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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

DEPOCILONE-40MG/1ML INJECTION is used to treat the pain of osteoarthritis (OA) in the knee. It helps to reduce the joint pain, stiffness, and swelling associated with inflammatory disorders. It contains triamcinolone acetonide, which belongs to the class of corticosteroids. It works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies. This effect helps reduce swelling, pain, and discomfort.

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Whats That

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Synonym :

TRIAMCINOLONE

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About DEPOCILONE-40MG/1ML INJECTION

DEPOCILONE-40MG/1ML INJECTION belongs to a group of medications called corticosteroids. It is primarily used to treat the pain of osteoarthritis (OA) in the knee and helps to reduce the joint pain, stiffness, and swelling associated with inflammatory disorders. Osteoarthritis is a common type of arthritis in which the cartilage that cushions the bone's ends erodes due to wear and tear over time. Common symptoms are joint pain and stiffness. The risk of osteoarthritis increases with increasing age.

DEPOCILONE-40MG/1ML INJECTION contains ‘triamcinolone acetonide’, which belongs to the class of corticosteroids. It works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies. This effect helps reduce swelling, pain, and discomfort.

A healthcare professional will administer DEPOCILONE-40MG/1ML INJECTION. Do not self-administer. Sometimes DEPOCILONE-40MG/1ML INJECTION may cause certain side effects such as sore throat, runny nose, sinusitis, dizziness, nervousness, cough, contusions (bleeding under the skin) and injection site reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

DEPOCILONE-40MG/1ML INJECTION should be avoided if you are allergic to it. If you are pregnant or breastfeeding, inform your doctor before receiving this injection. It is not recommended for use in children below 12 years of age. DEPOCILONE-40MG/1ML INJECTION is intended for intra-articular use only. If you have osteoporosis (weak bones) or any other bone or joint relations problems, inform your doctor before receiving DEPOCILONE-40MG/1ML INJECTION. DEPOCILONE-40MG/1ML INJECTION may cause dizziness; hence it is advised to avoid driving vehicles or operating machines after receiving this injection.

Uses of DEPOCILONE-40MG/1ML INJECTION

DEPOCILONE-40MG/1ML INJECTION is used in the management of osteoarthritis pain. The detailed uses of DEPOCILONE-40MG/1ML INJECTION are as follows:<br/>• Treat inflammatory and autoimmune conditions: DEPOCILONE-40MG/1ML INJECTION is used to manage disorders like rheumatoid arthritis, lupus, ulcerative colitis, and allergic reactions by suppressing the immune system and reducing inflammation in joints, muscles, and internal organs.<br/>• Relieve joint and soft tissue inflammation: DEPOCILONE-40MG/1ML INJECTION is injected directly into affected joints or tissues to reduce pain, swelling, and stiffness in conditions such as osteoarthritis, bursitis, and tendinitis, improving mobility and comfort.<br/>• Manage skin disorders: DEPOCILONE-40MG/1ML INJECTION is injected into skin lesions to treat conditions like keloids, psoriasis, alopecia areata, and discoid lupus erythematosus by calming localized inflammation and promoting healing.<br/>

Directions for Use

• DEPOCILONE-40MG/1ML INJECTION must be given by a healthcare professional. It is usually administered through an intramuscular (IM) injection or directly into the joint (intra-articular). The healthcare provider will decide the appropriate dose and injection site for you.• Do not self-administer.• Be sure to inform your doctor of any other medications you are taking or any allergies you may have, especially to steroids.

Medicinal Benefits

DEPOCILONE-40MG/1ML INJECTION contains 'Triamcinolone acetonide,' a corticosteroid. It works by blocking the production of certain chemical messengers in the body that cause inflammation and allergies. This effect helps reduce osteoarthritis symptoms such as pain, inflammation, swelling, and stiffness.

How DEPOCILONE-40MG/1ML INJECTION Works

DEPOCILONE-40MG/1ML INJECTION contains ‘triamcinolone acetonide’, which belongs to the class of corticosteroids. It works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies. This effect helps reduce swelling, pain, and discomfort.

Storage

• Store in a cool and dry place away from sunlight.• Keep DEPOCILONE-40MG/1ML INJECTION out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of DEPOCILONE-40MG/1ML INJECTION

As DEPOCILONE-40MG/1ML INJECTION is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Please inform your doctor if you are allergic to it and if you are using any prescription or non-prescription medicines, including vitamin and herbal supplements, before receiving DEPOCILONE-40MG/1ML INJECTION. This medicine weakens your immune system, making you more prone to infections. So, keep a distance from people who are sick or have infections. Pregnant and breastfeeding mothers should avoid receiving this medicine as it may cause serious side effects to the developing baby. DEPOCILONE-40MG/1ML INJECTION is not recommended for use in children 12 years of age as the safety and efficacy are not established. If you have osteoporosis (weak bones) or any other bone or joint relations problems or have a recent history of heart, liver or kidney diseases, glaucoma, cataracts, nasal surgery, chronic nasal inflammation, insomnia, or mood swings, inform your doctor before receiving DEPOCILONE-40MG/1ML INJECTION. This medicine may cause dizziness; hence, it is advised to avoid driving vehicles or operating machines after receiving this injection.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Depocilone 40 mg Injection 1 ml:
Co-administration of desmopressin together with Depocilone 40 mg Injection 1 ml may increase the risk of hyponatremia (a condition associated with low levels of salt in the blood).

How to manage the interaction:
Taking Depocilone 40 mg Injection 1 ml with Desmopressin is not recommended, but it should be taken if advised by a doctor. However, if you experience nausea, vomiting, headache, tiredness, irritability, difficulty concentrating, confusion, muscle spasm, weakness, , decreased urination and loss of appetite(less desire to eat), contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Depocilone 40 mg Injection 1 ml:
Using Mifepristone with Depocilone 40 mg Injection 1 ml can significantly reduce the effects of Depocilone 40 mg Injection 1 ml.

How to manage the interaction:
Taking Depocilone 40 mg Injection 1 ml with Mifepristone is not recommended but can be taken if prescribed by a doctor. However, if you notice any unusual symptoms contact a doctor. Do not discontinue any medications without consulting a doctor.
TriamcinoloneDesirudin
Severe
How does the drug interact with Depocilone 40 mg Injection 1 ml:
Using desirudin together with Depocilone 40 mg Injection 1 ml may increase the risk of bleeding

How to manage the interaction:
Although taking Depocilone 40 mg Injection 1 ml and Desirudin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Depocilone 40 mg Injection 1 ml:
Coadministration of Gatifloxacin with Depocilone 40 mg Injection 1 ml can increase the risk or severity of tendinitis (inflammation of the tendons attached to the muscle and bones).

How to manage the interaction:
Taking Gatifloxacin with Depocilone 40 mg Injection 1 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Depocilone 40 mg Injection 1 ml:
Depocilone 40 mg Injection 1 ml blood levels can rise when itraconazole and Depocilone 40 mg Injection 1 ml are used together.

How to manage the interaction:
Depocilone 40 mg Injection 1 ml and itraconazole may interact, but if a doctor prescribes them, you can still use them. However, if you experience Swelling, high blood sugar, muscle weakness, depression, acne, stretch marks, easy bruising, bone density loss, irregular menstruation, and excessive face or body hair growth contact a doctor immediately. Do not discontinue taking a medication without consulting a doctor.
How does the drug interact with Depocilone 40 mg Injection 1 ml:
Combining Depocilone 40 mg Injection 1 ml with Moxifloxacin can increase the risk of tendinitis(a condition in which the tissue connecting muscle to bone becomes inflamed) and tendon rupture(injuries to the soft tissues that connect muscles and joints).

How to manage the interaction:
Co-administration of Depocilone 40 mg Injection 1 ml with Moxifloxacin can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, or biceps, consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Depocilone 40 mg Injection 1 ml:
Coadministration of Norfloxacin with Depocilone 40 mg Injection 1 ml can increase the risk or severity of tendinitis (inflammation of the tendons attached to the muscle and bones).

How to manage the interaction:
Taking Norfloxacin with Depocilone 40 mg Injection 1 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Depocilone 40 mg Injection 1 ml:
Taking Depocilone 40 mg Injection 1 ml with leflunomide can increase the risk of infection.

How to manage the interaction:
Although there is an interaction between Leflunomide and Depocilone 40 mg Injection 1 ml, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, pain or burning during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Depocilone 40 mg Injection 1 ml:
Using cladribine with Depocilone 40 mg Injection 1 ml can increase the risk of serious infections.

How to manage the interaction:
Co-administration of Cladribine with Depocilone 40 mg Injection 1 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Depocilone 40 mg Injection 1 ml:
Taking infliximab with Depocilone 40 mg Injection 1 ml can increase the risk or severity of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Depocilone 40 mg Injection 1 ml and Infliximab, you can take these medicines together if prescribed by your doctor. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Perform gentle activities like 20-30 minutes of walking or swimming. Physical activity helps strengthen muscles and relieves joint stiffness.
  • Perform yoga as it may help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Limit salt intake and prefer herbs or spices like garlic, ginger, and turmeric, which are natural anti-inflammatory agents.
  • Try to avoid alcohol, as it can affect your stomach and intestine and limit the absorption of the essential nutrients required by your body.

Habit Forming

No

Therapeutic Class

CORTICOSTEROIDS
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Alcohol

Caution

Avoid consumption of alcohol while on treatment with DEPOCILONE-40MG/1ML INJECTION as it may increase adverse effects.

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Pregnancy

Caution

Inform your doctor if you are pregnant or planning to become pregnant before taking DEPOCILONE-40MG/1ML INJECTION. Your doctor will prescribe this medicine only if the benefits outweigh the potential risks.

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Breast Feeding

Caution

Limited information is available on the effects of DEPOCILONE-40MG/1ML INJECTION on breastfeeding. Hence, inform your doctor if you are a nursing or breastfeeding mother. Your doctor will administer this medicine only if the benefits outweigh the potential risks.

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Driving

Caution

DEPOCILONE-40MG/1ML INJECTION may cause dizziness. So, do not drive, operate heavy machinery or refrain from activities that require your alertness.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before receiving DEPOCILONE-40MG/1ML INJECTION. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Before receiving $ name, let your doctor know if you have any history of kidney diseases. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

DEPOCILONE-40MG/1ML INJECTION is not recommended for use in children below 12 years of age. Please consult your doctor for more information.

Have a query?

FAQs

DEPOCILONE-40MG/1ML INJECTION is used to treat the pain of osteoarthritis (OA) in the knee.

DEPOCILONE-40MG/1ML INJECTION works by blocking the release of certain chemical messengers involved in allergic and non-allergic-mediated inflammation. It also makes the nasal passages less sensitive to allergic triggers like pollen, animal dander or dust mites.

DEPOCILONE-40MG/1ML INJECTION works by blocking the release of certain chemical messengers involved in allergic and non-allergic-mediated inflammation. This helps reduce osteoarthritis symptoms such as pain, inflammation, swelling, and stiffness.

DEPOCILONE-40MG/1ML INJECTION weakens your immune system and increases the risk of getting infections. So, make sure you stay away from people who are sick or have infections. These conditions are life-threatening in people using steroids such as DEPOCILONE-40MG/1ML INJECTION.

Do not stop using DEPOCILONE-40MG/1ML INJECTION even if you feel better, as it may worsen your condition. However, if you experience any difficulty while using DEPOCILONE-40MG/1ML INJECTION, please consult a doctor.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - DEP0250

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