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compositionComposition:DAPSONE-100MG
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Prescription Medicine
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Depsone 100mg Tablet is used to treat leprosy (Hansen's disease), dermatitis herpetiformis (a skin problem), and Actinomycotic mycetoma (a fungal disease). It is also used to prevent malaria and pneumonia. It contains Dapsone, which works by inhibiting the growth or killing bacteria or fungi that cause infection. Common side effects of Depsone 100mg Tablet are haemolysis (destruction of red blood cells), tiredness, shortness of breath, or a bluish tinge to the skin.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DAPSONE-100MG

Manufacturer/Marketer :

Hul Nutrition

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Depsone 100mg Tablet

Depsone 100mg Tablet is a prescription medicine used to treat dermatitis herpetiformis, which is a severe, intensely itchy skin rash linked to gluten sensitivity. It is also taken in combination with other medicines to treat leprosy, a chronic bacterial infection that affects the skin, nerves, and mucous membranes. Additionally, doctors may prescribe it to prevent certain types of serious lung infections in people with compromised immune systems.

To get the best results from Depsone 100mg Tablet, you must take it consistently and exactly as your doctor prescribes. It can be taken with or without food, though taking your dose with a meal can help prevent mild stomach upset. If you are taking this medicine for a gluten-sensitive skin condition, making strict dietary changes is also necessary to help control your symptoms over time.

While taking Depsone 100mg Tablet, you may experience mild side effects like nausea, headache, or trouble sleeping. However, you must seek medical help immediately if you notice serious signs of blood or liver problems, such as unusual pale skin, extreme tiredness, dark urine, or a bluish tint on your lips and fingertips.

Talk to your doctor before starting this medicine if you have certain health conditions, especially anaemia, liver disease, kidney problems, or a genetic condition called G6PD deficiency. Do not take this if you have had a severe allergic reaction to sulfone medicines in the past.

Some medicines, such as certain antibiotics or tuberculosis treatments, can interact with Depsone 100mg Tablet and change how it works or increase your risk of side effects. It is also important to consult your healthcare provider if you are pregnant, planning to become pregnant, breastfeeding, or if you are an older adult, as special monitoring may be required.

Uses of Depsone 100mg Tablet

Depsone 100mg Tablet is used to treat dermatitis herpetiformis. The detailed uses of Depsone 100mg Tablet are as follows:

  • Dermatitis herpetiformis: Depsone 100mg Tablet helps relieve the severe itching, burning, and blistering skin rashes associated with this chronic autoimmune condition.
  • Leprosy: Depsone 100mg Tablet works alongside other medications to target and clear the bacteria responsible for leprosy, helping to heal skin lesions and protect your nerves.
  • Pneumocystis pneumonia prevention: Depsone 100mg Tablet helps protect individuals with weakened immune systems from developing this serious, opportunistic lung infection.

Key Benefits

Depsone 100mg Tablet helps treat certain bacterial infections and relieve associated skin inflammation and irritation. By controlling the infection and reducing discomfort, it supports healing and improves overall comfort.

  • Relieves Itchy and Inflamed Skin Rashes: By calming skin inflammation, Depsone 100mg Tablet helps reduce itching, redness, irritation, and discomfort, which can improve sleep and daily comfort.
  • Treats Bacterial Infections Effectively: By stopping the growth of susceptible bacteria, Depsone 100mg Tablet helps clear the infection, supports recovery, and reduces the risk of the infection spreading.
  • Supports Protection Against Serious Infections: In people at increased risk of severe infections, Depsone 100mg Tablet helps reduce the likelihood of certain serious bacterial complications when used as prescribed by a healthcare professional.
Side effects of Depsone 100mg Tablet
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Stay hydrated to prevent muscle cramps and spasms.
  • Apply heat therapy to relax muscles and improve blood flow.
  • Try massage therapy to enhance blood flow and promote healing.
  • Incorporate light stretching and exercises to strengthen muscles and improve circulation.
  • Maintain a healthy diet rich in anti-inflammatory foods like ginger, garlic, and turmeric.
  • Engage in regular exercise to strengthen leg muscles and prevent pain.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

Directions for Use

  • Depsone 100mg Tablet should be used exactly as prescribed by your doctor, typically once daily, with or without food.
  • Swallow the tablet whole with water, and try to take it at the same time each day to maintain consistent levels in the body.
  • Do not stop or adjust the dose on your own, even if symptoms improve, as this can lead to resistance or recurrence of infection.

How Depsone 100mg Tablet Works

Depsone 100mg Tablet contains dapsone, which belongs to a group of medicines known as sulfones. It works in two distinct ways to help your body heal. First, it acts as an antibacterial agent by stopping bacteria and other disease-causing organisms from producing folic acid, which they need to grow and multiply. Second, it has natural anti-inflammatory properties that suppress the activity of certain white blood cells (neutrophils). By calming these overactive cells, the medicine quickly reduces the painful redness, swelling, and blistering on your skin.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption with Depsone 100mg Tablet as it may worsen the side effects of Depsone 100mg Tablet.

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Pregnancy

Consult your doctor

Depsone 100mg Tablet is not recommended for use during pregnancy unless your doctor prescribes it. Therefore, please inform your doctor if you are pregnant or planning pregnancy before taking Depsone 100mg Tablet.

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Breast Feeding

Unsafe

Dapsone may pass into breast milk. Therefore, it is recommended to avoid breastfeeding while taking Depsone 100mg Tablet or discontinue using Depsone 100mg Tablet while breastfeeding as this medicine may cause blood disorders in the babies. Hence, please inform your doctor if you are breastfeeding before taking Depsone 100mg Tablet.

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Driving

Safe if prescribed

Depsone 100mg Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Depsone 100mg Tablet with caution, if you have a history of liver diseases/conditions. Your doctor may adjust the dose of this medicine if necessary based on your condition.

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Kidney

Caution

Take Depsone 100mg Tablet with caution, if you have a history of kidney diseases/conditions. Your doctor may adjust the dose of this medicine if necessary based on your condition.

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Children

Caution

Children under the age of six should not use Depsone 100mg Tablet because its safety and efficacy have not been proven. Typically, for kids older than 6 years, the dose is determined by the child's weight.

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Heart

Caution

Take Depsone 100mg Tablet with caution if you have a history of heart diseases/conditions. Your doctor may adjust the dose of this medicine if necessary based on your condition.

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Geriatrics

Consult your doctor

Limited information available about the use of Depsone 100mg Tablet in geriatric patients. Please consult your physician.

What if I have taken an overdose of Depsone 100mg Tablet

If you accidentally take too much of this medicine, seek immediate medical attention or call your local emergency services. Symptoms of an overdose may include severe breathing problems, blue lips or skin, nausea, vomiting, or seizures.

Diet & Lifestyle Advise

  • Follow a strict gluten-free diet: If you are taking Depsone 100mg Tablet for dermatitis herpetiformis, maintaining a strict gluten-free diet is essential. While the medicine controls the painful skin rash, a gluten-free diet treats the underlying cause and may eventually allow your doctor to reduce your medicine dose.
  • Eat folate-rich foods: Because this medicine can affect your red blood cells, talk to your doctor about incorporating foods rich in folate (like leafy greens and citrus fruits) into your diet, or taking a supplement if recommended.
  • Protect your skin from the sun: This medication can make your skin more sensitive to sunlight. Wear protective clothing, hats, and apply a broad-spectrum sunscreen when outdoors.
  • Limit or avoid alcohol: Avoid drinking alcohol while taking this medicine, as both alcohol and the medication can place extra strain on your liver.
health query

Have a query?

How Soon It Starts Working

The time required for Depsone 100mg Tablet to start to work: The exact onset time of Depsone 100mg Tablet has not been clinically established. The time for which the effects of Depsone 100mg Tablet last: The duration of Depsone 100mg Tablet’s effect is clinically not established.

What if you forget to take Depsone 100mg Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store Depsone 100mg Tablet oral tablets at room temperature, ideally between 68°F to 77°F (20°C to 25°C).

Drug Warnings

  • Get regular blood tests: Your doctor will need to perform frequent blood tests, especially during the first few weeks of treatment, to monitor your red blood cells, liver function, and kidney health.
  • Know your G6PD status: Ensure your doctor knows if you have G6PD deficiency before starting this medicine, as this genetic condition increases the risk of severe red blood cell damage.
  • Check your tablets: Always inspect your tablets before taking them; do not take any tablets that are discoloured, crumbling, or damaged.
  • Watch for fever or sore throat: Inform your doctor immediately if you develop a fever, sore throat, or unusual bruising, as these can be early signs of a serious blood-related side effect.
  • Avoid strenuous activities if fatigued: If you experience mild fatigue or shortness of breath due to temporary changes in your red blood cells, avoid extreme physical exertion and rest as needed.

Drug-Drug Interactions

verifiedApollotooltip

  • Rifampin: May lower the levels of Depsone 100mg Tablet in your blood, making your treatment less effective.
    Trimethoprim: Can increase the levels of both medicines in your body, raising the risk of side effects.
  • Medicines that affect blood cells: Taking this with other drugs known to cause red blood cell breakdown or oxygen delivery issues can increase the risk of severe blood complications.
DapsoneSaquinavir
Critical
DapsoneAminolevulinic acid
Severe

Drug-Drug Interactions

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DapsoneSaquinavir
Critical
How does the drug interact with Depsone 100mg Tablet:
Using saquinavir together with Depsone 100mg Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Depsone 100mg Tablet with Saquinavir is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medication without doctor's advice.
DapsoneAminolevulinic acid
Severe
How does the drug interact with Depsone 100mg Tablet:
Taking Aminolaevulinic acid with Depsone 100mg Tablet may increase the risk of sensitivity to light which may leads to severe sunburn.

How to manage the interaction:
Although taking Depsone 100mg Tablet and Aminolaevulinic acid together can cause an interaction, it can be taken if a doctor has suggested it. If you notice that your skin is very sensitive to sunlight or if you have a really bad sunburn, it's important to contact a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Depsone 100mg Tablet:
Taking Depsone 100mg Tablet with Levobupivacaine can increase the risk of methemoglobinemia (A condition in which the iron in the hemoglobin molecule is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although there is a possible interaction between Depsone 100mg Tablet and Levobupivacaine, you can take these medicines together if prescribed by a doctor. However, contact a doctor immediately if you experience headache, dizziness, shortness of breath, or a rapid heartbeat. Do not stop using any medications without consulting a doctor.
DapsoneMepivacaine
Severe
How does the drug interact with Depsone 100mg Tablet:
Taking Depsone 100mg Tablet with Mepivacaine can increase the risk of methemoglobinemia. (blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Although there is a possible interaction between Depsone 100mg Tablet and Mepivacaine, you can take these medicines together if prescribed by a doctor. However, contact a doctor immediately if you experience headache, dizziness, shortness of breath, or a rapid heartbeat. Do not stop using any medications without consulting a doctor.
DapsonePrilocaine
Severe
How does the drug interact with Depsone 100mg Tablet:
Taking Depsone 100mg Tablet with Prilocaine can increase the risk of methemoglobinemia. (blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Although there is a possible interaction between Depsone 100mg Tablet and Prilocaine, you can take these medicines together if prescribed by a doctor. However, if you experience headache, dizziness, shortness of breath, or a rapid heartbeat contact a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Depsone 100mg Tablet:
Taking Lansoprazole with Depsone 100mg Tablet may decrease the level or effect of Depsone 100mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Depsone 100mg Tablet and Lansoprazole, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Depsone 100mg Tablet:
Using Cladribine together with Depsone 100mg Tablet may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Depsone 100mg Tablet and Cladribine, you can take these medicines together if prescribed by a doctor. However, if you experience fever, muscle pains, breathing difficulty, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Depsone 100mg Tablet:
Using Deferiprone together with Depsone 100mg Tablet may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Depsone 100mg Tablet and Deferiprone, you can take these medicines together if prescribed by a doctor. However, if you experience fever, muscle aches, shortness of breath, and pain or burning during urination, contact a doctor. Do not stop using any medications without consulting a doctor.
DapsoneProcaine
Severe
How does the drug interact with Depsone 100mg Tablet:
Taking Depsone 100mg Tablet with Procaine can increase the risk of methemoglobinemia. (blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Although there is a possible interaction between Depsone 100mg Tablet and Procaine, you can take these medicines together if prescribed by a doctor. However, contact a doctor immediately if you experience headache, dizziness, shortness of breath, a rapid heartbeat. Do not stop using any medications without consulting a doctor.
How does the drug interact with Depsone 100mg Tablet:
Taking Depsone 100mg Tablet with Chloroprocaine can increase the risk of methemoglobinemia (A condition in which the iron in the hemoglobin molecule is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although there is a possible interaction between Depsone 100mg Tablet and Chloroprocaine, you can take these medicines together if prescribed by a doctor. However, if you experience gray discoloration of the skin, headache, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Depsone 100mg Tablet when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- INFECTIVES]

FAQs

Depsone 100mg Tablet is used to treat Leprosy and Skin problems.
Depsone 100mg Tablet contains Dapsone, an anti-infective that works by inhibiting the growth or killing bacteria or fungi that cause infection.Â
Depsone 100mg Tablet may cause methemoglobinemia (a serious condition that occurs when the oxygen amount in the blood decreases severely) as a side effect. It is not necessary for everyone using Depsone 100mg Tablet to experience this side effect. However, if you notice a grey or blue appearance on your fingernails, lips or inside of your mouth, stop using Depsone 100mg Tablet and consult a doctor immediately.
Depsone 100mg Tablet may reduce the sperm count or reduce the movement of the sperm, making it difficult to make your partner pregnant. However, if you have any concerns regarding this, please discuss them with your doctor.
Depsone 100mg Tablet is not effective against infections caused by viruses such as cold or flu. It is only used to kill bacteria or fungi. Therefore, you are recommended to consult a doctor if you have a cold or flu so that appropriate medication is prescribed.
No, you are not recommended to stop taking Depsone 100mg Tablet without consulting your doctor as it may worsen the condition. Therefore, take Depsone 100mg Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Depsone 100mg Tablet, please consult your doctor.
It is highly recommended to limit or avoid alcohol while taking this medicine. Both alcohol and this medication are processed by your liver, and combining them can increase your risk of liver damage and dizziness. Talk to your doctor for personalised advice.
Your doctor will monitor your blood to check your red blood cell levels, liver enzymes, and kidney function. This medicine can affect your blood cells, and regular testing ensures that you are taking the medicine safely. Talk to your doctor to understand your test schedule.
You must tell your doctor if you have an allergy to sulfa medicines. While Depsone 100mg Tablet is a sulfone and is chemically different from sulfonamide sulfa drugs, some people who are sensitive to sulfa may still experience a reaction. Talk to your doctor to see if this medicine is safe for you.
No, this medicine does not cure the underlying condition, but it is highly effective at controlling and preventing painful skin rashes. To manage the condition long-term and eventually reduce your need for medicine, you must follow a strict gluten-free diet. Talk to your doctor about dietary management.
Some vitamins or supplements may interfere with how this medicine works, particularly if you are taking it to prevent infections. Do not start any new supplements without consulting your healthcare provider first. Talk to your doctor about what is safe to take.
This medicine should only be used during pregnancy if it is clearly needed and prescribed by a doctor, as it can carry risks for the developing baby. It can also pass into breast milk and affect your baby. Talk to your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

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Country of origin

INDIA

Manufacturer/Marketer address

24-25 Floor, One Horizon Center Golf Course Road, DLF Phase 5 Gurgaon 122002, India
Other Info - DEP0074
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