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About Desrem 100 Injection
Desrem 100 Injection belongs to a group of anti-viral medicines called SARS-CoV-2 nucleotide analogue RNA polymerase inhibitor used to treat coronavirus disease requiring hospitalisation. Coronavirus disease, also known as SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona Virus 2), is an infectious disease caused by the corona virus.
Desrem 100 Injection contains ‘Remdesivir, which binds to the viral-RNA dependant RNA polymerase enzyme, an enzyme that helps the coronavirus to replicate itself. This inhibits viral replication by premature termination of RNA transcription. Thereby, Desrem 100 Injection lowers the virus load in the body and helps treat the infection.
Desrem 100 Injection will be administered by a healthcare professional in a hospital or a healthcare setting capable of providing in-patient hospital care. In some cases, you may experience certain side effects such as nausea, increased transaminase levels, and increased prothrombin time. You are advised to talk to your doctor if you experience these side effects persistently.
Consult your doctor if you are pregnant, think you are pregnant or breastfeeding. Transaminase levels should be monitored before and during the treatment with Desrem 100 Injection. Keep your doctor informed about your health condition and the medicines you are taking to prevent any side effects/interactions.
Uses of Desrem 100 Injection
Directions for Use
Medicinal Benefits
Desrem 100 Injection belongs to a group of anti-viral medicines called SARS-CoV-2 nucleotide analogue RNA polymerase inhibitor. Desrem 100 Injection is used to treat corona virus disease requiring hospitalisation. Desrem 100 Injection binds to the viral-RNA-dependant RNA polymerase enzyme, an enzyme that helps the corona virus to replicate itself. This inhibits viral replication by premature termination of RNA transcription. Thereby, Desrem 100 Injection lowers virus load in the body and helps treat the infection.
How Desrem 100 Injection Works
Storage
What if I have taken an overdose of Desrem 100 Injection
Drug Warnings
Do not take Desrem 100 Injection if you are allergic to any of its contents. Inform your doctor if you have heart, liver or kidney problems. Consult your doctor before taking Desrem 100 Injection if you are pregnant, think you are pregnant or breastfeeding. Desrem 100 Injection is indicated for use only in patients above 12 years, weighing at least 40kg. Transaminase levels should be monitored before and during the treatment with Desrem 100 Injection. Treatment with Desrem 100 Injection should be discontinued if the ALT (Alanine aminotransferase) levels are greater than ten times the upper limit of normal. Keep your doctor informed about your health condition and the medicines you are taking to prevent any side effects/interactions.
Drug-Drug Interactions
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Diet & Lifestyle Advise
Habit Forming
Therapeutic Class
Product Substitutes
Alcohol
Caution
It is not known whether Desrem 100 Injection interacts with alcohol. Please consult your doctor.
Pregnancy
Caution
There is insufficient data regarding the safety of Desrem 100 Injection during pregnancy. Please consult a doctor if you are pregnant or think you might be pregnant.
Breast Feeding
Caution
There is insufficient data regarding the passage of Desrem 100 Injection into breastmilk. Please consult a doctor if you are breastfeeding.
Driving
Caution
It is unknown if Desrem 100 Injection affects your ability to drive. Drive or operate machinery only if you are alert.
Liver
Caution
The effectiveness of Desrem 100 Injection in patients with liver impairment have not been evaluated. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
Caution
The effectiveness of Desrem 100 Injection in patients with kidney impairment have not been evaluated. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Caution
Please consult your doctor if you have any concerns regarding the usage of Desrem 100 Injection in children.
Have a query?
Desrem 100 Injection binds to the RNA polymerase enzyme, an enzyme that helps the coronavirus to replicate itself. This inhibits viral replication by premature termination of RNA transcription. Thereby, Desrem 100 Injection lowers the virus load in the body and helps treat the infection.
Desrem 100 Injection should not be taken along with chloroquine phosphate and hydroxychloroquine sulphate as it might cause reduced anti-viral activity of Desrem 100 Injection. Co-administration of these drugs is not recommended.
No, Desrem 100 Injection is not indicated for the prevention of coronavirus disease. Desrem 100 Injection has been approved by DCGI (Drug Control General of India) for emergency use only in patients who are COVID-positive.
Regularly clean your hands thoroughly using soap and water or an alcohol-based sanitiser. Avoid touching your nose, eyes, and mouth without washing your hands. Clean and disinfect surfaces regularly. Always remember to wear a mask, maintain social distance and avoid gatherings.
Covid-19 spreads through respiratory droplets when in close or direct contact with an infected person. The virus can spread through an infected person’s sneeze or cough. The virus can also be transmitted by touching any contaminated surfaces and then touching the nose, mouth or eyes without washing the hands.
Desrem 100 Injection belongs to a group of anti-viral medicines called SARS-CoV-2 nucleotide analogue RNA polymerase inhibitor used to treat coronavirus disease requiring hospitalisation.
Inform your doctor, if you are allergic to any of its contents. If you have heart, liver or kidney problems or if you are using any other medications. And also let your doctor know if you are breastfeeding, pregnancy or planning pregnancy before starting Desrem 100 Injection to avoid possible interactions.
Not every patient with COVID-19 requires Desrem 100 Injection. It is specifically recommended for adults and children hospitalized with severe COVID-19 who require oxygen therapy or are on a ventilator. However, always consult your doctor for personalized medical advice.
COVID-19 is a respiratory illness caused by the SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona Virus 2) virus. The common symptoms of corona virus disease are dry cough, breathlessness, shortness of breath, tiredness, fever, loss of sense of taste and smell, diarrhoea, body pains, headache and sore throat.
An Emergency Use Authorization (EUA) is a mechanism used by the U.S. food and drug administration (FDA) to expedite the availability and use of medical products, such as drugs and vaccines, during public health emergencies. EUA's are typically issued during situations like the COVID-19 pandemic to quickly provide access to critical medical countermeasures.
Desrem 100 Injection is administered intravenously (IV), by a healthcare professional in a hospital or healthcare setting. Do not self-administer.
Desrem 100 Injection is used to treat hospitalized patients who are suffering with severe COVID-19.
The common side effects of Desrem 100 Injection are nausea, increased transaminase levels and increased prothrombin time. If any of these side effects persist or worsen, please consult your doctor.
Yes, Desrem 100 Injection is generally considered safe when used under the supervision of a healthcare professional. However, like all medications, it can have side effects. So it's important to monitor for any adverse reactions and inform your doctor if you any side effects persist or worsen.
A pregnant women infected with covid-19 should take the advice of a doctor as there is limited data on the safety of Desrem 100 Injection during pregnancy.
If you are suffering from diabetes and high blood pressure, you should take your doctor’s advice before taking Desrem 100 Injection.
Desrem 100 Injection should only be administered to those with laboratory-confirmed COVID-19 infection to ensure its appropriate use and effectiveness. However, consult your doctor, if you are highly suspected with COVID -19 symptoms.
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