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compositionComposition:PHENYTOIN-125MG
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Prescription Medicine
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Dilantin Oral Suspension is used to treat epilepsy/seizures, and prevent seizures during/after brain surgery or after traumatic brain injury. It contains Phenytoin, which helps prevent neurons from working at a very fast speed, thereby preventing the brain cells from firing together rapidly in an uncontrolled way. As a result, it helps control seizures. In some cases, it may cause certain common side effects such as weakness, drowsiness, dizziness, confusion, restlessness, slurred speech, constipation, loss of coordination, and abnormal eye movement. Before taking this medicine, inform your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

PHENYTOIN-125MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Dilantin Oral Suspension

Dilantin Oral Suspension is an oral antiseizure medicine prescribed to control and prevent certain types of seizures, including tonic-clonic (grand mal) and focal seizures that may involve the temporal lobe. It works by reducing abnormal electrical activity in the brain. Regular treatment can help reduce seizure episodes and support a safer, more stable daily routine.

For Dilantin Oral Suspension to work properly, take it at the same times each day and exactly as prescribed by your doctor. The oral suspension can generally be taken with or without food, but try to take every dose in the same way to keep the amount of medicine in your body consistent. Shake the bottle well before every dose and measure the medicine with an oral syringe or other accurate measuring device. Maintaining regular sleep and avoiding known seizure triggers can also support seizure control.

Common side effects of Dilantin Oral Suspension include dizziness, drowsiness, nausea, and problems with coordination. Long-term use can also cause gum swelling or overgrowth. Contact your doctor promptly if you develop a severe skin rash, unusual bruising, yellowing of the skin or eyes, severe weakness, or significant changes in mood or behavior.

Before starting Dilantin Oral Suspension , tell your doctor if you have liver disease, kidney problems, diabetes, blood disorders, or a history of depression or other mood problems. Do not use this medicine if you have previously had a serious allergic reaction to Dilantin Oral Suspension or certain related medicines, or if you developed a serious liver or blood-related reaction while taking it in the past.

Dilantin Oral Suspension interacts with many medicines because it can affect how other drugs are broken down in the body. It can also interact with alcohol and may cause increased dizziness or drowsiness. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, discuss the benefits and possible risks with your doctor before using this medicine. Tell your doctor about every medicine, supplement, and herbal product you take.

Uses of Dilantin Oral Suspension

Dilantin Oral Suspension is used in the treatment of epilepsy/seizures and trigeminal neuralgia. The detailed uses of Dilantin Oral Suspension are as follows:

  • Tonic-clonic seizures: Dilantin Oral Suspension helps control certain generalized seizures by reducing excessive electrical activity in the brain.
  • Focal (partial) seizures: It helps prevent abnormal electrical activity that starts in one area of the brain and may affect awareness, behavior, or movement.
  • Seizure prevention around brain surgery: Dilantin Oral Suspension may be used in selected patients to prevent or control seizures associated with neurosurgical procedures, according to the doctor's assessment.

Key Benefits

  • Helps control seizures: Reduces abnormal electrical activity in the brain and helps prevent certain types of seizures.
  • Reduces seizure-related risks: Better seizure control may lower the risk of injuries and interruptions to everyday activities.
  • Supports daily life: Regular use may help reduce the disruption caused by repeated seizures and support a more predictable daily routine.
  • Helps maintain seizure control: Taking Dilantin Oral Suspension consistently and attending recommended follow-up appointments are important for keeping seizures under control.
  • Requires careful monitoring: Dilantin Oral Suspension has a narrow therapeutic index, meaning the effective dose and the dose that may cause toxicity are relatively close.
  • Blood tests may be needed: Your doctor may check Dilantin Oral Suspension levels and adjust the dose when necessary to maintain a safe and effective treatment level.
Side effects of Dilantin Oral Suspension 100 ml
  • Uncoordinated muscle movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Here are the steps to manage medication-triggered Nervousness:
  • Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
  • Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
  • Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
  • Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
  • You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Eat a balanced diet rich in anti-inflammatory foods, such as leafy greens, berries, and fatty fish.
  • Avoid consuming excessive processed foods, sugary drinks, and snacks.
  • Drink plenty of water to stay hydrated.
  • Practice stress-reducing techniques, such as yoga or meditation, to help manage stress and promote overall well-being.
  • If you're concerned about skin nodules, consult a dermatologist for personalized advice and treatment options.
  • Wear an eye patch or opaque contact lens or lens applied to glasses to block the vision of one eye to minimize double vision.
  • Use prisms (lenses applied to glasses) to correct double vision due to small misalignments.
  • Try doing some eye exercises such as moving the target towards nose slowly or focussing on a detailed target like thin stick or small text in a magazine.
  • If you feel eye pain, develop bulging eyes, have weakness, headache or double vision, consult a doctor immediately.

Directions for Use

  • Dilantin Oral Suspension can be taken with or without food, as advised by your doctor.
  • Your doctor will determine the dosage and timing of Dilantin Oral Suspension based on your medical condition.
  • Check the label for directions. Shake the bottle well before each use.
  • Take the prescribed dose orally using the measuring cup provided with the package.
  • Avoid using regular household spoons, as they may not accurately measure the dose correctly.

How Dilantin Oral Suspension Works

Always shake the oral suspension bottle thoroughly before each dose to ensure the medicine is mixed evenly. Use a proper medical measuring spoon, syringe, or dosing cup to measure your dose accurately; do not use a regular household spoon as it will not provide the correct measurement. Take Dilantin Oral Suspension exactly as your doctor has prescribed. Do not change your dose or stop taking this medicine suddenly without consulting your doctor, as stopping abruptly can trigger continuous, severe seizures.
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Alcohol

Unsafe

Avoid alcohol consumption while taking Dilantin Oral Suspension , as it may increase/decrease your blood levels of this medication and cause unpleasant side effects.

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Pregnancy

Caution

Do not take Dilantin Oral Suspension if you are pregnant unless prescribed by the doctor. Your doctor will prescribe Dilantin Oral Suspension only if the benefits outweigh the risks. If you become pregnant while taking Dilantin Oral Suspension , then do not stop taking Dilantin Oral Suspension without consulting your doctor.

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Breast Feeding

Caution

Please consult your doctor before taking Dilantin Oral Suspension if you are breastfeeding. Your doctor will decide whether Dilantin Oral Suspension can be given to breastfeeding mothers or not.

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Driving

Unsafe

Dilantin Oral Suspension may cause dizziness and drowsiness. Therefore, avoid driving and operating machinery until you are mentally alert.

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Liver

Caution

Dose adjustment may be needed. Dilantin Oral Suspension should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Dilantin Oral Suspension should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Dilantin Oral Suspension should be given to children only if prescribed by a doctor.

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Heart

Caution

Dilantin Oral Suspension should be used with caution in patients with heart disease. Dose adjustment may be needed in such patients.

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Geriatrics

Consult your doctor

Dilantin Oral Suspension can be used in the elderly, but a lower or less frequent dose may be needed. Consult your doctor if you have any concerns.

What if I have taken an overdose of Dilantin Oral Suspension

In case of an accidental overdose, seek emergency medical attention or call your local poison control center immediately. Symptoms of an overdose may include extreme drowsiness, rapid eye movements, slurred speech, or loss of balance.

Diet & Lifestyle Advise

  • Maintain a regular sleep schedule: Poor sleep can trigger seizures in some people. Aim for consistent sleep and wake times.
  • Support bone health: Long-term Dilantin Oral Suspension use may affect vitamin D and bone health. Eat calcium- and vitamin-D-rich foods and ask your doctor whether you need supplements.
  • Avoid or limit alcohol: Alcohol can increase dizziness and drowsiness and may affect Dilantin Oral Suspension levels or seizure control.
  • Keep your diet consistent: Large or sudden changes in your diet may affect medicine absorption. Tell your doctor before starting a special diet, including a ketogenic diet.
  • Take care with tube feeding: If you receive nutrition through an enteral feeding tube, Dilantin Oral Suspension absorption can be reduced. Your doctor or dietitian may recommend separating tube feeds from the medicine and monitoring Dilantin Oral Suspension levels.
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Have a query?

How Soon It Starts Working

The time required for Dilantin Oral Suspension to start to work: Dilantin Oral Suspension ideally shows its action within 1 to 3 hours after administration. The time for which the effects of Dilantin Oral Suspension last: The effect of Dilantin Oral Suspension lasts for 2 to 3 days.

What if you forget to take Dilantin Oral Suspension

If you miss a dose of Dilantin Oral Suspension , take it as soon as you remember. However, if it is almost time for your next scheduled dose (within 4 hours), skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one. Talk to your doctor if you miss multiple doses.

Storage

• Store Dilantin Oral Suspension oral suspension at room temperature, between 20°C and 25°C (68°F to 77°F). Keep the bottle tightly closed when not in use.

Drug Warnings

  • Shake before every dose: Shake the suspension thoroughly so that each dose contains the correct amount of medicine.
  • Use an accurate measuring device: An oral syringe or supplied dosing device is more accurate than a household spoon.
  • Keep your formulation consistent: Do not switch between different Dilantin Oral Suspension products, brands, or dosage forms without your doctor's advice.
  • Maintain good oral hygiene: Brush gently twice daily, floss regularly, and have routine dental checkups to help reduce gum swelling and overgrowth.
  • Know your medicines: Dilantin Oral Suspension interacts with many prescription and non-prescription medicines. Always provide your doctor and pharmacist with your complete medication list.
  • Carry medical identification: Consider carrying a medical alert card or wearing a medical alert bracelet that states that you take Dilantin Oral Suspension for seizure control.
  • Be careful with driving: Avoid driving or operating machinery until you know how Dilantin Oral Suspension affects your alertness, vision, and coordination.
  • Do not stop suddenly: Even if you have been seizure-free, continue Dilantin Oral Suspension unless your doctor tells you to reduce or stop it gradually.

Drug-Drug Interactions

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  • Hormonal contraceptives: Dilantin Oral Suspension can make birth control pills, patches, implants, and some other hormonal contraceptives less effective. Discuss reliable alternative or additional contraception with your doctor.
  • Other antiseizure medicines: Medicines such as carbamazepine and valproic acid can interact with Dilantin Oral Suspension and may change its blood levels or effects. Close monitoring may be needed.
  • Antifungal medicines: Medicines such as fluconazole can increase Dilantin Oral Suspension levels and the risk of side effects. Your doctor may need to monitor your blood levels and adjust the dose.
  • Certain antibiotics: Medicines such as rifampin can lower Dilantin Oral Suspension levels and may reduce seizure control. Tell your doctor before starting an antibiotic.
  • Blood thinners: Dilantin Oral Suspension can interact with medicines such as warfarin and may alter their effects. Regular monitoring may be required.
  • Antacids: Some antacids containing calcium, magnesium, or aluminum can reduce Dilantin Oral Suspension absorption when taken together. Follow your pharmacist's advice about separating the doses.

Drug-Drug Interactions

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How does the drug interact with Dilantin Oral Suspension 100 ml:
Taking ceritinib with Dilantin Oral Suspension 100 ml may significantly reduce the blood levels and effectiveness of Ceritinib.

How to manage the interaction:
Taking Dilantin Oral Suspension 100 ml with Ceritinib is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dilantin Oral Suspension 100 ml:
Using praziquantel together with Dilantin Oral Suspension 100 ml may significantly reduce the blood levels of praziquantel leading decreased effectiveness.

How to manage the interaction:
Taking Dilantin Oral Suspension 100 ml with Praziquantelcan is not recommended as it cause an interaction, it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
PhenytoinRilpivirine
Critical
How does the drug interact with Dilantin Oral Suspension 100 ml:
Using rilpivirine together with Dilantin Oral Suspension 100 ml may significantly reduce the blood levels of rilpivirine.

How to manage the interaction:
Taking Rilpivirine with Dilantin Oral Suspension 100 ml is not recommended, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dilantin Oral Suspension 100 ml:
Using ranolazine together with Dilantin Oral Suspension 100 ml may significantly reduce the blood levels of ranolazine leading to dreceased effectiveness of ranolazine in treating your condition.

How to manage the interaction:
Taking Dilantin Oral Suspension 100 ml with Ranolazine is not recommended. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PhenytoinVenetoclax
Critical
How does the drug interact with Dilantin Oral Suspension 100 ml:
Using venetoclax together with Dilantin Oral Suspension 100 ml may significantly reduce the blood levels of venetoclax leading to decreased effectiveness of venetoclax in treating in your condition.

How to manage the interaction:
Taking Dilantin Oral Suspension 100 ml with Venetoclax is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
PhenytoinCimetidine
Critical
How does the drug interact with Dilantin Oral Suspension 100 ml:
Using Dilantin Oral Suspension 100 ml together with cimetidine may increase the effects of Dilantin Oral Suspension 100 ml.

How to manage the interaction:
Taking Dilantin Oral Suspension 100 ml with Cimetidine is not recommended, it can be taken if prescribed by the doctor. Contact a doctor, if you experience twitching eye movements, slurred speech, loss of balance, tremors, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dilantin Oral Suspension 100 ml:
Co-administration of Dilantin Oral Suspension 100 ml and Isavuconazole may significantly reduce the blood levels of Isavuconazole, which may make Isavuconazole less effective in treating your condition.

How to manage the interaction:
Taking Isavuconazole with Dilantin Oral Suspension 100 ml is not recommended as it can cause an interaction, consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Dilantin Oral Suspension 100 ml:
Using lurasidone together with Dilantin Oral Suspension 100 ml may significantly decrease the blood levels of lurasidone.

How to manage the interaction:
Using lurasidone with Dilantin Oral Suspension 100 ml is not recommended, it can be taken if a doctor has prescribed it. Consult a doctor, if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dilantin Oral Suspension 100 ml:
Coadministration of buspirone with Dilantin Oral Suspension 100 ml may drastically lower buspirone levels, making the medicine less effective.

How to manage the interaction:
Taking buspirone with Dilantin Oral Suspension 100 ml can lead to an interaction, it can be taken if recommended by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dilantin Oral Suspension 100 ml:
Coadministration of Dilantin Oral Suspension 100 ml and Everolimus may decrease the blood levels of everolimus, which may make Everolimus less effective.

How to manage the interaction:
Although taking Dilantin Oral Suspension 100 ml and Everolimus together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.

Drug-Food Interactions

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  • Enteral tube feeds: Liquid nutritional formulas can reduce Dilantin Oral Suspension absorption. If you receive tube feeding, follow the specific timing instructions provided by your healthcare team.
  • Alcohol: Alcohol can affect Dilantin Oral Suspension levels and increase dizziness or drowsiness. Avoid alcohol unless your doctor specifically advises otherwise.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

Dilantin Oral Suspension is used to treat epilepsy/seizures and prevent seizures during/after brain surgery or after traumatic brain injury. Besides this, Dilantin Oral Suspension may also be used to treat trigeminal neuralgia (facial nerve pain).
Dilantin Oral Suspension contains Phenytoin, which helps prevent neurons from working at a very fast speed, thereby preventing the brain cells from firing together rapidly in an uncontrolled way. As a result, Dilantin Oral Suspension controls the overactivity of the brain cells that cause seizures. Dilantin Oral Suspension slows down the electrical impulses in the nerves and reduces their ability to transmit pain, thereby treating trigeminal neuralgia.
Dilantin Oral Suspension may affect the breakdown of the blood sugar/glucose and may prevent the release of insulin, thereby leading to high blood sugar. So, contact a doctor before using Dilantin Oral Suspension if you have diabetes.
A seizure generally lasts from a few seconds to a few minutes depending on the type of seizure.
You should take Dilantin Oral Suspension with or without food, as advised by your doctor. Check the label for directions. Shake the bottle well before each use. Take the prescribed dose orally using the measuring cup provided with the package. Avoid using regular household spoons, as they may not accurately measure the dose.
Dilantin Oral Suspension may stay in our system (body) for 5 to 6 days on average. This duration is different for each person. In some cases, it may remain for about 9 to 10 days.
Dilantin Oral Suspension overdose can be fatal and may cause symptoms such as slurred speech, twitching eye movements, muscle stiffness or weakness, tremors, loss of balance, lightheadedness, fainting, vomiting, nausea, and slow or shallow breathing. Also, it may cause very low blood pressure and even coma. Therefore, do not exceed the recommended daily dose.
Patients with liver disease, particularly if they have a history of developing a liver problem due to Dilantin Oral Suspension , should avoid taking Dilantin Oral Suspension . Additionally, anyone taking Delavirdine (a medicine used in the treatment of HIV infection) should not take Dilantin Oral Suspension as it may reduce the effectiveness of Delavirdine against HIV, and the virus may also develop resistance to Delavirdine. It is recommended to consult your doctor before taking Dilantin Oral Suspension if you have any pre-existing heart conditions.
You are recommended to consult your doctor before taking Dilantin Oral Suspension with ibuprofen or other medicines to avoid drug interactions.
The most common side effects of Dilantin Oral Suspension in children are overgrowth of the gums and jerky movements of the eyes (nystagmus). In some children, it causes problems with behaviour or thinking, mood change, loss of energy and slow or clumsy movements. High doses may cause side effects such as vomiting, sleepiness and unsteadiness in the feet and hands. To avoid these, the dose is increased gradually. As soon as the dose is reduced, these side effects disappear.
Dilantin Oral Suspension does not cause weight gain. However, on longer term use of a higher dose of Dilantin Oral Suspension , weight loss can occur. If you experience weight gain after taking Dilantin Oral Suspension , please consult your doctor.
Dilantin Oral Suspension can make you feel sleepy as a side effect. However, if you feel extremely sleepy after taking Dilantin Oral Suspension , especially in the first few weeks of treatment or after a dose increase, please consult your doctor.
The common side effects of Dilantin Oral Suspension include weakness, drowsiness, dizziness, confusion, restlessness, slurred speech, constipation, loss of coordination, and abnormal eye movement. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
No. Being seizure-free does not necessarily mean that the condition has gone away. Stopping Dilantin Oral Suspension suddenly can cause seizures to return or become prolonged and severe. If treatment needs to be stopped, your doctor will usually reduce the dose gradually and monitor you.
Dilantin Oral Suspension oral suspension is generally stored at room temperature and should not be frozen. Keep the bottle tightly closed and protect it from excessive heat and direct light. Follow the storage instructions printed on your specific product.
There is not enough evidence to say that ordinary amounts of caffeine have a clinically important interaction with Dilantin Oral Suspension . However, large amounts of caffeine may affect sleep, and poor sleep can trigger seizures in some people. Keep your caffeine intake moderate and consistent, and discuss any concerns with your healthcare provider.
Yes. Dilantin Oral Suspension can speed up the breakdown of several hormonal contraceptives, making them less reliable. If you use hormonal birth control, speak with your doctor about an effective alternative or additional contraceptive method.
Dilantin Oral Suspension has a narrow therapeutic index, meaning the effective dose and the dose that can cause toxicity are relatively close. Blood tests can help your doctor check whether the medicine level is appropriate, especially after dose changes or when other medicines are started or stopped. Your doctor may also monitor liver function and blood counts when appropriate.
Dilantin Oral Suspension begins affecting abnormal electrical activity after it reaches an effective level in the body, but the time needed to achieve stable seizure control varies between individuals. Your doctor may adjust the dose based on your seizure response and, when necessary, blood Dilantin Oral Suspension levels.
It is best to avoid alcohol while taking Dilantin Oral Suspension . Alcohol can increase dizziness and drowsiness and may unpredictably affect Dilantin Oral Suspension levels or seizure control. If you regularly drink alcohol, discuss this openly with your doctor so your treatment can be managed safely.
Gum swelling or overgrowth is a known effect of Dilantin Oral Suspension , especially with long-term treatment. Brush gently twice a day, floss regularly, and attend routine dental checkups. If your gums become very swollen, painful, or bleed easily, inform your doctor and dentist so the problem can be assessed and managed.

Disclaimer

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Country of origin

INDIA

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051
Other Info - DIL0014
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