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compositionComposition:DEXRABEPRAZOLE-10MG
prescription
Prescription Medicine
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Desprazole Tablet 10's is used to treat gastroesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome. It contains Dexrabeprazole which reduces the amount of acid produced by the stomach and prevents acid reflux. In some cases, this medicine may cause side effects such as diarrhoea, nausea, vomiting, headache, dizziness, stomach pain or constipation. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DEXRABEPRAZOLE-10MG

Manufacturer/Marketer :

Medihealth Lifesciences India Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Desprazole Tablet 10's

Desprazole Tablet 10's is an oral prescription medication used to treat conditions caused by excess stomach acid, such as gastroesophageal reflux disease (GERD) and stomach ulcers. It works by reducing the amount of acid your stomach produces, helping to relieve symptoms like heartburn, acid regurgitation, and difficulty swallowing. This medication helps heal acid damage to the stomach and oesophagus, preventing more serious complications over time.

For the best results, you should take Desprazole Tablet 10's consistently every day, exactly as prescribed by your doctor. It is typically taken once daily, usually in the morning on an empty stomach, at least 30 minutes before your first meal. Making simple lifestyle adjustments, such as eating smaller meals and avoiding eating right before bed, can also significantly improve your recovery.

While taking Desprazole Tablet 10's, you might experience mild side effects like headaches, mild diarrhoea, or stomach pain. These usually go away as your body adjusts to the medicine, but you should contact your healthcare provider immediately if you experience severe diarrhoea, muscle spasms, or signs of an allergic reaction.

Talk to your doctor before starting Desprazole Tablet 10's if you have severe liver damage, low magnesium levels, or osteoporosis. Do not take this if you are allergic to this medication or similar acid-reducing drugs.

This medication can interact with certain blood thinners or antifungal drugs, potentially changing how they work in your body. It is also wise to limit alcohol and avoid smoking, as both can worsen stomach irritation and reduce the effectiveness of your treatment. If you are pregnant, breastfeeding, or an elderly individual, consult your doctor or pharmacist before using this medicine to ensure it is safe for you.

Uses of Desprazole Tablet 10's

Desprazole Tablet 10's is used in the treatment of conditions caused by excess stomach acid. The detailed uses of Desprazole Tablet 10's are as follows:

  • Gastroesophageal Reflux Disease (GERD): Desprazole Tablet 10's reduces stomach acid flow back into the food pipe, relieving heartburn, chest discomfort, and sour taste.
  • Stomach and Duodenal Ulcers: Desprazole Tablet 10's lowers acid levels to allow painful sores in the stomach or upper intestine lining to heal.
  • Erosive Esophagitis: Desprazole Tablet 10's protects the lining of the food pipe from acid damage, allowing it to heal over time.
  • Zollinger-Ellison Syndrome: Desprazole Tablet 10's manages the extremely high levels of stomach acid produced by rare tumours in the pancreas or gut.ed to treat conditions like Zollinger-Ellison syndrome, where the stomach produces too much acid.

Key Benefits

Desprazole Tablet 10's helps manage digestive problems caused by excess stomach acid and reduces the risk of recurring acid-related problems.

Benefits may include:

  • Helps relieve heartburn and acid reflux.
  • Reduces stomach acid to improve digestive comfort.
  • Supports the healing of stomach and oesophageal ulcers.
  • Promotes healing of inflammation caused by acid reflux.
  • Helps prevent the recurrence of acid-related ulcers.
  • Improves overall comfort and quality of life with regular treatment.

Directions for Use

  • Swallow the medicine whole with a full glass of water. Do not crush, chew, or break it, as this can destroy its protective coating.
  • Take this medicine in the morning, preferably 30 minutes before breakfast.
  • Always follow your doctor's exact instructions regarding how long you need to continue taking this medication.

How Desprazole Tablet 10's Works

Desprazole Tablet 10's contains Dexrabeprazole, which belongs to a class of medications known as proton pump inhibitors. Inside your stomach lining, there are tiny cellular structures called proton pumps that are responsible for secreting stomach acid. This medication works by directly binding to and shutting down these proton pumps. By blocking the final step of acid production, it significantly reduces the volume of acid in your stomach, creating a less acidic environment that allows irritated tissues to heal.
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Alcohol

Unsafe

Avoid alcohol consumption as it may lead to increased production of stomach acid, thereby irritates the stomach lining and worsen the symptoms.

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Pregnancy

Caution

Desprazole Tablet 10's is a category B pregnancy drug and is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Desprazole Tablet 10's is usually contraindicated in breastfeeding mothers. Therefore, please consult a doctor before taking Desprazole Tablet 10's if you are breastfeeding.

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Driving

Caution

Desprazole Tablet 10's may cause drowsiness in some people. Therefore, avoid driving or operating machinery if you feel drowsy after taking Desprazole Tablet 10's.

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Liver

Caution

Take Desprazole Tablet 10's with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Desprazole Tablet 10's with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Desprazole Tablet 10's is not recommended for children as the safety and effectiveness were not established.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Desprazole Tablet 10's. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Desprazole Tablet 10's in elderly patients. Please consult your doctor.

What if I have taken an overdose of Desprazole Tablet 10's

If you accidentally take too much Desprazole Tablet 10's, seek immediate medical attention or contact a poison control centre right away, even if you do not feel any symptoms.

Diet & Lifestyle Advise

  • Eat smaller meals: Have smaller, more frequent meals instead of three large meals to reduce pressure on your stomach and help prevent discomfort.
  • Avoid trigger foods: Limit foods and drinks that may worsen symptoms, such as spicy foods, citrus fruits, tomatoes, caffeine, chocolate, and carbonated beverages.
  • Stay upright after meals: Remain upright for 2–3 hours after eating and avoid lying down or reclining immediately to reduce the risk of acid reflux.
  • Elevate your sleeping position: Raise the head of your bed by 6–8 inches using bed risers or a wedge pillow to help prevent acid reflux during sleep.
  • Wear comfortable clothing: Choose loose-fitting clothes around your waist to avoid extra pressure on your abdomen and reduce reflux symptoms.
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How Soon It Starts Working

  • The time required for Desprazole Tablet 10's to start to work: Desprazole Tablet 10's ideally shows its action within 1 to 3 hours after administration.
  • The time for which the effects of Desprazole Tablet 10's last: The effect of Desprazole Tablet 10's lasts for 24 hours.

What if you forget to take Desprazole Tablet 10's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep Desprazole Tablet 10's out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Check the expiry date: Always check the expiry date on the package before taking this medicine. Do not use it if it has expired.
  • Inspect the packaging: Make sure the blister pack or bottle is not damaged, and the tablets look normal. Do not take the medicine if the tablets are cracked or have changed colour.
  • Inform your healthcare provider: Tell your doctor or any healthcare professional that you are taking Desprazole Tablet 10's, especially before an endoscopy or certain blood tests.
  • Attend regular monitoring if needed: If you use this medicine for a long time, your doctor may check your magnesium levels or kidney function through blood tests.
  • Do not share your medicine: Never give this medicine to others, even if they have similar symptoms like acidity, heartburn, or acid reflux.

Drug-Drug Interactions

verifiedApollotooltip
  • Antifungal medicines (e.g., ketoconazole, itraconazole): Taking these medicines alongside Desprazole Tablet 10's may reduce their absorption and decrease their effectiveness.
  • Blood thinners (e.g., warfarin): Taking these medicines with Desprazole Tablet 10's may increase blood thinner levels and raise the risk of bleeding, which may require closer monitoring.
  • Antiviral medicines (e.g., atazanavir): Taking these medicines alongside Desprazole Tablet 10's may reduce the effectiveness of the antiviral treatment.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Food: Taking this medication with food may delay its absorption, which is why it is best taken on an empty stomach.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTACIDS]

FAQs

Desprazole Tablet 10's is used to treat gastroesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome.
Desprazole Tablet 10's contains Dexrabeprazole that works by blocking the action of proton pumps that are involved in producing stomach acid. Thereby, Desprazole Tablet 10's reduces the amount of acid produced by stomach and prevents excess acid flowing back into foodpipe. Thus, provides relief from heartburn symptoms related to acid reflux.
Desprazole Tablet 10's may cause diarrhoea as a common side effect. However, if the condition persists or worsens with fever, watery or bloody stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking Desprazole Tablet 10's to prevent dehydration.
Desprazole Tablet 10's may cause low levels of magnesium in the blood if taken for more than 3 months. If you experience involuntary muscle contractions, tiredness, fits, increased heart rate or dizziness while taking Desprazole Tablet 10's, please consult a doctor immediately as these might be signs of low magnesium levels. However, regular blood tests are recommended to monitor magnesium levels in the blood while taking Desprazole Tablet 10's.
You are not recommended to take Desprazole Tablet 10's with antifungals such as ketoconazole or itraconazole as it may reduce the effectiveness of antifungal against fungal infections. However, please consult your doctor before taking Desprazole Tablet 10's with other medicines.
Desprazole Tablet 10's should be used with caution in osteoporosis (weak and brittle bones) patients as it may worsen the condition especially if Desprazole Tablet 10's is taken for more than 1 year as it increases the risk of fracture of spine, hip or wrist. Therefore, inform your doctor if have osteoporosis or if you are taking any steroids which may increase the risk of osteoporosis.
Desprazole Tablet 10's may reduce the absorption of vitamin B12 and lead to its deficiency if used for more than 3 years. Therefore, inform your doctor if you have any risk factors for reduced vitamin B12 before taking Desprazole Tablet 10's.
Desprazole Tablet 10's is generally safe when used for the duration prescribed by your doctor. However, using it for more than a year or longer may increase the risk of side effects, such as bone fractures, low magnesium levels, vitamin B12 deficiency, and fundic gland polyps (growths in your stomach lining).
Long-term use of Desprazole Tablet 10's may lead to nutrient deficiencies, particularly in magnesium, calcium, and vitamin B12, due to reduced absorption. This may also increase the risk of bone fractures because of lower calcium levels. Therefore, it is important to follow your doctor's instructions when using Desprazole Tablet 10's, especially for extended periods.
It is generally not recommended to drink alcohol while taking Desprazole Tablet 10's, as alcohol can irritate your stomach lining and may reduce the effectiveness of the medication in treating acid-related conditions.
Yes, you can take Desprazole Tablet 10's (a proton pump inhibitor) with antacids if your doctor advises it. Desprazole Tablet 10's works best when your stomach is less acidic, and antacids can change the acidity in your stomach. To avoid any possible interference, it is advisable to maintain a gap of 2 hours between Desprazole Tablet 10's and antacid medicines.
You should not stop taking Desprazole Tablet 10's suddenly without consulting your doctor, even if your symptoms have completely disappeared. Stopping too early can cause your stomach to produce excess acid, leading to a return of your symptoms. Talk to your doctor to plan a safe way to stop using the medication.
Desprazole Tablet 10's usually starts working within an hour of taking it. You may begin to feel better within 2 to 3 days, but it can take up to 4 weeks for your symptoms to fully improve.
The common side effects of Desprazole Tablet 10's include diarrhoea, nausea, vomiting, headache, dizziness, stomach pain, and constipation. Most of these side effects of Desprazole Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
It is highly recommended to take Desprazole Tablet 10's on an empty stomach, typically 30 minutes before your morning meal. Taking it with food can delay its absorption and make it less effective. Talk to your doctor or pharmacist if you have questions about timing.
If you miss a dose, take it as soon as you remember. However, if your next dose is only a few hours away, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one. Talk to your doctor or pharmacist if you frequently miss doses.
Taking medications like Desprazole Tablet 10's in high doses or for a year or longer may increase the risk of bone fractures, especially in older adults. If you have osteoporosis or are at risk for bone loss, discuss this with your healthcare provider. Talk to your doctor about ways to protect your bone health.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.2842 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Rabeprazole Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. National Health Service (NHS). Rabeprazole - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Bethesda (MD). Dexrabeprazole. NIH National Library of Medicine, National Center for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 19th December 2022]Check here
  5. Antunes C, Aleem A, Curtis SA. Gastroesophageal Reflux Disease. NIH National Library of Medicine, National Center for Biotechnology Information. StatPearls. July 2022. [Accessed on 19th December 2022]Check here
  6. Kanakia R, Jain S. Ten mg dexrabeprazole daily is as effective as 20 mg rabeprazole daily. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. July 2008. [Accessed on 19th December 2022]Check here
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed on 28 Mar. 2019]Check here

Country of origin

India

Manufacturer/Marketer address

B-4/155, Yamuna Vihar, New Delhi 110 053 (India)
Other Info - DES0134

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