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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Desval ER 250 Tablet is used to treat epilepsy (seizures/fits). It can be used alone or in combination with other medications to treat complex partial seizures that occur alone or alongside other types of seizures. It contains Divalproex sodium, which decreases the brain's excessive and abnormal nerve activity, thereby helping to control seizures. In some cases, it may cause common side effects such as drowsiness, dizziness, and nausea. Before taking this medicine, you should inform your doctor if you are allergic to any of its components, if you are pregnant/breastfeeding, and about all the medications you are taking, as well as any pre-existing medical conditions.

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Manufacturer/Marketer :

Eris Life Sciences Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Desval ER 250 Tablet

Desval ER 250 Tablet belongs to a group of medicines called anticonvulsants or antiepileptics, used to treat epilepsy (seizures/fits). It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures.

The name Desval ER 250 Tablet contains 'Divalproex sodium,' which works by increasing the levels of a natural brain chemical called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, Desval ER 250 Tablet helps control seizures.

Take Desval ER 250 Tablet with or without food. You are advised to take Desval ER 250 Tablet as prescribed by your doctor, depending on your medical condition. In some cases, you may experience certain common side effects, such as drowsiness, dizziness, nausea, back pain, increased appetite, constipation, diarrhoea, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you are allergic to any of its contents, have significant liver disease or dysfunction, or have urea cycle disorders. Do not stop taking Desval ER 250 Tablet without consulting your doctor, as this may worsen seizures. Avoid taking Desval ER 250 Tablet if you are pregnant, as it may cause severe birth defects. Consult your doctor before using Desval ER 250 Tablet if you are breastfeeding. Desval ER 250 Tablet should be given to children only if prescribed by your doctor. Avoid driving or operating machinery, as Desval ER 250 Tablet may cause drowsiness and dizziness. Avoid consuming alcohol along with Desval ER 250 Tablet , as it could lead to increased dizziness.

Uses of Desval ER 250 Tablet

Desval ER 250 Tablet is used in the treatment of epilepsy (seizures). The detailed uses of Desval ER 250 Tablet are as follows:<br/>• It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures.<br/>• It may also be used alone or with other medications to treat both simple and complex absence seizures (which cause a brief loss and return of consciousness for a few seconds).<br/>

Directions for Use

  • Desval ER 250 Tablet can be taken with or without food, or as advised by the doctor.
  • Shake the bottle well before each use.
  • Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided with the pack.
  • Replace the bottle cap tightly after each use.
  • Avoid using regular household spoons, as they may not accurately measure the dose.
  • Your doctor may adjust the dose and frequency of this medication based on your medical condition.

Medicinal Benefits

Desval ER 250 Tablet belongs to a group of medicines called anticonvulsants or antiepileptics, primarily used to treat epilepsy (seizures or fits). It increases the levels of a natural chemical (GABA) in the brain, which helps reduce excessive and abnormal nerve activity in the brain, thereby helping to control seizures. Desval ER 250 Tablet is used alone or in combination with other medications to treat complex partial seizures, whether they occur alone or alongside other types of seizures.

How Desval ER 250 Tablet Works

Desval ER 250 Tablet contains 'Divalproex sodium,' which works by increasing the levels of a natural chemical in the brain called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, Desval ER 250 Tablet helps control seizures.

Storage

• Store in a cool and dry place away from sunlight.• Keep Desval ER 250 Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Desval ER 250 Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Desval ER 250 Tablet

Do not take more than the prescribed dose of Desval ER 250 Tablet , as it may lead to an overdose. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you suspect you have taken an overdose or notice any of these symptoms, please consult a doctor immediately.

Drug Warnings

Do not take Desval ER 250 Tablet if you are allergic to any of its contents, have significant liver disease or dysfunction, or have urea cycle disorders. Inform your doctor before taking Desval ER 250 Tablet if you have pancreatitis, blood problems, or multi-organ hypersensitivity. Consult your doctor immediately if you experience suicidal tendencies while taking Desval ER 250 Tablet . Desval ER 250 Tablet may cause thrombocytopenia (low blood platelets), hyperammonemia (high levels of ammonia in the blood), hypothermia (low body temperature), and liver problems. Please do not stop taking Desval ER 250 Tablet without consulting your doctor to avoid worsening of seizures. Do not take Desval ER 250 Tablet if you are pregnant, as it could cause serious birth defects. If you are of childbearing age, use effective contraception while taking Desval ER 250 Tablet . Consult your doctor before taking Desval ER 250 Tablet if you are breastfeeding. Desval ER 250 Tablet should be given to children only if prescribed by your doctor. Avoid driving or operating machinery, as Desval ER 250 Tablet may cause drowsiness and dizziness. Avoid consuming alcohol along with Desval ER 250 Tablet , as it could lead to increased drowsiness and dizziness.

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical
How does the drug interact with Desval ER 250 Tablet:
Coadministration of Glycerol phenylbutyrate and Desval ER 250 Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Glycerol phenylbutyrate and Desval ER 250 Tablet together is generally avoided as it can lead to an interaction, it can be taken when your doctor advises. If you experience any symptoms like sudden dizziness, headaches, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Desval ER 250 Tablet:
Coadministration of Ketoconazole and Desval ER 250 Tablet may increase the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Desval ER 250 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain, fatigue, nausea, vomiting, stomach pain, dark urine, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexMipomersen
Severe
How does the drug interact with Desval ER 250 Tablet:
Co-administration of Desval ER 250 Tablet and mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Desval ER 250 Tablet and mipomersen can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult the doctor immediately. Avoid alcohol consumption, and Do not stop using any medications without a doctor's advice.
How does the drug interact with Desval ER 250 Tablet:
Co-administration of buprenorphine with Desval ER 250 Tablet may increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Buprenorphine with Desval ER 250 Tablet can result in an interaction, it can be taken when a doctor has advised it. However, if you experience shortness of breath, irregular heart rhythms, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Desval ER 250 Tablet:
Co-administration of Desval ER 250 Tablet and leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Desval ER 250 Tablet and leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
DivalproexEsketamine
Severe
How does the drug interact with Desval ER 250 Tablet:
Coadministration of Esketamine and Desval ER 250 Tablet can increase the side effects of esketamine.

How to manage the interaction:
Although taking Desval ER 250 Tablet and Esketamine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any symptoms like drowsiness and impaired motor coordination, consult the doctor immediately. Do not stop using any medications without talking to your doctor.
How does the drug interact with Desval ER 250 Tablet:
Co-administration of Desval ER 250 Tablet and Doripenem can reduce the blood levels of Desval ER 250 Tablet sodium and increase the risk of developing seizures.

How to manage the interaction:
Co-administration of Desval ER 250 Tablet with Doripenem can possibly result in an interaction, it can be taken when your doctor has advised it. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Desval ER 250 Tablet:
Coadministration of Desval ER 250 Tablet and Lamotrigine can increase the risk and severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Desval ER 250 Tablet and Lamotrigine, you can take these medicines together if prescribed by your doctor. However, contact your doctor if you experience restlessness, rash, or muscle weakness. Do not stop using any medications without a doctor's advice.
How does the drug interact with Desval ER 250 Tablet:
Coadministration of Ertapenem with Desval ER 250 Tablet may reduce the blood levels of Desval ER 250 Tablet and increase the risk of developing seizures.

How to manage the interaction:
Although there is a possible interaction, ertapenem can be taken with Desval ER 250 Tablet if prescribed by the doctor. Consult the doctor if you experience loss of seizure control or changes in behaviour. Do not stop using any medications without talking to your doctor.
DivalproexLomitapide
Severe
How does the drug interact with Desval ER 250 Tablet:
Co-administration of Desval ER 250 Tablet and Lomitapide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Desval ER 250 Tablet and lomitapide can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like fever, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without the doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for energy generation of energy.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps maintain weight and improve overall health.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try to reduce or avoid them.
  • Please pay attention to your overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Desval ER 250 Tablet , as it may cause increased drowsiness and dizziness.

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Pregnancy

Unsafe

Desval ER 250 Tablet belongs to pregnancy category D. Avoid taking Desval ER 250 Tablet if you are pregnant, as it could lead to serious birth defects. Consult your doctor for further advice.

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Breast Feeding

Caution

Desval ER 250 Tablet may pass into breastmilk. Consult your doctor before taking Desval ER 250 Tablet if you are breastfeeding.

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Driving

Unsafe

Desval ER 250 Tablet causes drowsiness and dizziness. Therefore, do not drive or operate machinery until you are mentally alert.

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Liver

Unsafe

Desval ER 250 Tablet should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Desval ER 250 Tablet should be given to children only if prescribed by a doctor.

Have a query?

FAQs

Desval ER 250 Tablet belongs to a group of medicines called anticonvulsants or antiepileptics, used to treat epilepsy (seizures/fits). It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures.

Desval ER 250 Tablet contains 'Divalproex sodium,' which works by increasing the levels of a natural chemical in the brain called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, Desval ER 250 Tablet helps control seizures.

Do not discontinue Desval ER 250 Tablet without consulting your doctor. To treat your condition effectively, continue taking Desval ER 250 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Desval ER 250 Tablet , your doctor will reduce the dose gradually to avoid worsening of seizures.

Desval ER 250 Tablet may cause weight gain due to increased appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective method of contraception during the treatment with Desval ER 250 Tablet . Avoid getting pregnant while taking Desval ER 250 Tablet as it could lead to severe birth defects. Do not stop taking Desval ER 250 Tablet and consult your doctor immediately if you become pregnant.

Desval ER 250 Tablet may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking Desval ER 250 Tablet .

Topiramate (an anticonvulsant) should not be taken along with Desval ER 250 Tablet as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature), and liver problems.

It is crucial to consult with your doctor before discontinuing Desval ER 250 Tablet . Abruptly stopping this medication can lead to severe consequences, mainly if it's prescribed to treat conditions like epilepsy.

Desval ER 250 Tablet can indeed make you sleepy. This is a common side effect of the medication. If you're experiencing excessive drowsiness, please consult your doctor.

Yes, Desval ER 250 Tablet can cause hair loss as a side effect. While this isn't a common side effect, it can occur in some people. If you notice significant hair loss while taking Desval ER 250 Tablet , it's essential to consult with your doctor.

Yes, Desval ER 250 Tablet can potentially damage your liver. While this is a rare side effect, being aware of the risk is essential. Signs of liver damage may include yellowing of the skin or eyes or jaundice, dark urine, abdominal pain, light-coloured stools, nausea and vomiting. If you experience any of these symptoms while taking Desval ER 250 Tablet , seeking medical attention is crucial.

Avoid consumption of alcohol while taking Desval ER 250 Tablet , as it may cause increased drowsiness and dizziness.

If you experience abdominal pain, nausea, and anorexia while taking Desval ER 250 Tablet , it's essential to contact your doctor immediately. These symptoms can be signs of a severe side effect, such as liver damage.

An overdose of Desval ER 250 Tablet can be a severe medical emergency. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you or someone you know has taken an overdose of Desval ER 250 Tablet , please seek immediate medical attention.

The common side effects of Desval ER 250 Tablet include drowsiness, dizziness, nausea, back pain, increased appetite, constipation, diarrhoea, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - DES0010

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