does the drug interact with Divalex OD 1000 Tablet:
Co-administration of Sodium oxybate and Divalex OD 1000 Tablet can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Sodium oxybate and Divalex OD 1000 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like dizziness, sweating, palpitations, and shortness of breath, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexSodium phenylbutyrate
Severe
How does the drug interact with Divalex OD 1000 Tablet:
Co-administration of Sodium phenylbutyrate and Divalex OD 1000 Tablet can increase ammonia levels in the blood and is generally not recommended for patients with urea cycle disorders.

How to manage the interaction:
Co-administration of Divalex OD 1000 Tablet with Sodium phenylbutyrate can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Divalex OD 1000 Tablet:
Co-administration of Divalex OD 1000 Tablet and Ketamine can increase the risk of side effects.

How to manage the interaction:
Co-administration of Divalex OD 1000 Tablet and Ketamine can lead to an interaction, it can be taken if advised by your doctor. If you have any symptoms such as dizziness, drowsiness, shortness of breath, or impairment in thinking and motor coordination, make sure to contact your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Divalex OD 1000 Tablet:
Co-administration of Divalex OD 1000 Tablet and Meropenem can reduce the blood levels of Divalex OD 1000 Tablet sodium.

How to manage the interaction:
Co-administration of Divalex OD 1000 Tablet with Meropenem can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without a doctor's advice.
DivalproexBexarotene
Severe
How does the drug interact with Divalex OD 1000 Tablet:
Co-administration of Divalex OD 1000 Tablet and Bexarotene can increase the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
Co-administration of Divalex OD 1000 Tablet and Bexarotene can lead to an interaction, but it can be taken when advised by your doctor. However, if you experience any symptoms like nausea, vomiting, or stomach cramps, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for energy generation of energy.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps maintain weight and improve overall health.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try to reduce or avoid them.
  • Please pay attention to your overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Divalex OD 1000 Tablet , as it may cause increased drowsiness and dizziness.

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Pregnancy

Unsafe

Divalex OD 1000 Tablet belongs to pregnancy category D. Avoid taking Divalex OD 1000 Tablet if you are pregnant, as it could lead to serious birth defects. Consult your doctor for further advice.

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Breast Feeding

Caution

Divalex OD 1000 Tablet may pass into breastmilk. Consult your doctor before taking Divalex OD 1000 Tablet if you are breastfeeding.

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Driving

Unsafe

Divalex OD 1000 Tablet causes drowsiness and dizziness. Therefore, do not drive or operate machinery until you are mentally alert.

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Liver

Unsafe

Divalex OD 1000 Tablet should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Divalex OD 1000 Tablet should be given to children only if prescribed by a doctor.

Have a query?

FAQs

Divalex OD 1000 Tablet belongs to a group of medicines called anticonvulsants or antiepileptics, used to treat epilepsy (seizures/fits). It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures.

Divalex OD 1000 Tablet contains 'Divalproex sodium,' which works by increasing the levels of a natural chemical in the brain called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, Divalex OD 1000 Tablet helps control seizures.

Do not discontinue Divalex OD 1000 Tablet without consulting your doctor. To treat your condition effectively, continue taking Divalex OD 1000 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Divalex OD 1000 Tablet , your doctor will reduce the dose gradually to avoid worsening of seizures.

Divalex OD 1000 Tablet may cause weight gain due to increased appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective method of contraception during the treatment with Divalex OD 1000 Tablet . Avoid getting pregnant while taking Divalex OD 1000 Tablet as it could lead to severe birth defects. Do not stop taking Divalex OD 1000 Tablet and consult your doctor immediately if you become pregnant.

Divalex OD 1000 Tablet may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking Divalex OD 1000 Tablet .

Topiramate (an anticonvulsant) should not be taken along with Divalex OD 1000 Tablet as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature), and liver problems.

It is crucial to consult with your doctor before discontinuing Divalex OD 1000 Tablet . Abruptly stopping this medication can lead to severe consequences, mainly if it's prescribed to treat conditions like epilepsy.

Divalex OD 1000 Tablet can indeed make you sleepy. This is a common side effect of the medication. If you're experiencing excessive drowsiness, please consult your doctor.

Yes, Divalex OD 1000 Tablet can cause hair loss as a side effect. While this isn't a common side effect, it can occur in some people. If you notice significant hair loss while taking Divalex OD 1000 Tablet , it's essential to consult with your doctor.

Yes, Divalex OD 1000 Tablet can potentially damage your liver. While this is a rare side effect, being aware of the risk is essential. Signs of liver damage may include yellowing of the skin or eyes or jaundice, dark urine, abdominal pain, light-coloured stools, nausea and vomiting. If you experience any of these symptoms while taking Divalex OD 1000 Tablet , seeking medical attention is crucial.

Avoid consumption of alcohol while taking Divalex OD 1000 Tablet , as it may cause increased drowsiness and dizziness.

If you experience abdominal pain, nausea, and anorexia while taking Divalex OD 1000 Tablet , it's essential to contact your doctor immediately. These symptoms can be signs of a severe side effect, such as liver damage.

An overdose of Divalex OD 1000 Tablet can be a severe medical emergency. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you or someone you know has taken an overdose of Divalex OD 1000 Tablet , please seek immediate medical attention.

The common side effects of Divalex OD 1000 Tablet include drowsiness, dizziness, nausea, back pain, increased appetite, constipation, diarrhoea, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

INDIA

Manufacturer/Marketer address

SCO-58, 59, Sector-17D Chandigarh-160017
Other Info - DIV0034

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