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Difsoon P 25mg/75mg Injection belongs to a class of medications known as non-steroidal anti-inflammatory drugs (NSAID) or pain killers used to treat pain, including musculoskeletal pain (pain in the muscles, bones, tendons, ligaments, and nerves), gout attacks, pain caused by kidney stones, pain caused by injuries, fractures or trauma. On the other hand, it may also be used to prevent or treat post-operative pain.
Difsoon P 25mg/75mg Injection contains Diclofenac (analgesic) and Paracetamol (fever reducer/mild analgesic). Diclofenac works by blocking the action of a chemical messenger known as cyclooxygenase (COX), which causes pain and swelling at the injured or damaged tissue site. On the other hand, paracetamol acts as a mild analgesic (mild pain reducer) which enhances the pain relief action of Diclofenac.
Difsoon P 25mg/75mg Injection may cause common side effects such as headache, dizziness, vertigo, nausea, vomiting, diarrhoea, dyspepsia, abdominal pain, flatulence, decreased appetite, and injection site reactions such as local pain and induration. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Tell your doctor if you are allergic to any components in Difsoon P 25mg/75mg Injection. Let your doctor know if you have/had liver or kidney problems; your doctor may need to monitor your liver function. Inform your doctor if you are pregnant, suspect you are pregnant, plan to have a baby or if you are breastfeeding. Difsoon P 25mg/75mg Injection may cause dizziness and loss of balance. If you experience these, you should not drive or operate machinery. Difsoon P 25mg/75mg Injection is not recommended for use in children less than 14 years of age.
Difsoon P 25mg/75mg Injection is used to relieve various types of pain and inflammation. The detailed uses of Difsoon P 25mg/75mg Injection are as follows:
Difsoon P 25mg/75mg Injection belongs to a class of medications known as non-steroidal anti-inflammatory drugs (NSAID) or pain killers used to treat pain, including musculoskeletal pain (pain in the muscles, bones, tendons, ligaments, and nerves), gout attacks, pain caused by kidney stones, pain caused by injuries, fractures or trauma. On the other hand, it may also be used to prevent or treat pain following an operation. Difsoon P 25mg/75mg Injection contains Diclofenac (analgesic) and Paracetamol (fever reducer/mild analgesic). Diclofenac works by blocking the action of a chemical messenger known as cyclooxygenase (COX), which causes pain and swelling at the injured or damaged tissue site. On the other hand, paracetamol acts as a mild analgesic (mild pain reducer) which enhances the pain relief action of Diclofenac.
Caution
Avoid consumption of alcohol while on treatment with Difsoon P 25mg/75mg Injection as it may cause increased dizziness.
Caution
Difsoon P 25mg/75mg Injection should be used during pregnancy only under the supervision of a physician. Difsoon P 25mg/75mg Injection is not recommended during the last trimester as it can lead to fetal damage.
Caution
Difsoon P 25mg/75mg Injection passes into the breast milk. Therefore, if you are breastfeeding, inform your doctor before receiving this medicine.
Caution
Difsoon P 25mg/75mg Injection may cause headaches, blurred vision, dizziness or drowsiness. This may affect your ability to drive. Drive only if you are alert.
Caution
People with severe liver impairment should avoid using Difsoon P 25mg/75mg Injection. In patients with liver impairment, dose adjustments may be required. If you have liver disease or are concerned about this, please discuss it with your doctor.
Caution
People with severe kidney impairment (GFR <15) should avoid using Difsoon P 25mg/75mg Injection. In patients with kidney impairment, dose adjustments may be required. If you have kidney disease or are concerned about this, please discuss it with your doctor.
Unsafe
Difsoon P 25mg/75mg Injection is not recommended for children under 14 years as the safety and effectiveness were not established.
Caution
Difsoon P 25mg/75mg Injection should be used cautiously in heart patients due to diclofenac’s cardiovascular risks. It may increase chances of heart attack, stroke, or worsen heart failure. Always consult your doctor before use to ensure it's safe for your condition.
Caution
Geriatric patients can receive Difsoon P 25mg/75mg Injection, but with caution. Older adults are more vulnerable to side effects like gastrointestinal bleeding, kidney strain, and cardiovascular risks, especially from diclofenac. It's important to use the lowest effective dose under medical supervision.

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Avoid receiving Difsoon P 25mg/75mg Injection if you are allergic to any of its components; if you have gastrointestinal toxicity (peptic ulcers, intestinal bleeding problems), severe kidney (GFR <15) or liver problems. Inform your doctor if you have/had asthma, congestive heart failure, hypertension, fluid retention, blood disorders, and dermatitis (rash). Difsoon P 25mg/75mg Injection may cause dizziness, so drive only if you are alert. Difsoon P 25mg/75mg Injection is not recommended for use during the last trimester of pregnancy and in children below 14 years. Avoid consuming alcohol along with Difsoon P 25mg/75mg Injection as it could lead to increased dizziness.
Drug-Drug Interactions: Difsoon P 25mg/75mg Injection may have interaction with NSAIDs (aspirin, ibuprofen), anticoagulants (warfarin), medicines used to treat epilepsy (phenytoin), drugs used for heart problems (digoxin), anticancer medicines (methotrexate, pemetrexed), immunosuppressant (tacrolimus), quinolone antibiotics (ciprofloxacin), drugs used to reduce cholesterol (colestipol), medicines used to treat liver problems (cholestyramine), drugs used to treat gout (sulfinpyrazone), anti-fungal medication (voriconazole), drugs used in patients having long term blood transfusions (deferasirox), medicines used during termination of pregnancy (mifepristone), HIV medication (zidovudine), certain diabetic medications and diuretic medications.
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Inform your doctor if you have/had a gastric or intestinal ulcer, bleeding or perforation, severe hepatic, renal or cardiac failure, blood disorders, and phenylketonuria (an inherited condition that causes a build-up of phenylalanine (amino acid) in the blood).
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Difsoon P 25mg/75mg Injection belongs to a class of medications known as non-steroidal anti-inflammatory drugs (NSAID) or pain killers used to treat pain, including musculoskeletal pain (pain in the muscles, bones, tendons, ligaments, and nerves), gout attacks, pain caused by kidney stones, pain caused by injuries, fractures or trauma. On the other hand, it may also be used to prevent or treat post-operative pain.
Difsoon P 25mg/75mg Injection contains Diclofenac and Paracetamol. Diclofenac works by blocking the action of a chemical messenger known as cyclooxygenase (COX), which causes pain and swelling at the injured or damaged tissue site. On the other hand, paracetamol enhances the pain relief action of Diclofenac.
Difsoon P 25mg/75mg Injection may increase the risk of a heart attack in people with pre-existing heart conditions if used for prolonged periods. It is also not suitable for treating pain after heart surgery. Use it for the duration as long as your doctor prescribed. It is not recommended for use in patients with heart complications.
Difsoon P 25mg/75mg Injection is not recommended for patients with a known allergy to pain relievers (NSAIDs) or any of the components or excipients in Difsoon P 25mg/75mg Injection. Difsoon P 25mg/75mg Injection should be avoided in patients with a history of stomach ulcers or an ongoing, recurring stomach ulcer/bleeding. It should also be avoided in patients with a history of heart or liver failure and renal illness (Chronic Kidney Disease Grade 5) and during the last trimester of pregnancy.
Difsoon P 25mg/75mg Injection can be used to treat several painful conditions, including pain caused by kidney stones. Consult your doctor if you have any concerns.
Taking anti-inflammatory medications, such as Diclofenac, in excessive dosages or for an extended period of time can interfere with ovulation in women. This may make it more difficult to conceive. Talk to your doctor if you have any concerns.
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