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  3. DIPROEX ER 750MG TABLET

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DIPROEX ER 750MG TABLET, Pack of 10 TABLETS
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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

DIPROEX ER 750MG TABLET is used to treat epilepsy (seizures/fits). It can be used alone or in combination with other medications to treat complex partial seizures that occur alone or alongside other types of seizures. It contains Divalproex sodium, which decreases the brain's excessive and abnormal nerve activity, thereby helping to control seizures. In some cases, it may cause common side effects such as drowsiness, dizziness, and nausea. Before taking this medicine, you should inform your doctor if you are allergic to any of its components, if you are pregnant/breastfeeding, and about all the medications you are taking, as well as any pre-existing medical conditions.

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Composition :

DIVALPROEX SODIUM-750MG

Manufacturer/Marketer :

Unisearch Lab Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About DIPROEX ER 750MG TABLET

DIPROEX ER 750MG TABLET belongs to a group of medicines called anticonvulsants or antiepileptics, used to treat epilepsy (seizures/fits). It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures.

The name DIPROEX ER 750MG TABLET contains 'Divalproex sodium,' which works by increasing the levels of a natural brain chemical called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, DIPROEX ER 750MG TABLET helps control seizures.

Take DIPROEX ER 750MG TABLET with or without food. You are advised to take DIPROEX ER 750MG TABLET as prescribed by your doctor, depending on your medical condition. In some cases, you may experience certain common side effects, such as drowsiness, dizziness, nausea, back pain, increased appetite, constipation, diarrhoea, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you are allergic to any of its contents, have significant liver disease or dysfunction, or have urea cycle disorders. Do not stop taking DIPROEX ER 750MG TABLET without consulting your doctor, as this may worsen seizures. Avoid taking DIPROEX ER 750MG TABLET if you are pregnant, as it may cause severe birth defects. Consult your doctor before using DIPROEX ER 750MG TABLET if you are breastfeeding. DIPROEX ER 750MG TABLET should be given to children only if prescribed by your doctor. Avoid driving or operating machinery, as DIPROEX ER 750MG TABLET may cause drowsiness and dizziness. Avoid consuming alcohol along with DIPROEX ER 750MG TABLET, as it could lead to increased dizziness.

Uses of DIPROEX ER 750MG TABLET

DIPROEX ER 750MG TABLET is used in the treatment of epilepsy (seizures). The detailed uses of DIPROEX ER 750MG TABLET are as follows:

  • Partial seizures: It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures.
  • Simple and complex absence seizures: It may also be used alone or with other medications to treat both simple and complex absence seizures (which cause a brief loss and return of consciousness for a few seconds).

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Directions for Use

  • DIPROEX ER 750MG TABLET can be taken with or without food, or as advised by the doctor.
  • Shake the bottle well before each use.
  • Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided with the pack.
  • Replace the bottle cap tightly after each use.
  • Avoid using regular household spoons, as they may not accurately measure the dose.
  • Your doctor may adjust the dose and frequency of this medication based on your medical condition.

Medicinal Benefits

DIPROEX ER 750MG TABLET belongs to a group of medicines called anticonvulsants or antiepileptics, primarily used to treat epilepsy (seizures or fits). It increases the levels of a natural chemical (GABA) in the brain, which helps reduce excessive and abnormal nerve activity in the brain, thereby helping to control seizures. DIPROEX ER 750MG TABLET is used alone or in combination with other medications to treat complex partial seizures, whether they occur alone or alongside other types of seizures.

How DIPROEX ER 750MG TABLET Works

DIPROEX ER 750MG TABLET contains 'Divalproex sodium,' which works by increasing the levels of a natural chemical in the brain called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, DIPROEX ER 750MG TABLET helps control seizures.

Storage

• Store in a cool and dry place away from sunlight.• Keep DIPROEX ER 750MG TABLET out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Diproex Er 750mg Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
  • Write things in a notebook or on sticky notes.
  • Be physically and mentally active.
  • Maintain social interaction to avoid stress and depression which could contribute to memory loss.
  • Sleep well as inadequate sleep may also cause memory loss.
  • Maintain a healthy diet which includes fruits, vegetables, whole grains, fish and skinless poultry.
  • Avoid alcohol consumption as it may cause confusion and memory loss.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of DIPROEX ER 750MG TABLET

Do not take more than the prescribed dose of DIPROEX ER 750MG TABLET, as it may lead to an overdose. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you suspect you have taken an overdose or notice any of these symptoms, please consult a doctor immediately.

Drug Warnings

Do not take DIPROEX ER 750MG TABLET if you are allergic to any of its contents, have significant liver disease or dysfunction, or have urea cycle disorders. Inform your doctor before taking DIPROEX ER 750MG TABLET if you have pancreatitis, blood problems, or multi-organ hypersensitivity. Consult your doctor immediately if you experience suicidal tendencies while taking DIPROEX ER 750MG TABLET. DIPROEX ER 750MG TABLET may cause thrombocytopenia (low blood platelets), hyperammonemia (high levels of ammonia in the blood), hypothermia (low body temperature), and liver problems. Please do not stop taking DIPROEX ER 750MG TABLET without consulting your doctor to avoid worsening of seizures. Do not take DIPROEX ER 750MG TABLET if you are pregnant, as it could cause serious birth defects. If you are of childbearing age, use effective contraception while taking DIPROEX ER 750MG TABLET. Consult your doctor before taking DIPROEX ER 750MG TABLET if you are breastfeeding. DIPROEX ER 750MG TABLET should be given to children only if prescribed by your doctor. Avoid driving or operating machinery, as DIPROEX ER 750MG TABLET may cause drowsiness and dizziness. Avoid consuming alcohol along with DIPROEX ER 750MG TABLET, as it could lead to increased drowsiness and dizziness.

Drug-Drug Interactions

verifiedApollotooltip
DivalproexGlycerol phenylbutyrate
Critical
DivalproexEsketamine
Severe

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical
How does the drug interact with Diproex Er 750mg Tablet:
Coadministration of Glycerol phenylbutyrate and Diproex Er 750mg Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Glycerol phenylbutyrate and Diproex Er 750mg Tablet together is generally avoided as it can lead to an interaction, it can be taken when your doctor advises. If you experience any symptoms like sudden dizziness, headaches, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DivalproexEsketamine
Severe
How does the drug interact with Diproex Er 750mg Tablet:
Coadministration of Esketamine and Diproex Er 750mg Tablet can increase the side effects of esketamine.

How to manage the interaction:
Although taking Diproex Er 750mg Tablet and Esketamine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any symptoms like drowsiness and impaired motor coordination, consult the doctor immediately. Do not stop using any medications without talking to your doctor.
DivalproexBuprenorphine
Severe
How does the drug interact with Diproex Er 750mg Tablet:
Co-administration of buprenorphine with Diproex Er 750mg Tablet may increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Buprenorphine with Diproex Er 750mg Tablet can result in an interaction, it can be taken when a doctor has advised it. However, if you experience shortness of breath, irregular heart rhythms, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DivalproexLeflunomide
Severe
How does the drug interact with Diproex Er 750mg Tablet:
Co-administration of Diproex Er 750mg Tablet and leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Diproex Er 750mg Tablet and leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
DivalproexKetoconazole
Severe
How does the drug interact with Diproex Er 750mg Tablet:
Coadministration of Ketoconazole and Diproex Er 750mg Tablet may increase the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Diproex Er 750mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain, fatigue, nausea, vomiting, stomach pain, dark urine, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexLamotrigine
Severe
How does the drug interact with Diproex Er 750mg Tablet:
Coadministration of Diproex Er 750mg Tablet and Lamotrigine can increase the risk and severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Diproex Er 750mg Tablet and Lamotrigine, you can take these medicines together if prescribed by your doctor. However, contact your doctor if you experience restlessness, rash, or muscle weakness. Do not stop using any medications without a doctor's advice.
DivalproexMipomersen
Severe
How does the drug interact with Diproex Er 750mg Tablet:
Co-administration of Diproex Er 750mg Tablet and mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Diproex Er 750mg Tablet and mipomersen can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult the doctor immediately. Avoid alcohol consumption, and Do not stop using any medications without a doctor's advice.
DivalproexVorinostat
Severe
How does the drug interact with Diproex Er 750mg Tablet:
Coadministration of Diproex Er 750mg Tablet and Vorinostat can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Diproex Er 750mg Tablet and Vorinostat, you can take these medicines together if prescribed by your doctor. If you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor immediately. Do not discontinue any medications without consulting your doctor.
DivalproexErtapenem
Severe
How does the drug interact with Diproex Er 750mg Tablet:
Coadministration of Ertapenem with Diproex Er 750mg Tablet may reduce the blood levels of Diproex Er 750mg Tablet and increase the risk of developing seizures.

How to manage the interaction:
Although there is a possible interaction, ertapenem can be taken with Diproex Er 750mg Tablet if prescribed by the doctor. Consult the doctor if you experience loss of seizure control or changes in behaviour. Do not stop using any medications without talking to your doctor.
DivalproexMeropenem
Severe
How does the drug interact with Diproex Er 750mg Tablet:
Co-administration of Diproex Er 750mg Tablet and Meropenem can reduce the blood levels of Diproex Er 750mg Tablet sodium.

How to manage the interaction:
Co-administration of Diproex Er 750mg Tablet with Meropenem can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for energy generation of energy.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps maintain weight and improve overall health.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try to reduce or avoid them.
  • Please pay attention to your overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

DIPROEX ER 750MG TABLET Substitute

Substitutes safety advice
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Alcohol

Unsafe

Avoid consumption of alcohol while taking DIPROEX ER 750MG TABLET, as it may cause increased drowsiness and dizziness.

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Pregnancy

Unsafe

DIPROEX ER 750MG TABLET belongs to pregnancy category D. Avoid taking DIPROEX ER 750MG TABLET if you are pregnant, as it could lead to serious birth defects. Consult your doctor for further advice.

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Breast Feeding

Caution

DIPROEX ER 750MG TABLET may pass into breastmilk. Consult your doctor before taking DIPROEX ER 750MG TABLET if you are breastfeeding.

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Driving

Unsafe

DIPROEX ER 750MG TABLET causes drowsiness and dizziness. Therefore, do not drive or operate machinery until you are mentally alert.

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Liver

Unsafe

DIPROEX ER 750MG TABLET should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have liver problems or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

DIPROEX ER 750MG TABLET should be given to children only if prescribed by a doctor.

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Heart

Please inform your doctor if you have heart problems before taking DIPROEX ER 750MG TABLET, as there is limited information available on its safety in such cases.

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Geriatrics

Caution

DIPROEX ER 750MG TABLET can be taken if you're geriatric, but it requires careful monitoring and medical supervision.

FAQs

DIPROEX ER 750MG TABLET belongs to a group of medicines called anticonvulsants or antiepileptics, used to treat epilepsy (seizures/fits). It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures.

DIPROEX ER 750MG TABLET contains 'Divalproex sodium,' which works by increasing the levels of a natural chemical in the brain called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, DIPROEX ER 750MG TABLET helps control seizures.

Do not discontinue DIPROEX ER 750MG TABLET without consulting your doctor. To treat your condition effectively, continue taking DIPROEX ER 750MG TABLET for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking DIPROEX ER 750MG TABLET, your doctor will reduce the dose gradually to avoid worsening of seizures.

DIPROEX ER 750MG TABLET may cause weight gain due to increased appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective method of contraception during the treatment with DIPROEX ER 750MG TABLET. Avoid getting pregnant while taking DIPROEX ER 750MG TABLET as it could lead to severe birth defects. Do not stop taking DIPROEX ER 750MG TABLET and consult your doctor immediately if you become pregnant.

DIPROEX ER 750MG TABLET may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking DIPROEX ER 750MG TABLET.

Topiramate (an anticonvulsant) should not be taken along with DIPROEX ER 750MG TABLET as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature), and liver problems.

It is crucial to consult with your doctor before discontinuing DIPROEX ER 750MG TABLET. Abruptly stopping this medication can lead to severe consequences, mainly if it's prescribed to treat conditions like epilepsy.

DIPROEX ER 750MG TABLET can indeed make you sleepy. This is a common side effect of the medication. If you're experiencing excessive drowsiness, please consult your doctor.

Yes, DIPROEX ER 750MG TABLET can cause hair loss as a side effect. While this isn't a common side effect, it can occur in some people. If you notice significant hair loss while taking DIPROEX ER 750MG TABLET, it's essential to consult with your doctor.

Yes, DIPROEX ER 750MG TABLET can potentially damage your liver. While this is a rare side effect, being aware of the risk is essential. Signs of liver damage may include yellowing of the skin or eyes or jaundice, dark urine, abdominal pain, light-coloured stools, nausea and vomiting. If you experience any of these symptoms while taking DIPROEX ER 750MG TABLET, seeking medical attention is crucial.

Avoid consumption of alcohol while taking DIPROEX ER 750MG TABLET, as it may cause increased drowsiness and dizziness.

If you experience abdominal pain, nausea, and anorexia while taking DIPROEX ER 750MG TABLET, it's essential to contact your doctor immediately. These symptoms can be signs of a severe side effect, such as liver damage.

An overdose of DIPROEX ER 750MG TABLET can be a severe medical emergency. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you or someone you know has taken an overdose of DIPROEX ER 750MG TABLET, please seek immediate medical attention.

The common side effects of DIPROEX ER 750MG TABLET include drowsiness, dizziness, nausea, back pain, increased appetite, constipation, diarrhoea, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

NO:21A, PLS NAGAR, SITE NO:5, PHASE II,,CHINNIYAMPALAYAM POST,Coimbatore,Tamil Nadu,INDIA,641062
Other Info - DIP0038

Disclaimer

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Reference

  1. https://www.intaspharma.com/wp-content/uploads/2018/12/DIVAA.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/018081s056lbl.pdf
  3. https://www.drugs.com/pro/valproic-acid-oral-solution.html
  4. https://medlineplus.gov/druginfo/meds/a682412.html

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