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  3. Depishine-TX Tablet 10's

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Depishine-TX Tablet 10's, Pack of 10
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Depishine-TX Tablet is used to control bleeding in conditions like menorrhagia (heavy or prolonged menstrual bleeding) and nose bleeds. It works by preventing the breakdown of fibrin (a protein that is involved in blood clotting), thereby, it helps prevent bleeding. Besides this, it also exerts anti-inflammatory properties. In some cases, this medicine may cause side effects like nausea, diarrhoea, and itchy red skin.
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Composition :

PINE BARK EXTRACT-50MG + TRANEXAMIC ACID-250MG

Manufacturer/Marketer :

Livia Healthcare Llp

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Depishine-TX Tablet

Depishine-TX Tablet belongs to the class of medications called ‘Anti-hemorrhagic agents’ used to control bleeding, especially for menorrhagia and nose bleeds. Menorrhagia is a medical condition where menstrual bleeding lasts longer than seven days. It could be intense bleeding. The loss of blood that occurs from the tissue that lines the inside of your nose is known as a nosebleed.

Depishine-TX Tablet is a combination of two medicines: tranexamic acid and pine bark extract. Tranexamic acid is an anti-fibrinolytic medication. It aids in the prevention of fibrinolysis by preventing the breakdown of fibrin. Pine bark extract has essential anti-inflammatory and anti-thrombotic properties that may benefit patients with haemorrhoids, both acute and chronic treatment. Thereby Depishine-TX Tablet treats heavy bleeding.

You should use this medicine as prescribed by your doctor. Most people do not have any side effects while taking Depishine-TX Tablet . However, in a few cases, it may cause side effects such as nausea (feeling sick), diarrhoea, and itchy red skin. The majority of these side effects do not necessitate medical treatment and will subside gradually over time. However, if you regularly have these adverse effects, you should seek medical attention.

Depishine-TX Tablet is not suitable for some people. To ensure that Depishine-TX Tablet is safe for you, tell your doctor if you have ever had an allergic reaction to tranexamic acid, pine bark extract, or any other medicine, if you have a history of kidney problems, DVT (deep vein thrombosis) or pulmonary embolism (blocked blood vessel in your lungs), coagulopathy (a rare condition where lots of small blood clots form in your blood followed by abnormal bleeding), epilepsy, irregular periods, and visual disturbances. Also, inform your doctor if you are pregnant or breastfeeding.

Uses of Depishine-TX Tablet

Treatment of Menorrhagia and Nose bleeding.

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Directions for Use

• Depishine-TX Tablet can be taken with or without food, as advised by your doctor.• It is usually taken 3 times a day or as prescribed by your doctor.• Swallow the whole Depishine-TX Tablet with a glass of water.• Do not break, chew, or crush it.

Medicinal Benefits

Depishine-TX Tablet contains tranexamic acid and pine bark extract. Tranexamic acid is an anti-fibrinolytic medication. It aids in the prevention of fibrinolysis by preventing the breakdown of fibrin. Pine bark extract has essential anti-inflammatory and anti-thrombotic properties that may benefit patients with haemorrhoids, both acute and chronic treatment. Thereby Depishine-TX Tablet treats heavy bleeding.

How Depishine-TX Tablet Works

Depishine-TX Tablet is a combination of two medicines: tranexamic acid and pine bark extract. Tranexamic acid is an anti-fibrinolytic medication. It aids in the prevention of fibrinolysis by preventing the breakdown of fibrin. Pine bark extract has essential anti-inflammatory and anti-thrombotic properties that may benefit patients with haemorrhoids, both acute and chronic treatment. Thereby Depishine-TX Tablet treats heavy bleeding.

Storage

Keep out of the sight and reach of children.
Side effects of Depishine-TX Tablet
  • Muscle cramps can be treated with regular exercise or yoga, which includes mild stretching, which helps strengthen the lower body.
  • Warm baths and gentle massage of the affected parts can help relieve cramps.
  • Avoid strenuous activity and take frequent breaks, as rest is critical.
  • Intake of nutritious food can help strengthen body and mind. A trained nutritionist can help design a balanced diet for strengthening muscles.
  • Speak to your doctor if the pain lasts an extended period. Medical help can be practical in finding a cure for cramps.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your allergic sinusitis symptoms.
  • Stay hydrated by drinking plenty of water to thin out mucus and facilitate nasal passage clearance.
  • Inhale steam from a hot shower or bowl of hot water to loosen mucus and alleviate congestion.
  • Practice good hygiene by washing your hands frequently, avoid close contact with others, and refraining from sharing personal items or utensils.
  • If advised by your doctor, consider using nasal decongestants or saline nasal sprays to relieve nasal congestion and sinus pressure.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Depishine-TX Tablet

Take Depishine-TX Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Depishine-TX Tablet is not suitable for some people. To ensure that Depishine-TX Tablet is safe for you, tell your doctor if you have ever had an allergic reaction to tranexamic acid, pine bark extract, or any other medicine, if you have a history of kidney problems, DVT (deep vein thrombosis) or pulmonary embolism (blocked blood vessel in your lungs), coagulopathy (a rare condition where lots of small blood clots form in your blood followed by abnormal bleeding), epilepsy, irregular periods, and visual disturbances. And also, inform your doctor if you are pregnant or breastfeeding. 

Drug-Drug Interactions

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Tranexamic acidDrospirenone
Critical
Tranexamic acidEtonogestrel
Critical

Drug-Drug Interactions

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Tranexamic acidDrospirenone
Critical
How does the drug interact with Depishine-TX Tablet:
Taking drospirenone with Depishine-TX Tablet may increase the risk of blood clot formation.

How to manage the interaction:
Taking Depishine-TX Tablet with Drospirenone is not recommended, as it can lead to an interaction but can be taken if prescribed by the doctor. However, If you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult your doctor immediately.
Tranexamic acidEtonogestrel
Critical
How does the drug interact with Depishine-TX Tablet:
Co-administration of Depishine-TX Tablet may cause blood clotting when taken with Etonogestrel.

How to manage the interaction:
Taking Depishine-TX Tablet with Etonogestrel is not recommended, as it can lead to an interaction but can be taken if prescribed by the doctor. However, If you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult your doctor immediately.
Tranexamic acidEthinylestradiol
Critical
How does the drug interact with Depishine-TX Tablet:
Taking Ethinylestradiol with Depishine-TX Tablet may increase the risk of blood clot formation.

How to manage the interaction:
Taking Ethinylestradiol with Depishine-TX Tablet is not recommended, as it can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult doctor immediately. Do not stop using any medications without talking to a doctor.
Tranexamic acidLevonorgestrel
Critical
How does the drug interact with Depishine-TX Tablet:
Taking Levonorgestrel with Depishine-TX Tablet may increase the risk of blood clot formation which can lead to serious conditions such as heart problems and kidney failure.

How to manage the interaction:
Taking Depishine-TX Tablet with Levonorgestrel may leads to an interaction but can be taken if prescribed by the doctor. However, if you experience chest pain; shortness of breath; coughing up blood; blood in the urine; sudden loss of vision; and pain, redness, or swelling in your arm or leg, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Tranexamic acidMedroxyprogesterone
Critical
How does the drug interact with Depishine-TX Tablet:
Taking Medroxyprogesterone acetate with Depishine-TX Tablet may increase the risk of blood clots.

How to manage the interaction:
Taking Medroxyprogesterone with Depishine-TX Tablet is not recommended but can be taken if prescribed by a doctor. Consult your doctor immediately if you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg. Do not stop using any medications without talking to your doctor.
Tranexamic acidEstrone
Severe
How does the drug interact with Depishine-TX Tablet:
Co-administration of Estrone with Depishine-TX Tablet can increase the risk of blood clots.

How to manage the interaction:
Taking Estrone with Depishine-TX Tablet can possibly lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tranexamic acidEstramustine
Severe
How does the drug interact with Depishine-TX Tablet:
Co-administration of Estramustine with Depishine-TX Tablet can increase the risk of blood clots.

How to manage the interaction:
Taking Estramustine with Depishine-TX Tablet possibly lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tranexamic acidTamoxifen
Severe
How does the drug interact with Depishine-TX Tablet:
Co-administration of tamoxifen with Depishine-TX Tablet can increase the risk of blood clots.

How to manage the interaction:
Although taking tamoxifen and Depishine-TX Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
Tranexamic acidDiethylstilbestrol
Severe
How does the drug interact with Depishine-TX Tablet:
Co-administration of Diethylstilbestrol with Depishine-TX Tablet can increase the risk of blood clots.

How to manage the interaction:
Taking Diethylstilbestrol with Depishine-TX Tablet can possibly lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tranexamic acidNorethisterone
Severe
How does the drug interact with Depishine-TX Tablet:
Using Depishine-TX Tablet together with norethindrone may increase the risk of blood clots.

How to manage the interaction:
Taking norethisterone with Depishine-TX Tablet can lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg, contact a doctor immediately .Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Drink plenty of fluids to stay hydrated. Fluids are necessary to maintain blood flow in your body.
  • Include a diet that includes omega–3 fatty acids, Fiber, and Antioxidants such as flaxseeds, fruits, vegetables, nuts, and beans.
  • Instead of saturated and trans-fats, choose monounsaturated and polyunsaturated fats (fish, nuts, and vegetable oils).
  • Select/prepare foods and beverages with less added sugars/caloric sweeteners.
  • Limit or avoid alcohol consumption.
  • Avoid physical and psychological stress.
  • Replace fatty protein sources with lean alternatives and consume modest quantities of healthy fat sources for improved wellbeing.

Habit Forming

No

Therapeutic Class

ANTIHEMORRHAGIC AGENTS

Depishine-TX Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

No interaction was found. However, it is best to avoid alcohol while taking medication as a precautionary measure.

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Pregnancy

Caution

There are no adequate and well-controlled pregnancy studies. Your doctor will only prescribe if the benefits outweigh the risks.

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Breast Feeding

Caution

Tranexamic acid may be present in trace concentrations in breast milk. However, please consult a doctor if you are a breastfeeding mother.

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Driving

Caution

Depishine-TX Tablet will not impair your ability to drive or operate machines. However, do not drive if you experience any symptoms that affect your ability to concentrate and react.

bannner image

Liver

Safe if prescribed

Depishine-TX Tablet is probably safe in patients with liver diseases. Consult your doctor for further advice if you have any concerns about this.

bannner image

Kidney

Caution

Depishine-TX Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Children

Caution

Limited information is available for the use of Depishine-TX Tablet in pediatric patients. Your doctor will prescribe only if the benefits outweigh the risks.

FAQs

Depishine-TX Tablet is used to control bleeding, especially for menorrhagia (menstrual bleeding lasts longer than seven days) and nose bleeds.

Depishine-TX Tablet contains tranexamic acid and pine bark extract. Tranexamic acid is an anti-fibrinolytic medication. It aids in the prevention of fibrinolysis by preventing the breakdown of fibrin. This aids in the retention of blood clots in areas where they are required. Pine bark extract has essential anti-inflammatory and anti-thrombotic properties that may benefit patients with hemorrhoids, both acute and chronic treatment. Thereby Depishine-TX Tablet treats heavy bleeding.

Caution should be exercised while using Depishine-TX Tablet in patients with pulmonary embolism (blocked blood vessels in your lungs). Let your doctor know about your present health condition before taking Depishine-TX Tablet .

If you get diarrhoea after using the Depishine-TX Tablet , drink plenty of water to avoid dehydration. If it persists, consult your doctor. Without a doctor's prescription, do not attempt to take antidiarrheal medication.

Depishine-TX Tablet is usually used for a short time to treat bleeding. You are recommended to take Depishine-TX Tablet for as long as it is prescribed by a doctor to treat heavy periods. If you notice no improvement, please consult your doctor.

Yes, Depishine-TX Tablet is used to control excessive bleeding during heavy menstrual periods. However, please consult your doctor before taking Depishine-TX Tablet .

Depishine-TX Tablet may cause gastrointestinal side effects, including loose stools or diarrhoea, in some individuals. However, this is not a universal experience and may vary depending on individual tolerance and sensitivity. Consult your healthcare professional for guidance if you experience persistent or severe loose stools.

The common side effects of Depishine-TX Tablet are nausea (feeling sick), diarrhoea, itchy red skin, stomach upset and headache. Please consult your doctor if any of these side effects persist or worsen.

Depishine-TX Tablet should be used with caution in pregnant women only if prescribed by the doctor. Therefore, inform your doctor immediately if you become pregnant or think you may be pregnant before taking Depishine-TX Tablet . Your doctor will only prescribe if the benefits outweigh the risks.

Country of origin

India

Manufacturer/Marketer address

Level 17, Dlh Park, Ramlal Compound, Swami Vivekananda Rd, Goregaon West, Mumbai, Maharashtra 400064
Other Info - DEP0228

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 18, 2025 | 6:54 AM IST

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Reference

  1. https://www.eurekalert.org/news-releases/864232
  2. https://www.nhs.uk/medicines/tranexamic-acid/

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