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Diprovate Plus ES Ointment 20 gm is used to treat eczema and psoriasis. It works by increasing the amount of moisture in the skin and blocking the production of chemical messengers that make the affected area red, swollen and itchy. In some cases, this medicine may cause side effects such as itching, dryness, and burning sensation at the application site. It is for external use only.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

BETAMETHASONE-0.05%W/W+SALICYLIC ACID-6%W/W+ZINC OXIDE-0.5%W/W

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Topical

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Diprovate Plus ES Ointment 20 gm

Diprovate Plus ES Ointment 20 gm is a topical medication prescribed to treat stubborn, scaly skin conditions such as psoriasis and chronic eczema. Its primary medical purpose is to reduce swelling, clear away thick scales, and protect irritated skin so it can heal. By targeting both the inflammation and the rough outer layers of the skin, this ointment helps restore a smoother texture.

To get the best results, you must apply Diprovate Plus ES Ointment 20 gm consistently and exactly as directed by your healthcare provider, usually once or twice daily. Ensure your skin is completely clean and dry before applying a thin layer of the medication. Along with using this ointment, adopting a gentle skincare routine and avoiding known skin irritants can significantly improve your treatment outcomes.

While Diprovate Plus ES Ointment 20 gm is highly effective, it can occasionally cause localised side effects such as mild burning, irritation, or dryness at the application site. If you notice severe skin thinning, changes in skin colour, or signs of a skin infection, you should stop applying it and consult your doctor immediately. Your pharmacist or doctor can help you manage these side effects safely.

Talk to your doctor or pharmacist before using this medicine if you have a history of skin infections, thin skin, or poor blood circulation. Do not use this if you have an active, untreated skin infection, such as chickenpox, herpes, or a fungal infection, as the steroid component could make it worse. It is also not suitable for individuals with a known allergy to any of its ingredients.

Using other topical medications on the same area may cause unwanted interactions or increase the risk of skin irritation. Speak with your doctor or pharmacist if you are pregnant, breastfeeding, or planning this treatment for an elderly family member, as special precautions may be necessary. Always share a complete list of your current medications with your healthcare provider before starting your treatment.

Uses of Diprovate Plus ES Ointment 20 gm

Diprovate Plus ES Ointment 20 gm is used to treat stubborn, scaly skin conditions such as psoriasis and chronic eczema. The detailed uses of Diprovate Plus ES Ointment 20 gm are as follows:

  • Psoriasis: Diprovate Plus ES Ointment 20 gm helps reduce the buildup of thick, red, scaly plaques on the skin, calming localised inflammation and encouraging the shedding of dead skin cells.
  • Chronic Eczema: This medication relieves intense itching and irritation while softening the rough, thickened skin patches caused by long-term scratching.
  • Hyperkeratosis: It effectively softens and breaks down excessively thick or hard outer layers of skin, allowing the healing ingredients to work more efficiently.

Key Benefits

Diprovate Plus ES Ointment 20 gm provides effective relief from the symptoms of chronic skin conditions by reducing inflammation, soothing irritation, and promoting healthier skin. With regular use, it helps relieve discomfort, improve skin texture, and support the healing process.

  • Relieves Itching, Redness, and Swelling: By calming inflammation and soothing the skin, this medicine helps reduce itchiness, redness, and swelling, allowing you to sleep better and carry out your daily activities more comfortably.
  • Helps Remove Dry, Scaly Skin: This medicine helps loosen and shed stubborn scales and dry patches, leaving the skin smoother and improving its overall texture.
  • Promotes Skin Healing: By supporting the skin's natural healing process, this medicine helps restore a healthier appearance and reduces the risk of painful cracking or splitting caused by excessive dryness.

Directions for Use

  • It is advised to use Diprovate Plus ES Ointment 20 gm two times daily or as advised by your doctor.
  • Apply a thin layer with clean and dry hands on the skin and affected areas. You can also apply it with a piece of clean cotton wool or a gauze swab. Gently rub the medicine into the skin.
  • Wash your hands before and after applying Diprovate Plus ES Ointment 20 gm. Diprovate Plus ES Ointment 20 gm is for topical (for skin use) only. If it gets into your eyes, nose or mouth, rinse with cold water.

How Diprovate Plus ES Ointment 20 gm Works

Diprovate Plus ES Ointment 20 gm works through the coordinated actions of its active ingredients to treat dry, inflamed, and scaly skin conditions. Betamethasone is a strong topical corticosteroid. It works deep within the skin cells to block the chemical messengers that cause swelling, redness, and itching, effectively calming the local immune response. Salicylic acid acts as a keratolytic agent. It softens and breaks down keratin, the protein that binds thick, scaly skin cells together, helping the dead skin peel away gently and allowing the steroid to penetrate deeper. Zinc oxide is a mild skin protectant and astringent. It forms a physical barrier on the skin's surface to soothe raw, irritated areas, reduce moisture loss, and protect the healing skin from external irritants.
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Alcohol

Safe if prescribed

No interaction found/ established. Please consult your doctor before using Diprovate Plus ES Ointment 20 gm.

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Pregnancy

Caution

Topical usage of corticosteroids (Betamethasone) during pregnancy may affect the developing baby. It is advised to consult your doctor if you plan to conceive or already pregnant before starting Diprovate Plus ES Ointment 20 gm.

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Breast Feeding

Caution

There are limited studies on how Diprovate Plus ES Ointment 20 gm affects breastfed infants. Please consult your doctor before using Diprovate Plus ES Ointment 20 gm if you are breastfeeding. If you need to apply the cream/ointment on your breasts, don't do this shortly before giving a feed.

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Driving

Safe if prescribed

Diprovate Plus ES Ointment 20 gm has no or negligible influence on the ability to drive or use machines.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Diprovate Plus ES Ointment 20 gm.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Diprovate Plus ES Ointment 20 gm.

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Children

Caution

Diprovate Plus ES Ointment 20 gm is not recommended for children below 12 years of age since it contains a steroid, Betamethasone. If it is prescribed for children, your doctor may ask you to stop the course within five days.

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Heart

Consult your doctor

Inform your doctor if you have any existing heart disease. Your doctor will prescribe this medicine only if the potential benefits outweigh the risks.

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Geriatrics

Caution

Diprovate Plus ES Ointment 20 gm should be used with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Diprovate Plus ES Ointment 20 gm.

What if I have taken an overdose of Diprovate Plus ES Ointment 20 gm

This medicine is only meant for use on the skin. If anyone accidentally swallows the ointment, or if you apply much more than recommended over a long period, seek immediate medical attention.

Diet & Lifestyle Advise

  • Avoid taking hot baths or showers, as hot water strips natural oils from your skin; use lukewarm water instead.
  • Apply a gentle, fragrance-free moisturiser immediately after bathing to lock moisture into your skin.
  • Wear loose-fitting, soft clothing made of natural fibres like cotton to minimise friction and irritation on treated areas.
  • Keep a daily journal to identify and avoid personal skin triggers, such as specific soaps, detergents, environmental factors, or stress.
  • Stay well-hydrated throughout the day by drinking plenty of water to support your skin's natural moisture barrier.
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Have a query?

How Soon It Starts Working

The time required for Diprovate Plus ES Ointment 20 gm to start to work: Diprovate Plus ES Ointment 20 gm ideally shows its action within 1 to 2 weeks of consistent use. The time for which the effects of Diprovate Plus ES Ointment 20 gm last: The duration of action for Diprovate Plus ES Ointment 20 gm is clinically unknown.

What if you forget to take Diprovate Plus ES Ointment 20 gm

If you forget to apply Diprovate Plus ES Ointment 20 gm, use it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and return to your regular routine. Do not apply a double amount to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Always inspect the tube before use; do not use the ointment if the seal is broken, the tube is damaged, or if the product has changed colour or separated.
  • Keep the medication away from your eyes, nose, mouth, and inside of your ears; rinse thoroughly with cool water if accidental contact occurs.
  • Do not apply this ointment to open wounds, deep cuts, scraped skin, or active skin infections.
  • Avoid using this product on sensitive areas like your face, underarms, or groin unless your doctor explicitly instructs you to do so.
  • Limit the duration of your treatment to the timeframe recommended by your doctor, as prolonged use can cause permanent skin thinning.

verifiedApollotooltip
  • Other topical corticosteroids: Using other steroid creams or ointments at the same time can increase the risk of skin thinning and systemic absorption.
  • Medicated cleansers or peeling agents: Combining this with harsh soaps, salicylic acid washes, or abrasive skin products can lead to severe skin irritation and dryness.

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verifiedApollotooltip

No clinically significant food interactions are known with Diprovate Plus ES Ointment 20 gm when used as directed.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS DERMATOLOGICALS]

FAQs

Using Diprovate Plus ES Ointment 20 gm for longer than prescribed can increase the risk of side effects. Long-term use may cause skin thinning, stretch marks, changes in skin colour, increased hair growth, and visible blood vessels. If large amounts are absorbed through the skin, especially when used over large areas or under dressings, it may rarely affect your body's natural steroid production, leading to problems such as adrenal suppression or Cushing's syndrome. Use Diprovate Plus ES Ointment 20 gm only for the duration prescribed by your doctor and attend follow-up appointments if long-term treatment is needed.
No. Do not cover the treated area with bandages, plastic wrap, or dressings unless your doctor specifically tells you to. Covering the area increases the absorption of the steroid through the skin, which raises the risk of side effects. Avoid applying Diprovate Plus ES Ointment 20 gm to the eyes, mouth, nose, mucous membranes, open wounds, or large areas of skin unless directed by your doctor. If the medicine accidentally gets into your eyes, nose, or mouth, rinse thoroughly with water.
You should avoid applying Diprovate Plus ES Ointment 20 gm to your face unless your doctor specifically instructs you to do so. The skin on the face is highly sensitive and prone to thinning or discolouration from strong topical steroids. Talk to your doctor for advice on facial skin treatments.
Many patients begin to notice an improvement in itching and skin texture within a few days of consistent use. However, the exact timeline depends on the severity of your skin condition. Talk to your doctor if you do not see any improvement after two weeks of treatment.
This medication should only be used during pregnancy if your doctor determines that the benefits outweigh the potential risks. When prescribed, it is typically used in small amounts for a short duration. Talk to your doctor to evaluate what is safest for you.
If you notice your skin becoming unusually thin, fragile, or showing stretch marks and visible blood vessels, stop using the ointment and contact your healthcare provider. Your doctor may need to adjust your treatment plan or switch you to a milder option.
Children have thinner skin and can absorb larger amounts of the medication, making them more vulnerable to side effects. Therefore, Diprovate Plus ES Ointment 20 gm must only be used in children under strict medical supervision. Talk to your doctor before applying this medication to a child.
While Diprovate Plus ES Ointment 20 gm is highly effective at managing symptoms, clearing scales, and reducing inflammation, it does not cure chronic skin conditions like psoriasis or eczema. It is designed to control flare-ups and maintain smoother skin. Talk to your doctor about long-term management.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Betamethasone Topical Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Salicylic Acid Topical Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Drugs.com Clinical Review Team. Zinc Oxide Topical Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  5. Electronic Medicines Compendium (EMC). Pil.1450 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  6. Malfitan VA Betamethasone dipropionate and salicylic acid lotion for nonscalp dermatoses. Clin Ther. 1989;5(3):290-8Check here
  7. Betamethasone Betamethasone. 1997. [Accessed on 04 Apr. 2019]Check here

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - DIP0030

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